Page last updated: 2024-08-16

xylazine and detomidine

xylazine has been researched along with detomidine in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (20.00)	18.7374
1990's	22 (31.43)	18.2507
2000's	18 (25.71)	29.6817
2010's	9 (12.86)	24.3611
2020's	7 (10.00)	2.80

Authors

Authors	Studies
Clarke, KW; England, GC; Goossens, L	1
Benson, GJ; Branson, KR; Lin, HC; Olson, WA; Thurmon, JC; Tranquilli, WJ; Vähä-Vahe, AT	1
Partlo, LA; Sainsbury, RS	1
Ayoub, RS; Majeed, NH; Mohammad, FK	1
Ecker, GL; McKee, SL; Riddolls, LJ; Willoughby, RA	1
Hinchcliff, KW; Muir, WW; Wagner, AE	1
De Moor, A; Gasthuys, F; Parmentier, D	1
Garner, HE; Krause, GF; Sarazan, RD; Starke, WA	1
Nyman, L; Ruskoaho, H; Virtanen, R	1
Kärki, NT; Puurunen, J; Ruskoaho, H; Savola, JM	1
Allal, C; Ruckebusch, Y	1
Livingston, A; Nolan, A; Waterman, AE	1
Roger, T; Ruckebusch, Y	1
Nyman, L; Virtanen, R	1
MacDonald, E; Virtanen, R	1
Dougherty, J; Tobin, T; Weckman, T; Wood, T; Woods, WE	1
Deegen, E; Klein, HJ; Reitemeyer, H	1
Hilfiger, J; Lowe, JE	1
Kaisila, M; MacDonald, E; Virtanen, R	1
Virtanen, R	1
Mason, DE; Muir, WW	1
Benson, GJ; Lin, HC; Thurmon, JC; Tranquilli, WJ	1
Mama, KR; Pascoe, PJ; Steffey, EP	1
Castillo-Olivares, JL; Mascías, A; San Román, F; Santos, M; Segura, IA; Tendillo, FJ	1
Goossens, L; Jossfck, H; Schatzmann, U; Stauffer, JL	1
Muir, WW; Skarda, RT	1
Clarke, KW; England, GC	1
Baker, GJ; Brown, J; Fubini, S; Jochle, W; Lowe, JE; Moore, JN; Reeves, MJ; Watkins, JP; White, NA	1
Craigmill, AL; Damian, P; Rangel-Lugo, M; Riviere, JE	1
Harkins, JD; Mundy, GD; Queiroz-Neto, A; Tobin, T; West, D	1
Black, WD; Celly, CS; McDonell, WN; Young, SS	1
Burrow, JA; Hartless, CS; Merritt, AM	1
Clark, TP; Schwartz, DD	1
Kumar, A; Tiwari, SK; Vainio, O	1
Aguilar, JM; Galka, ME; Gómez-Villamandos, RJ; Quevedo, MA; Santisteban, JM	1
Hinchcliff, KW; Hubbell, JA; Muir, WW; Robertson, JT; Sams, RA; Schmall, LM	1
Grove, DM; Ramsay, EC	1
Badgley, B; Beard, W; Bothwell, V; Hubbell, JA; Lerche, P; Miller, T; Muir, WW; Robertson, JT	1
Futaok, S; Hamaguchi, H; Izumisawa, Y; Katoh, S; Kotani, T; Muir, WW; Seno, T; Tsubakishita, S; Ueda, I; Yamashita, K	1
Christley, RM; Cohen, ND; Love, S; Preston, T; Roussel, AJ; Sutton, DG	1
Eades, SC; Hosgood, GL; Moore, RM; Wooldridge, AA	2
Fuente, M; Garcia-Iturralde, R; Herran, R; Lopez-Sanroman, J; Santos, M; Tendillo, FJ	1
Bergström, U; Neil, A; Törneke, K	1
Doherr, MG; Lanz, F; Moens, Y; Schatzmann, U	1
Lin, HC; Riddell, MG	1
Garcia, AA; Nuñez, E; Ocampo, L; Rodriguez, A; Steffey, EP	1
Christina Haerdi-Landerer, M; Neiger-Aeschbacher, G; Schlegel, U	1
Eskandari, MH; Vesal, N	1
Vesal, N; Zare, P	1
Atalan, G; Cenesiz, M; Kaya, M; Onder, F; Uzun, M; Yildiz, S	1
Bufalari, A; Gialletti, R; Moriconi, F; Nannarone, S; Veschini, I	1
Araujo, RR; Ginther, OJ	1
Korpivaara, T; Rohrbach, H; Schatzmann, U; Spadavecchia, C	1
Auer, U; Beigelböck, C; Mosing, M; Wenger, S; Zenker, W	1
Bizon-Mercier, C; Couroucé-Malblanc, A; Deniau, V; Depecker, M	1
del Alamo, AM; Holmbak-Petersen, R; López-Sanromán, FJ; Santiago, I; Varela, M	1
Janovyak, E; Lizarraga, I	1
Fosgate, GT; Kullmann, A; Page, PC; Rioja, E; Sanz, M; Saulez, MN	1
Edner, A; Fahlman, Å; Foggin, C; Nyman, G; Wenger, S	1
Bertini, S; Colla, C; Menozzi, A; Placenza, G; Poli, E; Pozzoli, C	1
Bass, L; King, MR; Moorman, VJ	1
Canuto, LEF; Cavalero, TMS; Freitas-Dell'aqua, CP; Gobato, MLM; Papa, FO; Rodrigues, LT; Scheeren, VFC; Schmith, RA	1
Bass, L; Damone, J; Mama, K; Rao, S; Smith, MC	1
Bertin, FR; Hess, EK; Hodgson, JK; Kritchevsky, JE; Leschke, DHZ; Muir, GS	1
Brehm, W; Gittel, C; Hillmann, A; Michaele, A; Roth, S; Wippern, M	1
Chang, LJ; Ko, JC; Weil, AB; Weng, HY	1
Arnold, CE; Hatfield, R; Jarosinski, SK; Matthews, NS; Simon, BT	1
