xanthine has been researched along with hypoxanthine in 514 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 117 (22.76) | 18.7374 |
| 1990's | 185 (35.99) | 18.2507 |
| 2000's | 123 (23.93) | 29.6817 |
| 2010's | 66 (12.84) | 24.3611 |
| 2020's | 23 (4.47) | 2.80 |
| Authors | Studies |
|---|---|
| Dimmitt, MK; Miller, JP; Novinson, T; O'Brien, DE; Robins, RK; Simon, LN; Springer, RH | 1 |
| Bertuzzi, F; Poje, M; Poje, N; Rocić, B; Vucić-Lovrencić, M | 1 |
| Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T | 1 |
| Inoue, H; Ishikawa, H; Kamiya, H; Komatsu, Y; Miura, H; Murata, N; Murata, T; Sasaki, T; Shimizu, M; Suzuki, M | 1 |
| Grabb, MC; Roche, FM; Sciotti, VM; Van Wylen, DG | 1 |
| Cardelli, P; Ceci, F; Fiori, A; Peresempio, V; Salerno, C; Santulli, MC; Savi, MR; Strom, R | 1 |
| Hiroshige, K; Kunifuji, Y; Kuroiwa, A; Takasugi, M | 1 |
| Harada, A; Kitahara, S; Kobayashi, H; Kurokawa, T; Nakao, A; Nonami, T; Ozawa, T; Sugiyama, S; Takagi, H | 1 |
| Brunvand, H; Grong, K; Lekven, J; Westby, J | 1 |
| Coumans, WA; de Groot, MJ; van der Vusse, GJ | 1 |
| Kawachi, M; Kiyokawa, H; Kono, N; Kuwajima, M; Mineo, I; Nakajima, H; Shimizu, T; Tarui, S; Yorifuji, S | 1 |
| Alamillo, JM; Cárdenas, J; Pérez-Vicente, R; Pineda, M | 1 |
| Chen, XB; Chen, YK; Franklin, MF; Orskov, ER; Shand, WJ | 1 |
| Antolín, M; Cugat, E; de Lacy, AM; Fuster, J; García-Valdecasas, JC; González, FX; Grande, L; Rimola, A; Robusté, J; Visa, J | 1 |
| Hayashi, T; Hosoya, T; Sakai, O; Tabe, A | 1 |
| Fanburg, BL; Hassoun, PM; Landman, MJ; Lanzillo, JJ; Shedd, AL; Thappa, V | 1 |
| Babbs, CF; Salaris, SC; Voorhees, WD | 1 |
| Prodanov, E; Radi, R; Rubbo, H | 1 |
| Phillis, JW; Simpson, RE; Walter, GA | 1 |
| Ishii, T; Karasawa, Y; Kubota, T | 1 |
| Agren, H; Akerström, G; Hetta, J; Joborn, C; Ljunghall, S; Niklasson, F; Rastad, J; Wide, L | 1 |
| Bannai, S; Ishii, T; Miura, K; Sugita, Y | 1 |
| Benoit, R; O'Brien, WF; Porter, KB | 1 |
| Dueland, AN; Dueland, S; Myhre, K; Saugstad, OD | 1 |
| Camiña, F; Castro-Gago, M; Lojo, S; Rodríguez-Núñez, A; Rodríguez-Segade, S | 2 |
| Hassinen, IE; Pekka Raatikainen, MJ; Peuhkurinen, KJ | 1 |
| Hasegawa, J; Hisatome, I; Ishiko, R; Kobayashi, M; Kotake, H; Mashiba, H; Ogino, K; Sasaki, N; Shigemasa, C; Yoshida, A | 1 |
| Himmel, HM; Ravens, U; Sadony, V | 1 |
| Molinelli, M; Pagani, R; Porcelli, B; Tabucchi, A; Valerio, P; Vannoni, D | 1 |
| González, AG; Jiménez, ML; Mateos, FA; Puig, JG; Ramos, TH; Romera, NM | 1 |
| Nishino, T; Sato, S; Tatsumi, K | 1 |
| López Jiménez, M; Luz Picazo, M; Mateos, FA; Miranda Carús, ME; Ortíz Vázquez, J; Puig, JG | 1 |
| Kawachi, M; Kiyokawa, H; Kono, N; Kuwajima, M; Mineo, I; Nakajima, H; Nishimura, T; Ono, A; Shimizu, T; Yorifuji, S | 1 |
| Poulsen, JP; Saugstad, OD | 1 |
| de Jong, JW; Janssen, M; Keijzer, E; Nieukoop, AS | 1 |
| Agbedana, OE; Hada, T; Higashino, K; Imanishi, H; Moriwaki, Y; Nanahoshi, M; Suda, M; Takahashi, S; Yamamoto, T | 1 |
| Hosoya, T; Ichida, K; Sakai, O; Tabe, A | 1 |
| Bagger, JP; Henningsen, P; Nielsen, TT; Pedersen, AK; Thomassen, A | 1 |
| Itoh, Y; Kitazawa, Y; Matsubara, M; Suzuki, K; Takeyama, N; Tanaka, T | 1 |
| Farstad, M; Karwinski, W; Søreide, O; Ulvik, R | 1 |
| Kobayashi, H; Kurokawa, T; Nonami, T; Ozawa, T; Sugiyama, S; Takagi, H | 1 |
| Banaszak, F; Głuszek, J; Tykarski, A | 2 |
| Doctor, RB; Mandel, LJ | 1 |
| Greenwood, R; Harkness, RA; McCreanor, GM | 1 |
| Dohi, K; Kawasaki, T; Marubayashi, S; Yamada, K | 1 |
| Elsayed, NM; Ferraris, SP; Lew, H | 1 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T | 1 |
| Opsomer, C; Stanssens, P; Steyaert, J; Wyns, L | 1 |
| Dusbábek, F; Jegorov, A; Simek, P; Tríska, J | 1 |
| Gudbjörnsson, B; Hällgren, R; Niklasson, F; Zak, A | 1 |
| Cheung, KS; Hedstrom, L; Wang, CC | 1 |
| Cassens, RG; Faustman, C | 1 |
| Dan, T; Koga, H | 1 |
| Ekelund, S; Kjaergaard, N; Kristiansen, FV; Møller-Petersen, JF; Petersen, PL; Skovbo, P | 1 |
| Bergsland, J; Feldman, MJ; Lajos, PS; Lobalsamo, L; Vanwylen, DG | 1 |
| Prodanov, E; Radi, R; Rubbo, H; Thomson, L | 1 |
| Bilenko, MV; Nagler, LG; Oktiabr'skaia, LA; Rashba, IuE; Vartanian, LS | 1 |
| Harada, A; Kuroe, K; Kurokawa, T; Nakao, A; Nonami, T; Satake, M; Takagi, H | 1 |
| Gardiner, EE; Keng, JY; Newberry, RC | 1 |
| Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA | 1 |
| Oyasaeter, S; Poulsen, JP; Rognum, TO; Sanderud, J; Saugstad, OD | 1 |
| Oyasaeter, S; Poulsen, JP; Rognum, TO; Saugstad, OD | 1 |
| Grum, CM; Ketai, LH; Supinski, GS | 1 |
| Eklof, B; Jabs, CM; Neglen, P; Thomas, EJ | 1 |
| Chen, XB; Hovell, FD; Orskov, ER | 1 |
| Brown, DS; Chen, XB; Hovell, FD; Orskov, ER | 1 |
| Dorheim, TA; Mentzer, RM; Van Wylen, DG; Wang, T | 1 |
| Beretta, M; Motterlini, R; Rovida, E; Samaja, M; Tarantola, M | 1 |
| Drange, A; Farstad, M; Karwinski, W; Søreide, O; Ulvik, R | 1 |
| Bos, E; de Jong, JW; Huizer, T; Nieukoop, AS; Stroeve, RJ; van der Meer, P | 1 |
| Achterberg, PW; de Jong, JW; Huizer, T | 1 |
| Brown, JK; Harkness, RA; Laing, I | 1 |
| Prodanov, E; Radi, RA; Rubbo, H | 1 |
| Lemasters, JJ; Thurman, RG; Zhong, Z | 1 |
| Hüttermann, J; Sieber, K | 1 |
| Czarnecki, W; de Jong, JW; Herbaczyńska-Cedro, K; Huizer, T; Ruzyllo, W | 1 |
| Castro-Gago, M; Guitián, JP; Rocamonde, SL; Rodriguez, IN; Rodriguez-Núñez, A; Rodriguez-Segade, S | 1 |
| Barnard, HC; Barnard, SP; Maartens, JJ; Potgieter, GM; van Jaarsveld, H | 1 |
| Gresser, U; Zöllner, N | 1 |
| Di Stefano, A; Leoncini, R; Marinello, E; Pizzichini, M; Porcelli, B; Taddeo, A | 2 |
| Khramtsova, SN; Pimenov, AM; Potapova, GI; Shapot, VS; Tikhonov, IuV; Toguzov, RT | 1 |
| Lemasters, JJ; Marzi, I; Thurman, RG; Zhi, ZN; Zimmermann, FA | 1 |
| Parker, BR; Stevens, SK | 1 |
| Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P | 1 |
| Sudo, J; Suzuki, Y | 2 |
| García Puig, J; López Jiménez, M; Mateos Antón, F; Ortiz Vázquez, J; Pascual Castroviejo, I; Ramos Hernández, T | 1 |
| Isaacs, M; Muindi, J; Stevens, YW; Warrell, RP; Young, CW | 1 |
| Mĕchurová, A; Novák, L; Stípek, S; Trojan, S | 1 |
| Demin, VF; Pimenov, AM; Toguzov, RT | 1 |
| Mela-Riker, L; Vlessis, AA | 1 |
| Brown, JK; Harkness, RA; Livingston, JH; McCreanor, GM; O'Hare, AE | 1 |
| Brown, JK; Harkness, RA; Livingston, JH; McCreanor, GM | 1 |
| Kanemitsu, H; Nihei, H; Oka, H; Sano, K; Tamura, A | 1 |
| Clement, R; Das, DK; Engelman, RM; Otani, H; Prasad, MR; Rao, PS | 1 |
| Fox, IH; Tekkanat, KK | 1 |
| Andersson, P; Butcher, S; Hagberg, H; Hamberger, A; Lehmann, A; Sandberg, M | 1 |
| D'Alecy, LG; Frank, RS; Moursi, MM; Podrazik, RM; Zelenock, GB | 1 |
| Andiné, P; Hagberg, H; Kjellmer, I; Thiringer, K | 1 |
| Novák, L; Stastný, F; Stípek, S; Trojan, S; Vinklár, P | 1 |
| Fox, IH; Hornykiewicz, O; Kapur, BM; Kish, SJ; Lloyd, K | 1 |
| Andersen, PT; Bacher, T; Stentoft, J | 1 |
| Jiménez, ML; Mateos, FA; Puig, JG; Ramos, TH | 1 |
| Nihei, H | 1 |
| Abd-Elfattah, AS; Brunsting, LA; Doherty, NE; Jessen, ME; Lekven, J; Wechsler, AS | 1 |
| Escribano, J; Garcia-Canovas, F; Garcia-Carmona, F | 1 |
| Johnson, JL; Mandell, R; Shih, VE; Wuebbens, MM | 1 |
| Degrell, I; Hetta, J; Niklasson, F | 1 |
| O'Regan, MH; Phillis, JW; Walter, GA | 1 |
| Coumans, WA; Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M | 1 |
| Kootstra, G; Maessen, JG; van der Vusse, GJ; Vork, M | 1 |
| Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Yamamoto, T | 2 |
| Gavin, JB; Humphrey, SM; Vanderwee, MA | 1 |
| Akaoka, I; Fujimori, S; Itoh, H; Kanbayashi, T; Kaneko, K; Miyashita, H; Nakayama, Y; Oyama, H | 1 |
| Weinberg, JM | 1 |
| Ghia, JN; Hunt, RD; Kafer, ER; Mueller, RA; Powers, SK; Rosner, MJ | 1 |
| Degrell, I; Niklasson, F | 1 |
| Andreoli, SP; Bergstein, JM; Clark, JH; McGuire, WA | 1 |
| Granger, DN; Parks, DA | 1 |
| Andersson, P; Butcher, S; Hagberg, H; Jacobson, I; Lacarewicz, J; Sandberg, M | 1 |
| Caldarone, R; Leoncini, R; Lorenzi, M; Marinello, E; Vannoni, D | 1 |
| Kather, H; Waas, W; Wieland, E | 1 |
| Kamatani, N; Kitamura, M; Kojima, T; Nishina, T; Nishioka, K | 2 |
| Hadano, S; Ito, A; Ogasawara, M | 1 |
| Cross, M; Emmerson, BT; Gordon, RB; Thomson, DB | 1 |
| Aliberti, LM; Severini, G | 1 |
| Al-Bander, HA; Booth, BE; Kabra, PM; Kurtz, TW; Morris, RC; Portale, AA; Serena, BG; Tsai, HC | 1 |
| Franzus, MJ; Malcolm, GB; Pine, L | 1 |
| Dörner, K; Krämer, M; Manzke, H | 1 |
| Fox, IH; Woolliscroft, JO | 1 |
| Armiger, LC; Hollis, DG; Seelye, RN | 1 |
| DeMoll, E; Tsai, L | 1 |
| Castro-Gago, M; Del Rio, R; Lojo, S; Novo, I; Rodriguez, A; Rodriguez-Segade, S | 1 |
| Pimenov, AM; Prokudin, VIu; Sitnikov, VF; Tikhonov, IuV; Toguzov, RT | 1 |
| Fox, IH; Jiménez, ML; Mateos, FA; Puig, JG | 1 |
