xanthosine 5'-triphosphate has been researched along with xanthine in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (24.59) | 18.7374 |
| 1990's | 15 (24.59) | 18.2507 |
| 2000's | 15 (24.59) | 29.6817 |
| 2010's | 14 (22.95) | 24.3611 |
| 2020's | 2 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Heyde, E; Morrison, JF; Nagabhushanam, A; Vonarx, M | 1 |
| Maskos, K | 1 |
| Hedstrom, L; Wang, CC | 1 |
| Ikegami, T; Natsumeda, Y; Weber, G; Yamada, Y | 1 |
| Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y | 1 |
| Greene, SV; Smith, JM | 1 |
| Fung, E; Hodges, SD; Lin, CC; Snyder, FF | 1 |
| Chaney, SG; Hall, IH; Holbrook, DJ; Lee, KH; Page, JD | 1 |
| Canales, J; Günther Sillero, MA; Pinto, RM; Sillero, A | 1 |
| Kokunin, VA; Kotsiuruba, AV | 1 |
| Fromont-Racine, M; Pictet, R | 1 |
| Berg, P; Chu, G | 1 |
| Clonis, YD; Lowe, CR | 1 |
| Garber, TL; Magill, CW; Magill, JM; Sabina, RL | 1 |
| Goldberg, ND; Graff, G; Moos, MC; Walseth, TF | 1 |
| Farber, DB; Kavipurapu, PR; Lolley, RN | 1 |
| Lou, L; Nakamura, J | 1 |
| Antonino, LC; Wu, JC | 1 |
| Pugh, ME; Skibo, EB | 1 |
| Hedstrom, L; Wang, W | 1 |
| Luecke, H; Prosise, GL; Whitby, FG | 1 |
| Chin, MS; Munagala, NR; Wang, CC | 1 |
| Munagala, NR; Wang, CC | 1 |
| Kollman, PA; Munagala, NR; Pitera, JW; Wang, CC | 1 |
| Borhani, DW; Héroux, A; Ross, LJ; White, EL | 1 |
| Borhani, DW; Davis, RL; Héroux, A; Ross, LJ; White, EL | 1 |
| Cahoon, M; Hedstrom, L; McMillan, FM; Petsko, GA; Ringe, D; White, A | 1 |
| Benkovic, SJ; Shim, JH; Wall, M | 1 |
| Miller, SL; Stribling, R | 1 |
| Bauer, S; Braun, KP; Budde, K; Fritsche, L; Glander, P; Hambach, P; Mai, I; Neumayer, HH; Roots, I; Waiser, J | 1 |
| Caron, PR; DeCenzo, MT; Futer, O; Livingston, DJ; Nimmesgern, E; Raybuck, SA; Sintchak, MD | 1 |
| Luecke, H; Prosise, GL | 1 |
| Kawahara, Y; Noguchi, Y; Shimba, N; Sugimoto, S; Suzuki, E | 1 |
| Cheong, CG; Greasley, SE; Wilson, IA; Wolan, DW | 1 |
| Guillén Schlippe, YV; Hedstrom, L; Riera, TV; Seyedsayamdost, MR | 1 |
| Corfù, NA; Griesser, R; Massoud, SS; Sigel, H | 1 |
| Griesser, R; Knobloch, B; Massoud, SS; Operschall, BP; Sigel, H; Song, B | 1 |
| Abbott, JL; Lam, G; Lightcap, CM; Loughlin, DT; Newell, JM; Olanich, ME; Patton, WA; Pollack, S; Weller, MA | 1 |
| Berg, A; Boitz, JM; Dobie, F; Jardim, A | 1 |
| Hedstrom, L; Josephine, HR; Riera, TV; Wang, W | 1 |
| Griesser, R; Operschall, BP; Sigel, H | 1 |
| Maiguma, T; Oishi, R; Okabe, Y; Otsubo, K; Sugitani, A; Tanaka, M; Teshima, D; Yosida, T | 1 |
| Balaram, H; Gogia, S; Puranik, M | 1 |
| Boitz, JM; Fulwiler, AL; Gilroy, C; Jardim, A; Ullman, B; Yates, PA | 1 |
| Hansen, BG; Hedstrom, L; Sun, XE | 1 |
| Beste, KY; Burhenne, H; Kaever, V; Seifert, R; Stasch, JP | 1 |
| Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R | 1 |
| Harki, DA; Hu, T; Olson, ME; Struntz, NB; White, BR | 1 |
| Chittur, SV; Davisson, VJ; Linger, RS; Oliver, JC | 1 |
| Bemer, MJ; Boeckh, MJ; Duan, H; McCune, JS; Phillips, BR; Raccor, BS; Risler, LJ; Sandmaier, BM; Storer, BE; Wang, J | 1 |
| Kawakami, J; Mino, Y; Naito, T; Ogawa, N; Shimoyama, K | 1 |
| Röttger, K; Stellmacher, R; Stuhldreier, MC; Temps, F | 1 |
| Beringer, A; Boulieu, R; Citterio-Quentin, A; Clarke, R; Gustin, C; Otero, RO; Salvi, JP | 1 |
| Anthony, S; Ji, Y; Peterson, JR | 1 |
| Doleželová, E; Guddat, LW; Hocková, D; Keough, DT; Terán, D; Zíková, A | 1 |
| Chang, CC; Liu, JL; Zhou, XL | 1 |
| Heinemann, KJ; Herde, M; Medina-Escobar, N; Rhee, S; Straube, H; Varbanova-Herde, M; Witte, CP; Yang, SY | 1 |
| Daniel, DS; Dickey, BF; Hoffenberg, S; Knoll, BJ; Nikolova, L; Pan, JY; Wessling-Resnick, M | 1 |
| Mul, YM; Rio, DC | 1 |
| Simon, MI; Yu, B | 1 |
| Alberty, RA | 1 |
1 review(s) available for xanthosine 5'-triphosphate and xanthine
| Article | Year |
|---|---|
Xanthosine 5'-monophosphate (XMP). Acid-base and metal ion-binding properties of a chameleon-like nucleotide.
Topics: Hydrogen-Ion Concentration; Metals; Nucleotides; Ribonucleotides; Xanthine | 2009 |
1 trial(s) available for xanthosine 5'-triphosphate and xanthine
| Article | Year |
|---|---|
Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.
Topics: Acute Disease; Adult; Aged; Biomarkers; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Inosine Monophosphate; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prognosis; Prospective Studies; Recurrence; Ribonucleotides; Survival Analysis; Transplantation Chimera; Transplantation, Homologous; Xanthine | 2014 |
59 other study(ies) available for xanthosine 5'-triphosphate and xanthine
| Article | Year |
|---|---|
Studies on inosine monophosphate dehydrogenase. Steady state kinetics.
Topics: Enterobacter; Guanine Nucleotides; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Lithium; NAD; Nicotinic Acids; Osmolar Concentration; Potassium; Protein Binding; Ribonucleotides; Xanthine; Xanthines | 1976 |
Interaction of metal ions withe nucleic acids. Interaction of copper(II) with xanthosine and its derivatives.
Topics: Copper; Crystallography; Magnetic Resonance Spectroscopy; Ribonucleosides; Ribonucleotides; Spectrophotometry, Infrared; Xanthine; Xanthines | 1978 |
Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
Topics: Adenine Nucleotides; Animals; Binding Sites; Binding, Competitive; IMP Dehydrogenase; Isomerism; Ketone Oxidoreductases; Kinetics; Mycophenolic Acid; NAD; Ribonucleotides; Tritrichomonas; Xanthine | 1990 |
Kinetic properties of IMP dehydrogenase purified from rat hepatoma 3924A.