Azari, O; Ebrahimzadeh, F; Mashayekhi, H; Molaei, MM; Nahvi, A; Samimi, AS	1
Aghamiri, SM; Hajian, M; Oroumieh, A; Samimi, AM; Samimi, AS	1

Reviews

1 review(s) available for xylazine and detomidine

Article	Year
Alpha 2 adrenoceptor agonists in the horse--a review. The British veterinary journal, 1996, Volume: 152, Issue:6 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Medetomidine; Respiration; Xylazine	1996

Trials

22 trial(s) available for xylazine and detomidine

Article	Year
Comparison of detomidine, butorphanol, flunixin meglumine and xylazine in clinical cases of equine colic. Equine veterinary journal. Supplement, 1989, Issue:7 Topics: Adrenergic alpha-Agonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Butorphanol; Clonixin; Colic; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Injections, Intravenous; Respiration; Time Factors; Xylazine	1989
Reversal of sedative and clinicophysiological effects of epidural xylazine and detomidine with atipamezole and yohimbine in buffaloes (Bubalus bubalis). The Veterinary record, 1998, Nov-07, Volume: 143, Issue:19 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Buffaloes; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Epidural; Injections, Intravenous; Male; Respiration; Xylazine; Yohimbine	1998
Sedative and physiologic effects of orally administered alpha 2-adrenoceptor agonists and ketamine in cats. Journal of the American Veterinary Medical Association, 2000, Jun-15, Volume: 216, Issue:12 Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Body Temperature; Cats; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Ketamine; Male; Medetomidine; Oximetry; Oxygen; Prospective Studies; Respiration; Xylazine	2000
Comparison of four drug combinations for total intravenous anesthesia of horses undergoing surgical removal of an abdominal testis. Journal of the American Veterinary Medical Association, 2000, Sep-15, Volume: 217, Issue:6 Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Anti-Anxiety Agents; Blood Pressure; Cryptorchidism; Diazepam; Guaifenesin; Heart Rate; Horse Diseases; Horses; Imidazoles; Ketamine; Male; Thiopental; Tiletamine; Xylazine; Zolazepam	2000
The effects of xylazine, detomidine, acepromazine and butorphanol on equine solid phase gastric emptying rate. Equine veterinary journal, 2002, Volume: 34, Issue:5 Topics: Acepromazine; Adrenergic alpha-Agonists; Analgesics; Animals; Breath Tests; Butorphanol; Caprylates; Carbon Dioxide; Carbon Isotopes; Dose-Response Relationship, Drug; Gastric Emptying; Gastroparesis; Horses; Hypnotics and Sedatives; Imidazoles; Linear Models; Xylazine	2002
A comparison of the antinociceptive effects of xylazine, detomidine and romifidine on experimental pain in horses. Veterinary anaesthesia and analgesia, 2003, Volume: 30, Issue:3 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Cross-Over Studies; Female; Horses; Imidazoles; Male; Single-Blind Method; Xylazine	2003
Preliminary study of the effects of xylazine or detomidine with or without butorphanol for standing sedation in dairy cattle. Veterinary therapeutics : research in applied veterinary medicine, 2003,Fall, Volume: 4, Issue:3 Topics: Animals; Blood Pressure; Butorphanol; Cattle; Drug Combinations; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Infusions, Intravenous; Muscle Relaxation; Respiration; Xylazine	2003
The analgesic effects of intrathecal xylazine and detomidine in sheep and their antagonism with systemic atipamezole. Veterinary anaesthesia and analgesia, 2005, Volume: 32, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Animals, Laboratory; Cross-Over Studies; Female; Hemodynamics; Imidazoles; Prospective Studies; Sheep; Treatment Outcome; Xylazine	2005