| Knudsen, F; Thorgaard Andersen, P | 1 |
| Betz, AL | 1 |
| Emmerson, BT; Gordon, RB; Keough, D; Kranen, S | 1 |
| Balla, G; Karmazsin, L | 1 |
| Callerud, T; Friman, G; Niklasson, F; Ronquist, G | 1 |
| Farley, BA; Ohlsson-Wilhelm, BM; Rowley, PT; Rudolph, NS | 1 |
| Fredholm, BB; Hohlbach, G; Schoenberg, MH | 1 |
| Sollevi, A; von Holst, H | 1 |
| Dantzker, DR; Fox, IH; Grum, CM; Simon, RH | 1 |
| Daiguji, Y; Hasumura, Y; Izumi, N; Sakai, H; Shinohara, S; Takeuchi, J | 1 |
| Buka, MR; Zhagat, RA; Zvirgzda, IK | 1 |
| Agren, H; Hällgren, R; Niklasson, F | 1 |
| Agren, H; Franzén, O; Niklasson, F; Osterberg, B | 1 |
| Achterberg, PW; de Jong, JW; de Tombe, PP; Harmsen, E | 1 |
| Al-Safi, SA; Maddocks, JL | 1 |
| Dockrell, HM; Playfair, JH; Targett, GA; Taverne, J; Wozencraft, AO | 1 |
| Buckley, BM; Fisher, RA; Simmonds, HA; Spencer, RE; Stutchbury, JH; Webster, DR; Wooder, M | 1 |
| Fox, IH; Puig, JG | 1 |
| Baltassat, P; Bory, C; Boulieu, R; Divry, P | 1 |
| Bargnoux, H; Berger, JA; Bussière, JL; Chabard, JL; Lartigue-Mattéi, C; Petit, J; Rampon, S; Ristori, JM | 1 |
| Parsons, DS; Shaw, MI | 1 |
| Ajello, L; Honbo, S; Padhye, AA | 1 |
| Geirsson, RT; Harkness, RA; McFadyen, IR | 1 |
| Fredholm, B; Hohlbach, G; Schildberg, FW; Schoenberg, M | 1 |
| Hirose, S; Kito, M; Takeshima, S; Tawa, R | 1 |
| Hropot, M; von Kerékjártó, B | 1 |
| Ferradini, C; Pasquier, C; Pucheault, J; Santamaria, J | 1 |
| Coade, SB; Harkness, RA; Simmonds, RJ | 1 |
| de Jong, JW; de Tombe, PP; Harmsen, E; Keijzer, E | 1 |
| De Jong, JW; De Tombe, PP; Harmsen, E | 1 |
| Baltassat, P; Bory, C; Boulieu, R; Gonnet, C | 2 |
| Bakken, AM; Farstad, M; Grong, K; Lekven, J; Stangeland, L | 1 |
| Brown, JK; Harkness, RA; Levin, SD | 1 |
| Mertz, DP | 1 |
| Slowiaczek, P; Tattersall, MH | 1 |
| Jezewska, MM; Kamiński, ZW | 1 |
| Clifford, AJ; Savaiano, DA | 1 |
| Aruoma, OI; Chimel, K; Cross, CE; Halliwell, B; Jenner, A; Spencer, JP; Wu, R | 1 |
| D'Armini, AM; Egan, TM; Henke, DC; Lemasters, JJ; Roberts, CS; Tom, EJ | 1 |
| Higashino, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T | 2 |
| Furuchi, K; Haji, S; Iso, A; Kasahara, H; Kitani, G; Sakata, K; Sou, E; Sun, K; Usami, M; Zheng, JH | 1 |
| Bory, C; Boulieu, R; Chantin, C | 3 |
| Barshop, B; Nyhan, WL; Page, T; Yu, AL | 1 |
| Farnetani, MA; Marinello, E; Pagani, R; Pizzichini, M; Porcelli, B; Roscioni, G | 1 |
| Leoncini, R; Marinello, E; Pagani, R; Pizzichini, M; Porcelli, B; Vannoni, D | 1 |
| de Miguel, E; Gil, A; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ | 1 |
| Agbedana, OE; Higashino, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Yamamoto, T; Yokoyama, Y | 1 |
| Li, T; Liu, Z; Wang, E | 1 |
| Almaas, R; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H; Sundar, T | 1 |
| Angel, MF; Chung, HK; Im, MJ; Manson, PN; Vander Kolk, CA | 1 |
| Eklund, T; Hillered, L; Wahlberg, J | 1 |
| Delvoux, B; Greiling, H; Kock, R; Sigmund, M | 1 |
| Inoue, I; Maeda, K; Miwa, M; Morita, H; Nakai, S; Odani, H; Shinzato, T | 1 |
| de Miguel, E; Gil, AA; Mateos, FA; Miranda, ME; Pérez de Ayala, C; Puig, JG; Torres, RJ | 1 |
| Hammon, JW; Hudspeth, DA; McGee, DS; Nakanishi, K; Sato, H; Van Wylen, DG; Vinten-Johansen, J; Williams, MW; Zhao, ZQ | 1 |
| Dusbábek, F; Jegorov, A; Simek, P | 1 |
| Borotz, SE; Pfefferkorn, ER | 1 |
| Gidday, JM; Gonzales, ER; Kim, YB; Park, TS; Shah, AR | 1 |
| Hiroshige, K; Kuroiwa, A; Takasugi, M; Yuu, K | 1 |
| Guilbault, GG; Haemmerli, SD; Hlavay, J | 1 |
| Ishiguro, N; Miura, T; Shimizu, T; Tamura, Y; Wakabayashi, T; Yabe, Y | 1 |
| Oyasaeter, S; Rognum, TO; Rootwelt, T; Saugstad, OD; Stoltenberg, L | 1 |
| Ericson, A; Ronquist, G; Ulmsten, U; Waldenström, A; Wedenberg, K | 1 |
| Kawachi, M; Kono, N; Kuwajima, M; Matsuzawa, Y; Mineo, I; Nakajima, H; Nishimura, T; Ono, A; Shimizu, T | 1 |
| Downey, HF; Van Wylen, DG; Williams, AG | 1 |
| Oyasaeter, S; Rootwelt, T; Saugstad, OD | 1 |
| Bollar, A; Camiña, F; Castro-Gago, M; Rodríguez-Núñez, A; Rodríguez-Segade, S | 1 |
| de Haan, HH; de Haan, J; Hasaart, TH; Van Reempts, JL; Vles, JS | 1 |
| Ronquist, G; Steingrímsdóttir, T; Ulmsten, U | 1 |
| Ekblom, B; Hellsten-Westing, Y; Kaijser, L; Sjödin, B | 1 |
| Higashino, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Yamamoto, T | 2 |
| Oyasaeter, S; Poulsen, JP; Saugstad, OD | 1 |
| Bromberg, Y; Brosh, S; Sidi, Y; Sperling, O; Zoref-Shani, E | 1 |
| Delvoux, B; Greiling, H; Kock, R | 1 |
| Adachi, K; Inoue, T; Mu, Z; Okochi, T; Sumikawa, K | 1 |
| Bissbort, SH; Oosthuizen, HM; Ungerer, JP | 1 |
| Bollinger, RR; Canada, AT; Coleman, LR; Fabian, MA | 1 |
| Dagianti, A; Di Pierro, D; Fedele, F; Giardina, B; Lazzarino, G; Penco, M; Romano, S; Tavazzi, B | 1 |
| de Jong, JW; Janssen, M; Koster, JF; Tavenier, M | 1 |
| Carlucci, F; De Martino, A; Lorenzi, M; Marinello, E; Pagani, R; Pizzichini, M; Porcelli, B; Tabucchi, A | 1 |
| Hauge, S; Oyasaeter, S; Poulsen, JP; Rognum, TO; Saugstad, OD | 1 |
| Grauel, EL; Grune, T; Schmidt, H; Siems, WG | 1 |
| Lampinen, KJ; Pösö, AR; Räsänen, LA | 1 |
| Andersen, P; Haljamäe, H; Hindberg, I; Ibsen, A; Naesh, O; Skielboe, M; Sztuk, F | 1 |
| Argomaniz, L; Llorente, P; López-Sendón, JL; Martín-Jadraque, L; Martín-Jadraque, R; Montero, C; Mostaza, JM | 1 |
| Kalnovicová, T; Kuracka, L; Líska, B; Turcáni, P | 1 |
| Gross, GJ; Mei, DA; Nithipatikom, K | 1 |
| Augustin, AJ; Böker, T; Breipohl, W; Hunt, S; Spitznas, M | 1 |
| Bada, V; Gvozdjáková, A; Herichová, I; Kucharská, J; Snircová, M | 1 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Carson, SM; Christakis, GT; Cohen, G; Grewal, R; Ivanov, J; Mickle, DA; Rao, V; Weisel, RD | 1 |
| Bökkerink, JP; DeAbreu, RA; Keuzenkamp-Jansen, CW; Lambooy, MA; Trijbels, JM | 1 |
| Bellini, C; Bertola, A; Bonioli, E; Caruso, U; DiStefano, A; Dorche, C; Fantasia, AR; Minniti, G; Palmieri, A | 1 |
| Arduini, A; Ciancaglini, M; Del Galio, P; Gallenga, PE; Giacomello, A; Gizzi, F; Mastropasqua, L; Spoto, G | 1 |
| Carswell, HV; Graham, DI; Stone, TW | 1 |
| Evans, TW; Gutteridge, JM; Lamb, NJ; Quinlan, GJ; Tilley, R | 1 |
| Heikkilä, L; Kinnula, VL; Mattila, S; Raivio, KO; Sarnesto, A; Toivonen, H | 1 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 2 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Ohata, H; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Barclay, KD; Buckley, SJ; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK | 1 |
| Cascante, M; Curto, R; Sorribas, A; Voit, EO | 1 |
| Forrest, CR; He, W; Hopper, R; Neligan, P; Pang, CY; Xu, H; Zhong, A | 1 |
| Hirakoba, K; Sahlin, K; Söderlund, K; Tonkonogi, M | 1 |
| Aarts, LP; Gerritsen, WB; Haas, FJ; Morshuis, WJ | 1 |
| Foga, IO; Geiger, JD; Hasinoff, BB; Nath, A | 1 |
| Bargossi, AM; Bianchi, GP; Grossi, G | 1 |
| Nickel, RF; Reijngoud, DJ; van Dijk, TH; van Zuilen, CD | 1 |
| Colditz, PB; Dunster, KR; Earl, JW; East, CE; Nath, CE | 1 |
| Li, B; Moshfeghi, AA; Osinski, J; Park, SS; Rosenbaum, PS; Roth, S; Toledano, AY | 1 |
| Fairbanks, L; Hughes, EF; Robinson, RO; Simmonds, HA | 1 |
| Kempski, OS; Lowitzsch, K; Stover, JF | 1 |
| Boda, D; Karg, E; Mészáros, T; Németh, I; Pintér, S; Virág, G | 1 |
| Konvaĭ, VD; Zolin, PP | 1 |
| Barrier, L; Chalon, S; Guerraoui, A; Guilloteau, D; Huguet, F; Tallineau, C | 1 |
| Delivoria-Papadopoulos, M; Marro, P; Pastuszko, P; Wilson, DF | 1 |
| Czauderna, M; Kowalczyk, J | 2 |
| Kakino, J; Naito, Y; Sato, R | 1 |
| Andersson, S; Höckerstedt, K; Lapatto, R; Linder, N; Mäkisalo, H; Pesonen, EJ; Raivio, KO; Sarnesto, A | 1 |
| Hayakawa, Y; Masaoka, N; Ohgame, S; Sakata, H; Satoh, K; Takahashi, H | 1 |
| Markusheva, LI; Tikhonov, IuV; Toguzov, RT | 1 |
| Jayakumar, J; Seymour, AM; Smolenski, RT; Yacoub, MH | 1 |
| Makarewicz, W; Smolenski, RT; Yacoub, MH; Zych, M | 1 |
| Di Ilio, C; Gizzi, F; Odorisio, M; Palka, GD; Papponetti, M; Ruffini, I; Spoto, G | 1 |
| Arezzini, L; Billarelli, C; Carlucci, F; Pizzichini, M; Terzuoli, L | 1 |
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| Bonifacio, A; De Leo, L; Di Silvestre, A; Esposito, A; Florian, F; Fornasaro, S; Lagatolla, C; Mezzarobba, M; Not, T; Pallavicini, A; Sergo, V | 1 |
| Allegaert, K; Chu, WY; Dorlo, TPC; Huitema, ADR | 1 |
| Anitta, S; Meenakshi, S; Sekar, C; Sudhan, N | 1 |
| Abramov, G; Pozdnyakova, Y; Shakeev, K; Shestakov, D; Tankibaeva, N; Tusupbekova, M | 1 |
| Deng, D; Luo, L; Wang, D; Wang, T; Zhang, C; Zhang, L | 1 |
| Anand, SK; Kumar, KG; Mathew, MR | 1 |
| Han, X; Jiang, M; Li, Y; Liao, Z; Liu, X; Tong, J; Wang, Y; Zhao, H | 1 |
9 review(s) available for xanthine and hypoxanthine
| Article | Year |
|---|---|
Xanthine oxidase: biochemistry, distribution and physiology.
