Page last updated: 2024-08-16

xylometazoline and oxymetazoline

xylometazoline has been researched along with oxymetazoline in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (22.58)	18.7374
1990's	14 (45.16)	18.2507
2000's	5 (16.13)	29.6817
2010's	5 (16.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
de Jong, AP; van Dam, H	1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B	1
Esbenshade, TA; Han, C; Hollinger, S; Minneman, KP; Theroux, TL	1
Dukat, M; Glennon, RA; Kamboj, R; Law, H; Lee, DK; Mazzocco, L; Prisinzano, T; Rampersad, V; Teitler, M	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Fredriksson, H; Månsson, I	1
Baretti, R; Bognar, IT; Fischer, S; Fuder, H; Veldet, C	1
Clement, PA; Maes, JJ	1
Håkansson, B; Linder, C; Ohlsson, K; Tegner, H; Toremalm, NG	1
Forsgren, A; Håkansson, B; Tegner, H; Toremalm, NG	1
Aust, R; Ekedahl, C; Geterud, A; Odkvist, L; Petruson, B	2
Hofmann, T; Koidl, B; Wolf, G	1
Deitmer, T; Scheffler, R	1
Berg, OH; Lie, K; Steinsvåg, SK	1
Wilhelmson, B	1
Li Wan Po, A; Su, XY	1
Bast, A; Dekker, I; Griffioen, DH; Scheeren, RA; Voss, HP; Westerveld, GJ	1
Graf, P	1
Ivarsson, A; Jessen, M; Malm, L	1
Boek, WM; Graamans, K; Huizing, EH; Merkus, FW; Romeijn, SG; Verhoef, JC	1
Isacson, D; Lundberg, L	1
Bast, A; de Haan-Koelewijn, GJ; den Hartog, GJ; Scheeren, RA; van der Hee, RM; Voss, HP; Westerveld, GJ	1
Dorn, M; Hofmann, W; Knick, E	1
Bloching, M; Holzhausen, HJ; Knipping, S; Riederer, A	1
Mickenhagen, A; Neugebauer, P; Siefer, O; Stennert, E	1
Bönisch, H; Bootz, F; Haenisch, B; Herberhold, S; Ramseger, R; Tschaikin, M; Walstab, J	1
Eskiizmir, G; Hirçin, Z; Ozyurt, B; Unlü, H	1
Bielenberg, J	1
Abo El Abass Mohamed, S; Belal, F; Elmansi, H; Fathy, ME	1
De Sutter, AI; Deckx, L; Guo, L; Mir, NA; van Driel, ML	1

Reviews

1 review(s) available for xylometazoline and oxymetazoline

Article	Year
Nasal decongestants in monotherapy for the common cold. The Cochrane database of systematic reviews, 2016, Oct-17, Volume: 10 Topics: Administration, Intranasal; Adult; Child; Common Cold; Humans; Imidazoles; Nasal Decongestants; Oxymetazoline; Phenylpropanolamine; Pseudoephedrine; Randomized Controlled Trials as Topic; Time Factors	2016

Trials

7 trial(s) available for xylometazoline and oxymetazoline

Article	Year
[Which nasal spray is preferred by patients?]. Lakartidningen, 1991, Feb-06, Volume: 88, Issue:6 Topics: Adolescent; Adult; Aerosols; Aged; Child; Drug Evaluation; Female; Humans; Imidazoles; Male; Middle Aged; Nasal Decongestants; Nasal Obstruction; Oxymetazoline; Prospective Studies	1991
The usefulness of irrigation of the maxillary sinus in children with maxillary sinusitis on the basis of the Water's X-ray. Rhinology, 1987, Volume: 25, Issue:4 Topics: Anti-Bacterial Agents; Child; Child, Preschool; Combined Modality Therapy; Humans; Imidazoles; Maxillary Sinus; Nasal Decongestants; Oxymetazoline; Radiography; Sinusitis; Therapeutic Irrigation	1987
A comparative preference study between xylometazoline nasal dose spray (Otrivin) and oxymetazoline single-dose pipettes (Nezeril). Rhinology, 1983, Volume: 21, Issue:3 Topics: Adult; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Nasal Decongestants; Oxymetazoline; Random Allocation; Rhinitis	1983
[Comparison between xylometazoline in a dosage spray and oxymetazoline in one dose pipettes]. Lakartidningen, 1983, May-04, Volume: 80, Issue:18 Topics: Adult; Aerosols; Clinical Trials as Topic; Female; Humans; Imidazoles; Male; Middle Aged; Oxymetazoline; Rhinitis	1983
Long-term use of oxy- and xylometazoline nasal sprays induces rebound swelling, tolerance, and nasal hyperreactivity. Rhinology, 1996, Volume: 34, Issue:1 Topics: Administration, Intranasal; Adult; Benzalkonium Compounds; Double-Blind Method; Drug Tolerance; Female; Humans; Imidazoles; Male; Nasal Decongestants; Nasal Mucosa; Nasal Obstruction; Oxymetazoline; Preservatives, Pharmaceutical; Rhinitis; Time Factors	1996
[Tolerance and effectiveness of oxymetazoline and xylometazoline in treatment of acute rhinitis]. HNO, 2003, Volume: 51, Issue:10 Topics: Acute Disease; Administration, Intranasal; Adult; Aerosols; Benzalkonium Compounds; Common Cold; Double-Blind Method; Drug Hypersensitivity; Humans; Imidazoles; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Preservatives, Pharmaceutical; Rhinitis	2003
A comparative analysis of the decongestive effect of oxymetazoline and xylometazoline in healthy subjects. European journal of clinical pharmacology, 2011, Volume: 67, Issue:1 Topics: Administration, Intranasal; Adult; Female; Humans; Imidazoles; Male; Nasal Cavity; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Rhinitis, Vasomotor; Rhinomanometry; Rhinometry, Acoustic; Young Adult	2011