Topics: Animals; Dose-Response Relationship, Drug; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Liver Neoplasms, Experimental; NAD; Rats; Ribonucleotides; Tumor Cells, Cultured; Xanthine | 1989 |
Two distinct target sites on IMP dehydrogenase in chemotherapy.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Drug Synergism; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Liver Neoplasms, Experimental; NAD; Nucleotides; Rats; Ribonucleotides; Temperature; Time Factors; Tumor Cells, Cultured; Xanthine | 1989 |
High-performance liquid chromatographic detection of XMP as a basis for an improved IMP dehydrogenase assay.
Topics: Chromatography, High Pressure Liquid; Escherichia coli; IMP Dehydrogenase; Ketone Oxidoreductases; Ribonucleotides; Xanthine | 1985 |
Increased inosinate dehydrogenase activity in mycophenolic acid resistant neuroblastoma cells.
Topics: Animals; Cell Line; Drug Resistance; IMP Dehydrogenase; Ketone Oxidoreductases; Mice; Mycophenolic Acid; Neuroblastoma; Ribonucleotides; Time Factors; Xanthine | 1986 |
Inhibition of inosine monophosphate dehydrogenase by sesquiterpene lactones.
Topics: Animals; Glutathione; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Lactones; Leukemia P388; Mycophenolic Acid; Ribonucleotides; Sesquiterpenes; Tumor Cells, Cultured; Xanthine | 1987 |
Diadenosine tetraphosphate activates cytosol 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Artemia; Cytidine Monophosphate; Cytosol; Dinucleoside Phosphates; Guanosine Monophosphate; Inosine Monophosphate; Kinetics; Nucleotidases; Rats; Ribonucleotides; Xanthine | 1986 |
[Pathways of inosine monophosphate transformation in the chicken liver].
Topics: Adenine Nucleotides; Animals; Catalysis; Chickens; Guanine Nucleotides; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Liver; Ribonucleotides; Uric Acid; Xanthine; Xanthines | 1988 |
Fast non-chromatographic method to assay for xanthine-guanosine phosphoribosyl transferase.
Topics: Kinetics; Pentosyltransferases; Ribonucleotides; Xanthine; Xanthines | 1988 |
Rapid assay for detection of Escherichia coli xanthine-guanine phosphoribosyltransferase activity in transduced cells.
Topics: Animals; Chromatography, Thin Layer; Escherichia coli; Methods; Mice; Pentosyltransferases; Ribonucleosides; Ribonucleotides; Transduction, Genetic; Xanthine; Xanthines | 1985 |
Affinity chromatography on immobilised nucleotides. The synthesis, specificity and applications of immobilised inosine 5'-monophosphate.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Affinity; Escherichia coli; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Inosine Nucleotides; Ketone Oxidoreductases; Rabbits; Ribonucleotides; Xanthine; Xanthines | 1980 |
Guanine uptake and metabolism in Neurospora crassa.
Topics: Adenine Nucleotides; Biological Transport; DNA, Fungal; Guanine; Guanine Nucleotides; Guanosine Diphosphate Sugars; Hypoxanthine Phosphoribosyltransferase; Kinetics; Neurospora; Neurospora crassa; Pentosyltransferases; Ribonucleotides; RNA; Uric Acid; Xanthine; Xanthines | 1982 |
Separation of 5'-ribonucleoside monophosphates by ion-pair reverse-phase high-performance liquid chromatography.
Topics: Adenosine Monophosphate; Chromatography, High Pressure Liquid; Cytidine Monophosphate; Guanosine Monophosphate; Indicators and Reagents; Inosine Monophosphate; Quaternary Ammonium Compounds; Ribonucleotides; Solvents; Tetraethylammonium; Tetraethylammonium Compounds; Uridine Monophosphate; Xanthine; Xanthines | 1980 |
Degradation and resynthesis of cyclic 3', 5' -guanosine monophosphate in truncated rod photoreceptors from bovine retina.
Topics: Adenosine Triphosphate; Animals; Cattle; Cyclic GMP; Guanine; Guanosine; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Photoreceptor Cells; Retina; Ribonucleotides; Rod Cell Outer Segment; Xanthine; Xanthines | 1982 |
Biochemical characterization of human GMP synthetase.