Topics: Animals; Histocytochemistry; Humans; Hypoxanthine; Hypoxanthines; Iron; Isoenzymes; Oxidation-Reduction; Species Specificity; Tissue Distribution; Xanthine; Xanthine Oxidase; Xanthines | 1986 |
[Methods of determining adenosine deaminase (review of the literature)].
Topics: Adenosine Deaminase; Ammonia; Catalysis; Chromatography, Ion Exchange; Chromatography, Liquid; Chromatography, Thin Layer; Erythrocytes; Hypoxanthine; Hypoxanthines; Inosine; Lymphocytes; Methods; Nucleoside Deaminases; Radioimmunoassay; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Uric Acid; Xanthine; Xanthines | 1982 |
[Oxypurine].
Topics: Humans; Hypoxanthine; Xanthine | 1999 |
[Molecular mechanism for urinary excretion of hypoxanthine and xanthine].
Topics: Animals; Benzbromarone; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kidney; Membrane Transport Proteins; Probenecid; Pyrazinamide; Uricosuric Agents; Xanthine | 2003 |
[Purine metabolism in patients with renal failure].
Topics: Allopurinol; Antimetabolites; Glomerulonephritis; Humans; Hyperuricemia; Hypoxanthine; Kidney; Kidney Failure, Chronic; Purines; Renal Dialysis; Uric Acid; Xanthine | 2004 |
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).
Topics: Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Humans; Hyperuricemia; Hypoxanthine; Lactic Acid; NAD; Oxidation-Reduction; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2005 |
[The biochemical markers of hypoxic perinatal affections of central nervous system in newborns].
Topics: Activins; Biomarkers; Central Nervous System; Female; Fetal Hypoxia; Humans; Hypoxanthine; Infant, Newborn; Nerve Growth Factors; Phosphopyruvate Hydratase; Pregnancy; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Xanthine | 2012 |
Recent progress in nanomaterial-based electrochemical and optical sensors for hypoxanthine and xanthine. A review.
Topics: Colorimetry; Electrochemical Techniques; Fluorescent Dyes; Food Analysis; Food Preservation; Graphite; Hypoxanthine; Metal Nanoparticles; Metal-Organic Frameworks; Nanotubes, Carbon; Photometry; Polymers; Xanthine | 2019 |
Analysis of Metabolites in Gout: A Systematic Review and Meta-Analysis.
Topics: Creatinine; Gout; Humans; Hypoxanthine; Uric Acid; Xanthine | 2023 |
20 trial(s) available for xanthine and hypoxanthine
| Article | Year |
|---|---|
Clinical and biochemical assessments of damage due to perinatal asphyxia: a double blind trial of a quantitative method.
Topics: Asphyxia Neonatorum; Child Development; Clinical Trials as Topic; Creatinine; Developmental Disabilities; Double-Blind Method; Growth Disorders; Humans; Hypoxanthine; Hypoxanthines; Hypoxia, Brain; Infant; Infant, Newborn; Kidney Diseases; Methods; Xanthine; Xanthines | 1988 |
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol | 1995 |
Free oxypurines in plasma and urine of gout patients before and after a purine-free diet.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Creatinine; Diet Therapy; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Purines; Reference Values; Uric Acid; Xanthine; Xanthines | 1994 |
Role of adenosine in dialysis-induced hypotension.
Topics: Adenosine; Aged; Caffeine; Female; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Models, Biological; Norepinephrine; Renal Dialysis; Sympathetic Nervous System; Vascular Resistance; Vasodilation; Xanthine; Xanthines | 1994 |
Metabolism of intravenously administered high-dose 6-mercaptopurine with and without allopurinol treatment in patients with non-Hodgkin lymphoma.
Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Humans; Hypoxanthine; Hypoxanthines; Individuality; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methylthioinosine; Nucleotides; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Plasma hypoxanthine levels in ARDS: implications for oxidative stress, morbidity, and mortality.
Topics: Adolescent; Adult; Aged; APACHE; Bronchoalveolar Lavage Fluid; Child; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Male; Middle Aged; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Respiratory Distress Syndrome; Survival Analysis; Xanthine; Xanthines | 1997 |
Allopurinol does not increase free radical scavenging capacity during reperfusion in coronary artery bypass graft patients.
Topics: Aged; Allopurinol; Analysis of Variance; Coronary Artery Bypass; Coronary Disease; Double-Blind Method; Free Radical Scavengers; Free Radicals; Humans; Hypoxanthine; Infusions, Intravenous; Intraoperative Period; Male; Middle Aged; Preoperative Care; Probability; Reference Values; Reperfusion; Sensitivity and Specificity; Uric Acid; Xanthine | 2000 |
Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol.
Topics: Adult; Allopurinol; Cholesterol; Creatinine; Drug Interactions; Fenofibrate; Gout Suppressants; Humans; Hypolipidemic Agents; Hypoxanthine; Male; Oxypurinol; Purines; Triglycerides; Uric Acid; Xanthine | 2001 |
Effects of angiotensin II infusion on renal excretion of purine bases and oxypurinol.
Topics: Administration, Oral; Adult; Allopurinol; Angiotensin II; Blood Pressure; Creatinine; Humans; Hypoxanthine; Infusions, Intravenous; Kidney; Male; Middle Aged; Oxypurinol; Purines; Reference Values; Sodium; Uric Acid; Xanthine | 2002 |
Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases.
Topics: Adult; Ammonia; Beer; Central Nervous System Depressants; Creatinine; Ethanol; Exercise; Exercise Test; Humans; Hypoxanthine; Lactic Acid; Male; Purines; Pyruvic Acid; Uric Acid; Xanthine | 2003 |
Home-based exercise training modulates pro-oxidant substrates in patients with chronic heart failure.
Topics: Adult; Arginine; Cross-Over Studies; Exercise; Female; Heart Failure; Humans; Hypoxanthine; Male; Middle Aged; Nitrates; Nitrites; Xanthine | 2005 |
Oxygent as a top load to colloid and hyperoxia is more effective in resuscitation from hemorrhagic shock than colloid and hyperoxia alone.
Topics: Animals; Body Weight; Colloids; Contrast Media; Dogs; Fluorocarbons; Hematocrit; Hemodynamics; Hemorrhage; Hydrocarbons, Brominated; Hydroxyethyl Starch Derivatives; Hypoxanthine; Hypoxia; Intestinal Mucosa; Oxygen; Oxygen Consumption; Perfusion; Shock, Hemorrhagic; Spleen; Time Factors; Xanthine | 2005 |
Study of free radicals in neonates born through meconium stained amniotic fluid deliveries.
Topics: Amniotic Fluid; Asphyxia Neonatorum; Female; Free Radicals; Humans; Hypoxanthine; Hypoxia-Ischemia, Brain; Infant, Newborn; Labor, Obstetric; Malondialdehyde; Meconium; Pregnancy; Xanthine | 2005 |
Effects of a fenofibrate/losartan combination on the plasma concentration and urinary excretion of purine bases.
Topics: Adult; Antihypertensive Agents; Cholesterol; Dose-Response Relationship, Drug; Fenofibrate; Humans; Hypolipidemic Agents; Hypoxanthine; Losartan; Male; Metabolic Clearance Rate; Middle Aged; Time Factors; Triglycerides; Uric Acid; Xanthine | 2006 |
Pharmacokinetics, pharmacodynamics and safety of febuxostat, a non-purine selective inhibitor of xanthine oxidase, in a dose escalation study in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Models, Biological; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase | 2006 |
Plasmatic markers of muscular stress in isokinetic exercise.
Topics: Adult; Biomarkers; Creatine Kinase; Creatine Kinase, MB Form; Exercise; Exercise Test; Humans; Hypoxanthine; Leukocyte Count; Lymphocyte Count; Male; Muscle Fatigue; Muscle, Skeletal; Myoglobin; Neutrophils; Troponin I; Uric Acid; Xanthine | 2007 |
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Biotransformation; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Protein Binding; Sex Factors; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase; Young Adult | 2008 |
Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial.
Topics: Adult; Animals; Cross-Over Studies; Gout; Humans; Hypoxanthine; Male; Middle Aged; Milk; Purine Nucleosides; Seasons; Soy Milk; Urea; Uric Acid; Xanthine; Young Adult | 2010 |
Evaluation and characterization of the effects of ticagrelor on serum and urinary uric acid in healthy volunteers.
Topics: Adenosine; Adult; Cross-Over Studies; Humans; Hyperuricemia; Hypoxanthine; Male; Middle Aged; Purinergic P2Y Receptor Antagonists; Ticagrelor; Time Factors; Uric Acid; Xanthine | 2012 |
Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.
Topics: Allopurinol; Biomarkers; Enzyme Inhibitors; Humans; Hypoxanthine; Hypoxia-Ischemia, Brain; Infant, Newborn; Oxypurinol; Uric Acid; Xanthine; Xanthine Oxidase | 2022 |
485 other study(ies) available for xanthine and hypoxanthine
| Article | Year |
|---|---|
Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo(1,5-alpha)pyrimidines.
