y 27632 has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 33 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) | Trials (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) | Recent Studies (post-2010) (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 2,577 | 27 | 327 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 21 (63.64) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, X; Gong, MC; Jia, T; Somlyo, AP; Somlyo, AV | 1 |
| Aepfelbacher, M; Bauer, M; Essler, M; Maschberger, P; Retzer, M; Siess, W; Watson, SP; Wilde, JI | 1 |
| Nobe, K; Paul, RJ | 1 |
| Asbóth, G; López, BA; Moore, F | 1 |
| Hartshorne, DJ; Isaka, N; Ito, M; Kureishi, Y; Moriki, N; Nakano, T; Okamoto, R; Onishi, K; Seko, T | 1 |
| Hosaka, K; Mizuno, R; Ohhashi, T | 1 |
| Bauer, J; Parekh, N | 1 |
| Hirano, K; Kanaide, H; Maeda, Y; Nishimura, J; Sasaki, T | 2 |
| Brett, SE; Luykenaar, KD; Welsh, DG; Wiehler, WB; Wu, BN | 1 |
| Didion, SP; Faraci, FM; Mathur, S; Ryan, MJ; Sigmund, CD | 1 |
| Jiang, MJ; Tsai, MH | 2 |
| Cogolludo, A; Lodi, F; Moreno, L; Perez-Vizcaino, F; Tamargo, J | 1 |
| Eto, M; Gong, MC; Guo, Z; Pang, H; Su, W; Xie, Z | 1 |
| Jiang, SZ; Li, ZL; Wang, DS; Wang, HJ; Yuan, M | 1 |
| Lonigro, AJ; Losapio, JL; Sprague, RS; Stephenson, AH | 1 |
| Hester, RL; Naik, JS; Xiang, L | 1 |
| Shimoda, LA; Sylvester, JT; Weigand, L | 1 |
| Berton, G; Cattaneo, M; Cavallini, C; Degan, M; Fumagalli, L; Gaino, S; Lecchi, A; Lechi Santonastaso, C; Minuz, P; Tommasoli, RM | 1 |
| Johnson, GJ; Krumwiede, MD; Leis, LA; White, JG | 1 |
| Che, M; Chen, Y; Guo, Y; Honn, KV; Nie, D; Qiao, Y; Tang, Y; Wang, MT; Yang, D; Zacharek, A | 1 |
| Honjo, H; Ito, S; Kamiya, K; Kume, H; Makino, Y; Oguma, T; Shimokata, K; Shiraki, A | 1 |
| Beitinger, F; Bilzer, M; Gerbes, AL; Göke, B; Gülberg, V; Härtl, JM; Steib, CJ | 1 |
| Chesler, NC; Tabima, DM | 1 |
| Fang, Y; Li, T; Liu, L; Xu, J; Yang, G; Zhu, Y | 1 |
| Andersson, KE; Gratzke, C; Hartmann, AC; Hedlund, P; Hennenberg, M; Schlenker, B; Steib, CJ; Stief, CG; Strittmatter, F; Weinhold, P | 1 |
| Aalkjaer, C; Brøndum, E; Flyvbjerg, A; Kold-Petersen, H; Nilsson, H | 1 |
| Goulopoulou, S; Hannan, JL; Matsumoto, T; Webb, RC | 1 |
| Chang, X; Cui, YC; Fan, JY; Han, JY; He, K; Hu, BH; Li, Q; Liu, YY; Mao, XW; Pan, CS; Sun, K; Yan, L | 1 |
| Doi, T; Enomoto, Y; Iida, H; Iida, Y; Iwama, T; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Ogura, S; Otsuka, T; Tanabe, K; Tokuda, H; Tsujimoto, M; Yamamoto, N | 1 |
| Demyanets, S; Hohensinner, PJ; Huber, K; Kaun, C; Krychtiuk, KA; Lenz, M; Pentz, R; Stojkovic, S; Thaler, B; Wojta, J; Zuckermann, A | 1 |
| Gaynullina, DK; Selivanova, EK; Shilova, LD; Shvetsova, AA; Tarasova, OS | 1 |
33 other study(ies) available for y 27632 and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
| Article | Year |
|---|---|
The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Arachidonic Acid; Calcium; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Octoxynol; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rabbits; rho-Associated Kinases; Type C Phospholipases | 1998 |
Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Blood Platelets; Calcium; Cell Size; Enzyme Inhibitors; GTP-Binding Proteins; Hemostatics; Humans; Ligands; Membrane Proteins; Myosin Light Chains; Phosphorylation; Pyridines; Receptors, Thrombin; rhoB GTP-Binding Protein; Thrombin; Vasoconstrictor Agents | 1999 |
Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Intracellular Fluid; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sarcoplasmic Reticulum; Signal Transduction; Stress, Mechanical; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Thromboxane receptor signalling in human myometrial cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Caspase 3; Caspase Inhibitors; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Myometrium; Oligopeptides; Protein Isoforms; Protein Serine-Threonine Kinases; Pyridines; Receptors, Thromboxane; rho-Associated Kinases; Signal Transduction; Type C Phospholipases | 2002 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Rho-Rho kinase pathway is involved in the regulation of myogenic tone and pump activity in isolated lymph vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Lymphatic System; Male; Muscle Tonus; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Okadaic Acid; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; Vasoconstrictor Agents | 2003 |
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents | 2003 |
Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Amides; Animals; Calcium; Cattle; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Middle Cerebral Artery; Myosins; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Vasoconstriction | 2003 |
Pyrimidine nucleotides suppress KDR currents and depolarize rat cerebral arteries by activating Rho kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Cerebral Arteries; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; rho-Associated Kinases; Uridine Triphosphate; Vasoconstrictor Agents | 2004 |
Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Amides; Angiotensin II; Animals; Aorta; Carotid Arteries; Infusion Pumps, Implantable; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitroprusside; Papaverine; Phenylephrine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Sequence Deletion; Serotonin; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Ascorbic Acid; Bradykinin; Cattle; Cerebral Arteries; Chromones; Culture Media; Culture Media, Serum-Free; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Genistein; Imidazoles; In Vitro Techniques; Indoles; Maleimides; Morpholines; Oxidative Stress; Potassium; Protein Kinase Inhibitors; Pyridines; Serum; Superoxide Dismutase; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2004 |
Extracellular signal-regulated kinase1/2 in contraction of vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Butadienes; Calcium; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Genistein; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Nitriles; Phenylephrine; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley | 2005 |
Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Aging; Amides; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endothelium, Vascular; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Protein Kinase C; Pulmonary Artery; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Swine; Thromboxane A2 | 2005 |
RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Immunoblotting; Indoles; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Thrombin; Vasoconstrictor Agents | 2005 |
[Role of ROK in contraction of rat femoral arteries after 14 d tail suspension].
