xylazine has been researched along with clonidine in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (54.29) | 18.7374 |
| 1990's | 22 (31.43) | 18.2507 |
| 2000's | 8 (11.43) | 29.6817 |
| 2010's | 1 (1.43) | 24.3611 |
| 2020's | 1 (1.43) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| de Jonge, A; Lam, E; Slothorst-Grisdijk, FP; Timmermans, PB; van Meel, JC; van Zwieten, PA | 1 |
| Bonhaus, DW; Chang, LK; Chang, TK; Daunt, DA; Eglen, RM; Hsu, SA; Jasper, JR; Lesnick, JD; Yamanishi, SS | 1 |
| Kobinger, W; Pichler, L | 1 |
| Bentley, GA; Nolan, PL | 1 |
| Finch, L | 2 |
| Sperlágh, B; Vizi, ES | 1 |
| Akiba, T; Hikasa, Y; Iino, Y; Matsukura, M; Ogasawara, S; Takase, K | 1 |
| van Duin, CT; van Miert, AS | 1 |
| Devi, K; Hrishikeshavan, HJ; Munonyedi, US; Shanbhogue, RS | 1 |
| Dóda, M; Vizi, ES | 1 |
| Harsing, LG; Kapocsi, J; Vizi, ES | 1 |
| Hattori, N; Imura, H; Ishikawa, Y; Kato, Y; Koshiyama, H; Murakami, Y; Shimatsu, A | 1 |
| McGrath, JC | 2 |
| Nyman, L; Ruskoaho, H; Virtanen, R | 1 |
| Colpaert, FC; Janssen, PA | 1 |
| Livingston, A; Nolan, A; Waterman, A | 2 |
| Bernardini, C; Del Tacca, M; Martinotti, E; Soldani, G | 1 |
| Allal, C; Ruckebusch, Y | 1 |
| Bouchenafa, O; Livingston, A; Waterman, A | 1 |
| Allen, JM; McCarron, JG; McHale, NG; Thornbury, KD | 1 |
| Doak, N; Fleming, WW; Leedham, JA; Taylor, DA | 1 |
| Nyman, L; Virtanen, R | 1 |
| Kobinger, W | 1 |
| Burke, JA; Potter, DE | 1 |
| Docherty, JR; Hyland, L | 1 |
| Corrigan, SA; Pfaff, DW; Zemlan, FP | 1 |
| Gallanosa, AG; Morris, DL; Shipe, JR; Spyker, DA | 1 |
| Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG | 1 |
| Cavero, I; Doxey, JC; Roach, AG; Strachan, DA | 1 |
| Henderson, JK; Hynes, MD | 1 |
| Lues, I; Schümann, HJ | 1 |
| Glusa, E; Markwardt, F | 1 |
| Atlas, D; Hynes, MD; Ruffolo, RR | 1 |
| Hsu, WH; Kakuk, TJ | 1 |
| Colpaert, FC | 1 |
| Livingston, A; Low, J; Morris, B | 1 |
| Leander, JD; McCleary, PE | 1 |
| Altszuler, N; Hampshire, J | 1 |
| Paul, D; Tran, JG | 1 |
| Chambers, JP; Livingston, A; Muge, DK | 1 |
| Cosentino, M; De Ponti, F; Frigo, GM; Lecchini, S; Marcoli, M; Marino, F | 1 |
| Corcoran, ME; Pelletier, MR | 1 |
| Butelman, ER; Woods, JH | 1 |
| Chiba, S; Skrbic, R | 1 |
| Docherty, JR; Kearns, S; O'Rourke, M | 1 |
| Campion, DP; Leek, BF | 1 |
| Docherty, JR | 1 |
| Cao, W; Cheng, T; Li, Y; Steinberg, RH; Wen, R | 1 |
| Badia, A; Giraldo, J; Sallés, J; Vila, E | 1 |
| Clarke, KW; England, GC | 1 |
| De Kock, M; Meert, TF | 1 |
| Laties, AM; Li, Y; Liu, C; Luo, Z; Peng, M; Wen, R | 1 |
| Fukui, H; Hikasa, Y; Matsuda, H; Ogasawara, S; Sato, Y | 1 |
| Akamatsu, H; Maekawa, N; Mikawa, K; Nishina, K; Niwa, Y; Obara, H; Shiga, M | 1 |
| Atwal, OS; Black, WD; Celly, CS; McDonell, WN | 1 |
| Bischoff, FP; Braeken, M; Kennis, LE; Leysen, JE; Love, CJ; Megens, AA; Mertens, CJ; Pieters, S; Van den Keybus, FA | 1 |
| Atalik, KE; Doğan, N; Sahin, AS | 1 |
| Altobelli, D; Martire, M; Maurizi, S; Preziosi, P | 1 |
| Chiba, S; Taguchi, Y; Yang, XP | 1 |
| Ren, LM; Zhao, D | 1 |
| Kardan, A; Mehr, SE; Samini, M | 1 |
| Gyires, K; Kató, E; Lipták, L; Mátyus, P; Rónai, AZ; Shujaa, N | 1 |
