xct790 and vanillin

xct790 has been researched along with vanillin* in 1 studies

Other Studies

1 other study(ies) available for xct790 and vanillin

Article	Year
Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha. Journal of medicinal chemistry, 2004, Nov-04, Volume: 47, Issue:23 The estrogen-related receptor alpha (ERRalpha) is an orphan receptor belonging to the nuclear receptor superfamily. The physiological role of ERRalpha has yet to be established primarily because of lack of a natural ligand. Herein, we describe the discovery of the first potent and selective inverse agonist of ERRalpha. Through in vitro and in vivo studies, these ligands will elucidate the endocrine signaling pathways mediated by ERRalpha including association with human disease states. Topics: Acrylamides; Animals; Benzaldehydes; Cells, Cultured; Combinatorial Chemistry Techniques; ERRalpha Estrogen-Related Receptor; Nitriles; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Signal Transduction; Stereoisomerism; Structure-Activity Relationship; Thiadiazoles; Thiazoles	2004

Article

Year

Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha.

Journal of medicinal chemistry, 2004, Nov-04, Volume: 47, Issue:23

The estrogen-related receptor alpha (ERRalpha) is an orphan receptor belonging to the nuclear receptor superfamily. The physiological role of ERRalpha has yet to be established primarily because of lack of a natural ligand. Herein, we describe the discovery of the first potent and selective inverse agonist of ERRalpha. Through in vitro and in vivo studies, these ligands will elucidate the endocrine signaling pathways mediated by ERRalpha including association with human disease states.

Topics: Acrylamides; Animals; Benzaldehydes; Cells, Cultured; Combinatorial Chemistry Techniques; ERRalpha Estrogen-Related Receptor; Nitriles; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; Signal Transduction; Stereoisomerism; Structure-Activity Relationship; Thiadiazoles; Thiazoles

2004