Topics: Adenosine Triphosphate; Carbon-Nitrogen Ligases; Cell Line; Humans; Isoenzymes; Kinetics; Ligases; Magnesium; Mathematics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Ribonucleotides; Substrate Specificity; Tumor Cells, Cultured; Xanthine | 1995 |
Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.
Topics: Adenosine Deaminase; Binding, Competitive; Catalysis; Chromatography, High Pressure Liquid; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Magnetic Resonance Spectroscopy; NAD; Ribonucleotides; Spectrophotometry, Ultraviolet; Xanthine | 1994 |
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: purification and properties.
Topics: Adenosine Monophosphate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Guanosine Monophosphate; Hydrogen-Ion Concentration; IMP Dehydrogenase; Inosine Monophosphate; Molecular Weight; NAD; Ribonucleotides; Swine; Thymus Gland; Xanthine | 1993 |
Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
Topics: Humans; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Molecular Structure; NAD; Oxidation-Reduction; Ribonucleotides; Spectrometry, Fluorescence; Substrate Specificity; Xanthine | 1997 |
Tritrichomonas foetus: a strategy for structure-based inhibitor design of a protozoan inosine-5'-monophosphate dehydrogenase.
Topics: Animals; Antiprotozoal Agents; Binding Sites; Computer Simulation; Crystallography; Drug Design; IMP Dehydrogenase; Models, Molecular; Protein Conformation; Research Design; Ribonucleotides; Tritrichomonas foetus; Xanthine | 1997 |
Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Guanosine Monophosphate; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Ribonucleotides; Threonine; Tritrichomonas foetus; Xanthine | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment.
Topics: Animals; Computer Simulation; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Pentosyltransferases; Protein Conformation; Ribonucleotides; Software; Substrate Specificity; Thermodynamics; Tritrichomonas foetus; Xanthine | 1999 |
Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Quaternary; Recombinant Proteins; Ribonucleotides; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Toxoplasma; Xanthine | 1999 |
Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.
Topics: Animals; Base Sequence; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diphosphates; DNA Primers; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleotides; Toxoplasma; Xanthine | 1999 |
Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
Topics: Amino Acid Sequence; Animals; Binding Sites; Borrelia burgdorferi Group; Catalytic Domain; Crystallography, X-Ray; Cysteine; Drug Design; Humans; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Motion; NAD; Pliability; Protein Conformation; Ribonucleotides; Sequence Alignment; Solvents; Static Electricity; Structure-Activity Relationship; Sulfates; Xanthine | 2000 |
Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis.
Topics: Adenosine Monophosphate; Amides; Aminoimidazole Carboxamide; Binding Sites; Biological Transport; Catalysis; Enzyme Inhibitors; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Multienzyme Complexes; Nucleotide Deaminases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Protein Conformation; Ribonucleosides; Ribonucleotides; Xanthine | 2000 |
Attempted nonenzymatic template-directed oligomerizations on a polyadenylic acid template: implications for the nature of the first genetic material.
Topics: Evolution, Molecular; Hydrogen-Ion Concentration; Oligonucleotides; Origin of Life; Phosphorylation; Poly A; Purines; Pyrimidines; Quinazolines; Ribonucleotides; Temperature; Templates, Genetic; Uracil; Uridine Monophosphate; Xanthine | 1991 |
Non-radioactive determination of inosine 5'-monophosphate dehydro-genase (IMPDH) in peripheral mononuclear cells.
Topics: Adult; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Humans; IMP Dehydrogenase; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Reproducibility of Results; Ribonucleotides; Xanthine | 2001 |
A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.
Topics: Binding Sites; Catalysis; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; NAD; Ribonucleotides; Xanthine | 2002 |
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine | 2003 |
31P NMR studies of energy metabolism in xanthosine-5'-monophosphate overproducing Corynebacterium ammoniagenes.
Topics: Adenine Nucleotides; Corynebacterium; Energy Metabolism; Escherichia coli; Glutamic Acid; Hypoxanthine; Kinetics; Magnetic Resonance Spectroscopy; Phosphorus; Ribonucleotides; Xanthine | 2003 |
Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.