Sedative effects of midazolam and xylazine with or without ketamine and detomidine alone following intranasal administration in Ring-necked Parakeets. Journal of the American Veterinary Medical Association, 2006, Feb-01, Volume: 228, Issue:3 Topics: Administration, Intranasal; Adrenergic alpha-Antagonists; Animals; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Midazolam; Parakeets; Prospective Studies; Respiration; Time Factors; Treatment Outcome; Xylazine; Yohimbine	2006
Clinical evaluation of intranasal benzodiazepines, alpha-agonists and their antagonists in canaries. Veterinary anaesthesia and analgesia, 2006, Volume: 33, Issue:3 Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Behavior, Animal; Benzodiazepines; Canaries; Diazepam; Drug Therapy, Combination; Female; Flumazenil; Hypnotics and Sedatives; Imidazoles; Male; Midazolam; Prospective Studies; Xylazine; Yohimbine	2006
Comparison of the effects of the alpha-2 agonists detomidine, romifidine and xylazine on nociceptive withdrawal reflex and temporal summation in horses. Veterinary anaesthesia and analgesia, 2009, Volume: 36, Issue:4 Topics: Animals; Cross-Over Studies; Female; Forelimb; Hindlimb; Horses; Imidazoles; Male; Pain; Reflex; Time Factors; Xylazine	2009
Influence of detomidine and xylazine on spleen dimensions and on splenic response to epinephrine infusion in healthy adult horses. Veterinary anaesthesia and analgesia, 2013, Volume: 40, Issue:4 Topics: Animals; Cross-Over Studies; Epinephrine; Female; Horses; Hypnotics and Sedatives; Imidazoles; Spleen; Xylazine	2013
Accelerometric comparison of the locomotor pattern of horses sedated with xylazine hydrochloride, detomidine hydrochloride, or romifidine hydrochloride. American journal of veterinary research, 2013, Volume: 74, Issue:6 Topics: Accelerometry; Anesthetics; Animals; Biomechanical Phenomena; Cross-Over Studies; Female; Gait; Horses; Hypnotics and Sedatives; Imidazoles; Male; Motor Activity; Xylazine	2013
Comparison of the mechanical hypoalgesic effects of five α2-adrenoceptor agonists in donkeys. The Veterinary record, 2013, Sep-28, Volume: 173, Issue:12 Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Anesthesia, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Equidae; Imidazoles; Medetomidine; Pain Threshold; Time Factors; Xylazine	2013
Effects of xylazine, romifidine, or detomidine on hematology, biochemistry, and splenic thickness in healthy horses. The Canadian veterinary journal = La revue veterinaire canadienne, 2014, Volume: 55, Issue:4 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Blood Urea Nitrogen; Erythrocyte Count; Female; Horses; Imidazoles; Osmolar Concentration; Osmotic Pressure; Sodium; Spleen; Xylazine	2014
Evaluation of the effects of commonly used α American journal of veterinary research, 2019, Volume: 80, Issue:9 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Butorphanol; Cross-Over Studies; Drug Therapy, Combination; Female; Forelimb; Gait; Horses; Imidazoles; Lameness, Animal; Male; Random Allocation; Xylazine	2019
Comparison of xylazine and detomidine in combination with midazolam/ketamine for field castration in Quarter Horses. Equine veterinary journal, 2020, Volume: 52, Issue:4 Topics: Animals; Horses; Imidazoles; Ketamine; Male; Midazolam; Orchiectomy; Xylazine	2020
Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation. Journal of veterinary internal medicine, 2020, Volume: 34, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Conscious Sedation; Cross-Over Studies; Female; Horses; Hypnotics and Sedatives; Imidazoles; Insulin; Male; Xylazine	2020
