xanthine has been researched along with inosinic acid in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (38.24) | 18.7374 |
| 1990's | 10 (29.41) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Coumans, WA; de Groot, MJ; van der Vusse, GJ | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| Ikegami, T; Natsumeda, Y; Weber, G; Yamada, Y | 1 |
| Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y | 1 |
| Demin, VF; Pimenov, AM; Toguzov, RT | 1 |
| Fox, IH; Tekkanat, KK | 1 |
| Canales, J; Günther Sillero, MA; Pinto, RM; Sillero, A | 1 |
| Coumans, WA; Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M | 1 |
| Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M | 1 |
| Gavin, JB; Humphrey, SM; Vanderwee, MA | 1 |
| Kokunin, VA; Kotsiuruba, AV | 1 |
| Armiger, LC; Hollis, DG; Seelye, RN | 1 |
| Pimenov, AM; Prokudin, VIu; Sitnikov, VF; Tikhonov, IuV; Toguzov, RT | 1 |
| Clonis, YD; Lowe, CR | 1 |
| Goldberg, ND; Graff, G; Moos, MC; Walseth, TF | 1 |
| Antonino, LC; Wu, JC | 1 |
| Pugh, ME; Skibo, EB | 1 |
| Hedstrom, L; Wang, W | 1 |
| Chin, MS; Munagala, NR; Wang, CC | 1 |
| Hayakawa, Y; Masaoka, N; Ohgame, S; Sakata, H; Satoh, K; Takahashi, H | 1 |
| Essén-Gustavsson, B; Schuback, K | 1 |
| Sahlin, K; Söderlund, K; Tonkonogi, M | 1 |
| Borhani, DW; Héroux, A; Ross, LJ; White, EL | 1 |
| Cahoon, M; Hedstrom, L; McMillan, FM; Petsko, GA; Ringe, D; White, A | 1 |
| Caron, PR; DeCenzo, MT; Futer, O; Livingston, DJ; Nimmesgern, E; Raybuck, SA; Sintchak, MD | 1 |
| Luecke, H; Prosise, GL | 1 |
| Berg, A; Boitz, JM; Dobie, F; Jardim, A | 1 |
| Hedstrom, L; Josephine, HR; Riera, TV; Wang, W | 1 |
| Balaram, H; Gogia, S; Puranik, M | 1 |
| Anderson, WF; Binkowski, TA; Gollapalli, DR; Gornicki, P; Hedstrom, L; Jedrzejczak, R; Joachimiak, A; Kim, Y; Kuhn, ML; Mack, JC; Makowska-Grzyska, M; Maltseva, N; Mulligan, R; Wang, XK; Wilton, R; Wu, R; Zhang, R | 1 |
| Bemer, MJ; Boeckh, MJ; Duan, H; McCune, JS; Phillips, BR; Raccor, BS; Risler, LJ; Sandmaier, BM; Storer, BE; Wang, J | 1 |
| Anthony, S; Ji, Y; Peterson, JR | 1 |
| Doleželová, E; Guddat, LW; Hocková, D; Keough, DT; Terán, D; Zíková, A | 1 |
| Chang, CC; Liu, JL; Zhou, XL | 1 |
1 trial(s) available for xanthine and inosinic acid
| Article | Year |
|---|---|
Recipient pretransplant inosine monophosphate dehydrogenase activity in nonmyeloablative hematopoietic cell transplantation.
Topics: Acute Disease; Adult; Aged; Biomarkers; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Inosine Monophosphate; Leukocytes, Mononuclear; Male; Middle Aged; Mycophenolic Acid; Prognosis; Prospective Studies; Recurrence; Ribonucleotides; Survival Analysis; Transplantation Chimera; Transplantation, Homologous; Xanthine | 2014 |
33 other study(ies) available for xanthine and inosinic acid
| Article | Year |
|---|---|
The nucleotide metabolism in lactate perfused hearts under ischaemic and reperfused conditions.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Guanosine Triphosphate; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphocreatine; Pyruvates; Rats; Rats, Inbred Lew; Time Factors; Xanthine; Xanthines | 1992 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
Kinetic properties of IMP dehydrogenase purified from rat hepatoma 3924A.