Other Studies

23 other study(ies) available for xylometazoline and oxymetazoline

Article	Year
Ultraviolet photoelectron spectroscopy of cyclic amidines. 1. Electronic structure of some alpha-adrenergic benzylimidazolines. Journal of medicinal chemistry, 1979, Volume: 22, Issue:11 Topics: Adrenergic alpha-Agonists; Chemical Phenomena; Chemistry; Imidazoles; Naphazoline; Oxymetazoline; Quantum Theory; Spectrophotometry, Ultraviolet; Structure-Activity Relationship	1979
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists. Journal of medicinal chemistry, 1984, Volume: 27, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction	1984
Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Molecular pharmacology, 1994, Volume: 46, Issue:5 Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Binding, Competitive; Catecholamines; Cattle; Cell Line; Cloning, Molecular; Cricetinae; Humans; Imidazoles; Inositol Phosphates; Phenethylamines; Phenoxybenzamine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Tetralones	1994
Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation. Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13 Topics: Adrenergic alpha-Agonists; Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; In Vitro Techniques; Isometric Contraction; Ligands; Male; Muscle, Smooth, Vascular; Oxymetazoline; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha; Receptors, Serotonin; Saphenous Vein; Serotonin Receptor Agonists; Structure-Activity Relationship	1998
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Alpha-adrenoceptor mediated facilitation of acetylcholine release in the rat perfused heart. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Catecholamines; Choline; Dopamine Agents; Electric Stimulation; Heart; Imidazoles; Imidazolines; Male; Myocardium; Neural Conduction; Oxymetazoline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vagus Nerve	1990
The inhibition of granulocyte phagocytosis by various components of nasal drops. Pharmacology & toxicology, 1989, Volume: 65, Issue:2 Topics: Administration, Intranasal; Benzalkonium Compounds; Granulocytes; Humans; Imidazoles; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Phagocytosis; Pharmaceutic Aids; Preservatives, Pharmaceutical; Thimerosal	1989
Inhibitory effects of nasal drops components on granulocyte chemotaxis. Pharmacology & toxicology, 1989, Volume: 64, Issue:4 Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Benzalkonium Compounds; Chemotaxis; Granulocytes; Humans; Imidazoles; In Vitro Techniques; Oxymetazoline; Thimerosal	1989
[In vitro studies of the effect of vasoconstrictor nose drops on ciliary epithelium of human nasal mucosa]. Laryngo- rhino- otologie, 1995, Volume: 74, Issue:9 Topics: Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Mucociliary Clearance; Naphazoline; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Phenylephrine	1995
The effect of different preparations of nasal decongestants on ciliary beat frequency in vitro. Rhinology, 1993, Volume: 31, Issue:4 Topics: Cells, Cultured; Cilia; Humans; Imidazoles; In Vitro Techniques; Mucociliary Clearance; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Preservatives, Pharmaceutical	1993
The effect of decongestive nosedrops on human respiratory mucosa in vitro. The Laryngoscope, 1994, Volume: 104, Issue:9 Topics: Adenoids; Benzalkonium Compounds; Cell Membrane; Cell Survival; Cilia; Culture Techniques; Desmosomes; Epithelium; Humans; Imidazoles; Microscopy, Electron; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Microvilli; Nasal Decongestants; Nasal Mucosa; Nuclear Envelope; Oxymetazoline; Preservatives, Pharmaceutical	1994
[Rhinitis medicamentosa, an increasing problem. Do nose drops adversely affect bacterial infections?]. Lakartidningen, 1994, Dec-07, Volume: 91, Issue:49 Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Humans; Imidazoles; Oxymetazoline; Rhinitis	1994
The effect of some commercially available antihistamine and decongestant intra-nasal formulations on ciliary beat frequency. Journal of clinical pharmacy and therapeutics, 1993, Volume: 18, Issue:3 Topics: Animals; Cilia; Ephedrine; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Male; Oxymetazoline; Phthalazines; Rats; Rats, Wistar; Trachea	1993
