xanthine and mycophenolic acid

xanthine has been researched along with mycophenolic acid in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's3 (15.79)18.2507
2000's6 (31.58)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auschwitz, JM; Dubey, JP; Ferreira, LR; Fomovska, A; Hickman, MR; Lee, PJ; Leed, SE; McLeod, R; Mui, E; Roberts, C; Sommerville, C; Welsh, WJ; Wood, RD; Woods, S1
Alexiou, M; Leese, HJ1
Cheung, KS; Hedstrom, L; Wang, CC1
Hedstrom, L; Wang, CC1
Fung, E; Hodges, SD; Lin, CC; Snyder, FF1
Chaney, SG; Hall, IH; Holbrook, DJ; Lee, KH; Page, JD1
Hoshi, M; Mizuno, A; Yuki, A1
Farley, BA; Ohlsson-Wilhelm, BM; Rowley, PT; Rudolph, NS1
Bauer, S; Braun, KP; Budde, K; Fritsche, L; Glander, P; Hambach, P; Mai, I; Neumayer, HH; Roots, I; Waiser, J1
Luecke, H; Prosise, GL1
Guillén Schlippe, YV; Hedstrom, L; Riera, TV; Seyedsayamdost, MR1
Athias, P; Bès, S; Rochette, L; Tatou, E; Tissier, C; Vandroux, D1
Berg, A; Boitz, JM; Dobie, F; Jardim, A1
Chakraborty, U; Foley, JP; Zhang, J1
Maiguma, T; Oishi, R; Okabe, Y; Otsubo, K; Sugitani, A; Tanaka, M; Teshima, D; Yosida, T1
Hansen, BG; Hedstrom, L; Sun, XE1
Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R1
Bemer, MJ; Boeckh, MJ; Duan, H; McCune, JS; Phillips, BR; Raccor, BS; Risler, LJ; Sandmaier, BM; Storer, BE; Wang, J1
Kawakami, J; Mino, Y; Naito, T; Ogawa, N; Shimoyama, K1

Trials

1 trial(s) available for xanthine and mycophenolic acid

ArticleYear
Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:10

    Topics: Acute Disease; Adult; Aged; Biomarkers; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Inosine Monophosphate; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prognosis; Prospective Studies; Recurrence; Ribonucleotides; Survival Analysis; Transplantation Chimera; Transplantation, Homologous; Xanthine

2014

Other Studies

18 other study(ies) available for xanthine and mycophenolic acid

ArticleYear
Salicylanilide inhibitors of Toxoplasma gondii.
    Journal of medicinal chemistry, 2012, Oct-11, Volume: 55, Issue:19

    Topics: Animals; Antimalarials; Antiparasitic Agents; Cells, Cultured; Drug Resistance; Female; Fibroblasts; Humans; Mice; Mice, Transgenic; Plasmodium falciparum; Salicylanilides; Structure-Activity Relationship; Toxoplasma; Toxoplasmosis

2012
Purine utilisation, de novo synthesis and degradation in mouse preimplantation embryos.
    Development (Cambridge, England), 1992, Volume: 114, Issue:1

    Topics: Adenine; Animals; Azaserine; Blastocyst; Cells, Cultured; Chromatography, High Pressure Liquid; Guanine; Hypoxanthines; Mice; Mice, Inbred Strains; Mycophenolic Acid; Purines; Xanthine; Xanthines

1992
A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Adenine; Animals; Cloning, Molecular; Drug Resistance; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Mutation; Mycophenolic Acid; Tritrichomonas; Xanthine; Xanthines

1990
Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
    Biochemistry, 1990, Jan-30, Volume: 29, Issue:4

    Topics: Adenine Nucleotides; Animals; Binding Sites; Binding, Competitive; IMP Dehydrogenase; Isomerism; Ketone Oxidoreductases; Kinetics; Mycophenolic Acid; NAD; Ribonucleotides; Tritrichomonas; Xanthine

1990
Increased inosinate dehydrogenase activity in mycophenolic acid resistant neuroblastoma cells.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Animals; Cell Line; Drug Resistance; IMP Dehydrogenase; Ketone Oxidoreductases; Mice; Mycophenolic Acid; Neuroblastoma; Ribonucleotides; Time Factors; Xanthine