Xylazine or detomidine in dairy calves: a comparison of clinically relevant pharmacodynamic parameters under sedation. Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2021, Volume: 49, Issue:1 Topics: Administration, Intravenous; Animals; Biopsy, Needle; Bone Marrow; Cattle; Female; Hypnotics and Sedatives; Imidazoles; Male; Prospective Studies; Xylazine	2021
Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol, tiletamine-zolazepam-xylazine-butorphanol, and ketamine-detomidine-butorphanol in pigs. Journal of the American Veterinary Medical Association, 2021, Apr-15, Volume: 258, Issue:8 Topics: Anesthetics; Animals; Butorphanol; Cross-Over Studies; Drug Combinations; Heart Rate; Imidazoles; Ketamine; Male; Swine; Tiletamine; Xylazine; Zolazepam	2021
The effects of xylazine or detomidine when used as a pre-anesthetic sedative on recovery quality and duration in horses undergoing elective equine castration. The Canadian veterinary journal = La revue veterinaire canadienne, 2021, Volume: 62, Issue:9 Topics: Anesthetics; Animals; Horses; Hypnotics and Sedatives; Imidazoles; Male; Orchiectomy; Prospective Studies; Xylazine	2021
Effect of xylazine, detomidine, medetomidine and dexmedetomidine during laparoscopic SCNT embryo transfer on pregnancy rate and some physiological variables in goats. BMC veterinary research, 2022, Mar-15, Volume: 18, Issue:1 Topics: Animals; Dexmedetomidine; Embryo Transfer; Female; Goats; Imidazoles; Laparoscopy; Medetomidine; Pregnancy; Pregnancy Rate; Prospective Studies; Xylazine	2022

Other Studies

47 other study(ies) available for xylazine and detomidine

Article	Year
A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse. Journal of veterinary pharmacology and therapeutics, 1992, Volume: 15, Issue:2 Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Ataxia; Heart Rate; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Male; Penis; Photic Stimulation; Physical Stimulation; Sweating; Urination; Xylazine	1992
Ketamine, Telazol, xylazine and detomidine. A comparative anesthetic drug combinations study in ponies. Acta veterinaria Scandinavica, 1992, Volume: 33, Issue:2 Topics: Anesthetics; Animals; Drug Combinations; Horses; Imidazoles; Ketamine; Tiletamine; Xylazine; Zolazepam	1992
The effects of alpha 2 agonists and antagonists on hippocampal theta activity in the freely moving rat. Brain research bulletin, 1991, Volume: 26, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Atropine; Hippocampus; Imidazoles; Male; Motor Activity; Rats; Theta Rhythm; Tolazoline; Xylazine	1991
Stimulation of food intake in rats by the alpha 2-adrenoceptor agonists xylazine and detomidine. Pharmacological research, 1991, Volume: 23, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Eating; Imidazoles; Male; Rats; Xylazine; Yohimbine	1991
Use of scintigraphy for the determination of mucociliary clearance rates in normal, sedated, diseased and exercised horses. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1991, Volume: 55, Issue:4 Topics: Animals; Exercise Test; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Lung Diseases, Obstructive; Mucociliary Clearance; Physical Exertion; Radionuclide Imaging; Reproducibility of Results; Software; Trachea; Xylazine	1991
Cardiovascular effects of xylazine and detomidine in horses. American journal of veterinary research, 1991, Volume: 52, Issue:5 Topics: Analgesics; Animals; Electrocardiography; Female; Heart Block; Hematocrit; Hemodynamics; Horses; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Male; Myocardial Contraction; Oxygen; Respiration; Xylazine	1991