| Almeida, RM; Dória, RG; Duque, JC; Farias, A; Netto, AC; Valadão, CA | 1 |
| Hainz, N; Kovačević, B; Meier, C; Rzagalinski, I; Tschernig, T; Volmer, DA | 1 |
| Dong, Z; Dou, C; Miller, DL; Raghavendran, K | 1 |
3 review(s) available for xylazine and clonidine
| Article | Year |
|---|---|
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors.
Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine | 1986 |
Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants.
Topics: Adult; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clonidine; Female; Gas Chromatography-Mass Spectrometry; Humans; Phenothiazines; Thiazines; Veterinary Medicine; Xylazine | 1981 |
Alpha 2 adrenoceptor agonists in the horse--a review.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Horses; Hypnotics and Sedatives; Imidazoles; Medetomidine; Respiration; Xylazine | 1996 |
1 trial(s) available for xylazine and clonidine
| Article | Year |
|---|---|
Comparative study of epidural xylazine or clonidine in horses.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Animals; Behavior, Animal; Clonidine; Double-Blind Method; Female; Heart Rate; Horses; Injections, Epidural; Male; Pain Measurement; Pain, Postoperative; Respiration; Treatment Outcome; Xylazine | 2008 |
66 other study(ies) available for xylazine and clonidine
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction | 1984 |
Characterization of alpha-adrenoceptor populations. Quantitative relationships between cardiovascular effects initiated at central and peripheral alpha-adrenoceptors.
Topics: Animals; Blood Pressure; Blood Vessels; Brain; Hemodynamics; Male; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Cyclic AMP; Genetic Vectors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Protein Binding; Quinolizines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Proteins | 1998 |
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine | 1975 |
Studies on orthostatic cardiovascular responses in anaesthetized cats.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Bretylium Compounds; Cats; Clonidine; Guanethidine; Hemodynamics; Hypotension, Orthostatic; Norepinephrine; Oxymetazoline; Time Factors; Xylazine | 1975 |
The central hypotensive action of clonidine and BAY 1470 in cats and rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Clonidine; Heart Rate; Hypertension; Injections, Intraventricular; Rats; Species Specificity; Thiazines; Xylazine | 1975 |
Is the neuronal ATP release from guinea-pig vas deferens subject to alpha 2-adrenoceptor-mediated modulation?
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Electric Stimulation; Guinea Pigs; Imidazoles; Male; Medetomidine; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine; Yohimbine | 1992 |
Central alpha-adrenoceptor subtypes involved in the emetic pathway in cats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Male; Methoxamine; Oxidopamine; Receptors, Adrenergic, alpha; Reserpine; Vomiting; Xylazine | 1992 |
Feed intake and rumen motility in dwarf goats. Effects of some alpha 2-adrenergic agonists, prostaglandins and posterior pituitary hormones.