1986
Inhibition of inosine monophosphate dehydrogenase by sesquiterpene lactones.
    Biochimica et biophysica acta, 1987, Nov-06, Volume: 926, Issue:2

    Topics: Animals; Glutathione; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Lactones; Leukemia P388; Mycophenolic Acid; Ribonucleotides; Sesquiterpenes; Tumor Cells, Cultured; Xanthine

1987
Restoration by xanthine of development of mouse embryos inhibited by mycophenolic acid.
    Journal of reproduction and fertility, 1988, Volume: 83, Issue:1

    Topics: Animals; Blastocyst; Cells, Cultured; Embryo Transfer; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mycophenolic Acid; Xanthine; Xanthines

1988
Erythroid induction of K562 human leukemia cells: enhancement by purines.
    Archives of biochemistry and biophysics, 1985, Volume: 239, Issue:2

    Topics: Adenine; Cell Cycle; Cell Division; Cell Line; Drug Synergism; Guanine; Hemoglobins; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Mycophenolic Acid; Thymidine; Xanthine; Xanthines

1985
Non-radioactive determination of inosine 5'-monophosphate dehydro-genase (IMPDH) in peripheral mononuclear cells.
    Clinical biochemistry, 2001, Volume: 34, Issue:7

    Topics: Adult; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Humans; IMP Dehydrogenase; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Reproducibility of Results; Ribonucleotides; Xanthine

2001
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Journal of molecular biology, 2003, Feb-14, Volume: 326, Issue:2

    Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine

2003
Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.
    Biochemistry, 2004, Apr-20, Volume: 43, Issue:15

    Topics: Adenosine Diphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Cattle; Conserved Sequence; Deuterium Exchange Measurement; Enzyme Inhibitors; Hydrolysis; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Mycophenolic Acid; Phenylalanine; Point Mutation; Protein Binding; Ribavirin; Ribonucleosides; Ribonucleotides; Solvents; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine

2004
Physiological and metabolic actions of mycophenolate mofetil on cultured newborn rat cardiomyocytes in normoxia and in simulated ischemia.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:3

    Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Hypoxanthine; Immunosuppressive Agents; Membrane Potentials; Mycophenolic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocytes, Cardiac; Rats; Rats, Wistar; Xanthine

2004
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
    Molecular and biochemical parasitology, 2007, Volume: 152, Issue:1

    Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine

2007
Determination of residual cell culture media components by MEKC.
    Electrophoresis, 2009, Volume: 30, Issue:22

    Topics: Chromatography, Micellar Electrokinetic Capillary; Culture Media; Folic Acid; Hydrogen-Ion Concentration; Hypoxanthine; Limit of Detection; Mycophenolic Acid; Niacin; Reproducibility of Results; Riboflavin; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Xanthine

2009
Evaluation of inosin-5'-monophosphate dehydrogenase activity during maintenance therapy with tacrolimus.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:1

    Topics: Adult; Biomarkers, Pharmacological; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Kidney Transplantation; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prodrugs; Reproducibility of Results; Ribonucleotides; Tacrolimus; Xanthine; Young Adult

2010
Kinetically controlled drug resistance: how Penicillium brevicompactum survives mycophenolic acid.
    The Journal of biological chemistry, 2011, Nov-25, Volume: 286, Issue:47

    Topics: Animals; Cricetinae; Drug Resistance, Fungal; Enzyme Inhibitors; IMP Dehydrogenase; Kinetics; Models, Molecular; Mycophenolic Acid; Penicillium; Protein Conformation; Ribonucleotides; Xanthine

2011
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
    Biochemistry, 2012, Aug-07, Volume: 51, Issue:31

    Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine

2012
Mycophenolic acid exposure and complement fraction C3 influence inosine 5'-monophosphate dehydrogenase activity in systemic lupus erythematosus.
    Annals of clinical biochemistry, 2017, Volume: 54, Issue:4

    Topics: Adult; Body Weight; Complement C3; Cross-Sectional Studies; Drug Administration Schedule; Female; Glucuronides; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Lupus Erythematosus, Systemic; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Remission Induction; Ribonucleotides; Xanthine

2017