Haemodynamic changes during sedation in ponies. Veterinary research communications, 1990, Volume: 14, Issue:4 Topics: Animals; Atropine; Blood Gas Analysis; Blood Pressure; Cardiac Output; Female; Heart Rate; Hematocrit; Hemodynamics; Horses; Hypnotics and Sedatives; Imidazoles; Male; Promazine; Promethazine; Xylazine	1990
Cardiovascular effects of detomidine, a new alpha 2-adrenoceptor agonist, in the conscious pony. Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Blood Flow Velocity; Blood Pressure; Heart; Heart Rate; Horses; Imidazoles; Myocardium; Oxygen Consumption; Stroke Volume; Xylazine	1989
Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:1 Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, General; Animals; Barbiturates; Clonidine; Drug Synergism; Hypnotics and Sedatives; Imidazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Reflex; Xylazine	1985
Cardiovascular action of detomidine, a sedative and analgesic imidazole derivative with alpha-agonistic properties. European journal of pharmacology, 1985, Nov-26, Volume: 118, Issue:1-2 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Cats; Decerebrate State; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Imidazoles; Male; Rats; Rats, Inbred Strains; Xylazine	1985
Depression of reticulo-ruminal motor functions through the stimulation of alpha 2-adrenoceptors. Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Cattle; Clonidine; Female; Imidazoles; Muscle Contraction; Reticulum; Rumen; Sheep; Tolazoline; Xylazine; Yohimbine	1987
Influence of idazoxan on the respiratory blood gas changes induced by alpha 2-adrenoceptor agonist drugs in conscious sheep. The Veterinary record, 1987, Aug-01, Volume: 121, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Blood Gas Analysis; Carbon Dioxide; Dioxanes; Dioxins; Female; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Idazoxan; Imidazoles; Oxygen; Sheep; Thiazines; Xylazine	1987
Colonic alpha 2-adrenoceptor-mediated responses in the pony. Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:4 Topics: Adrenergic alpha-Agonists; Animals; Cecum; Colon; Dinoprost; Gastrointestinal Motility; Horses; Imidazoles; Prostaglandins F; Tolazoline; Xylazine	1987
Evaluation of the alpha 1- and alpha 2-adrenoceptor effects of detomidine, a novel veterinary sedative analgesic. European journal of pharmacology, 1985, Jan-22, Volume: 108, Issue:2 Topics: Analgesics; Animals; Clonidine; Electric Stimulation; Female; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Muscle Contraction; Muscle, Smooth; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Xylazine	1985
Comparison of the effects of detomidine and xylazine on some alpha 2-adrenoceptor-mediated responses in the central and peripheral nervous systems. European journal of pharmacology, 1985, Sep-24, Volume: 115, Issue:2-3 Topics: Animals; Blood Pressure; Body Temperature; Central Nervous System; Decerebrate State; Dose-Response Relationship, Drug; Female; Heart Rate; Imidazoles; Male; Mydriatics; Peripheral Nerves; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Thiazines; Xylazine	1985
Detomidine: a preliminary analysis of its duration of action in the horse by variable interval responding. Equine veterinary journal, 1988, Volume: 20, Issue:5 Topics: Animals; Behavior, Animal; Conditioning, Operant; Horses; Hypnotics and Sedatives; Imidazoles; Reinforcement Schedule; Xylazine	1988
The effect of sedatives on lung function in horses. Acta veterinaria Scandinavica. Supplementum, 1986, Volume: 82 Topics: Animals; Female; Hypnotics and Sedatives; Imidazoles; Lung; Male; Respiration; Thiazines; Xylazine	1986
Analgesic and sedative effects of detomidine compared to xylazine in a colic model using i.v. and i.m. routes of administration. Acta veterinaria Scandinavica. Supplementum, 1986, Volume: 82 Topics: Analgesics; Animals; Cecal Diseases; Colic; Female; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Male; Thiazines; Xylazine	1986