Topics: Adrenergic alpha-Agonists; Alprostadil; Animals; Body Temperature; Clonidine; Dinoprost; Eating; Felypressin; Female; Gastrointestinal Motility; Goats; Heart Rate; Male; Oxytocin; Pituitary Hormones, Posterior; Prostaglandins; Prostaglandins F, Synthetic; Rumen; Vasopressins; Xylazine | 1991 |
Potentiation of poststartle activity by conditioned fear: effects of anxiolytic and anxiogenic drugs.
Topics: Animals; Anti-Anxiety Agents; Arousal; Buspirone; Clonidine; Conditioning, Classical; Diazepam; Dose-Response Relationship, Drug; Fear; Male; Rats; Rats, Inbred Strains; Reflex, Startle; Xylazine; Yohimbine | 1991 |
Effect of CH-38083, a selective antagonist of alpha 2-adrenoceptors, on renal sympathetic function.
Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Berberine Alkaloids; Blood Pressure; Cats; Clonidine; Dimethylphenylpiperazinium Iodide; Dioxanes; Female; Idazoxan; Kidney; Male; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Xylazine | 1989 |
Possible role of alpha-2 and alpha-1 adrenoceptors in the experimentally-induced depression of the central nervous system.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Chickens; Clonidine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Hydroxydopamines; Male; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Reflex; Thiazines; Xylazine | 1989 |
Possible involvement of endogenous opioid peptides in prolactin secretion induced by alpha 2-adrenergic stimulation in rats.
Topics: Animals; Cerebral Ventricles; Clonidine; Endorphins; Epinephrine; Injections, Intraventricular; Male; Naloxone; Norepinephrine; Phentolamine; Prolactin; Rats; Rats, Inbred Strains; Reference Values; Thiazines; Xylazine | 1989 |
alpha-Adrenoceptor agonists and the Ca2+-dependence of smooth muscle contraction: evidence for subtypes of receptors or for agonist-dependent differences in the agonist-receptor interaction?
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Ethanolamines; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine | 1985 |
Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic.
Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, General; Animals; Barbiturates; Clonidine; Drug Synergism; Hypnotics and Sedatives; Imidazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Reflex; Xylazine | 1985 |
Discriminative stimulus properties of xylazine in rat: discriminability and effects of putative alpha-2 adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Discrimination Learning; Idazoxan; Lisuride; Lysergic Acid Diethylamide; Male; Piperoxan; Rats; Rats, Inbred Strains; Thiazines; Xylazine; Yohimbine | 1985 |
The effects of alpha 2 adrenoceptor agonists on airway pressure in anaesthetized sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Airway Resistance; Animals; Clonidine; Dioxanes; Female; Histamine; Idazoxan; Injections, Intravenous; Injections, Intraventricular; Methoxamine; Prazosin; Pyrilamine; Sheep; Tripelennamine; Xylazine | 1986 |
The effects of alpha-2 agonists and antagonists on gastric acid secretion.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Gastric Juice; Guanabenz; Guinea Pigs; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Tolazoline; Xylazine; Yohimbine | 1986 |
Depression of reticulo-ruminal motor functions through the stimulation of alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Cattle; Clonidine; Female; Imidazoles; Muscle Contraction; Reticulum; Rumen; Sheep; Tolazoline; Xylazine; Yohimbine | 1987 |
Antinociceptive actions of intravenous alpha 2-adrenoceptor agonists in sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Hot Temperature; Idazoxan; Injections, Intravenous; Nociceptors; Pressure; Sheep; Thiazines; Xylazine | 1987 |
Analgesic effects of intrathecally-applied alpha 2-adrenoceptor agonists in conscious, unrestrained sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Injections, Spinal; Sheep; Time Factors; Xylazine | 1988 |
Release of [3H]-noradrenaline from the sympathetic nerves to bovine mesenteric lymphatic vessels and its modification by alpha-agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cattle; Clonidine; Cocaine; Electric Stimulation; Feedback; Lymphatic System; Mesentery; Norepinephrine; Phentolamine; Phenylephrine; Prazosin; Sympathetic Nervous System; Tetrodotoxin; Xylazine; Yohimbine | 1988 |
Morphine tolerance and nonspecific subsensitivity of the longitudinal muscle myenteric plexus preparation of the guinea-pig to inhibitory agonists.
