Page last updated: 2024-08-16

xylazine and dexmedetomidine

xylazine has been researched along with dexmedetomidine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's0 (0.00)29.6817
2010's19 (61.29)24.3611
2020's11 (35.48)2.80

Authors

AuthorsStudies
Bonhaus, DW; Chang, LK; Chang, TK; Daunt, DA; Eglen, RM; Hsu, SA; Jasper, JR; Lesnick, JD; Yamanishi, SS1
Berry, K; Bouts, T; Gasthuys, F; Harrison, N; Routh, A; Taylor, P1
Chung, HW; Jung, KH; Lee, EJ; Lee, KH; Paik, JY; Park, JW1
Mikaelian, I; Singer, L; Wellington, D1
Janovyak, E; Lizarraga, I1
Hopster, K; Hopster-Iversen, C; Kästner, S; Müller, C; Rohn, K; Stahl, J1
Lien, CY; Wang, LC; Yu, JF1
Ito, S; Kobayashi, T; Otsuguro, K; Yamaguchi, S1
Drobatz, KJ; Thawley, VJ1
Clare, MC; Claypool, SP; Julius, TM; Willey, JL1
Alcorn, J; Benmansour, P; Billinsky, J; Duke-Novakovski, T1
Boccardo, A; Cagnardi, P; Capolongo, F; Di Cesare, F; Lucatello, L; Pravettoni, D; Ravasio, G; Villa, R1
Aristizabal, F; Cenani, A; Guedes, AGP; Nieto, J; Tearney, CC1
Buratta, S; Chiaradia, E; Ferrara, G; Mancini, F; Nannarone, S; Pistilli, A; Santinelli, I; Stabile, AM; Vuerich, M1
Cavilla, V; Del Sole, MJ; Moreno, L; Nejamkin, P; Schaiquevich, P1
Barnett, GJ; Barnett, IJ; Smith, PC; Wilson, SR1
Geburek, F; Hopster, K; Hopster-Iversen, C; Kästner, SBR; Wittenberg-Voges, L1
Hopster, K; Kästner, SB; Raekallio, M; Rohn, K; Vainio, OM; Wittenberg-Voges, L1
Abraham, AM; Aguirre, JI; Castillo, EJ; Grove, K; Jiron, JM; Malinowski, C; Malphurs, WL; Mendieta Calle, JL; Messer, JG; Reznikov, LR; Zubcevic, J1
Downs, JC; Girkin, CA; Jasien, JV1
Ayer, IM; Cardoso, CG; Honsho, CS; Jorge, AT; Mattos-Junior, E1
Abouelnasr, KS; El-Khodery, SA; Eltayesh, RA; Hamed, MA; Ibrahim, HMM1
Hikasa, Y; Matsukawa, T1
Azari, O; Ebrahimpour, F; Molaei, MM; Samimi, AS1
Allweiler, S; Almeida, DC; Baldo, CF; Guedes, A; Knych, H; Tucker, L; Wendt-Hornickle, E1
Im, GH; Kim, SG; You, T1
Azari, O; Ebrahimzadeh, F; Mashayekhi, H; Molaei, MM; Nahvi, A; Samimi, AS1
Aghamiri, SM; Hajian, M; Oroumieh, A; Samimi, AM; Samimi, AS1
Ağar, E; Al-Gailani, L; Al-Kaleel, A; Arslan, G; Ayyıldız, M1
Han, X; Koutsogiannaki, S; Maisat, W; Soriano, SG; Yuki, K1
Akaraphutiporn, E; Bunnag, N; Durongphongtorn, S; Pacharinsak, C; Sharp, P; Soontornvipart, K; Wangdee, C1

Trials

13 trial(s) available for xylazine and dexmedetomidine

ArticleYear
Comparison of the mechanical hypoalgesic effects of five α2-adrenoceptor agonists in donkeys.
    The Veterinary record, 2013, Sep-28, Volume: 173, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Anesthesia, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Equidae; Imidazoles; Medetomidine; Pain Threshold; Time Factors; Xylazine

2013
Effects of dexmedetomidine and xylazine on cardiovascular function during total intravenous anaesthesia with midazolam and ketamine and recovery quality and duration in horses.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:1

    Topics: Anesthesia Recovery Period; Anesthetics, Dissociative; Animals; Blood Pressure; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Heart Rate; Horses; Hypnotics and Sedatives; Ketamine; Midazolam; Time Factors; Xylazine

2014
Comparison of xylazine-ketamine and dexmedetomidine-ketamine anesthesia in captive Formosan serows (Capricornis swinhoei).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2014, Volume: 45, Issue:4

    Topics: Anesthesia; Anesthetics, Dissociative; Animals; Animals, Zoo; Dexmedetomidine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Ketamine; Male; Ruminants; Xylazine

2014
Blood concentrations of remifentanil during and after infusion in horses anesthetized with isoflurane and dexmedetomidine.
    Research in veterinary science, 2016, Volume: 107