Effect of detomidine on the release and turnover of noradrenaline in rat brain. Acta pharmacologica et toxicologica, 1986, Volume: 58, Issue:5 Topics: alpha-Methyltyrosine; Analgesics; Animals; Brain; Dopamine; Imidazoles; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Xylazine; Yohimbine	1986
Antinociceptive activity and mechanism of action of detomidine. Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:3 Topics: Acetates; Acetic Acid; Analgesics; Animals; Female; Imidazoles; Mice; Mice, Inbred Strains; Morphine; Pain; Rats; Xylazine	1986
Effects of diazepam, acepromazine, detomidine, and xylazine on thiamylal anesthesia in horses. Journal of the American Veterinary Medical Association, 1993, Oct-01, Volume: 203, Issue:7 Topics: Acepromazine; Anesthesia; Animals; Diazepam; Female; Hemodynamics; Horses; Hypnotics and Sedatives; Imidazoles; Male; Preanesthetic Medication; Respiration; Thiamylal; Xylazine	1993
Immobilization and anesthesia of two hand-reared zebras. Journal of the American Veterinary Medical Association, 1993, Mar-15, Volume: 202, Issue:6 Topics: Anesthesia; Animals; Ataxia; Guaifenesin; Halothane; Hoof and Claw; Hypnotics and Sedatives; Imidazoles; Immobilization; Male; Perissodactyla; Radiography; Thiamylal; Tiletamine; Xylazine; Zolazepam	1993
Evaluation of propofol for general anesthesia in premedicated horses. American journal of veterinary research, 1996, Volume: 57, Issue:4 Topics: Anesthesia, General; Anesthetics; Anesthetics, Intravenous; Animals; Behavior, Animal; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Horses; Hypnotics and Sedatives; Imidazoles; Male; Orchiectomy; Oxygen; Partial Pressure; Premedication; Propofol; Respiration; Time Factors; Xylazine	1996
Cardiopulmonary and analgesic effects of xylazine, detomidine, medetomidine, and the antagonist atipamezole in isoflurane-anesthetized swine. Laboratory animal science, 1996, Volume: 46, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics; Anesthesia; Animals; Blood Pressure; Heart; Heart Rate; Imidazoles; Isoflurane; Lung; Medetomidine; Swine; Vascular Resistance; Xylazine	1996
Effects of alpha 2-agonists on intrauterine pressure and sedation in horses: comparison between detomidine, romifidine and xylazine. Zentralblatt fur Veterinarmedizin. Reihe A, 1994, Volume: 41, Issue:7 Topics: Adrenergic alpha-Agonists; Anesthetics; Animals; Female; Horses; Hypnotics and Sedatives; Imidazoles; Pressure; Uterus; Xylazine	1994
Comparison of antinociceptive, cardiovascular, and respiratory effects, head ptosis, and position of pelvic limbs in mares after caudal epidural administration of xylazine and detomidine hydrochloride solution. American journal of veterinary research, 1996, Volume: 57, Issue:9 Topics: Adrenergic alpha-Agonists; Analgesia, Epidural; Animals; Blood Pressure; Cardiac Output; Female; Head; Heart Rate; Hemodynamics; Horses; Imidazoles; Pain; Posture; Pulmonary Circulation; Respiration; Stroke Volume; Vascular Resistance; Xylazine	1996
Extralabel use of tranquilizers and general anesthetics. Journal of the American Veterinary Medical Association, 1997, Aug-01, Volume: 211, Issue:3 Topics: Acepromazine; Anesthetics, General; Animals; Atropine; Barbiturates; Cattle; Consumer Product Safety; Databases, Factual; Drug Approval; Drug Labeling; Drug Residues; Female; Fishes; Goats; Guaifenesin; Imidazoles; Ketamine; Lidocaine; Swine; Tiletamine; Time Factors; Tranquilizing Agents; United States; Xylazine; Yohimbine; Zolazepam	1997