Topics: 2-Chloroadenosine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Guinea Pigs; Ileum; Male; Morphine; Muscle, Smooth; Myenteric Plexus; Xylazine | 1988 |
Evaluation of the alpha 1- and alpha 2-adrenoceptor effects of detomidine, a novel veterinary sedative analgesic.
Topics: Analgesics; Animals; Clonidine; Electric Stimulation; Female; Hypnotics and Sedatives; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Mice; Muscle Contraction; Muscle, Smooth; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Xylazine | 1985 |
The ocular effects of xylazine in rabbits, cats, and monkeys.
Topics: Animals; Cats; Cebus; Clonidine; Female; Intraocular Pressure; Male; Nictitating Membrane; Pupil; Rabbits; Sympathetic Nervous System; Thiazines; Timolol; Xylazine | 1986 |
Further examination of the effects of ageing on the adrenoceptor responsiveness of the rat vas deferens.
Topics: Aging; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Vas Deferens; Xylazine | 1985 |
The cardiovascular effects of intraventricular clonidine and Bay 1470 in conscious hypertensive cats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dioxanes; Dopamine Antagonists; Haloperidol; Heart Rate; Hemodynamics; Hypertension, Renal; Phentolamine; Piperidines; Thiazines; Time Factors; Xylazine | 1974 |
Noradrenergic and serotonergic mediation of spinal analgesia mechanisms.
Topics: Analgesics; Animals; Clonidine; Cordotomy; Female; Hypnotics and Sedatives; Neural Inhibition; Neurotransmitter Agents; Norepinephrine; Quipazine; Rats; Reaction Time; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Spinal Cord; Sympathomimetics; Time Factors; Xylazine | 1980 |
Pharmacological evidence favoring a similarity between alpha adrenoceptors mediating sleep in chicks and cardiac presynaptic alpha-2 receptors in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chickens; Clonidine; Guanfacine; Guanidines; Heart; Heart Rate; Male; Methoxamine; Nordefrin; Oxymetazoline; Phentolamine; Phenylacetates; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Neurotransmitter; Sleep; Xylazine; Yohimbine | 1982 |
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Brimonidine Tartrate; Chickens; Clonidine; Guanabenz; Guanfacine; Guanidines; Imidazoles; Phenylacetates; Quinoxalines; Receptors, Adrenergic, alpha; Sleep; Thiophenes; Time Factors; Xylazine | 1983 |
Modification of alpha-adrenoceptor agonist antinociceptive activity by nisoxetine: a selective inhibitor of noradrenergic uptake.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Mice; Norepinephrine; Propylamines; Xylazine | 1984 |
Alpha-adrenoceptor antagonism by apoyohimbine and some observations on the pharmacology of alpha-adrenoceptors in the rat anococcygeus and vas deferens.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Electric Stimulation; Ethanolamines; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Vas Deferens; Xylazine; Yohimbine | 1984 |
Effect of removing the endothelial cells on the reactivity of rat aortic segments to different alpha-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Azepines; Clonidine; Endothelium; Imidazoles; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Xylazine; Yohimbine | 1984 |
Influence of clonidine-like hypotensive drugs on adrenergic platelet reactions.
Topics: Antihypertensive Agents; Blood Platelets; Clonidine; Epinephrine; Guanabenz; Guanfacine; Guanidines; Humans; In Vitro Techniques; Phenylacetates; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Xylazine | 1981 |
Antinociceptive activity of N-(4-hydroxyphenacetyl)-4-aminoclonidine, a novel analog of clonidine: role of opioid receptors and alpha-adrenoceptors.
Topics: Analgesics; Animals; Aorta, Thoracic; Benzeneacetamides; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Kinetics; Male; Mice; Morphine; Naloxone; Receptors, Adrenergic, alpha; Receptors, Opioid; Xylazine; Yohimbine | 1983 |
Effect of amitraz and chlordimeform on heart rate and pupil diameter in rats: mediated by alpha 2-adrenoreceptors.
