Compounds > xanthosine 5'-triphosphate

xanthosine 5'-triphosphate and inosinic acid

xanthosine 5'-triphosphate has been researched along with inosinic acid in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's5 (22.73)18.2507
2000's5 (22.73)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Ikegami, T; Natsumeda, Y; Weber, G; Yamada, Y1
Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y1
Canales, J; Günther Sillero, MA; Pinto, RM; Sillero, A1
Kokunin, VA; Kotsiuruba, AV1
Clonis, YD; Lowe, CR1
Goldberg, ND; Graff, G; Moos, MC; Walseth, TF1
Antonino, LC; Wu, JC1
Pugh, ME; Skibo, EB1
Hedstrom, L; Wang, W1
Chin, MS; Munagala, NR; Wang, CC1
Borhani, DW; Héroux, A; Ross, LJ; White, EL1
Cahoon, M; Hedstrom, L; McMillan, FM; Petsko, GA; Ringe, D; White, A1
Caron, PR; DeCenzo, MT; Futer, O; Livingston, DJ; Nimmesgern, E; Raybuck, SA; Sintchak, MD1
Luecke, H; Prosise, GL1
Berg, A; Boitz, JM; Dobie, F; Jardim, A1
Hedstrom, L; Josephine, HR; Riera, TV; Wang, W1
Balaram, H; Gogia, S; Puranik, M1
Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R1
Bemer, MJ; Boeckh, MJ; Duan, H; McCune, JS; Phillips, BR; Raccor, BS; Risler, LJ; Sandmaier, BM; Storer, BE; Wang, J1
Anthony, S; Ji, Y; Peterson, JR1
Doleželová, E; Guddat, LW; Hocková, D; Keough, DT; Terán, D; Zíková, A1
Chang, CC; Liu, JL; Zhou, XL1

Trials

1 trial(s) available for xanthosine 5'-triphosphate and inosinic acid

ArticleYear
Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:10

    Topics: Acute Disease; Adult; Aged; Biomarkers; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Inosine Monophosphate; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prognosis; Prospective Studies; Recurrence; Ribonucleotides; Survival Analysis; Transplantation Chimera; Transplantation, Homologous; Xanthine

2014

Other Studies

21 other study(ies) available for xanthosine 5'-triphosphate and inosinic acid

ArticleYear
Kinetic properties of IMP dehydrogenase purified from rat hepatoma 3924A.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Animals; Dose-Response Relationship, Drug; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Liver Neoplasms, Experimental; NAD; Rats; Ribonucleotides; Tumor Cells, Cultured; Xanthine

1989
Two distinct target sites on IMP dehydrogenase in chemotherapy.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Drug Synergism; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Liver Neoplasms, Experimental; NAD; Nucleotides; Rats; Ribonucleotides; Temperature; Time Factors; Tumor Cells, Cultured; Xanthine

1989
Diadenosine tetraphosphate activates cytosol 5'-nucleotidase.
    Biochemical and biophysical research communications, 1986, Jul-16, Volume: 138, Issue:1

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Artemia; Cytidine Monophosphate; Cytosol; Dinucleoside Phosphates; Guanosine Monophosphate; Inosine Monophosphate; Kinetics; Nucleotidases; Rats; Ribonucleotides; Xanthine

1986
[Pathways of inosine monophosphate transformation in the chicken liver].
    Biokhimiia (Moscow, Russia), 1988, Volume: 53, Issue:2

    Topics: Adenine Nucleotides; Animals; Catalysis; Chickens; Guanine Nucleotides; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Liver; Ribonucleotides; Uric Acid; Xanthine; Xanthines

1988
Affinity chromatography on immobilised nucleotides. The synthesis, specificity and applications of immobilised inosine 5'-monophosphate.
    European journal of biochemistry, 1980, Volume: 110, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Affinity; Escherichia coli; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Inosine Nucleotides; Ketone Oxidoreductases; Rabbits; Ribonucleotides; Xanthine; Xanthines

1980
Separation of 5'-ribonucleoside monophosphates by ion-pair reverse-phase high-performance liquid chromatography.
    Analytical biochemistry, 1980, Sep-01, Volume: 107, Issue:1