Topics: Animals; Cattle; Hydrogen-Ion Concentration; Kinetics; Milk; Pyrazoles; Pyrimidines; Spectrophotometry, Ultraviolet; Xanthine Oxidase | 1976 |
Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells.
Topics: Animals; Arginine; Glucose; Hyperuricemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Protein Binding; Rats; Structure-Activity Relationship; Uric Acid | 2005 |
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship | 2006 |
Mutations induced by DNA lesions in hot spots of the c-Ha-ras gene.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Line, Transformed; DNA; DNA Damage; Genes, ras; Guanine; Hypoxanthine; Hypoxanthines; Mice; Molecular Sequence Data; Mutation; Xanthine; Xanthines | 1992 |
Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Male; Neurotoxins; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Xanthine; Xanthines | 1992 |
Effect of inorganic phosphate on hypoxanthine transport in isolated brain microvessels.
Topics: Alkaline Phosphatase; Animals; Blood Vessels; Blood-Brain Barrier; Brain; Cattle; gamma-Glutamyltransferase; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; In Vitro Techniques; Phosphates; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1992 |
[Studies on purine-pyrimidine metabolism (1)--Quantitation of purine-pyrimidine metabolites and allopurinol-oxipurinol in biological fluids].
Topics: Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Oxypurinol; Purines; Pyrimidines; Uric Acid; Xanthine; Xanthines | 1992 |
The effects of gamma-glutamylcysteine ethyl ester, a prodrug of glutathione, on ischemia-reperfusion-induced liver injury in rats.
Topics: Adenine Nucleotides; Animals; Dipeptides; Glutathione; Glutathione Disulfide; Hypoxanthine; Hypoxanthines; Liver; Male; Prodrugs; Rats; Rats, Wistar; Reperfusion Injury; Xanthine; Xanthines | 1992 |
Myocardial adenine nucleotide depletion within 1 h of acute coronary artery occlusion.
Topics: Adenine Nucleotides; Animals; Cats; Constriction; Coronary Vessels; Energy Metabolism; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Myocardial Ischemia; Myocardium; Xanthine; Xanthines | 1992 |
The nucleotide metabolism in lactate perfused hearts under ischaemic and reperfused conditions.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Guanosine Triphosphate; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphocreatine; Pyruvates; Rats; Rats, Inbred Lew; Time Factors; Xanthine; Xanthines | 1992 |
Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.
Topics: Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Parkinson Disease; Probenecid; Pyrazinamide; Uric Acid; Xanthine; Xanthines | 1992 |
Purification and substrate inactivation of xanthine dehydrogenase from Chlamydomonas reinhardtii.
Topics: Acetaldehyde; Adenine; Animals; Chlamydomonas reinhardtii; Enzyme Activation; Hypoxanthine; Hypoxanthines; NAD; NADP; Spectrophotometry; Xanthine; Xanthine Dehydrogenase; Xanthines | 1992 |
The effect of feed intake and body weight on purine derivative excretion and microbial protein supply in sheep.
Topics: Allantoin; Animals; Bacterial Proteins; Body Weight; Digestion; Eating; Female; Hypoxanthine; Hypoxanthines; Male; Purines; Rumen; Sheep; Uric Acid; Xanthine; Xanthines | 1992 |
Adenine nucleotides in liver tissue and organ viability in human liver transplantation.
Topics: Adenine Nucleotides; Alanine Transaminase; Bile; Biopsy; Female; Humans; Hypoxanthine; Hypoxanthines; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Reperfusion; Xanthine; Xanthines | 1992 |
[Metabolic disorder of purine nucleotide in patients with chronic renal failure].
Topics: Allopurinol; Humans; Hypoxanthine; Hypoxanthines; Kidney Failure, Chronic; Purine Nucleotides; Renal Dialysis; Uremia; Uric Acid; Xanthine; Xanthines | 1992 |
Inhibition of pulmonary artery smooth muscle cell growth by hypoxanthine, xanthine, and uric acid.
Topics: Animals; Cattle; Cell Hypoxia; Chromatography, High Pressure Liquid; Culture Media; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Muscle Development; Muscle, Smooth, Vascular; Pulmonary Artery; Uric Acid; Xanthine; Xanthines | 1992 |
Methylene blue as an inhibitor of superoxide generation by xanthine oxidase. A potential new drug for the attenuation of ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney; Lipid Peroxidation; Liver; Methylene Blue; Models, Biological; Oxidation-Reduction; Rats; Reperfusion Injury; Succimer; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Substrate inhibition of xanthine oxidase and its influence on superoxide radical production.
Topics: Animals; Cattle; Electron Transport; Free Radicals; Horses; Hypoxanthine; Hypoxanthines; Kinetics; Substrate Specificity; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: effects of the adenosine deaminase inhibitor deoxycoformycin.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Amino Acids; Animals; Blood Pressure; Carbon Dioxide; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Ischemic Attack, Transient; Male; Neurotransmitter Agents; Oxygen; Pentostatin; Rats; Rats, Inbred Strains; Xanthine; Xanthines | 1991 |
Absorption and metabolism of purines by the lower intestine of the chicken.
Topics: Adenine; Animals; Chickens; Guanine; Hypoxanthine; Hypoxanthines; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Purines; Uric Acid; Xanthine; Xanthines | 1991 |
Cerebrospinal fluid calcium, parathyroid hormone, and monoamine and purine metabolites and the blood-brain barrier function in primary hyperparathyroidism.
Topics: Blood-Brain Barrier; Calcium; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hyperparathyroidism; Hypoxanthine; Hypoxanthines; Methoxyhydroxyphenylglycol; Neurocognitive Disorders; Parathyroid Glands; Parathyroid Hormone; Serum Albumin; Xanthine; Xanthines | 1991 |
Cystine uptake and glutathione level in endothelial cells exposed to oxidative stress.
Topics: Cystine; Endothelium, Vascular; Glucose; Glucose Oxidase; Glutathione; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Intracellular Membranes; Neutrophils; Oxidation-Reduction; Oxygen; Xanthine; Xanthines | 1992 |
Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia.
Topics: Asphyxia Neonatorum; Female; Fetal Blood; Fetal Monitoring; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Hypoxia; Infant, Newborn; Obstetric Labor Complications; Oxygen; Pregnancy; Purines; Risk Factors; Uric Acid; Xanthine; Xanthines | 1992 |
Increased plasma hypoxanthine values in humans during exposure to simulated altitude of 7,620 meters (25,000 feet).
Topics: Adolescent; Adult; Altitude; Atmospheric Pressure; Carbon Dioxide; Female; Hemoglobins; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Lactates; Male; Oxygen; Partial Pressure; Time Factors; Xanthine; Xanthines | 1991 |
Purine metabolites and pyrimidine bases in cerebrospinal fluid of children with simple febrile seizures.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Child, Preschool; Cytosine; Female; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Infant; Inosine; Inosine Monophosphate; Male; Purines; Pyrimidine Nucleosides; Seizures, Febrile; Thymine; Uracil; Uric Acid; Xanthine; Xanthines | 1991 |
Cellular source and role of adenosine in isoproterenol-induced coronary vasodilatation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Male; Myocardium; Oxygen Consumption; Phosphorylation; Rats; Rats, Inbred Strains; Vasodilation; Xanthine; Xanthines | 1991 |
Effect of prednisolone on urate and oxypurine excretion.
Topics: Female; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Prednisolone; Uric Acid; Xanthine; Xanthines | 1991 |
Quantitation of hypoxanthine in plasma from patients with ischemic heart disease: adaption of a high-performance liquid chromatographic method.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Coronary Disease; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Uridine; Xanthine; Xanthines | 1991 |
Purine metabolism in regenerating liver-bearing rats.
Topics: Allantoin; Animals; Hypoxanthine; Hypoxanthines; Liver Regeneration; Male; Purines; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1991 |
Prenatal diagnosis of Lesch-Nyhan syndrome by purine analysis of amniotic fluid and cordocentesis.
Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Pedigree; Pregnancy; Prenatal Diagnosis; Purines; Uric Acid; Xanthine; Xanthines | 1991 |
A novel xanthine dehydrogenase inhibitor (BOF-4272).
Topics: Allopurinol; Animals; Humans; Hypoxanthine; Hypoxanthines; Intestine, Small; Kinetics; Liver; Lung; Male; Mice; Mice, Inbred ICR; Reference Values; Species Specificity; Triazines; Urate Oxidase; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1991 |
Familial nephropathy and gout: which comes first?
Topics: Adult; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Pedigree; Reference Values; Uric Acid; Xanthine; Xanthines | 1991 |
Renal hypouricemia associated with hyperoxypurinemia due to decreased renal excretion of oxypurines: a new defect in renal purine transport.
Topics: Diet; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Tubules; Kinetics; Male; Middle Aged; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines | 1991 |
Oxypurines in extracellular fluids from piglets during hypoxemia and reoxygenation.
Topics: Animals; Extracellular Space; Hypoxanthine; Hypoxanthines; Hypoxia; Kinetics; Oxygen; Swine; Time Factors; Vitreous Body; Xanthine; Xanthines | 1991 |
Lower xanthine oxidoreductase activity in isolated perfused hearts if xanthine replaces hypoxanthine as substrate.
Topics: Animals; Guinea Pigs; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Myocardium; Perfusion; Rats; Substrate Specificity; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
A xanthinuric family--the proposita having immunologically reactive xanthine oxidase but no xanthine oxidase activity.
Topics: Female; Humans; Hypoxanthine; Hypoxanthines; Immunodiffusion; Liver; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Values; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
[A study on treatment of hyperuricemia--effects and kinetics of allopurinol and oxipurinol].
Topics: Adult; Allopurinol; Humans; Hypoxanthine; Hypoxanthines; Male; Oxypurinol; Reference Values; Uric Acid; Xanthine; Xanthines | 1991 |
Antiischemic and metabolic effects of glutamate during pacing in patients with stable angina pectoris secondary to either coronary artery disease or syndrome X.
Topics: Adult; Angina Pectoris; Cardiac Pacing, Artificial; Coronary Angiography; Coronary Disease; Electrocardiography; Fatty Acids; Heart; Hemodynamics; Humans; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Middle Aged; Myocardium; Sodium Glutamate; Syndrome; Xanthine; Xanthines | 1991 |
Changes in gastric mucosal content of adenosine, xanthine and hypoxanthine induced by restrained water immersion stress: antiulcer effects of tetraprenylacetone.
Topics: Adenine Nucleotides; Adenosine; Animals; Anti-Ulcer Agents; Diterpenes; Free Radicals; Gastric Mucosa; Hypoxanthine; Hypoxanthines; Immersion; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Time Factors; Xanthine; Xanthines | 1991 |
Sixty-minute normothermic liver ischemia in rats. Evidence that allopurinol improves liver cell energy metabolism during reperfusion but that timing of drug administration is important.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Bile; Drug Administration Schedule; Energy Metabolism; Hypoxanthine; Hypoxanthines; Liver; Male; Rats; Rats, Inbred Strains; Reperfusion Injury; Xanthine; Xanthines | 1991 |
Mechanism and prevention of ischemia-reperfusion-induced liver injury in rats.
Topics: Adenine Nucleotides; Animals; Hepatic Veins; Hypoxanthine; Hypoxanthines; Ischemia; Liver Circulation; Liver Diseases; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Reperfusion Injury; Xanthine; Xanthines | 1991 |
[The effect of aminophylline on plasma oxypurines in patients with bronchial asthma or cor pulmonale].
Topics: Adult; Aminophylline; Asthma; Female; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Pulmonary Heart Disease; Xanthine; Xanthines | 1991 |
Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury.
Topics: Adenine Nucleotides; Animals; Free Radicals; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Kidney Tubules; L-Lactate Dehydrogenase; Male; Oxygen; Rats; Rats, Inbred Strains; Reperfusion Injury; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
The pathogenesis of the Lesch-Nyhan syndrome: ATP use is positively related to hypoxanthine supply to hypoxanthine guanine phosphoribosyltransferase.
