y 27632 has been researched along with angiotensin ii in 40 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (angiotensin ii) | Trials (angiotensin ii) | Recent Studies (post-2010) (angiotensin ii) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 38,152 | 1,089 | 7,413 |
| Protein | Taxonomy | y 27632 (IC50) | angiotensin ii (IC50) |
|---|---|---|---|
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.002 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.002 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0018 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0055 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.004 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 23 (57.50) | 29.6817 |
| 2010's | 17 (42.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Ichihara, S; Inagami, T; Motley, ED; Numaguchi, K; Tanaka, S; Yamakawa, T; Yamakawa, Y | 1 |
| Hisaoka, T; Kobayashi, S; Kohno, M; Matsuzaki, M; Ohkusa, T; Ono, K; Suetsugu, M; Yamada, J; Yano, M | 1 |
| Egashira, K; Funakoshi, Y; Ichiki, T; Kaibuchi, K; Shimokawa, H; Takeda, K; Takeshita, A; Takeya, M; Yoshimura, T | 1 |
| Gorny, D; Henrion, D; Levy, BI; Loufrani, L; Matrougui, K; Tankó, LB; Tedgui, A | 1 |
| Honda, T; Kobayashi, N; Kobayashi, T; Matsuoka, H; Mita, S; Nakano, S; Tsubokou, Y | 1 |
| Cho, KW; Kim, SH; Kim, YG; Koh, GY; Lee, SO; Park, JK | 1 |
| Hartshorne, DJ; Isaka, N; Ito, M; Kureishi, Y; Moriki, N; Nakano, T; Okamoto, R; Onishi, K; Seko, T | 1 |
| Jin, L; Linder, AE; Mills, TM; Webb, RC | 1 |
| Bauer, J; Parekh, N | 1 |
| Barth, H; Bolz, SS; Galle, J; Gambaryan, S; Görg, M; Mameghani, A; Pohl, U; Quaschning, T; Raff, U; Seibold, S; Wanner, C | 1 |
| Didion, SP; Faraci, FM; Mathur, S; Ryan, MJ; Sigmund, CD | 1 |
| Arikan, O; Ark, M; Büyükafşar, K; Kubat, H; Ozveren, E | 1 |
| Hatta, T; Irie, H; Kameyama, H; Kusaba, T; Kuwahara, N; Matsubara, H; Narumiya, H; Sasaki, S; Takeda, K; Tamagaki, K | 1 |
| Blanco-Colio, LM; Egido, J; Esteban, V; Plaza, JJ; Rodríguez-Vita, J; Ruiz-Ortega, M; Rupérez, M; Sánchez-López, E | 1 |
| Hilgers, RH; Imig, JD; Jin, L; Webb, RC; Yin, J; Ying, Z; Zhao, X | 1 |
| Adachi, S; Isobe, M; Ito, H; Kitajima, S; Maejima, Y; Morikawa-Futamatsu, K; Suzuki, J; Tamamori-Adachi, M | 1 |
| Hirooka, Y; Ito, K; Kimura, Y; Nozoe, M; Sagara, Y; Sunagawa, K | 1 |
| Ahuja, P; Ehler, E; Pedrazzini, T; Perriard, E; Perriard, JC; Satoh, S | 1 |
| Hilgers, RH; Todd, J; Webb, RC | 1 |
| Hibi, T; Horikawa, H; Ishii, H; Kitamura, K; Kumagai, N; Kurita, S; Nakamoto, N; Saito, H; Tada, S; Toda, K; Tsunematsu, S | 1 |
| Lai, EY; Nordquist, L; Patzak, A; Persson, AE; Sjöquist, M | 1 |
| Benoit, M; Cuerrier, CM; Gobeil, F; Grandbois, M; Guillemette, G | 1 |
| Dimaio, JM; Gerard, RD; Kinoshita, H; Kuwahara, K; Olson, EN; Richardson, JA; Sadek, H; Small, EM; Sutherland, LB; Thatcher, JE | 1 |
| Caldwell, RB; Caldwell, RW; Chandra, S; Iddings, JA; Romero, MJ; Shatanawi, A; Umapathy, NS; Verin, AD | 1 |
| Hatano, Y; Ogawa, K; Tange, K; Tokinaga, Y; Uematsu, N | 1 |
| Cai, SX; Li, X; Meng, Y; Tong, WC | 1 |
| Cheng, YX; Lai, WY; Li, N; Li, X; Meng, Y; Niu, Y; Shen, B | 1 |
| Das, J; Gutkind, JS; Ray, PE; Short, BL; Xie-Zukauskas, H | 1 |
| Li, T; Liang, JL; Liu, LM; Yang, GM | 1 |
| Boucher, J; Froehlich, U; Grandbois, M; Simard, E | 1 |
| Grzesk, E; Grzesk, G; Jasinski, M; Slupski, M; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R; Wlodarczyk, Z; Woderska, A | 1 |
| Chang, L; Guo, B; Jin, X; Li, Y; Liu, S; Miao, C; Wang, Y; Yan, J; Yang, R; Zhang, H | 1 |