Anti-oxidant actions of oxymethazoline and xylomethazoline. European journal of pharmacology, 1995, Sep-15, Volume: 291, Issue:1 Topics: Animals; Antioxidants; Cimetidine; Free Radical Scavengers; Histamine H2 Antagonists; Hydroxyl Radical; Imidazoles; In Vitro Techniques; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; Oxymetazoline; Rats; Rats, Wistar; Reactive Oxygen Species	1995
Nasal airway resistance after decongestion with a nasal spray or a bellows device. Rhinology, 1996, Volume: 34, Issue:1 Topics: Administration, Intranasal; Adult; Airway Resistance; Female; Humans; Imidazoles; Male; Manometry; Middle Aged; Nasal Decongestants; Nasal Obstruction; Nebulizers and Vaporizers; Oxymetazoline; Reproducibility of Results; Time Factors	1996
Validation of animal experiments on ciliary function in vitro. I. The influence of substances used clinically. Acta oto-laryngologica, 1999, Volume: 119, Issue:1 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Chick Embryo; Cocaine; Cryopreservation; Humans; Hydrogen-Ion Concentration; Imidazoles; Lidocaine; Mucociliary Clearance; Mucous Membrane; Nasal Decongestants; Oxymetazoline; Propranolol; Trachea	1999
The impact of over-the-counter availability of nasal sprays on sales, prescribing, and physician visits. Scandinavian journal of primary health care, 1999, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Prescriptions; Female; Health Expenditures; Health Services; Humans; Imidazoles; Infant; Infant, Newborn; Male; Middle Aged; Nasal Decongestants; Nebulizers and Vaporizers; Nonprescription Drugs; Oxymetazoline; Retrospective Studies; Rhinitis; Sinusitis; Sweden	1999
Inhibition of nitric oxide synthase by nasal decongestants. The European respiratory journal, 2000, Volume: 16, Issue:3 Topics: Animals; Cell Line; Citrulline; Enzyme Induction; Imidazoles; In Vitro Techniques; Lipopolysaccharides; Macrophages, Alveolar; Nasal Decongestants; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxymetazoline; Rats	2000
[Ultrastructural changes in human nasal mucosa in rhinitis medicamentosa]. HNO, 2006, Volume: 54, Issue:10 Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Capillary Permeability; Chronic Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Epithelial Cells; Humans; Imidazoles; Long-Term Care; Microscopy, Electron; Mucociliary Clearance; Nasal Decongestants; Nasal Mucosa; Nasal Obstruction; Oxymetazoline; Rhinitis; Tachyphylaxis; Turbinates	2006
[The influence of different alpha-sympathomimetic drugs and benzalkoniumchlorid on the ciliary beat frequency of in vitro cultured human nasal mucosa cells]. Laryngo- rhino- otologie, 2008, Volume: 87, Issue:1 Topics: Adrenergic alpha-Agonists; Anti-Infective Agents, Local; Benzalkonium Compounds; Cilia; Dose-Response Relationship, Drug; Equipment Design; Fourier Analysis; Humans; Imidazoles; In Vitro Techniques; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Mucociliary Clearance; Naphazoline; Nasal Mucosa; Oxymetazoline; Signal Processing, Computer-Assisted; Software; Video Recording	2008
Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundamental & clinical pharmacology, 2010, Volume: 24, Issue:6 Topics: Adrenergic alpha-Agonists; Adult; Binding, Competitive; Female; HEK293 Cells; Humans; Imidazoles; Male; Nasal Mucosa; Oxymetazoline; Receptors, Adrenergic, alpha; RNA, Messenger	2010
["Of snakes and crocodiles": central side effects of nose drops and facts about rhinitis medicamentosa]. Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2011, Volume: 30, Issue:10 Topics: Administration, Intranasal; Adult; Child, Preschool; Drug Combinations; Female; Hallucinations; Humans; Imidazoles; Male; Nasal Decongestants; Oxymetazoline; Phenylephrine; Pseudoephedrine; Rhinitis; Sympathomimetics; Triprolidine	2011
Simultaneous Determination of Cromolyn Sodium Combined Dosage Forms Using Isocratic HPLC Method. Journal of chromatographic science, 2017, Volume: 55, Issue:1 Topics: Chromatography, High Pressure Liquid; Cromolyn Sodium; Drug Combinations; Imidazoles; Limit of Detection; Linear Models; Oxymetazoline; Reproducibility of Results	2017