Topics: alpha-Methyltyrosine; Amidines; Animals; Chlorphenamidine; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Insecticides; Male; Methyltyrosines; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine; Toluidines; Xylazine | 1984 |
Cross generalization with LSD and yohimbine in the rat.
Topics: Animals; Clonidine; Discrimination, Psychological; Generalization, Response; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Xylazine; Yohimbine | 1984 |
Effects of clonidine and xylazine on body temperature in the rat.
Topics: Animals; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Rats; Rats, Inbred Strains; Temperature; Thiazines; Time Factors; Xylazine; Yohimbine | 1984 |
Clonidine analgesia and suppression of operant responding: dissociation of mechanism.
Topics: Analgesics; Animals; Clonidine; Conditioning, Operant; Drug Interactions; Fluoxetine; Male; Norepinephrine; Phenoxybenzamine; Rats; Xylazine; Yohimbine | 1981 |
Clonidine or xylazine as provocative tests for growth hormone secretion in the dog.
Topics: Animals; Blood Glucose; Clonidine; Dogs; Dose-Response Relationship, Drug; Growth Hormone; Phentolamine; Thiazines; Xylazine | 1981 |
Differential cross-tolerance between analgesia produced by alpha 2-adrenoceptor agonists and receptor subtype selective opioid treatments.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Analgesics; Animals; Binding Sites; Clonidine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Xylazine | 1995 |
Radioreceptor assay for determination of xylazine and medetomidine in sheep plasma.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Catecholamines; Cerebral Cortex; Clonidine; Female; Imidazoles; Isotope Labeling; Male; Medetomidine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Reference Standards; Sheep; Spectrophotometry, Ultraviolet; Tritium; Xylazine | 1995 |
Effect of desipramine-induced blockade of neuronal uptake mechanisms on adrenoceptor-mediated responses in the guinea-pig colon.
Topics: Acetylcholine; Adrenergic Agonists; Animals; Clonidine; Colon; Desipramine; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth; Neurons; Norepinephrine; Peristalsis; Phenylephrine; Receptors, Adrenergic; Xylazine | 1994 |
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Benzazepines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Functional Laterality; Idazoxan; Infusions, Parenteral; Kindling, Neurologic; Male; Rats; Receptors, Adrenergic, alpha-2; Seizures; Xylazine; Yohimbine | 1993 |
Effects of clonidine, dexmedetomidine and xylazine on thermal antinociception in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Azocines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Rate; Hot Temperature; Idazoxan; Imidazoles; Macaca mulatta; Male; Medetomidine; Muscle Relaxation; Pain Threshold; Respiration; Xylazine | 1993 |
Dominant antagonistic action of alpha 2-adrenoceptor agonists on alpha 1-agonist-induced vasoconstriction.
Topics: Animals; Clonidine; Dogs; Female; Macaca; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha; Serotonin; Species Specificity; Vasoconstriction; Xylazine | 1993 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
The effects of intracoeliac injections of alpha-adrenergic agonists and veratridine on reticuloruminal motility and the evocation of rumination in sheep.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Gastrointestinal Motility; Imidazoles; Injections, Intra-Arterial; Medetomidine; Phenylephrine; Rumen; Sheep; Veratridine; Xylazine | 1995 |
Effects of aging on prejunctional control of neurotransmission in the rat.
Topics: Adrenergic Fibers; Aging; Animals; Catecholamines; Clonidine; Male; Neurotransmitter Agents; Presynaptic Terminals; Rats; Vas Deferens; Xylazine | 1996 |
Alpha 2-adrenergic agonists induce basic fibroblast growth factor expression in photoreceptors in vivo and ameliorate light damage.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Fibroblast Growth Factor 2; Gene Expression Regulation; Injections; Light; Male; Neuroprotective Agents; Photoreceptor Cells; Rats; Rats, Sprague-Dawley; Retina; RNA, Messenger; Tissue Distribution; Xylazine | 1996 |
Modelling the changes induced by chronic desipramine treatment on the factors governing the agonism at prejunctional alpha 2-adrenoceptors.