| Chen, HS; Jiang, FY; Li, RS; Li, WJ; Tu, Q; Wang, Y; Yin, RX | 1 |
| Seawright, JW; Trache, A; Wilson, E; Woodman, CR | 1 |
| Assreuy, J; da Silva, LM; da Silva-Santos, JE; de Souza, P; Guarido, KL; Scheschowitsch, K; Werner, MF | 1 |
| Chen, J; Chen, XM; Hou, JW; Li, G; Li, W; Li, YG; Wang, H; Wang, Q; Wang, YP; Wei, SS; Xu, WP; Zhou, Q | 1 |
| Islam, MZ; Miyamoto, A; Shiraishi, M; Van Dao, C | 1 |
| De Silva, TM; Faraci, FM; Hu, C; Kinzenbaw, DA; Modrick, ML; Sigmund, CD | 1 |
| Fan, SH; Li, XW; Niu, Y; Shi, YW; Xiong, QF; Zhang, LH; Zhang, X | 1 |
1 review(s) available for y 27632 and angiotensin ii
| Article | Year |
|---|---|
Inhibition of the tonic contraction in the treatment of erectile dysfunction.
Topics: Adrenergic Agonists; Adult; Aged; Aging; Amides; Angiotensin II; Calcium Signaling; Cyclic AMP; Endothelin-1; Erectile Dysfunction; Forecasting; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoactive Intestinal Peptide | 2003 |
39 other study(ies) available for y 27632 and angiotensin ii
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells.
Topics: ADP Ribose Transferases; Amides; Angiotensin II; Animals; Aorta, Thoracic; Biological Transport; Botulinum Toxins; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Gene Expression; Hypertrophy; Intracellular Signaling Peptides and Proteins; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger | 2000 |
Enhancement of Rho/Rho-kinase system in regulation of vascular smooth muscle contraction in tachycardia-induced heart failure.
Topics: Amides; Analysis of Variance; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cardiac Pacing, Artificial; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Femoral Artery; Heart Failure; Immunoblotting; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nifedipine; Protein Serine-Threonine Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein | 2001 |
Rho-kinase mediates angiotensin II-induced monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells.
Topics: Amides; Angiotensin II; Animals; Cells, Cultured; Chemokine CCL2; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger | 2001 |
Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries.
Topics: Actin Cytoskeleton; Amides; Angiotensin II; Animals; Cytochalasin B; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2001 |
Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Hemodynamics; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2002 |
Role of rho-kinase activity in angiotensin II-induced contraction of rabbit clitoral cavernosum smooth muscle.
Topics: Amides; Angiotensin II; Animals; Azepines; Clitoris; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Naphthalenes; Nitric Oxide; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2002 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents | 2003 |
Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.
Topics: ADP Ribose Transferases; Amides; Angiotensin II; Animals; Aorta; Biological Transport; Cattle; Cells, Cultured; Clostridium; Drug Synergism; Felodipine; Female; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lipoproteins, LDL; Losartan; Lysophosphatidylcholines; Male; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Amides; Angiotensin II; Animals; Aorta; Carotid Arteries; Infusion Pumps, Implantable; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitroprusside; Papaverine; Phenylephrine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Sequence Deletion; Serotonin; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats.
Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blotting, Western; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mesenteric Arteries; Nitrates; Nitrites; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Chloride; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
Topics: Amides; Analysis of Variance; Angiotensin II; Atorvastatin; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucuronidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules; Klotho Proteins; Membrane Proteins; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; RNA, Messenger | 2004 |
The Rho-kinase pathway regulates angiotensin II-induced renal damage.
Topics: Amides; Angiotensin II; Animals; Blotting, Western; Chemokine CCL2; Connective Tissue Growth Factor; Enzyme Inhibitors; Female; Gene Expression Regulation; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; NF-kappa B; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Rho Factor; rho-Associated Kinases; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Activation; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; NADPH Oxidases; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2006 |
HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.
Topics: Adenoviridae Infections; Amides; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Cyclin D1; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Indoles; Intracellular Signaling Peptides and Proteins; Leucine; Male; Mevalonic Acid; Myocardium; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger | 2006 |
Pressor response induced by central angiotensin II is mediated by activation of Rho/Rho-kinase pathway via AT1 receptors.
Topics: Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain Stem; Heart Rate; Intracellular Signaling Peptides and Proteins; Norepinephrine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; rho-Associated Kinases; rhoA GTP-Binding Protein; Sympathetic Nervous System | 2007 |
Re-expression of proteins involved in cytokinesis during cardiac hypertrophy.
Topics: Actomyosin; Amides; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Calpain; Cardiomegaly; Cell Nucleus Division; Cullin Proteins; Cytokinesis; Heart; Hypertension; Intracellular Signaling Peptides and Proteins; Mice; Myocytes, Cardiac; Myofibrils; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; rho GTP-Binding Proteins; rho-Associated Kinases; Up-Regulation | 2007 |
Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Calcium; DNA Primers; Guanine Nucleotide Exchange Factors; Hypertension; Immunoprecipitation; Mesenteric Arteries; Myosin-Light-Chain Phosphatase; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Signal Transduction | 2007 |
Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis.
Topics: Alanine Transaminase; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aspartate Aminotransferases; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Choline Deficiency; Disease Models, Animal; DNA Damage; Fatty Liver; Liver; Liver Cirrhosis; Male; Organ Size; Oxidative Stress; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Tetrazoles; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism.
Topics: Amides; Angiotensin II; Animals; Arterioles; C-Peptide; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glomerulus; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Norepinephrine; Potassium Chloride; Pyridines; Rho Factor; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy.
Topics: Actins; Amides; Angiotensin II; Azepines; Cell Line; Cell Size; Cytological Techniques; Cytoskeleton; Elastic Modulus; Heterocyclic Compounds, 4 or More Rings; Humans; Kidney; Microscopy, Atomic Force; Microscopy, Confocal; Muscle Contraction; Pyridines; Receptor, Angiotensin, Type 1 | 2009 |
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Cell Transdifferentiation; Chlorocebus aethiops; Collagen; Collagen Type I; COS Cells; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Male; Mice; Mice, Knockout; Molecular Sequence Data; Myocardial Infarction; Myocardium; Myocytes, Smooth Muscle; Phenotype; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta1; Ventricular Remodeling | 2010 |
Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginase; Boronic Acids; Cattle; Cell Line; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; Imidazoles; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Simvastatin | 2011 |
Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat.
Topics: Amides; Anesthetics, Inhalation; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Calcium Signaling; Enzyme Inhibitors; In Vitro Techniques; Isometric Contraction; Male; Methyl Ethers; Muscle Contraction; Muscle, Smooth, Vascular; Protein Transport; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Sevoflurane | 2011 |
[Production of connective tissue growth factor by angiotensin II in human embryonic lung fibroblast via RhoA-ROCK pathway].
Topics: Amides; Angiotensin II; Cell Line; Connective Tissue Growth Factor; Fibroblasts; Humans; Lung; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2011 |
[Activation of Rho-kinase pathway is involved in angiotensin II-induced contraction of human airway smooth muscle cells].