Topics: Amino Acid Sequence; Aminoimidazole Carboxamide; Animals; Apoenzymes; Binding Sites; Birds; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Hydroxymethyl and Formyl Transferases; IMP Dehydrogenase; Molecular Sequence Data; Nucleic Acid Conformation; Nucleotide Deaminases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Protein Conformation; Recombinant Proteins; Ribonucleotides; Xanthine | 2004 |
Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.
Topics: Adenosine Diphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Cattle; Conserved Sequence; Deuterium Exchange Measurement; Enzyme Inhibitors; Hydrolysis; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Mycophenolic Acid; Phenylalanine; Point Mutation; Protein Binding; Ribavirin; Ribonucleosides; Ribonucleotides; Solvents; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 2004 |
Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.
Topics: Acids; Alkalies; Hydrogen; Hydrogen-Ion Concentration; Isomerism; Molecular Structure; Nitrogen; Protons; Ribonucleotides; Solutions; Xanthine | 2004 |
Acid-base and metal-ion-binding properties of xanthosine 5'-monophosphate (XMP) in aqueous solution: complex stabilities, isomeric equilibria, and extent of macrochelation.
Topics: Acids; Alkalies; Chelating Agents; Hydrogen-Ion Concentration; Ions; Metals; Potentiometry; Ribonucleotides; Solubility; Solutions; Stereoisomerism; Water; Xanthine | 2006 |
The effects of removing the GAT domain from E. coli GMP synthetase.
Topics: Adenosine Triphosphate; Ammonia; Carbon-Nitrogen Ligases; Cloning, Molecular; Dimerization; Escherichia coli; Escherichia coli Proteins; Kinetics; Protein Conformation; Protein Structure, Tertiary; Pyrophosphatases; Recombinant Proteins; Ribonucleotides; Solutions; Xanthine | 2006 |
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine | 2007 |
A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cryptosporidium parvum; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NAD; Protein Binding; Ribonucleotides; Xanthine | 2008 |
Evaluation of inosin-5'-monophosphate dehydrogenase activity during maintenance therapy with tacrolimus.
Topics: Adult; Biomarkers, Pharmacological; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Kidney Transplantation; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prodrugs; Reproducibility of Results; Ribonucleotides; Tacrolimus; Xanthine; Young Adult | 2010 |
Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Topics: Animals; Catalytic Domain; Deuterium Exchange Measurement; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Plasmodium falciparum; Protein Binding; Purine Nucleotides; Ribonucleotides; Spectrum Analysis, Raman; Substrate Specificity; Toxoplasma; Xanthine | 2011 |
IMP dehydrogenase deficiency in Leishmania donovani causes a restrictive growth phenotype in promastigotes but is not essential for infection in mice.
Topics: Animals; Guanosine Monophosphate; Humans; IMP Dehydrogenase; Leishmania donovani; Leishmania infantum; Mice; Mice, Inbred BALB C; Phenotype; Protozoan Proteins; Ribonucleotides; Xanthine | 2011 |
Kinetically controlled drug resistance: how Penicillium brevicompactum survives mycophenolic acid.
Topics: Animals; Cricetinae; Drug Resistance, Fungal; Enzyme Inhibitors; IMP Dehydrogenase; Kinetics; Models, Molecular; Mycophenolic Acid; Penicillium; Protein Conformation; Ribonucleotides; Xanthine | 2011 |
Nucleotidyl cyclase activity of soluble guanylyl cyclase α1β1.
Topics: Animals; Cattle; Cyclic AMP; Cyclic CMP; Cyclic GMP; Cyclic IMP; Guanylate Cyclase; Humans; Isoenzymes; Ligases; Rats; Receptors, Cytoplasmic and Nuclear; Ribonucleotides; Solubility; Soluble Guanylyl Cyclase; Substrate Specificity; Xanthine | 2012 |
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine | 2012 |
Inhibition of guanosine monophosphate synthetase by the substrate enantiomer L-XMP.
