y 27632 and ag 1879

Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Animals; Binding, Competitive; Catalytic Domain; Cell-Free System; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Databases, Factual; Genes, Reporter; Luciferases; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Recombinant Fusion Proteins; Structure-Activity Relationship

Topics: Actins; Amides; Blotting, Western; Breast Neoplasms; Butadienes; Carcinoma; Catalysis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; CSK Tyrosine-Protein Kinase; Culture Media, Serum-Free; Depsipeptides; Down-Regulation; Fibronectins; Flow Cytometry; Humans; Immunoprecipitation; Insulin-Like Growth Factor I; Integrin alpha5beta1; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Microscopy, Phase-Contrast; Models, Biological; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; src-Family Kinases; Time Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Amides; Apyrase; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Humans; Integrin alpha2; Intracellular Signaling Peptides and Proteins; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Purinergic P2; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Signal Transduction; Tyrosine

Topics: Amides; Animals; Arteries; Calcium; Dose-Response Relationship, Drug; Endothelin-1; Foot; Intracellular Signaling Peptides and Proteins; Phenylephrine; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Pyrimidines; rho-Associated Kinases; Serotonin; Signal Transduction; src-Family Kinases; Vasoconstriction; Vasoconstrictor Agents; Veins

Topics: Actins; Amides; Aminoquinolines; Animals; Cell Adhesion; Cell Shape; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Focal Adhesions; Gene Expression; Mesangial Cells; Microtubules; Nocodazole; Paxillin; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Thrombospondin 1

Topics: Amides; Androstadienes; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Endothelial Cells; Estrenes; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Furans; Human Umbilical Vein Endothelial Cells; Humans; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Progesterone; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Receptors, Progesterone; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Wortmannin

Topics: Amides; Cell Movement; Cells, Cultured; Chemotaxis; Chromones; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organophosphonates; Protein Folding; Pyridines; Pyrimidines; Signal Transduction; Thrombospondin 1

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adaptor Proteins, Signal Transducing; Amides; Animals; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Adhesion Molecules, Neuron-Glia; Cell Cycle Proteins; Cell Shape; Cells, Cultured; Mice; Mice, Inbred Strains; Mice, Knockout; Myosin Light Chains; Peptides, Cyclic; Phosphorylation; Platelet Activation; Pyridines; Pyrimidines; Receptors, Thrombin; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; src-Family Kinases; Trypsin