Topics: Animals; Dose-Response Relationship, Drug; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Liver Neoplasms, Experimental; NAD; Rats; Ribonucleotides; Tumor Cells, Cultured; Xanthine | 1989 |
Two distinct target sites on IMP dehydrogenase in chemotherapy.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Drug Synergism; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Liver Neoplasms, Experimental; NAD; Nucleotides; Rats; Ribonucleotides; Temperature; Time Factors; Tumor Cells, Cultured; Xanthine | 1989 |
Influence of perinatal hypoxia on purine contents in erythrocytes of newborn infants.
Topics: Asphyxia Neonatorum; Erythrocytes; Female; Fetal Blood; Fetal Hypoxia; Humans; Hypoxanthine; Hypoxanthines; Infant, Newborn; Inosine Monophosphate; Pregnancy; Purines; Reference Values; Uric Acid; Xanthine; Xanthines | 1989 |
Isocratic separation of ATP and its degradation products from biological fluids by automated liquid chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Autoanalysis; Body Fluids; Chromatography, Liquid; Cyclic AMP; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Xanthine; Xanthines | 1988 |
Diadenosine tetraphosphate activates cytosol 5'-nucleotidase.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Artemia; Cytidine Monophosphate; Cytosol; Dinucleoside Phosphates; Guanosine Monophosphate; Inosine Monophosphate; Kinetics; Nucleotidases; Rats; Ribonucleotides; Xanthine | 1986 |
Assessment of warm ischemia time in donor kidneys by analysis of purine metabolism.
Topics: Adenine Nucleotides; Animals; Dogs; Female; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Ischemia; Kidney; Kidney Cortex; Kinetics; Male; Purines; Temperature; Xanthine; Xanthines | 1987 |
Nucleotides, nucleosides, and oxypurines in human kidneys measured by use of reversed-phase high-performance liquid chromatography.
Topics: Adenine Nucleotides; Adenosine; Chromatography, High Pressure Liquid; Coenzyme A; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Kidney Cortex; Kidney Transplantation; NAD; NADP; Nucleosides; Nucleotides; Quality Control; Xanthine; Xanthines | 1988 |
Transmural differences in the postischemic recovery of cardiac energy metabolism.
Topics: Adenine Nucleotides; Animals; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Reference Values; Uric Acid; Xanthine; Xanthines | 1988 |
[Pathways of inosine monophosphate transformation in the chicken liver].
Topics: Adenine Nucleotides; Animals; Catalysis; Chickens; Guanine Nucleotides; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Liver; Ribonucleotides; Uric Acid; Xanthine; Xanthines | 1988 |
Regional variations in the "adenine/oxypurine" pool of the heart in normoxia and oxygen deficiency.
Topics: Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Dogs; Energy Metabolism; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine Monophosphate; Male; Myocardium; NAD; Uric Acid; Xanthine; Xanthines | 1986 |
[Destruction of muscle tissue and purine compound metabolism in hereditary muscular dystrophy].
Topics: Adenine Nucleotides; Animals; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Muscles; Muscular Dystrophies; Purines; Uric Acid; Xanthine; Xanthines | 1986 |
Affinity chromatography on immobilised nucleotides. The synthesis, specificity and applications of immobilised inosine 5'-monophosphate.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Affinity; Escherichia coli; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Inosine Nucleotides; Ketone Oxidoreductases; Rabbits; Ribonucleotides; Xanthine; Xanthines | 1980 |
Separation of 5'-ribonucleoside monophosphates by ion-pair reverse-phase high-performance liquid chromatography.
Topics: Adenosine Monophosphate; Chromatography, High Pressure Liquid; Cytidine Monophosphate; Guanosine Monophosphate; Indicators and Reagents; Inosine Monophosphate; Quaternary Ammonium Compounds; Ribonucleotides; Solvents; Tetraethylammonium; Tetraethylammonium Compounds; Uridine Monophosphate; Xanthine; Xanthines | 1980 |
Human IMP dehydrogenase catalyzes the dehalogenation of 2-fluoro- and 2-chloroinosine 5'-monophosphate in the absence of NAD.
Topics: Adenosine Deaminase; Binding, Competitive; Catalysis; Chromatography, High Pressure Liquid; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Magnetic Resonance Spectroscopy; NAD; Ribonucleotides; Spectrophotometry, Ultraviolet; Xanthine | 1994 |
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: purification and properties.
Topics: Adenosine Monophosphate; Amino Acids; Animals; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Guanosine Monophosphate; Hydrogen-Ion Concentration; IMP Dehydrogenase; Inosine Monophosphate; Molecular Weight; NAD; Ribonucleotides; Swine; Thymus Gland; Xanthine | 1993 |
Kinetic mechanism of human inosine 5'-monophosphate dehydrogenase type II: random addition of substrates and ordered release of products.