Topics: Amides; Angiotensin II; Asthma; Biphenyl Compounds; Bronchi; Humans; Irbesartan; Muscle Contraction; Muscle, Smooth; Primary Cell Culture; Pyridines; rho-Associated Kinases; Signal Transduction; Tetrazoles | 2011 |
Heparin inhibits angiotensin II-induced vasoconstriction on isolated mouse mesenteric resistance arteries through Rho-A- and PKA-dependent pathways.
Topics: Amides; Angiotensin II; Animals; Anticoagulants; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Heparin; Male; Mesenteric Arteries; Mice; Myosin Light Chains; Phosphorylation; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction | 2013 |
Effects of interleukin-1β on vascular reactivity after lipopolysaccharide-induced endotoxic shock in rabbits and its relationship with PKC and Rho kinase.
Topics: Amides; Angiotensin II; Animals; Arterial Pressure; Blood Vessels; Calcium Signaling; Humans; Interleukin-1beta; Lipopolysaccharides; Mesenteric Arteries; Phosphorylation; Protein Kinase C; Pyridines; Rabbits; Recombinant Proteins; rho-Associated Kinases; Shock, Septic; Tetradecanoylphorbol Acetate | 2013 |
Amplification of AngII-dependent cell contraction by glyoxal: implication of cell mechanical properties and actomyosin activity.
Topics: Actin Cytoskeleton; Actomyosin; Amides; Angiotensin II; Glycation End Products, Advanced; Glyoxal; HEK293 Cells; Humans; Microscopy, Atomic Force; Microscopy, Fluorescence; Myosin Light Chains; Phosphorylation; Pyridines | 2014 |
Rho-kinase inhibitor reduces hypersensitivity to ANG II in human mesenteric arteries retrieved and conserved under the same conditions as transplanted organs.
Topics: Amides; Angiotensin II; Cadaver; Calcium; Enzyme Inhibitors; Humans; Hypersensitivity; Mesenteric Arteries; Pyridines; Reperfusion Injury; rho-Associated Kinases; Tissue Preservation | 2014 |
Angiotensin II increases secreted frizzled-related protein 5 (sFRP5) expression through AT1 receptor/Rho/ROCK1/JNK signaling in cardiomyocytes.
Topics: Adipokines; Amides; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Proteins; Myocytes, Cardiac; Pyridines; Rats; Tumor Necrosis Factor-alpha | 2015 |
TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway.
Topics: Amides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anoctamin-1; Basilar Artery; Cells, Cultured; Chloride Channels; Disease Models, Animal; Evoked Potentials; Hypertension; Male; Muscle, Smooth, Vascular; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction | 2016 |
Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries.
Topics: Aging; Amides; Angiotensin II; Animals; Arteries; Endothelium, Vascular; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Pressure; Pyridines; Rats; Rats, Inbred F344; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2016 |
Impaired vascular function in sepsis-surviving rats mediated by oxidative stress and Rho-Kinase pathway.
Topics: Amides; Angiotensin II; Animals; Aorta, Thoracic; Endothelium, Vascular; Male; Oxidative Stress; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; rho-Associated Kinases; Sepsis; Signal Transduction; Superoxide Dismutase | 2016 |
Crucial Role of ROCK2-Mediated Phosphorylation and Upregulation of FHOD3 in the Pathogenesis of Angiotensin II-Induced Cardiac Hypertrophy.
Topics: Amides; Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Formins; Male; Microfilament Proteins; Myocytes, Cardiac; Phosphorylation; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Up-Regulation | 2017 |
Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice.
Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; rho-Associated Kinases; Streptozocin; Time Factors | 2017 |
Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7.
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Carotid Arteries; Female; Interleukin-6; Male; Mice; NF-kappa B; Oxidative Stress; Peptide Fragments; PPAR gamma; Pyridines; Renin-Angiotensin System; Vascular Diseases; Vasoconstrictor Agents; Vasodilation | 2017 |
GLP-1 attenuates Ang II-induced proliferation and migration in rat aorta smooth muscle cells
Topics: Amides; Angiotensin II; Animals; Aorta; Cell Movement; Cell Proliferation; Cells, Cultured; Colforsin; Glucagon-Like Peptide 1; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2018 |