    Topics: Adenosine Monophosphate; Chromatography, High Pressure Liquid; Cytidine Monophosphate; Guanosine Monophosphate; Indicators and Reagents; Inosine Monophosphate; Quaternary Ammonium Compounds; Ribonucleotides; Solvents; Tetraethylammonium; Tetraethylammonium Compounds; Uridine Monophosphate; Xanthine; Xanthines

1980
Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.
    Biochemistry, 1994, Feb-22, Volume: 33, Issue:7

    Topics: Adenosine Deaminase; Binding, Competitive; Catalysis; Chromatography, High Pressure Liquid; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Magnetic Resonance Spectroscopy; NAD; Ribonucleotides; Spectrophotometry, Ultraviolet; Xanthine

1994
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: purification and properties.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1993, Volume: 105, Issue:2

    Topics: Adenosine Monophosphate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Guanosine Monophosphate; Hydrogen-Ion Concentration; IMP Dehydrogenase; Inosine Monophosphate; Molecular Weight; NAD; Ribonucleotides; Swine; Thymus Gland; Xanthine

1993
Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
    Biochemistry, 1997, Jul-15, Volume: 36, Issue:28

    Topics: Humans; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Molecular Structure; NAD; Oxidation-Reduction; Ribonucleotides; Spectrometry, Fluorescence; Substrate Specificity; Xanthine

1997
Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
    Biochemistry, 1998, Mar-24, Volume: 37, Issue:12

    Topics: Amino Acid Substitution; Animals; Binding, Competitive; Guanosine Monophosphate; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Ribonucleotides; Threonine; Tritrichomonas foetus; Xanthine

1998
Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.
    Biochemistry, 1999, Nov-02, Volume: 38, Issue:44

    Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Quaternary; Recombinant Proteins; Ribonucleotides; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Toxoplasma; Xanthine

1999
Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Amino Acid Sequence; Animals; Binding Sites; Borrelia burgdorferi Group; Catalytic Domain; Crystallography, X-Ray; Cysteine; Drug Design; Humans; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Motion; NAD; Pliability; Protein Conformation; Ribonucleotides; Sequence Alignment; Solvents; Static Electricity; Structure-Activity Relationship; Sulfates; Xanthine

2000
A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.
    Biochimica et biophysica acta, 2002, Jan-31, Volume: 1594, Issue:1

    Topics: Binding Sites; Catalysis; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; NAD; Ribonucleotides; Xanthine

2002
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Journal of molecular biology, 2003, Feb-14, Volume: 326, Issue:2

    Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine

2003
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
    Molecular and biochemical parasitology, 2007, Volume: 152, Issue:1

    Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine

2007
A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.
    Biochemistry, 2008, Aug-19, Volume: 47, Issue:33

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cryptosporidium parvum; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NAD; Protein Binding; Ribonucleotides; Xanthine

2008
Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
    Biochemistry, 2011, May-17, Volume: 50, Issue:19

    Topics: Animals; Catalytic Domain; Deuterium Exchange Measurement; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Plasmodium falciparum; Protein Binding; Purine Nucleotides; Ribonucleotides; Spectrum Analysis, Raman; Substrate Specificity; Toxoplasma; Xanthine

2011
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
    Biochemistry, 2012, Aug-07, Volume: 51, Issue:31

    Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine

2012
Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1608

    Topics: Animals; Biological Assay; Humans; IMP Dehydrogenase; Inosine Monophosphate; NAD; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides; Xanthine

2017
Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP.
    The FEBS journal, 2019, Volume: 286, Issue:23

    Topics: Amino Acid Sequence; Guanosine Monophosphate; Inosine Monophosphate; Pentosyltransferases; Protein Conformation; Ribonucleotides; Substrate Specificity; Trypanosoma brucei brucei; Xanthine

2019
Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic β Cells.
    Pancreas, 2021, 08-01, Volume: 50, Issue:7

    Topics: Animals; Biocatalysis; Cell Line, Tumor; Cells, Cultured; Cytoplasmic Granules; Fluorescent Antibody Technique; Humans; IMP Dehydrogenase; Inosine Monophosphate; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Multimerization; Ribonucleotides; Xanthine

2021