Topics: Adenosine Triphosphate; Adult; Aging; Body Mass Index; Creatinine; Exercise; Female; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lesch-Nyhan Syndrome; Male; Middle Aged; Uric Acid; Xanthine; Xanthines | 1991 |
Role of conversion of xanthine dehydrogenase to oxidase in ischemic rat liver cell injury.
Topics: Animals; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Ischemia; Lipid Peroxides; Liver; Male; Rats; Rats, Inbred Strains; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1991 |
Simultaneous determination of inosine, hypoxanthine, xanthine, and uric acid and the effect of metal chelators.
Topics: Adenosine Triphosphate; Animals; Chelating Agents; Chromatography; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lung; Male; Perfusion; Purinones; Rats; Rats, Inbred Strains; Reproducibility of Results; Sensitivity and Specificity; Time Factors; Uric Acid; Xanthine; Xanthines | 1991 |
Theophylline-induced increase in plasma uric acid--purine catabolism increased by theophylline.
Topics: Administration, Oral; Adult; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Male; Nucleotides; Purines; Theophylline; Tumor Cells, Cultured; Uric Acid; Xanthine; Xanthines | 1991 |
Quantitative analysis of the contribution of Glu46 and Asn98 to the guanosine specificity of ribonuclease T1.
Topics: Asparagine; Aspergillus oryzae; Binding Sites; DNA Mutational Analysis; Glutamates; Guanine; Guanosine; Hydrogen Bonding; Hypoxanthine; Hypoxanthines; Kinetics; Oligonucleotides; Recombinant Proteins; Ribonuclease T1; Substrate Specificity; Xanthine; Xanthines | 1991 |
Identification of xanthine and hypoxanthine as components of assembly pheromone in excreta of argasid ticks.
Topics: Animals; Chromatography, High Pressure Liquid; Feces; Female; Gas Chromatography-Mass Spectrometry; Guanine; Hypoxanthine; Hypoxanthines; Male; Pheromones; Ticks; Uric Acid; Xanthine; Xanthines | 1991 |
Hypoxanthine, xanthine, and urate in synovial fluid from patients with inflammatory arthritides.
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Synovial Fluid; Uric Acid; Xanthine; Xanthines | 1991 |
A novel mechanism of mycophenolic acid resistance in the protozoan parasite Tritrichomonas foetus.
Topics: Adenine; Animals; Cloning, Molecular; Drug Resistance; Guanine; Guanine Nucleotides; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Mutation; Mycophenolic Acid; Tritrichomonas; Xanthine; Xanthines | 1990 |
The effect of cattle breed and muscle type on discoloration and various biochemical parameters in fresh beef.
Topics: Animals; Breeding; Cattle; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Lipid Metabolism; Male; Meat; Metmyoglobin; Muscles; NAD; Oxidation-Reduction; Pigments, Biological; Sulfhydryl Compounds; Xanthine; Xanthines | 1991 |
Substrate specificity of urate transporter in rat renal brush border membranes.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Membrane; Hypoxanthine; Hypoxanthines; Kidney Cortex; Male; Microvilli; Rats; Structure-Activity Relationship; Substrate Specificity; Uric Acid; Xanthine; Xanthines | 1991 |
Xanthine and hypoxanthine in amniotic fluid during pregnancy.
Topics: Amniocentesis; Amniotic Fluid; Cell Hypoxia; Female; Fetus; Humans; Hypoxanthine; Hypoxanthines; Pregnancy; Reference Values; Rh-Hr Blood-Group System; Xanthine; Xanthines | 1990 |
Oxypurinol protects normothermic ischemic hearts.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Disease; Heart Arrest, Induced; Hypoxanthine; Hypoxanthines; Inosine; Myocardial Contraction; Myocardial Reperfusion Injury; Oxypurinol; Rabbits; Ventricular Function, Left; Xanthine; Xanthines | 1990 |
Luminol chemiluminescence using xanthine and hypoxanthine as xanthine oxidase substrates.
Topics: Animals; Cattle; Dithionite; Hypoxanthine; Hypoxanthines; Kinetics; Luminescent Measurements; Luminol; Milk; Pyridazines; Spectrophotometry, Ultraviolet; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?].
Topics: Animals; Chromatography; Free Radicals; Hypoxanthine; Hypoxanthines; Ischemia; Liver; Rats; Reperfusion; Superoxides; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1990 |
[Nucleotide metabolism in remnant rat liver after major hepatic resection].
Topics: Animals; Hepatectomy; Hypoxanthine; Hypoxanthines; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Nucleotides; Purine Nucleotides; Rats; Rats, Inbred Strains; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Avian vitreous humor concentrations of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine as influenced by age and sex: their relevance as indicators of ante-mortem hypoxia.
Topics: Age Factors; Animals; Chickens; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Postmortem Changes; Sex Factors; Uracil; Uric Acid; Uridine; Vitreous Body; Xanthine; Xanthines | 1990 |
Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection.
Topics: Animals; Blood; Brain Ischemia; Heart Arrest; Hypoglycemia; Hypoxanthine; Hypoxanthines; Hypoxia; Injections, Spinal; Insulin; Postmortem Changes; Potassium Chloride; Rats; Rats, Inbred Strains; Uridine; Xanthine; Xanthines | 1990 |
Hypoxanthine, xanthine, and uric acid concentrations in the cerebrospinal fluid, plasma, and urine of hypoxemic pigs.
Topics: Animals; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Oxygen; Swine; Uric Acid; Xanthine; Xanthines | 1990 |
Changes in oxypurine concentrations in vitreous humor of pigs during hypoxemia and post-mortem.
Topics: Animals; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Postmortem Changes; Purinones; Swine; Time Factors; Uric Acid; Vitreous Body; Xanthine; Xanthines | 1990 |
Tissue release of adenosine triphosphate degradation products during shock in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Diaphragm; Digestive System; Dogs; Hindlimb; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Oxygen; Purine Nucleotides; Renal Circulation; Shock; Xanthine; Xanthines | 1990 |
Adenosine, inosine, and hypoxanthine/xanthine measured in tissue and plasma by a luminescence method.
Topics: Adenosine; Adenosine Deaminase; Animals; Dogs; Humans; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Luminol; Pyridazines; Rabbits; Rats; Solutions; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Excretion of purine derivatives by ruminants: endogenous excretion, differences between cattle and sheep.
Topics: Allantoin; Animals; Cattle; Hypoxanthine; Hypoxanthines; Male; Purines; Sheep; Swine; Urate Oxidase; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Excretion of purine derivatives by ruminants: effect of exogenous nucleic acid supply on purine derivative excretion by sheep.
Topics: Allantoin; Animals; Bacterial Proteins; Dietary Proteins; Drug Administration Schedule; Female; Hypoxanthine; Hypoxanthines; Purines; Sheep; Uric Acid; Xanthine; Xanthines | 1990 |
Interstitial purine metabolites during regional myocardial ischemia.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dialysis; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Male; Myocardium; Osmolar Concentration; Purines; Reference Values; Time Factors; Xanthine; Xanthines | 1990 |
Impairment of the post-anoxic recovery of isolated rat hearts by intravascular hypoxanthine and xanthine.
Topics: Animals; Blood Substitutes; Free Radicals; Heart; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniques; Male; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Xanthine; Xanthines | 1990 |
60 min normothermic liver ischemia in rats: allopurinol improves energy status and bile flow during reperfusion.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Bile; Body Temperature; Energy Metabolism; Hypoxanthine; Hypoxanthines; Ischemia; Liver; Male; Osmolar Concentration; Rats; Regional Blood Flow; Time Factors; Xanthine; Xanthines | 1990 |
Xanthine oxidoreductase activity in perfused hearts of various species, including humans.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Guinea Pigs; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Ketone Oxidoreductases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Myocardium; Perfusion; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Swine; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1990 |
Protection by bepridil against myocardial ATP-catabolism is probably due to negative inotropy.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bepridil; Depression, Chemical; Energy Metabolism; Heart; Hypoxanthine; Hypoxanthines; Inosine; Male; Myocardium; Pyrrolidines; Rats; Rats, Inbred Strains; Vasodilation; Xanthine; Xanthines | 1987 |
Comparison of the effects of superoxide dismutase and cytochrome c on luminol chemiluminescence produced by xanthine oxidase-catalyzed reactions.
Topics: Catalysis; Cytochrome c Group; Hypoxanthine; Hypoxanthines; Kinetics; Luminescent Measurements; Luminol; Oxygen; Pyridazines; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1989 |
Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver.
Topics: Animals; Female; Hypoxanthine; Hypoxanthines; L-Lactate Dehydrogenase; Liver Circulation; Malondialdehyde; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1989 |
Matrix-isolation of H-induced free radicals from purines in acidic glasses.
Topics: Adenine; Electron Spin Resonance Spectroscopy; Free Radicals; Glass; Guanine; Hydrogen; Hypoxanthine; Hypoxanthines; Purines; Sulfuric Acids; Xanthine; Xanthines | 1989 |
Apparent inosine uptake by the human heart.
Topics: Adult; Cardiac Catheterization; Coronary Disease; Female; Hemodynamics; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Myocardium; Xanthine; Xanthines | 1989 |
Therapeutic criteria in hydrocephalic children.
Topics: Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Purinones; Uric Acid; Xanthine; Xanthines | 1989 |
Purine and oxypurine production in mitochondria of ischemic and reperfused myocardium.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Animals; Hypoxanthine; Hypoxanthines; Male; Malondialdehyde; Mitochondria, Heart; Myocardial Reperfusion Injury; Purines; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines | 1989 |
Uricosuric effect of irtemazole in healthy subjects.
Topics: Administration, Oral; Adult; Benzimidazoles; Glomerular Filtration Rate; Humans; Hypoxanthine; Hypoxanthines; Male; Purines; Uric Acid; Uricosuric Agents; Xanthine; Xanthines | 1989 |
[Analysis of uric acid and oxypurines in normal subjects and in gout patients].
Topics: Adult; Gout; Humans; Hypoxanthine; Hypoxanthines; Middle Aged; Uric Acid; Xanthine; Xanthines | 1989 |
[The pool of free purine and pyrimidine nucleosides and bases in the thymocytes, and splenic T- and B-lymphocytes of C3HA mice during the growth of solid hepatoma 22a].
Topics: Adenine; Adenosine; Animals; B-Lymphocytes; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthine; Hypoxanthines; Inosine; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Purine Nucleosides; Pyrimidine Nucleosides; Spleen; T-Lymphocytes; Thymus Gland; Time Factors; Xanthine; Xanthines | 1989 |
[Clearance of oxypurines in normal subjects and in gout patients subjected to a purine-free diet. Effects of allopurinol].
Topics: Adult; Allopurinol; Creatinine; Diet; Gout; Humans; Hypoxanthine; Hypoxanthines; Middle Aged; Uric Acid; Xanthine; Xanthines | 1989 |
Xanthine and hypoxanthine accumulation during storage may contribute to reperfusion injury following liver transplantation in the rat.
Topics: Animals; Cell Survival; Female; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Liver; Liver Transplantation; Perfusion; Rats; Rats, Inbred Lew; Reperfusion Injury; Time Factors; Tissue Preservation; Transplantation, Homologous; Xanthine; Xanthines | 1989 |
Renal oxypurine deposition in Lesch-Nyhan syndrome: sonographic evaluation.
Topics: Allopurinol; Child; Humans; Hypoxanthine; Hypoxanthines; Kidney Calculi; Lesch-Nyhan Syndrome; Male; Ultrasonography; Uric Acid; Xanthine; Xanthines | 1989 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extracellular Space; Hypertension; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Rats; Rats, Inbred SHR; Xanthine; Xanthines | 1989 |
Changes in lipid peroxidation and activities of xanthine oxidase, superoxide dismutase and catalase in kidneys of cephaloridine-administered rats.