Development and characterization of an equine behaviour chamber and the effects of amitraz and detomidine on spontaneous locomotor activity. Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:5 Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Fentanyl; Horses; Hypnotics and Sedatives; Imidazoles; Injections, Intravenous; Insect Repellents; Locomotion; Male; Motor Activity; Narcotics; Toluidines; Xylazine	1997
The comparative hypoxaemic effect of four alpha 2 adrenoceptor agonists (xylazine, romifidine, detomidine and medetomidine) in sheep. Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:6 Topics: Adrenergic alpha-Agonists; Analgesics; Anesthetics; Animals; Female; Hemodynamics; Hypoxia; Imidazoles; Injections, Intravenous; Medetomidine; Sheep; Xylazine	1997
Effect of xylazine, detomidine, and a combination of xylazine and butorphanol on equine duodenal motility. American journal of veterinary research, 1998, Volume: 59, Issue:5 Topics: Analgesics, Opioid; Animals; Butorphanol; Drug Combinations; Duodenum; Female; Gastrointestinal Motility; Horses; Imidazoles; Male; Pressure; Xylazine	1998
Affinity of detomidine, medetomidine and xylazine for alpha-2 adrenergic receptor subtypes. Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Line; HT29 Cells; Humans; Hypnotics and Sedatives; Imidazoles; Medetomidine; PC12 Cells; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Xylazine	1998
Alpha-2 agonist dissociative anesthetic combinations in fallow deer (Cervus dama). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1999, Volume: 30, Issue:3 Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Body Temperature; Deer; Female; Heart Rate; Imidazoles; Ketamine; Male; Muscle Relaxation; Respiration; Tiletamine; Time Factors; Xylazine; Zolazepam	1999
Cardiorespiratory and metabolic effects of xylazine, detomidine, and a combination of xylazine and acepromazine administered after exercise in horses. American journal of veterinary research, 1999, Volume: 60, Issue:10 Topics: Acepromazine; Analgesics; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Drug Interactions; Female; Heart Rate; Hemodynamics; Horses; Hypnotics and Sedatives; Imidazoles; Male; Oxygen; Oxygen Consumption; Physical Conditioning, Animal; Physical Exertion; Pulmonary Artery; Vascular Resistance; Xylazine	1999
Cardiovascular effects of medetomidine, detomidine and xylazine in horses. The Journal of veterinary medical science, 2000, Volume: 62, Issue:10 Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Blood Gas Analysis; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate; Horses; Imidazoles; Injections, Intravenous; Medetomidine; Receptors, Adrenergic, alpha; Respiration; Xylazine	2000
In vitro effects of oxytocin, acepromazine, detomidine, xylazine, butorphanol, terbutaline, isoproterenol, and dantrolene on smooth and skeletal muscles of the equine esophagus. American journal of veterinary research, 2002, Volume: 63, Issue:12 Topics: Acepromazine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Butorphanol; Dantrolene; Dopamine Antagonists; Electric Stimulation; Esophagus; Horses; Imidazoles; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Relaxants, Central; Muscle, Skeletal; Muscle, Smooth; Oxytocin; Terbutaline; Xylazine	2002
Effects of treatment with oxytocin, xylazine butorphanol, guaifenesin, acepromazine, and detomidine on esophageal manometric pressure in conscious horses. American journal of veterinary research, 2002, Volume: 63, Issue:12 Topics: Acepromazine; Adrenergic alpha-Agonists; Animals; Butorphanol; Deglutition; Dopamine Antagonists; Esophagus; Female; Guaifenesin; Horses; Imidazoles; Male; Manometry; Muscle Relaxants, Central; Oxytocin; Xylazine	2002
