xanthine and mercaptopurine

xanthine has been researched along with mercaptopurine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T1
Al-Safi, SA; Maddocks, JL1
Bökkerink, JP; DeAbreu, RA; Keuzenkamp-Jansen, CW; Lambooy, MA; Trijbels, JM1
BRASCHI, A; CERRI, O1
Jena, G; Kalra, S; Mukhopadhyay, AK; Tikoo, K1
Krijt, J; Pavelcova, K; Petru, L; Stiburkova, B1
Fliszár-Nyúl, E; Mohos, V; Poór, M1

Trials

1 trial(s) available for xanthine and mercaptopurine

ArticleYear
Metabolism of intravenously administered high-dose 6-mercaptopurine with and without allopurinol treatment in patients with non-Hodgkin lymphoma.
    Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:2

    Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypoxanthine; Hypoxanthines; Individuality; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methylthioinosine; Nucleotides; Xanthine; Xanthine Oxidase; Xanthines

1996

Other Studies

6 other study(ies) available for xanthine and mercaptopurine

ArticleYear
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship

2006
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:4

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines

1984
[Spectrophotometric determination of a mixture of hypoxanthine, xanthine, uric acid & 6-mercaptopurine].
    Bollettino chimico farmaceutico, 1957, Volume: 96, Issue:4

    Topics: Humans; Hypoxanthine; Hypoxanthines; Mercaptopurine; Spectrophotometry; Uric Acid; Xanthine; Xanthines

1957
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.
    BMC biochemistry, 2007, May-18, Volume: 8

    Topics: Adenine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Kinetics; Mercaptopurine; Models, Chemical; Molecular Structure; Substrate Specificity; Thioguanine; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

2007
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II).
    Toxicology and applied pharmacology, 2018, 08-15, Volume: 353

    Topics: Adult; Aldehyde Oxidase; Female; Humans; Mercaptopurine; Methyltransferases; Polymorphism, Genetic; Purine-Pyrimidine Metabolism, Inborn Errors; Sulfurtransferases; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase

2018
Inhibition of Xanthine Oxidase-Catalyzed Xanthine and 6-Mercaptopurine Oxidation by Flavonoid Aglycones and Some of Their Conjugates.
    International journal of molecular sciences, 2020, May-05, Volume: 21, Issue:9

    Topics: Allopurinol; Catalysis; Dose-Response Relationship, Drug; Flavonoids; Mercaptopurine; Oxidation-Reduction; Xanthine; Xanthine Oxidase

2020