Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and aldosterone

y 27632 has been researched along with aldosterone in 5 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(aldosterone)		Trials
(aldosterone)		Recent Studies (post-2010) (aldosterone)
1,924389125,3331,5174,169

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)aldosterone (IC50)
Mineralocorticoid receptor Homo sapiens (human)0.0048
Mineralocorticoid receptorRattus norvegicus (Norway rat)0.043

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diah, S; Gang, L; Hamid, MR; Hitomi, H; Kimura, S; Nagai, Y; Nishiyama, A; Tamiya, T; Zhang, GX; Zhang, W1
Guo, P; Hitomi, H; Hosomi, N; Kagami, S; Kimura, S; Kiyomoto, H; Kohno, M; Miyata, K; Nishiyama, A; Zhang, GX1
Ji, H; Li, X; Luo, W; Meng, Y; Wu, P; Xiao, B; Zhang, X; Zhang, Z1
Chen, D; Han, H; Huang, Y; Li, W; Li, Z; Ma, C; Peng, Y; Wei, J; Wu, W; Zhan, F1
Ji, H; Wang, B1

Other Studies

5 other study(ies) available for y 27632 and aldosterone

ArticleYear
Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells.
    Experimental cell research, 2008, Dec-10, Volume: 314, Issue:20

    Topics: Aldosterone; Amides; Animals; Cell Transdifferentiation; Collagen; Eplerenone; Gene Expression Regulation; Hypertrophy; Mesangial Cells; Mineralocorticoid Receptor Antagonists; Muscle Development; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; rho-Associated Kinases; Signal Transduction; Spironolactone

2008
Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:7

    Topics: Actins; Aldosterone; Amides; Animals; Cell Movement; Cells, Cultured; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

2008
Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway.
    Regulatory peptides, 2011, Aug-08, Volume: 169, Issue:1-3

    Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cell Size; Cells, Cultured; Hepatic Stellate Cells; Irbesartan; Male; Mineralocorticoid Receptor Antagonists; Myosin Light Chains; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Spironolactone; Stress Fibers; Tetrazoles

2011
Rho kinase pathway is likely responsible for the profibrotic actions of aldosterone in renal epithelial cells via inducing epithelial-mesenchymal transition and extracellular matrix excretion.
    Cell biology international, 2013, Volume: 37, Issue:7

    Topics: Actins; Aldosterone; Amides; Cadherins; Cell Line; Collagen Type I; Collagen Type III; Epithelial Cells; Epithelial-Mesenchymal Transition; Eplerenone; Extracellular Matrix; Gene Expression Regulation; Humans; Kidney; Mineralocorticoid Receptor Antagonists; Protein Kinase Inhibitors; Pyridines; Receptors, Mineralocorticoid; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Spironolactone

2013
[Aldosterone promotes migration of rat hepatic stellate cells via activation of RhoA/ROCK signaling pathway].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:9

    Topics: Aldosterone; Amides; Animals; Cell Movement; Cells, Cultured; Hepatic Stellate Cells; Pyridines; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Spironolactone

2019