Effects of alpha-2 adrenoceptor agonists during recovery from isoflurane anaesthesia in horses. Equine veterinary journal, 2003, Volume: 35, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Animals; Blood Pressure; Female; Heart Rate; Horses; Imidazoles; Isoflurane; Male; Receptors, Adrenergic, alpha-2; Sodium Chloride; Xylazine	2003
Interactions of xylazine and detomidine with alpha2-adrenoceptors in brain tissue from cattle, swine and rats. Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Brain; Brain Stem; Cattle; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Species Specificity; Swine; Xylazine	2003
Effects of alpha2-adrenergic receptor agonists on urine production in horses deprived of food and water. American journal of veterinary research, 2004, Volume: 65, Issue:10 Topics: Adrenergic Agonists; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Food Deprivation; Glycosuria; Horses; Imidazoles; Potassium; Receptors, Adrenergic, alpha-2; Sodium; Urination; Water Deprivation; Xylazine	2004
Effects of xylazine, medetomidine, detomidine, and diazepam on sedation, heart and respiratory rates, and cloacal temperature in rock partridges (Alectoris graeca). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2006, Volume: 37, Issue:2 Topics: Animals; Cloaca; Diazepam; Female; Galliformes; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Random Allocation; Respiration; Time Factors; Xylazine	2006
The use of alpha-2 agonists in the equine practice: comparison between three molecules. Veterinary research communications, 2007, Volume: 31 Suppl 1 Topics: Adrenergic alpha-Agonists; Animals; Ataxia; Female; Horses; Hypnotics and Sedatives; Imidazoles; Male; Xylazine	2007
Vascular perfusion of reproductive organs in pony mares and heifers during sedation with detomidine or xylazine. American journal of veterinary research, 2009, Volume: 70, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Blood Flow Velocity; Blood Pressure; Cattle; Corpus Luteum; Endometrium; Female; Heart Rate; Horses; Iliac Artery; Imidazoles; Random Allocation; Ultrasonography, Doppler, Color; Xylazine	2009
Total intravenous anesthesia with midazolam, ketamine, and xylazine or detomidine following induction with tiletamine, zolazepam, and xylazine in red deer (Cervus elaphus hippelaphus) undergoing surgery. Journal of wildlife diseases, 2010, Volume: 46, Issue:4 Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Deer; Female; Heart Rate; Imidazoles; Ketamine; Midazolam; Tiletamine; Xylazine; Zolazepam	2010
Pulmonary gas exchange and acid-base status during immobilisation of black rhinoceroses ( Journal of the South African Veterinary Association, 2016, Dec-02, Volume: 87, Issue:1 Topics: Acid-Base Equilibrium; Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Animals, Wild; Azaperone; Dopamine Antagonists; Etorphine; Female; Fentanyl; Imidazoles; Immobilization; Male; Perissodactyla; Pulmonary Gas Exchange; Xylazine; Zimbabwe	2016
Effects of selective α Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:2 Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Bronchi; Carbachol; Electric Stimulation; Horses; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Xylazine	2018
Protocols using detomidine and oxytocin induce ex copula ejaculation in stallions. Theriogenology, 2019, Volume: 140 Topics: Animals; Ejaculation; Horses; Imidazoles; Imipramine; Male; Oxytocin; Semen Analysis; Sperm Count; Sperm Retrieval; Xylazine	2019
Evaluation of the sedative and physiological effects of xylazine, detomidine, medetomidine and dexmedetomidine in goats. Veterinary medicine and science, 2022, Volume: 8, Issue:3 Topics: Adrenergic Agonists; Animals; Dexmedetomidine; Goats; Hypnotics and Sedatives; Imidazoles; Medetomidine; Xylazine	2022