Topics: Adrenergic Uptake Inhibitors; Animals; Clonidine; Desipramine; Dose-Response Relationship, Drug; Logistic Models; Male; Models, Biological; Muscle, Smooth; Quinolines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Xylazine | 1996 |
Alpha 2-adrenoceptor agonists and stress-induced analgesia in rats: influence of stressors and methods of analysis.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesia; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Clonidine; Dose-Response Relationship, Drug; Handling, Psychological; Housing, Animal; Imidazoles; Immobilization; Male; Medetomidine; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Stress, Psychological; Xylazine | 1997 |
Alpha2-adrenergic agonists selectively activate extracellular signal-regulated kinases in Müller cells in vivo.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Clonidine; Immunoblotting; Immunoenzyme Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuroglia; Phosphorylation; Rats; Rats, Sprague-Dawley; Retina; Signal Transduction; Xylazine | 1998 |
Platelet and brain alpha 2-adrenoceptors and cardiovascular sensitivity to agonists in dogs suffering from endotoxic shock.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Platelets; Brain; Catecholamines; Cerebral Cortex; Clonidine; Dogs; Endotoxins; Female; Male; Medulla Oblongata; Receptors, Adrenergic, alpha-2; Shock, Septic; Xylazine; Yohimbine | 1998 |
The effects of clonidine and dexmedetomidine on human neutrophil functions.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Calcium; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Clonidine; Free Radical Scavengers; Humans; Imidazoles; Infections; Medetomidine; Neutrophil Activation; Neutrophils; Phagocytosis; Reactive Oxygen Species; Superoxides; Xylazine | 1999 |
Histopathologic alterations induced in the lungs of sheep by use of alpha2-adrenergic receptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Female; Hypnotics and Sedatives; Lung; Lung Diseases; Macrophages; Microscopy, Electron; Sheep; Sheep Diseases; Xylazine | 1999 |
New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; CHO Cells; Clonidine; Cricetinae; Humans; Male; Prazosin; Pyridines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-2; Xylazine; Yohimbine | 2000 |
Interactions between phenylephrine, clonidine and xylazine in rat and rabbit aortas.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Phenylephrine; Rabbits; Rats; Vasodilation; Xylazine | 2000 |
Interaction of formamidine pesticides with the presynaptic alpha(2)-adrenoceptor regulating.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Chlorphenamidine; Clonidine; Dose-Response Relationship, Drug; Female; Hypothalamus; Imidazoles; Indoles; Insecticides; Isoindoles; Norepinephrine; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Synaptosomes; Toluidines; Tritium; Xylazine; Yohimbine | 2001 |
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alveolar Process; Animals; Arteries; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mandible; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction; Xylazine; Yohimbine | 2001 |
Electrophysiological responses to imidazoline/alpha2-receptor agonists in rabbit sinoatrial node pacemaker cells.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Agonists; Agmatine; Animals; Antihypertensive Agents; Aorta, Thoracic; Clonidine; Imidazoles; Male; Rabbits; Sinoatrial Node; Vasoconstriction; Xylazine | 2003 |
Alpha-2 agonists decrease expression of morphine-induced conditioned place preference.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Clonidine; Conditioning, Operant; Male; Mice; Morphine; Receptors, Adrenergic, alpha-2; Reward; Xylazine; Yohimbine | 2008 |
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Terbutaline; Vas Deferens; Vasodilation; Xylazine; Yohimbine | 2008 |
Toward Higher Sensitivity in Quantitative MALDI Imaging Mass Spectrometry of CNS Drugs Using a Nonpolar Matrix.
Topics: Animals; Brain Chemistry; Calibration; Central Nervous System Agents; Clonidine; Clozapine; Hydrophobic and Hydrophilic Interactions; Imipramine; Ketamine; Limit of Detection; Mice, Inbred C57BL; Nitriles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xylazine | 2018 |
The Influence of Xylazine and Clonidine on Lung Ultrasound-Induced Pulmonary Capillary Hemorrhage in Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Capillaries; Clonidine; Hemorrhage; Hypertension; Lung; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ultrasonic Waves; Ultrasonography; Xylazine | 2021 |