Topics: Animals; Blood Urea Nitrogen; Catalase; Cephaloridine; Hypoxanthine; Hypoxanthines; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Inbred Strains; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines | 1989 |
[Purine transport through the blood-brain barrier in hypoxanthine phosphoribosyltransferase deficiency].
Topics: Adolescent; Adult; Allopurinol; Blood-Brain Barrier; Child; Child, Preschool; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Purines; Xanthine; Xanthines | 1989 |
Induction of profound hypouricemia by a non-sedating thiobarbiturate.
Topics: Antineoplastic Agents; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Serum Albumin; Thiobarbiturates; Ultrafiltration; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1989 |
Hypoxanthine in diagnosis, prognosis and pathogeny of hypoxic injury.
Topics: Amniotic Fluid; Animals; Biomarkers; Cricetinae; Female; Fetal Blood; Fetal Hypoxia; Guinea Pigs; Hypoxanthine; Hypoxanthines; Mice; Pregnancy; Prognosis; Rats; Rats, Inbred Strains; Reference Values; Species Specificity; Xanthine; Xanthines | 1989 |
Influence of perinatal hypoxia on purine contents in erythrocytes of newborn infants.
Topics: Asphyxia Neonatorum; Erythrocytes; Female; Fetal Blood; Fetal Hypoxia; Humans; Hypoxanthine; Hypoxanthines; Infant, Newborn; Inosine Monophosphate; Pregnancy; Purines; Reference Values; Uric Acid; Xanthine; Xanthines | 1989 |
Potential role of mitochondrial calcium metabolism during reperfusion injury.
Topics: Animals; Calcium; Catalase; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Male; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Reperfusion Injury; Superoxide Dismutase; Xanthine; Xanthines | 1989 |
Cerebrospinal fluid nucleotide metabolites following short febrile convulsions.
Topics: Child Development; Child, Preschool; Female; Humans; Hypoxanthine; Hypoxanthines; Infant; Male; Seizures, Febrile; Uridine; Xanthine; Xanthines | 1989 |
Cerebrospinal fluid nucleotide metabolites following non-convulsive status epilepticus.
Topics: Child; Child, Preschool; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia, Brain; Infant; Male; Seizures, Febrile; Spasms, Infantile; Status Epilepticus; Uridine; Xanthine; Xanthines | 1989 |
Cerebral uric acid, xanthine, and hypoxanthine after ischemia: the effect of allopurinol.
Topics: Allopurinol; Animals; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypoxanthine; Hypoxanthines; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1989 |
Role of xanthine oxidase inhibitor as free radical scavenger: a novel mechanism of action of allopurinol and oxypurinol in myocardial salvage.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Coronary Disease; Female; Free Radicals; Heart; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Male; Myocardium; Oxypurinol; Phosphocreatine; Pyrimidines; Swine; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Isocratic separation of ATP and its degradation products from biological fluids by automated liquid chromatography.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Autoanalysis; Body Fluids; Chromatography, Liquid; Cyclic AMP; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Xanthine; Xanthines | 1988 |
Blockade of N-methyl-D-aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Brain Ischemia; Corpus Striatum; Hypoxanthine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xanthine; Xanthines | 1986 |
Renal vasoconstriction and transient declamp hypotension after infrarenal aortic occlusion: role of plasma purine degradation products.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Aorta, Abdominal; Blood Pressure; Constriction; Dogs; Hypoxanthine; Hypoxanthines; Inosine; Male; Phentolamine; Postoperative Complications; Receptors, Adrenergic, alpha; Renal Circulation; Xanthine; Xanthines | 1988 |
Extracellular increase of hypoxanthine and xanthine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Evoked Potentials, Somatosensory; Extracellular Space; Fetus; Hypoxanthine; Hypoxanthines; Hypoxia; Sheep; Xanthine; Xanthines | 1989 |
Plasma xanthine oxidase activity correlates with the resistance to severe hypoxia in different species.
Topics: Animals; Cricetinae; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Hypoxia; Mice; Polarography; Rats; Rats, Inbred Strains; Reference Values; Species Specificity; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Brain benzodiazepine receptor binding and purine concentration in Lesch-Nyhan syndrome.
Topics: Adolescent; Adult; Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lesch-Nyhan Syndrome; Purines; Receptors, GABA-A; Synaptic Transmission; Xanthine; Xanthines | 1985 |
Hypoxanthine and xanthine in stored SAGM-blood.
Topics: Adenine; Blood Preservation; Glucose; Humans; Hypoxanthine; Hypoxanthines; Mannitol; Sodium Chloride; Time Factors; Xanthine; Xanthines | 1986 |
Renal excretion of hypoxanthine and xanthine in primary gout.
Topics: Adult; Aged; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Middle Aged; Uric Acid; Xanthine; Xanthines | 1988 |
[Early changes of oxypurines in rat brain following focal cerebral ischemia].
Topics: Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1988 |
Myocardial reperfusion injury. Role of myocardial hypoxanthine and xanthine in free radical-mediated reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Female; Free Radicals; Heart; Heart Ventricles; Hypoxanthine; Hypoxanthines; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Thioinosine; Xanthine; Xanthines | 1988 |
A kinetic study of hypoxanthine oxidation by milk xanthine oxidase.
Topics: Animals; Hypoxanthine; Hypoxanthines; Kinetics; Milk; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Molybdenum cofactor deficiency in a patient previously characterized as deficient in sulfite oxidase.
Topics: Cells, Cultured; Coenzymes; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Infant; Male; Metalloproteins; Molybdenum; Molybdenum Cofactors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines | 1988 |
Hypoxanthine, xanthine, urate and creatinine concentration gradients in cerebrospinal fluid.
Topics: Biological Transport, Active; Cisterna Magna; Creatinine; Dementia; Depression; Humans; Hypoxanthine; Hypoxanthines; Lumbosacral Region; Spinal Canal; Uric Acid; Xanthine; Xanthines | 1988 |
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex.
Topics: Adenosine; Animals; Cerebral Cortex; Coformycin; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides; Uric Acid; Xanthine; Xanthines | 1988 |
Assessment of warm ischemia time in donor kidneys by analysis of purine metabolism.
Topics: Adenine Nucleotides; Animals; Dogs; Female; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Ischemia; Kidney; Kidney Cortex; Kinetics; Male; Purines; Temperature; Xanthine; Xanthines | 1987 |
Nucleotides, nucleosides, and oxypurines in human kidneys measured by use of reversed-phase high-performance liquid chromatography.
Topics: Adenine Nucleotides; Adenosine; Chromatography, High Pressure Liquid; Coenzyme A; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Kidney Cortex; Kidney Transplantation; NAD; NADP; Nucleosides; Nucleotides; Quality Control; Xanthine; Xanthines | 1988 |
Renal excretion of purine bases. Effects of probenecid, benzbromarone and pyrazinamide.
Topics: Adult; Benzbromarone; Benzofurans; Biological Transport, Active; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Male; Probenecid; Purines; Pyrazinamide; Uric Acid; Xanthine; Xanthines | 1988 |
Transmural differences in the postischemic recovery of cardiac energy metabolism.
Topics: Adenine Nucleotides; Animals; Coronary Disease; Energy Metabolism; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Reference Values; Uric Acid; Xanthine; Xanthines | 1988 |
Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia.
Topics: Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Kidney Diseases; Male; Middle Aged; Pyrazinamide; Reference Values; Uric Acid; Xanthine; Xanthines | 1988 |
Adenine nucleotide metabolism by isolated kidney tubules during oxygen deprivation.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Allopurinol; Anaerobiosis; Animals; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Rabbits; Xanthine; Xanthines | 1988 |
Alterations in cerebrospinal fluid uridine, hypoxanthine, and xanthine in head-injured patients.
Topics: Adult; Craniocerebral Trauma; Humans; Hypoxanthine; Hypoxanthines; Uridine; Ventriculostomy; Xanthine; Xanthines | 1988 |
Purine metabolites in the CSF in presenile and senile dementia of Alzheimer type, and in multi infarct dementia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Creatinine; Dementia; Humans; Hypoxanthine; Hypoxanthines; Middle Aged; Purines; Uric Acid; Xanthine; Xanthines | 1988 |
Possible mechanism responsible for allopurinol-nephrotoxicity: lipid peroxidation and systems of producing- and scavenging oxygen radicals.
Topics: Allopurinol; Animals; Catalase; Creatinine; Free Radicals; Hypoxanthine; Hypoxanthines; Kidney Diseases; Lipid Peroxides; Male; Organ Size; Oxygen; Rats; Rats, Inbred Strains; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Purine excretion during tumor lysis in children with acute lymphocytic leukemia receiving allopurinol: relationship to acute renal failure.
Topics: Acute Kidney Injury; Allopurinol; Child; Glomerular Filtration Rate; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Lymphoid; Spectrophotometry, Infrared; Uric Acid; Xanthine; Xanthines | 1986 |
Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain Chemistry; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Ischemic Attack, Transient; Male; Nucleotides; Purines; Rats; Rats, Inbred Strains; Xanthine; Xanthines | 1987 |
The determination of urinary oxypurines as markers of gastrointestinal tumors.
Topics: Adult; Aged; Carcinoembryonic Antigen; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Rectal Neoplasms; Stomach Neoplasms; Xanthine; Xanthines | 1987 |
Chemiluminescent determination of adenosine, inosine, and hypoxanthine/xanthine.
Topics: Adenosine; Adipose Tissue; Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Inosine; Luminescent Measurements; Oxidation-Reduction; Uric Acid; Xanthine; Xanthines | 1987 |
Liquid chromatography with multichannel ultraviolet detection used for studying disorders of purine metabolism.
Topics: Adenine; Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Oxypurinol; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthine; Xanthines | 1987 |
[Mechanism of exercise-induced hyperuricemia].
Topics: Adult; Ammonia; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Physical Exertion; Purines; Uric Acid; Xanthine; Xanthines | 1987 |
Plasma oxipurinol concentrations during allopurinol therapy.
Topics: Allopurinol; Creatine; Gout; Humans; Hypoxanthine; Hypoxanthines; Kidney Function Tests; Oxypurinol; Pyrimidines; Uric Acid; Xanthine; Xanthines | 1987 |
Liquid-chromatographic determination of inosine, xanthine, and hypoxanthine in uremic patients receiving hemodialysis treatment.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Inosine; Middle Aged; Renal Dialysis; Uremia; Xanthine; Xanthines | 1987 |
Liquid-chromatographic measurements of inosine, hypoxanthine, and xanthine in studies of fructose-induced degradation of adenine nucleotides in humans and rats.
Topics: Adenine Nucleotides; Allopurinol; Animals; Chromatography, Liquid; Female; Fructose; Humans; Hypoxanthine; Hypoxanthines; Injections, Intravenous; Inosine; Male; Rats; Rats, Inbred Strains; Time Factors; Xanthine; Xanthines | 1986 |
Guanine is a growth factor for Legionella species.
Topics: Adenine; Culture Media; Cytosine; Growth Substances; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Legionella; Nucleosides; Nucleotides; Thymine; Uracil; Xanthine; Xanthines | 1986 |
Post-mortem oxypurine concentrations in the CSF.
Topics: Adult; Autopsy; Child; Female; Humans; Hypoxanthine; Hypoxanthines; Infant, Newborn; Male; Postmortem Changes; Urea; Xanthine; Xanthines | 1986 |
Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Body Fluids; Creatinine; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Middle Aged; Prospective Studies; Purines; Uric Acid; Xanthine; Xanthines | 1986 |
Regional variations in the "adenine/oxypurine" pool of the heart in normoxia and oxygen deficiency.
Topics: Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Dogs; Energy Metabolism; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine Monophosphate; Male; Myocardium; NAD; Uric Acid; Xanthine; Xanthines | 1986 |
Conversion of purines to xanthine by Methanococcus vannielii.
