y 27632 has been researched along with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide in 9 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide) | Trials (4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide) | Recent Studies (post-2010) (4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 552 | 0 | 406 |
| Protein | Taxonomy | y 27632 (IC50) | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide (IC50) |
|---|---|---|---|
| TGF-beta receptor type-1 | Homo sapiens (human) | 0.2587 | |
| TGF-beta receptor type-2 | Homo sapiens (human) | 0.066 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Imaizumi, M; Itoh, Y; Kimoto, K; Nakatsuka, K | 1 |
| Danjyo, T; Hirami, Y; Ikeda, H; Jin, ZB; Osakada, F; Sasai, Y; Takahashi, M; Watanabe, K | 1 |
| Abo, Y; Ichikawa, H; Nakata, N; Sasaki, K; Shirasawa, S; Tomotsune, D; Yokoyama, T; Yoshie, S; Yue, F | 1 |
| Ge, J; Jia, J; Li, L; Sun, A; Wang, K; Wang, S; Zhao, G; Zou, Y | 1 |
| Aly, H; Grossenheider, TC; Marshall, CA; Matkovich, SJ; McDaniel, ML; Miyoshi, H; Rohatgi, N; Stappenbeck, TS | 1 |
| Amornpisutt, R; Issaragrisil, S; Kheolamai, P; Klincumhom, N; Laowtammathron, C; Lorthongpanich, C; Potirat, P; Poungvarin, N; U-pratya, Y; Wattanapanitch, M | 1 |
| Duan, E; Feng, S; Han, M; Jiang, E; Lei, X; Liu, C; Ru, Y; Ruan, X; Shi, L; Su, P; Wang, H; Xu, Y; Yang, Y; Zhou, J | 1 |
| Idiris, A; Kumagai, H; Miyagi, Y; Miyazaki, K; Okamoto, R; Togo, S | 1 |
9 other study(ies) available for y 27632 and 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
Topics: Amides; Benzamides; Cell Line; Collagen Type I; Depression, Chemical; Dioxoles; Enzyme Inhibitors; Epithelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Pigment Epithelium of Eye; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Transfection; Transforming Growth Factor beta2 | 2007 |
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.
Topics: Amides; Animals; Benzamides; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Dioxoles; Gene Expression; Humans; Isoquinolines; Kruppel-Like Factor 4; Mice; Pluripotent Stem Cells; Protein Kinase Inhibitors; Pyridines; Retina | 2009 |
Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells.
Topics: Amides; Apoptosis; Benzamides; Caspase 10; Caspase 3; Caspase 8; Cell Line; Cell Survival; Cryopreservation; Cryoprotective Agents; Dioxoles; Embryonic Stem Cells; Humans; Imidazoles; Interleukin-1beta; p38 Mitogen-Activated Protein Kinases; Pyridines; rho-Associated Kinases; Transforming Growth Factor beta | 2012 |
Up-regulation of BMP-2 antagonizes TGF-β1/ROCK-enhanced cardiac fibrotic signalling through activation of Smurf1/Smad6 complex.
Topics: Amides; Animals; Benzamides; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Dioxoles; Fibrosis; Gene Knockdown Techniques; Heart; Immunoprecipitation; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C-delta; Pyridines; rho-Associated Kinases; Sequence Analysis, RNA; Signal Transduction; Smad6 Protein; Transforming Growth Factor beta1; Ubiquitin-Protein Ligases; Up-Regulation | 2012 |
A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype.
Topics: Adult; Amides; Benzamides; beta Catenin; Carrier Proteins; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Culture Media, Conditioned; Dioxoles; Gene Expression Profiling; Humans; Insulin-Secreting Cells; Pyridines; Receptor Cross-Talk; rho-Associated Kinases; Thrombospondins; Wnt Signaling Pathway; Wnt3A Protein | 2013 |
Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages.
Topics: Amides; Benzamides; Biomarkers; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Dermis; Dioxoles; Fibroblasts; Gene Expression; Histone Deacetylases; Humans; Induced Pluripotent Stem Cells; Karyotyping; Neural Stem Cells; Neurons; Pyridines; rho-Associated Kinases; Signal Transduction; Smad Proteins; Valproic Acid | 2014 |
Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.
Topics: Activins; Amides; Benzamides; Biomarkers; Blood Platelets; Cell Culture Techniques; Cell Separation; Cost-Benefit Analysis; Diffusion; Dioxoles; Equipment Design; Fetal Blood; High-Throughput Screening Assays; Humans; Intercellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Megakaryocytes; Oxygen; Pyridines; Rheology; Signal Transduction; Thrombopoiesis; Tretinoin; Weightlessness Simulation | 2016 |
Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix.
Topics: A549 Cells; Adenocarcinoma; Amides; Benzamides; Cancer-Associated Fibroblasts; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; Collagen; Colonic Neoplasms; Connective Tissue; Dioxoles; Epidermal Growth Factor; Fibroblasts; Fibronectins; Humans; Immunohistochemistry; Integrin alpha5beta1; MCF-7 Cells; Morpholines; Neoplasm Invasiveness; Pyridines; Spheroids, Cellular; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2020 |