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Dexmedetomidine; Diazepam; Drug Interactions; Female; Half-Life; Horses; Isoflurane; Ketamine; Male; Piperidines; Remifentanil; Xylazine

2016
Comparison between the effects of postanesthetic xylazine and dexmedetomidine on characteristics of recovery from sevoflurane anesthesia in horses.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:2

    Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Horses; Isoflurane; Male; Methyl Ethers; Sevoflurane; Xylazine

2017
Comparison of 6 Injectable Anesthetic Regimens and Isoflurane in Gray Short-tailed Opossums (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2017, Sep-01, Volume: 56, Issue:5

    Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Ketamine; Monodelphis; Oxygen; Xylazine

2017
Effect of dexmedetomidine and xylazine followed by MK-467 on gastrointestinal microperfusion in anaesthetized horses.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Combined; Animals; Dexmedetomidine; Female; Gastrointestinal Tract; Horses; Isoflurane; Male; Microcirculation; Oxygen; Prospective Studies; Quinolizines; Xylazine

2018
Comparison of Isoflurane, Ketamine-Dexmedetomidine, and Ketamine-Xylazine for General Anesthesia during Oral Procedures in Rice Rats (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2019, 01-01, Volume: 58, Issue:1

    Topics: Anesthesia, General; Anesthetics; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Isoflurane; Ketamine; Laboratory Animal Science; Male; Mouth; Rats; Sigmodontinae; Xylazine

2019
Comparative Effect of Epidural Administration of Xylazine or Dexmedetomidine on Echocardiographic Dimensions and Cardiac Indices in Clinically Healthy Donkeys (Equus asinus).
    Journal of equine veterinary science, 2020, Volume: 85

    Topics: Animals; Dexmedetomidine; Echocardiography; Epidural Space; Equidae; Prospective Studies; Xylazine

2020
Comparative evaluation of sedative and clinical effects of dexmedetomidine and xylazine in dromedary calves (Camelus dromedarius).
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:2

    Topics: Animals; Camelus; Cross-Over Studies; Dexmedetomidine; Hypnotics and Sedatives; Male; Xylazine

2020
Pharmacokinetics and clinical effects of xylazine and dexmedetomidine in horses recovering from isoflurane anesthesia.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:4

    Topics: Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dexmedetomidine; Female; Horses; Hypnotics and Sedatives; Isoflurane; Male; Xylazine

2020
Effect of xylazine, detomidine, medetomidine and dexmedetomidine during laparoscopic SCNT embryo transfer on pregnancy rate and some physiological variables in goats.
    BMC veterinary research, 2022, Mar-15, Volume: 18, Issue:1

    Topics: Animals; Dexmedetomidine; Embryo Transfer; Female; Goats; Imidazoles; Laparoscopy; Medetomidine; Pregnancy; Pregnancy Rate; Prospective Studies; Xylazine

2022
Assessment of a Combination of Tiletamine/Zolazepam, Ketamine, and Dexmedetomidine for Anesthesia of Swine (Sus domesticus).
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2023, Sep-01, Volume: 62, Issue:5

    Topics: Anesthesia, General; Animals; Dexmedetomidine; Drug Combinations; Heart Rate; Ketamine; Male; Swine; Tiletamine; Xylazine; Zolazepam

2023

Other Studies

18 other study(ies) available for xylazine and dexmedetomidine

ArticleYear
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding.
    Biochemical pharmacology, 1998, Apr-01, Volume: 55, Issue:7

    Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cyclic AMP; Genetic Vectors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Protein Binding; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Proteins

1998
Comparison of three anaesthetic protocols in Bennett's wallabies (Macropus rufogriseus).
    Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Animals; Blood Gas Analysis; Body Temperature; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Imidazoles; Injections, Intramuscular; Ketamine; Macropodidae; Male; Medetomidine; Respiratory Rate; Xylazine

2010
α2-Adrenergic agonists including xylazine and dexmedetomidine inhibit norepinephrine transporter function in SK-N-SH cells.
    Neuroscience letters, 2013, Apr-29, Volume: 541

    Topics: 3-Iodobenzylguanidine; Adrenergic alpha-2 Receptor Agonists; Cell Line, Tumor; Dexmedetomidine; Fluoxetine; Humans; Iodine Radioisotopes; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Receptors, Adrenergic, alpha-2; Xylazine

2013
Comparison of ketamine-xylazine and ketamine-dexmedetomidine anesthesia and intraperitoneal tolerance in rats.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2013, Volume: 52, Issue:4

    Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Drug Therapy, Combination; Heart Rate; Imidazoles; Injections, Intraperitoneal; Ketamine; Male; Rats; Rats, Wistar; Xylazine

2013
Contribution of α2A-adrenoceptor subtype to effect of dexmedetomidine and xylazine on spinal synaptic transmission of mice.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Animals, Newborn; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Male; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Spinal Cord; Synaptic Transmission; Time Factors; Xylazine