Topics: Euryarchaeota; Guanine; Guanine Nucleotides; Guanosine; Hypoxanthine; Hypoxanthines; Purines; Uric Acid; Xanthine; Xanthines | 1986 |
The concentrations of xanthine and hypoxanthine in cerebrospinal fluid as therapeutic guides in hydrocephalus.
Topics: Cerebrospinal Fluid Shunts; Child, Preschool; Guanine; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Xanthine; Xanthines | 1986 |
Separation of hypoxanthine and xanthine from pyrazinamide and its metabolites in plasma and urine by high-performance liquid chromatography.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Pyrazinamide; Spectrum Analysis; Xanthine; Xanthine Oxidase; Xanthines | 1986 |
[Destruction of muscle tissue and purine compound metabolism in hereditary muscular dystrophy].
Topics: Adenine Nucleotides; Animals; Hypoxanthine; Hypoxanthines; Inosine; Inosine Monophosphate; Mice; Muscles; Muscular Dystrophies; Purines; Uric Acid; Xanthine; Xanthines | 1986 |
Hereditary xanthinuria. Evidence for enhanced hypoxanthine salvage.
Topics: Adenine; Adenine Nucleotides; Adolescent; Adult; Female; Fructose; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Cellular hypoxia during hemodialysis. Demonstration of intradialytic release of purine and pyrimidine metabolites.
Topics: Adolescent; Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Kidney Failure, Chronic; Kinetics; Leukocyte Count; Male; Middle Aged; Oxygen; Purines; Pyrimidines; Renal Dialysis; Xanthine; Xanthines | 1985 |
Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Ischemia; Capillaries; Cerebral Cortex; Hypoxanthine; Hypoxanthines; Kinetics; Rats; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1985 |
Reversed-phase liquid-chromatographic determination of purine compounds in serum applied to studies of hypouricemia.
Topics: Adult; Aged; Allopurinol; Chromatography, High Pressure Liquid; Colorimetry; Female; Humans; Hypoxanthine; Hypoxanthines; Male; Metabolic Diseases; Middle Aged; Oxypurinol; Purines; Uric Acid; Xanthine; Xanthines | 1986 |
Xanthine-containing calculi during allopurinol therapy.
Topics: Adult; Allopurinol; Humans; Hypoxanthine; Hypoxanthines; Kidney Calculi; Lesch-Nyhan Syndrome; Male; Oxypurinol; Uric Acid; Xanthine; Xanthines | 1985 |
Plasma hypoxanthine and xanthine levels in the early newborn period in problem-free preterm babies and those with idiopathic respiratory distress syndrome.
Topics: Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Infant, Newborn; Infant, Premature; Prognosis; Reference Values; Respiratory Distress Syndrome, Newborn; Time Factors; Xanthine; Xanthines | 1985 |
Studies of biochemical markers in cerebrospinal fluid in patients with meningoencephalitis.
Topics: Adenylate Kinase; Adolescent; Adult; Aged; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Humans; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Leukocyte Count; Meningoencephalitis; Middle Aged; Uric Acid; Xanthine; Xanthines | 1985 |
Erythroid induction of K562 human leukemia cells: enhancement by purines.
Topics: Adenine; Cell Cycle; Cell Division; Cell Line; Drug Synergism; Guanine; Hemoglobins; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Mycophenolic Acid; Thymidine; Xanthine; Xanthines | 1985 |
Changes in acid-base status, lactate concentration and purine metabolites during reconstructive aortic surgery.
Topics: Acid-Base Equilibrium; Adenosine; Aged; Aorta, Abdominal; Aortic Aneurysm; Arteriosclerosis; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Middle Aged; Purines; Xanthine; Xanthines | 1985 |
Increased concentration of hypoxanthine in human central cerebrospinal fluid after subarachnoid haemorrhage.
Topics: Adult; Aged; Hemoglobinometry; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Intracranial Aneurysm; Intracranial Pressure; Middle Aged; Prognosis; Subarachnoid Hemorrhage; Uric Acid; Xanthine; Xanthines | 1985 |
Evidence for adenosine triphosphate degradation in critically-ill patients.
Topics: Adenosine; Adenosine Triphosphate; Blood Pressure; Cardiac Output; Critical Care; Female; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Oxygen; Prognosis; Vasoconstrictor Agents; Xanthine; Xanthines | 1985 |
Hypouricemia and renal tubular acidosis in primary biliary cirrhosis.
Topics: Acidosis, Renal Tubular; Female; Humans; Hypoxanthine; Hypoxanthines; Liver Cirrhosis, Biliary; Middle Aged; Pyrazinamide; Uric Acid; Xanthine; Xanthines | 1985 |
Purine and monoamine metabolites in cerebrospinal fluid: parallel purinergic and monoaminergic activation in depressive illness?
Topics: Adult; Aged; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypoxanthine; Hypoxanthines; Male; Methoxyhydroxyphenylglycol; Middle Aged; Phenylacetates; Xanthine; Xanthines | 1983 |
Depression and somatosensory evoked potentials: I. Correlations between SEP and monoamine and purine metabolites in CSF.
Topics: Adult; Depressive Disorder; Evoked Potentials, Somatosensory; Female; Fingers; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypoxanthine; Hypoxanthines; Male; Methoxyhydroxyphenylglycol; Phenylacetates; Somatosensory Cortex; Touch; Xanthine; Xanthines | 1983 |
Enhanced ATP and GTP synthesis from hypoxanthine or inosine after myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Inosine; Male; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1984 |
Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Azathioprine; DNA; Guanine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Xanthine; Xanthines | 1984 |
Killing of human malaria parasites by macrophage secretory products.
Topics: Animals; Free Radicals; Glucose Oxidase; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Macrophage Activation; Macrophages; Plasmodium falciparum; Rabbits; Xanthine; Xanthine Oxidase; Xanthines | 1984 |
Pregnancy in xanthinuria: demonstration of fetal uric acid production?
Topics: Adult; Female; Fetus; Humans; Hypoxanthine; Hypoxanthines; Middle Aged; Pregnancy; Pregnancy Complications; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid; Xanthine; Xanthines | 1984 |
Ethanol-induced activation of adenine nucleotide turnover. Evidence for a role of acetate.
Topics: Acetates; Acetic Acid; Adenine; Adenine Nucleotides; Adenosine; Adult; Carbon Radioisotopes; Ethanol; Humans; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Time Factors; Xanthine; Xanthines | 1984 |
Hypoxanthine and xanthine concentrations determined by high performance liquid chromatography in biological fluids from patients with xanthinuria.
Topics: Adult; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Male; Middle Aged; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid; Xanthine; Xanthines | 1984 |
[Assay of plasma xanthine and hypoxanthine by coupled gas chromatography-mass spectrometry and sampling problems].
Topics: Anticoagulants; Blood Proteins; Erythrocytes; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Humans; Hypoxanthine; Hypoxanthines; Plasma; Time Factors; Xanthine; Xanthines | 1984 |
Uptake of uric acid, xanthine and hypoxanthine by brush-border membrane vesicles from mouse small intestine.
Topics: Animals; Chromatography, High Pressure Liquid; Glucose; Hypoxanthine; Hypoxanthines; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Microvilli; Phenylalanine; Purines; Time Factors; Uric Acid; Xanthine; Xanthines | 1984 |
The relationship of Cladosporium carrionii to Cladophialophora ajelloi.
Topics: Animals; Caseins; Chromoblastomycosis; Cladosporium; Gelatin; Humans; Hypoxanthine; Hypoxanthines; Mitosporic Fungi; Terminology as Topic; Tyrosine; Urease; Xanthine; Xanthines | 1984 |
Concentrations of hypoxanthine, xanthine, uridine and urate in amniotic fluid at caesarean section and the association of raised levels with prenatal risk factors and fetal distress.
Topics: Amniotic Fluid; Cesarean Section; Female; Fetal Distress; Fetal Hypoxia; Humans; Hypertension; Hypoxanthine; Hypoxanthines; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Risk; Uric Acid; Uridine; Xanthine; Xanthines | 1983 |
[Changes of the acid-base status, serum lactate concentration and purine metabolism in reconstructive arterial surgery].
Topics: Acid-Base Equilibrium; Adenosine; Aorta, Abdominal; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Middle Aged; Purines; Pyruvates; Pyruvic Acid; Uric Acid; Xanthine; Xanthines | 1983 |
Fluorometric determination of hypoxanthine and xanthine in biological fluids by high-performance liquid chromatography using enzyme reactors.
Topics: Chromatography, High Pressure Liquid; Enzymes, Immobilized; Humans; Hypoxanthine; Hypoxanthines; Peroxidases; Xanthine; Xanthine Oxidase; Xanthines | 1983 |
The excretion of 14C-hypoxanthine and its metabolites in rats following administration of uricostatic drugs.
Topics: Allantoin; Allopurinol; Animals; Carbon Radioisotopes; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1984 |
Pulse radiolysis study of hypoxanthine and xanthine oxidation.
Topics: Hypoxanthine; Hypoxanthines; Kinetics; Oxidation-Reduction; Pulse Radiolysis; Xanthine; Xanthines | 1984 |
Effect of hypoxia and exercise on nucleotide metabolism in man.
Topics: Adenosine Triphosphate; Adult; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Kinetics; Male; Muscles; Physical Exertion; Purines; Time Factors; Xanthine; Xanthines | 1984 |
The Ca-antagonist nifedipine reduces purine nucleoside and oxypurine release from ischemic heart.
Topics: Adenine Nucleotides; Animals; Coronary Circulation; Coronary Disease; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Kinetics; Myocardium; Nifedipine; Purine Nucleosides; Rats; Xanthine; Xanthines | 1984 |
Diltiazem administered before or during myocardial ischemia decreases adenine nucleotide catabolism.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Benzazepines; Coronary Circulation; Coronary Disease; Diltiazem; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines | 1984 |
Simultaneous determination of allopurinol, oxipurinol, hypoxanthine and xanthine in biological fluids by high-performance liquid chromatography.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; Hypoxanthines; Oxypurinol; Pyrimidines; Xanthine; Xanthines | 1984 |
Effects of timolol on adenine nucleotide catabolism in cat hearts with acute regional ischaemia.
Topics: Acute Disease; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Coronary Circulation; Coronary Disease; Female; Heart Rate; Hypoxanthine; Hypoxanthines; Inosine; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Timolol; Xanthine; Xanthines | 1984 |
Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.
Topics: Adolescent; Brain Diseases, Metabolic; Brain Ischemia; Child; Child, Preschool; Energy Metabolism; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Intracranial Pressure; Sleep, REM; Xanthine; Xanthines | 1984 |
[Current therapy: combined drug therapy of hyperuricemia, gout and alcohol induced fatty liver].
Topics: Allopurinol; Benzbromarone; Benzofurans; Drug Therapy, Combination; Fatty Liver, Alcoholic; Gout; Humans; Hypoxanthine; Hypoxanthines; Uric Acid; Xanthine; Xanthines | 1983 |
The determination of purine levels in human and mouse plasma.
Topics: Allopurinol; Animals; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Methods; Mice; Mice, Inbred DBA; Purines; Species Specificity; Xanthine; Xanthine Oxidase; Xanthines | 1982 |
High-performance liquid chromatographic determination of hypoxanthine and xanthine in biological fluids.
Topics: Allopurinol; Chromatography, High Pressure Liquid; Erythrocytes; Gout; Humans; Hypoxanthine; Hypoxanthines; Xanthine; Xanthine Oxidase; Xanthines | 1982 |
Effect of NADH on hypoxanthine hydroxylation by native NAD+-dependent xanthine oxidoreductase of rat liver, and the possible biological role of this effect.
Topics: Animals; Hydroxylation; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Ketone Oxidoreductases; Kinetics; Liver; Male; NAD; Rats; Rats, Inbred Strains; Spectrophotometry; Time Factors; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines | 1981 |
Adenine, the precursor of nucleic acids in intestinal cells unable to synthesize purines de novo.