Topics: Catalytic Domain; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Ligases; Models, Molecular; Ribonucleotides; Stereoisomerism; Xanthine | 2012 |
Substrate activation and conformational dynamics of guanosine 5'-monophosphate synthetase.
Topics: Carbon-Nitrogen Ligases; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Catalytic Domain; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Guanosine Monophosphate; Kinetics; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Ribonucleotides; Substrate Specificity; Xanthine | 2013 |
Mycophenolic acid exposure and complement fraction C3 influence inosine 5'-monophosphate dehydrogenase activity in systemic lupus erythematosus.
Topics: Adult; Body Weight; Complement C3; Cross-Sectional Studies; Drug Administration Schedule; Female; Glucuronides; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Lupus Erythematosus, Systemic; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Remission Induction; Ribonucleotides; Xanthine | 2017 |
Ultrafast Electronic Deactivation Dynamics of Xanthosine Monophosphate.
Topics: Adenine; Electrons; Guanine; Kinetics; Light; Photochemical Processes; Protons; Ribonucleotides; Spectrometry, Fluorescence; Thermodynamics; Xanthine | 2017 |
Determination of inosine 5'-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; IMP Dehydrogenase; Linear Models; Male; Middle Aged; Purines; Reproducibility of Results; Ribonucleotides; Xanthine; Young Adult | 2017 |
Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.
Topics: Animals; Biological Assay; Humans; IMP Dehydrogenase; Inosine Monophosphate; NAD; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides; Xanthine | 2017 |
Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP.
Topics: Amino Acid Sequence; Guanosine Monophosphate; Inosine Monophosphate; Pentosyltransferases; Protein Conformation; Ribonucleotides; Substrate Specificity; Trypanosoma brucei brucei; Xanthine | 2019 |
Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic β Cells.
Topics: Animals; Biocatalysis; Cell Line, Tumor; Cells, Cultured; Cytoplasmic Granules; Fluorescent Antibody Technique; Humans; IMP Dehydrogenase; Inosine Monophosphate; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Multimerization; Ribonucleotides; Xanthine | 2021 |
Initiation of cytosolic plant purine nucleotide catabolism involves a monospecific xanthosine monophosphate phosphatase.
Topics: Arabidopsis; Arabidopsis Proteins; Cytosol; Models, Molecular; Mutation; Phosphoric Monoester Hydrolases; Phylogeny; Plants; Purine Nucleotides; Ribonucleotides; Substrate Specificity; Xanthine | 2021 |
Functional and structural interactions of the Rab5 D136N mutant with xanthine nucleotides.
Topics: Base Sequence; Escherichia coli; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Protein Prenylation; rab5 GTP-Binding Proteins; Recombinant Proteins; Ribonucleotides; Trypsin; Xanthine; Xanthines | 1995 |
Reprogramming the purine nucleotide cofactor requirement of Drosophila P element transposase in vivo.
Topics: Animals; Cell Line; Consensus Sequence; DNA Nucleotidyltransferases; DNA Transposable Elements; Drosophila; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Immunoblotting; Mutation; Plasmids; Protein Binding; Ribonucleosides; Ribonucleotides; Transposases; Xanthine; Xanthines | 1997 |
Interaction of the xanthine nucleotide binding Goalpha mutant with G protein-coupled receptors.
Topics: Animals; Cattle; COS Cells; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nucleotides; Receptor, Muscarinic M2; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Muscarinic; Receptors, Peptide; Ribonucleotides; Spodoptera; Thionucleotides; Xanthine; Xanthines | 1998 |
Thermodynamic properties of enzyme-catalyzed reactions involving guanine, xanthine, and their nucleosides and nucleotides.
Topics: Catalysis; Databases, Factual; Enzymes; Guanine; Guanine Nucleotides; Guanosine Triphosphate; Hydrogen-Ion Concentration; Hypoxanthines; Nucleosides; Osmolar Concentration; Ribonucleotides; Solutions; Thermodynamics; Water; Xanthine | 2006 |