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Body Weight; Femoral Artery; Hindlimb Suspension; Intracellular Signaling Peptides and Proteins; Male; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents; Weightlessness Simulation | 2004 |
5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Amides; Animals; Calcium Chloride; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Myosin Light Chains; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rabbits; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic Agents; Aging; Amides; Animals; Arteries; Calcium Signaling; Gene Expression Regulation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Zucker; rho-Associated Kinases; rhoA GTP-Binding Protein; Thinness; Vasoconstriction | 2006 |
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction | 2006 |
Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Amides; Apyrase; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Humans; Integrin alpha2; Intracellular Signaling Peptides and Proteins; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Purinergic P2; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Signal Transduction; Tyrosine | 2006 |
Rho-kinase-mediated regulation of receptor-agonist-stimulated smooth muscle contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Amides; Animals; Arteries; Carrier Proteins; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Molecular Sequence Data; Muscle Proteins; Muscle, Smooth, Vascular; Myosin Light Chains; Phenylephrine; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Threonine; Vasoconstrictor Agents | 2006 |
The critical role of myosin IIA in platelet internal contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Adult; Amides; Blood Platelets; Cell Shape; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Microscopy, Electron, Transmission; Myosin Light Chains; Nonmuscle Myosin Type IIA; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases | 2007 |
Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydrazines; Ligands; Male; Prostatic Neoplasms; Pyridines; Receptors, Thromboxane A2, Prostaglandin H2; rhoA GTP-Binding Protein | 2008 |
Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Bridged-Ring Compounds; Calcium Channel Blockers; Calcium Signaling; Diltiazem; Dinoprost; Dioxanes; Enzyme Inhibitors; Estrenes; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Male; Maleimides; Muscle Contraction; Muscle, Smooth; Norbornanes; Pyridines; Pyrrolidinones; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Signal Transduction; Thiocarbamates; Thiones; Trachea; Type C Phospholipases; Vasoconstrictor Agents; Verapamil | 2009 |
Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Gadolinium; Hydrogen Peroxide; Kupffer Cells; Liver Cirrhosis; Male; Microfilament Proteins; Portal Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfonamides; Xanthine; Xanthine Oxidase | 2010 |
The effects of vasoactivity and hypoxic pulmonary hypertension on extralobar pulmonary artery biomechanics.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Biomechanical Phenomena; Cell Hypoxia; Hypertension, Pulmonary; Male; Mice; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2010 |
The mechanism by which RhoA regulates vascular reactivity after hemorrhagic shock in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Cell Hypoxia; Cells, Cultured; Disease Models, Animal; Female; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Norepinephrine; p21-Activated Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyridines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Shock, Hemorrhagic; Signal Transduction; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Thromboxane A2 induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Amides; Calcium; Calmodulin; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Immunohistochemistry; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Prostate; Pyridines; Receptors, Thromboxane A2, Prostaglandin H2; rho-Associated Kinases; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents | 2011 |
Impaired myogenic tone in isolated cerebral and coronary resistance arteries from the goto-kakizaki rat model of type 2 diabetes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Blood Glucose; Calcium; Coronary Vessels; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Middle Cerebral Artery; Nitric Oxide; Protein Kinase C; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases | 2012 |
Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Enzyme Inhibitors; Female; Indoles; Maleimides; Mesenteric Arteries; Pregnancy; Pregnancy, Animal; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; rho-Associated Kinases; Signal Transduction; Uterine Artery; Uterus; Vasoconstrictor Agents | 2012 |
ROCK-dependent ATP5D modulation contributes to the protection of notoginsenoside NR1 against ischemia-reperfusion-induced myocardial injury.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Adenosine Triphosphate; Amides; Animals; Apoptosis; Cardiotonic Agents; Cell Culture Techniques; Cell Hypoxia; Enzyme Inhibitors; Ginsenosides; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myofibrils; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2014 |
Rho-kinase regulates human platelet activation induced by thromboxane A2 independently of p38 MAP kinase.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Depolymerizing Factors; Amides; Blood Platelets; Enzyme Inhibitors; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Pyridines; rho-Associated Kinases; Signal Transduction; Thromboxane A2 | 2015 |
Cardioprotective cytokine interleukin-33 is up-regulated by statins in human cardiac tissue.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cyclohexenes; Cytokines; Diphosphonates; Fibroblasts; Fluvastatin; Gene Expression Regulation; Heart; Heart Diseases; Humans; Interleukin-33; Lovastatin; Mevalonic Acid; Monoterpenes; Myocardium; Myocytes, Cardiac; Pravastatin; Pyridines; rhoA GTP-Binding Protein; Simvastatin; Thiazolidines | 2018 |
Intrauterine growth restriction weakens anticontractile influence of NO in coronary arteries of adult rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Coronary Vessels; Disease Models, Animal; Female; Fetal Growth Retardation; Male; Mesenteric Arteries; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase Type III; Pregnancy; Pyridines; Rats, Wistar; rho-Associated Kinases | 2021 |