2015
Assessment of dexmedetomidine and other agents for emesis induction in cats: 43 cases (2009-2014).
    Journal of the American Veterinary Medical Association, 2015, Dec-15, Volume: 247, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cat Diseases; Cats; Dexmedetomidine; Emetics; Female; Foreign Bodies; Male; Poisoning; Retrospective Studies; Vomiting; Xylazine

2015
Evaluation and comparison of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats: 47 cases (2007-2013).
    Journal of the American Veterinary Medical Association, 2016, Apr-15, Volume: 248, Issue:8

    Topics: Animals; Cat Diseases; Cats; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Poisoning; Retrospective Studies; Vomiting; Xylazine

2016
Pharmacokinetics and sedative effects of dexmedetomidine in dairy calves.
    New Zealand veterinary journal, 2017, Volume: 65, Issue:1

    Topics: Animals; Animals, Newborn; Cattle; Conscious Sedation; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Male; Respiratory Rate; Xylazine

2017
Effects of xylazine and dexmedetomidine on equine articular chondrocytes in vitro.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cartilage, Articular; Cell Membrane; Cell Survival; Chondrocytes; Dexmedetomidine; Horses; In Vitro Techniques; Male; Prospective Studies; Tetrazolium Salts; Xylazine

2017
Comparison of two sedation protocols for short electroretinography in cats.
    Journal of feline medicine and surgery, 2018, Volume: 20, Issue:2

    Topics: Anesthesia; Animals; Cats; Dexmedetomidine; Electroretinography; Female; Hypnotics and Sedatives; Ketamine; Xylazine

2018
Effects of controlled hypoxemia or hypovolemia on global and intestinal oxygenation and perfusion in isoflurane anesthetized horses receiving an alpha-2-agonist infusion.
    BMC veterinary research, 2017, Nov-28, Volume: 13, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Heart Rate; Horses; Hypovolemia; Hypoxia; Intestinal Mucosa; Intestines; Isoflurane; Laser-Doppler Flowmetry; Male; Oxygen; Prospective Studies; Spectrophotometry; Xylazine

2017
Effect of Anesthesia on Intraocular Pressure Measured With Continuous Wireless Telemetry in Nonhuman Primates.
    Investigative ophthalmology & visual science, 2019, 09-03, Volume: 60, Issue:12

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Dexmedetomidine; Intraocular Pressure; Isoflurane; Ketamine; Macaca mulatta; Male; Telemetry; Tonometry, Ocular; Xylazine

2019
A comparative study of the cardiopulmonary and sedative effects of a single intramuscular dose of ketamine anesthetic combinations in rabbits.
    Research in veterinary science, 2020, Volume: 128

    Topics: Acepromazine; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Arterial Pressure; Cross-Over Studies; Dexmedetomidine; Drug Combinations; Heart Rate; Hypnotics and Sedatives; Hypoxia; Injections, Intramuscular; Ketamine; Male; Midazolam; Prospective Studies; Rabbits; Respiratory Rate; Xylazine

2020
Effects of imidazoline and nonimidazoline α-adrenoceptor agonists and antagonists, including xylazine, medetomidine, dexmedetomidine, yohimbine, and atipamezole, on aggregation of feline platelets.
    American journal of veterinary research, 2020, Volume: 81, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Platelets; Cats; Dexmedetomidine; Imidazoles; Imidazolines; Medetomidine; Xylazine; Yohimbine

2020
Characterization of brain-wide somatosensory BOLD fMRI in mice under dexmedetomidine/isoflurane and ketamine/xylazine.
    Scientific reports, 2021, 06-23, Volume: 11, Issue:1

    Topics: Anesthetics, Combined; Animals; Brain; Dexmedetomidine; Functional Neuroimaging; Infusions, Intravenous; Isoflurane; Ketamine; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Somatosensory Cortex; Xylazine

2021
Evaluation of the sedative and physiological effects of xylazine, detomidine, medetomidine and dexmedetomidine in goats.
    Veterinary medicine and science, 2022, Volume: 8, Issue:3

    Topics: Adrenergic Agonists; Animals; Dexmedetomidine; Goats; Hypnotics and Sedatives; Imidazoles; Medetomidine; Xylazine

2022
THE effect of general anesthetics on genetic absence epilepsy in WAG/Rij rats.
    Neurological research, 2022, Volume: 44, Issue:11

    Topics: Anesthetics; Anesthetics, General; Anesthetics, Intravenous; Animals; Chloral Hydrate; Dexmedetomidine; Epilepsy, Absence; Isoflurane; Ketamine; Male; Pentobarbital; Rats; Urethane; Xylazine

2022
Differential effects of dexmedetomidine on Gram-positive and Gram-negative bacterial killing and phagocytosis.
    International immunopharmacology, 2023, Volume: 120

    Topics: Anti-Bacterial Agents; Dexmedetomidine; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Phagocytosis; Reactive Oxygen Species; Toll-Like Receptor 4; Xylazine

2023