Topics: Humans; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Molecular Structure; NAD; Oxidation-Reduction; Ribonucleotides; Spectrometry, Fluorescence; Substrate Specificity; Xanthine | 1997 |
Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Guanosine Monophosphate; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Ribonucleotides; Threonine; Tritrichomonas foetus; Xanthine | 1998 |
Changes in purine metabolism and production of oxygen free radicals by intermittent partial umbilical cord occlusion in chronically instrumented fetal lambs.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain; Fetal Hypoxia; Hydrogen-Ion Concentration; Hypoxanthine; Inosine Monophosphate; Microdialysis; Oxidative Stress; Reactive Oxygen Species; Sheep; Superoxides; Time Factors; Umbilical Cord; Xanthine | 1998 |
Muscle anaerobic response to a maximal treadmill exercise test in Standardbred trotters.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Breeding; Energy Metabolism; Exercise Test; Female; Glycogen; Heart Rate; Horses; Hypoxanthine; Inosine Monophosphate; Lactates; Male; Muscle, Skeletal; Phosphocreatine; Physical Conditioning, Animal; Uric Acid; Xanthine | 1998 |
Plasma hypoxanthine and ammonia in humans during prolonged exercise.
Topics: Adenine Nucleotides; Adult; Ammonia; Exercise; Heart Rate; Humans; Hypoxanthine; Inosine Monophosphate; Kinetics; Lactic Acid; Male; Muscles; Oxygen Consumption; Physical Endurance; Uric Acid; Xanthine | 1999 |
Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Quaternary; Recombinant Proteins; Ribonucleotides; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Toxoplasma; Xanthine | 1999 |
Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
Topics: Amino Acid Sequence; Animals; Binding Sites; Borrelia burgdorferi Group; Catalytic Domain; Crystallography, X-Ray; Cysteine; Drug Design; Humans; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Motion; NAD; Pliability; Protein Conformation; Ribonucleotides; Sequence Alignment; Solvents; Static Electricity; Structure-Activity Relationship; Sulfates; Xanthine | 2000 |
A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.
Topics: Binding Sites; Catalysis; Hydrolysis; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; NAD; Ribonucleotides; Xanthine | 2002 |
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine | 2003 |
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
Topics: Amino Acid Sequence; Animals; Enzyme Inhibitors; Escherichia coli; Guanosine Monophosphate; Inosine Monophosphate; Leishmania donovani; Microbodies; Microscopy, Confocal; Mycophenolic Acid; NAD; Peroxisome-Targeting Signal 1 Receptor; Phylogeny; Protein Binding; Protozoan Proteins; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Subcellular Fractions; Substrate Specificity; Xanthine | 2007 |
A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cryptosporidium parvum; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NAD; Protein Binding; Ribonucleotides; Xanthine | 2008 |
Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Topics: Animals; Catalytic Domain; Deuterium Exchange Measurement; Guanosine Monophosphate; Humans; Hydrogen-Ion Concentration; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Plasmodium falciparum; Protein Binding; Purine Nucleotides; Ribonucleotides; Spectrum Analysis, Raman; Substrate Specificity; Toxoplasma; Xanthine | 2011 |
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Topics: Amino Acid Sequence; Apoenzymes; Bacillus anthracis; Benzimidazoles; Catalytic Domain; Enzyme Inhibitors; IMP Dehydrogenase; Inosine Monophosphate; Models, Molecular; Molecular Sequence Data; Mycophenolic Acid; NAD; Protein Binding; Ribonucleotides; Triazoles; Xanthine | 2012 |
Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors.
Topics: Animals; Biological Assay; Humans; IMP Dehydrogenase; Inosine Monophosphate; NAD; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Ribonucleotides; Xanthine | 2017 |
Crystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP.
Topics: Amino Acid Sequence; Guanosine Monophosphate; Inosine Monophosphate; Pentosyltransferases; Protein Conformation; Ribonucleotides; Substrate Specificity; Trypanosoma brucei brucei; Xanthine | 2019 |
Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic β Cells.
Topics: Animals; Biocatalysis; Cell Line, Tumor; Cells, Cultured; Cytoplasmic Granules; Fluorescent Antibody Technique; Humans; IMP Dehydrogenase; Inosine Monophosphate; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Multimerization; Ribonucleotides; Xanthine | 2021 |