Topics: Adenine; Animals; Epithelium; Guanine; Hepatectomy; Hypoxanthine; Hypoxanthines; Intestinal Mucosa; Male; Purines; Rats; Xanthine; Xanthines | 1981 |
DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals.
Topics: Adenine; Bronchi; Cell Line; DNA; DNA Damage; Epithelium; Guanine; Humans; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Smoke; Smoking; Xanthine; Xanthines | 1995 |
When does the lung die? Time course of high energy phosphate depletion and relationship to lung viability after "death".
Topics: Adenine Nucleotides; Animals; Cell Survival; Death; Energy Metabolism; Hypoxanthine; Hypoxanthines; Lung; Oxygen; Postmortem Changes; Rats; Rats, Sprague-Dawley; Time Factors; Xanthine; Xanthines | 1995 |
The effect of partial hepatectomy on blood purine levels in rats and patients.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; DNA; Hemangioma; Hepatectomy; Humans; Hypoxanthine; Hypoxanthines; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Regeneration; Male; Mitotic Index; Purines; Rats; Rats, Wistar; Species Specificity; Time Factors; Uric Acid; Xanthine; Xanthines | 1994 |
Abnormal purine and pyrimidine metabolism in inherited superactivity of PRPP synthetase.
Topics: Adenine Nucleotides; Allopurinol; Child; Erythrocytes; Female; Guanine Nucleotides; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; NAD; Nuclear Family; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Values; Ribonucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid; Uridine; Uridine Diphosphate Glucose; Xanthine; Xanthines | 1994 |
Treatment of Lesch-Nyhan syndrome with AICAR.
Topics: Adolescent; Aminoimidazole Carboxamide; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Lesch-Nyhan Syndrome; Leukemia; Male; Oxypurinol; Ribonucleotides; Uric Acid; Xanthine; Xanthines | 1994 |
Plasma and urinary oxypurines in Lesch-Nyhan patient after allopurinol treatment.
Topics: Child; Erythrocytes; Fibroblasts; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Male; Purines; Uric Acid; Xanthine; Xanthines | 1994 |
Purine metabolism in female patients with primary gout.
Topics: Adenine; Arthritis, Gouty; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Purines; Radioisotope Dilution Technique; Reference Values; Sex Characteristics; Uric Acid; Xanthine; Xanthines | 1994 |
Extracellular concentrations of oxypurines in xanthine oxidase-deficient hepatoma-derived cell line HuH-7.
Topics: 5'-Nucleotidase; Adenine Phosphoribosyltransferase; Adenosine Deaminase; Carcinoma, Hepatocellular; Cell Line; Culture Media; Cytosol; Guanine Deaminase; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Liver; Liver Neoplasms; Purine-Nucleoside Phosphorylase; Tumor Cells, Cultured; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Simultaneous determination of guanine, uric acid, hypoxanthine and xanthine in human plasma by reversed-phase high-performance liquid chromatography with amperometric detection.
Topics: Calibration; Chromatography, High Pressure Liquid; Electrochemistry; Guanine; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1995 |
Effect of glucose infusion on the renal transport of purine bases and oxypurinol.
Topics: Adult; Allopurinol; Biological Transport, Active; Diabetes Complications; Diabetes Mellitus; Glucose; Gout; Half-Life; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Kidney; Male; Mannitol; Oxypurinol; Purines; Uric Acid; Xanthine; Xanthines | 1995 |
Changes in apnea and autoresuscitation in piglets after intravenous and intrathecal interleukin-1 beta injection.
Topics: Animals; Animals, Newborn; Apnea; beta-Endorphin; Female; Heart Rate; Hypoxanthine; Hypoxanthines; Injections, Intravenous; Injections, Spinal; Interleukin-1; Male; Random Allocation; Respiratory Mechanics; Swine; Vitreous Body; Xanthine; Xanthines | 1994 |
Effects of combined cold and hyperbaric oxygen storage on free flap survival.
Topics: Animals; Cold Temperature; Glucosephosphate Dehydrogenase; Glutathione Reductase; Hyperbaric Oxygenation; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Sprague-Dawley; Surgical Flaps; Time Factors; Tissue Preservation; Tissue Survival; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Comparison of energy metabolism in rat liver grafts during preservation in University of Wisconsin or Euro-Collins solutions.
Topics: Adenosine; Allopurinol; Animals; Energy Metabolism; Glutathione; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Inosine; Insulin; Lactates; Liver; Liver Transplantation; Male; Microdialysis; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid; Xanthine; Xanthines | 1995 |
A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases.
Topics: Adult; Allantoin; Creatine Kinase; Female; Humans; Hypoxanthine; Hypoxanthines; Isoenzymes; Male; Myocardial Infarction; Myocardial Ischemia; Reference Values; Uric Acid; Xanthine; Xanthines | 1994 |
Purine metabolism in women with primary gout.
Topics: Aged; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Prospective Studies; Purines; Sex Factors; Uric Acid; Xanthine; Xanthines | 1994 |
Pentostatin-augmented interstitial adenosine prevents postcardioplegia injury in damaged hearts.
Topics: Adenosine; Animals; Creatine Kinase; Dogs; Heart Arrest, Induced; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Microdialysis; Models, Biological; Myocardial Reperfusion Injury; Pentostatin; Peroxidase; Premedication; Stroke Volume; Ventricular Function, Left; Xanthine; Xanthines | 1994 |
Determination of purine bases and nucleosides by conventional and, microbore high-performance liquid chromatography and gas chromatography with an ion-trap detector.
Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Feces; Gas Chromatography-Mass Spectrometry; Guanine; Hypoxanthine; Hypoxanthines; Ions; Ticks; Xanthine; Xanthines | 1994 |
Toxoplasma gondii: characterization of a mutant resistant to 6-thioxanthine.
Topics: Animals; Cells, Cultured; Ethylnitrosourea; Fibroblasts; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Mutagenesis; Toxoplasma; Xanthine; Xanthines | 1994 |
Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration.
Topics: Adenosine; Animals; Animals, Newborn; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Extracellular Space; Hypercapnia; Hypoglycemia; Hypoxanthine; Hypoxanthines; Inosine; Swine; Xanthine; Xanthines | 1994 |
Studies on the purine-pyrimidine metabolism (2)--Effects of sample preparation and diet on the concentrations of oxypurines in blood and urine.
Topics: Chromatography, High Pressure Liquid; Diet; Humans; Hypoxanthine; Hypoxanthines; Male; Pseudouridine; Purines; Pyrimidines; Specimen Handling; Uric Acid; Uridine; Xanthine; Xanthines | 1994 |
Fibre-optic biosensor for hypoxanthine and xanthine based on a chemiluminescence reaction.
Topics: Biosensing Techniques; Buffers; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Luminescent Measurements; Xanthine; Xanthines | 1994 |
Morphologic and metabolic study of the effect of oxygenated perfluorochemical perfusion on amputated rabbit limbs.
Topics: Adenine Nucleotides; Amputation, Surgical; Animals; Blood Substitutes; Capillaries; Endothelium, Vascular; Energy Metabolism; Fluorocarbons; Hindlimb; Hypothermia, Induced; Hypoxanthine; Hypoxanthines; Ischemia; Microscopy, Electron; Muscles; Organ Preservation; Perfusion; Rabbits; Reperfusion Injury; Replantation; Xanthine; Xanthines | 1994 |
Hypoxanthine, xanthine, and uric acid concentrations in plasma, cerebrospinal fluid, vitreous humor, and urine in piglets subjected to intermittent versus continuous hypoxemia.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Infant; Male; Sudden Infant Death; Swine; Uric Acid; Vitreous Body; Xanthine; Xanthines | 1993 |
High adenosine content in human uterine smooth muscle compared with striated skeletal muscle.
Topics: Adenosine; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Middle Aged; Myometrium; Phosphates; Postmenopause; Pregnancy; Rectus Abdominis; Xanthine; Xanthines | 1993 |
Influence of daily drinking habits on ethanol-induced hyperuricemia.
Topics: Acetates; Adult; Alcohol Drinking; Humans; Hypoxanthine; Hypoxanthines; Lactates; Male; Time Factors; Uric Acid; Xanthine; Xanthines | 1994 |
Interstitial purine metabolites and lactate during regional myocardial hypoxia.
Topics: Adenosine; Animals; Cardiomyopathies; Coronary Circulation; Dialysis; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Oxygen Consumption; Purines; Xanthine; Xanthines | 1993 |
Transport of hypoxanthine from plasma to cerebrospinal fluid and vitreous humor in newborn pigs.
Topics: Animals; Animals, Newborn; Biological Transport; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Kinetics; Swine; Uric Acid; Vitreous Body; Xanthine; Xanthines | 1993 |
Concentrations of nucleotides, nucleosides, purine bases and urate in cerebrospinal fluid of children with meningitis.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adolescent; Child; Child, Preschool; Female; Humans; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Male; Meningitis; Meningitis, Bacterial; Meningitis, Viral; Nucleosides; Nucleotides; Tuberculosis, Meningeal; Uric Acid; Xanthine; Xanthines | 1993 |
Indicators of hypoxia in cerebrospinal fluid of hydrocephalic children with suspected shunt malfunction.
Topics: Adolescent; Adult; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Equipment Failure; Female; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Hypoxia; Infant; Male; Postoperative Complications; Purines; Xanthine; Xanthines | 1993 |
Effects of asphyxia on the fetal lamb brain.
Topics: Animals; Blood Pressure; Brain; Brain Edema; Cerebellum; Cerebrovascular Circulation; Female; Fetal Hypoxia; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Oxygen; Pregnancy; Sheep; Xanthine; Xanthines | 1993 |
Energy economy in the pregnant human uterus at term: studies on arteriovenous differences in metabolites of carbohydrate, fat and nucleotides.
Topics: Adult; Arteries; Blood Glucose; Carbohydrates; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Lipids; Middle Aged; Nucleotides; Pregnancy; Pyruvates; Pyruvic Acid; Uterus; Veins; Xanthine; Xanthines | 1993 |
Exchange of purines in human liver and skeletal muscle with short-term exhaustive exercise.
Topics: Adult; Humans; Hypoxanthine; Hypoxanthines; Inosine; Liver; Male; Muscles; Oxygen Consumption; Physical Endurance; Physical Exertion; Purines; Time Factors; Uric Acid; Xanthine; Xanthines | 1994 |
Effect of DL-sodium lactate infusion on excretion of purine bases and oxypurinol.
Topics: Adult; Allopurinol; Humans; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Male; Oxypurinol; Purines; Serum Albumin; Uric Acid; Xanthine; Xanthines | 1993 |
Hypoxanthine, xanthine, and uric acid in newborn pigs during hypoxemia followed by resuscitation with room air or 100% oxygen.
Topics: Air; Animals; Animals, Newborn; Cardiopulmonary Resuscitation; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Oxygen Inhalation Therapy; Prospective Studies; Resuscitation; Swine; Uric Acid; Vitreous Body; Xanthine; Xanthines | 1993 |
[Value of oxypurines and uric acid in plasma, renal excretion of oxypurines and uric acid as well as plasma adenosine deaminase and AMP deaminase activity in patients with essential hypertension].
Topics: Adenosine Deaminase; Adult; AMP Deaminase; Female; Humans; Hypertension; Hypoxanthine; Hypoxanthines; Kidney; Male; Middle Aged; Reference Values; Uric Acid; Xanthine; Xanthines | 1993 |
Characterization of the alterations in purine nucleotide metabolism in hypoxanthine-guanine phosphoribosyltransferase-deficient rat neuroma cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Formates; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Neuroma; Purine Nucleotides; Rats; Tumor Cells, Cultured; Xanthine; Xanthines | 1993 |
A high-performance liquid chromatographic method for the determination of hypoxanthine, xanthine, uric acid and allantoin in serum.
Topics: Adolescent; Adult; Aged; Allantoin; Child; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1993 |
Effect of physical exercise on the content of 8-hydroxydeoxyguanosine in nuclear DNA prepared from human lymphocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Creatinine; Deoxyguanosine; DNA; DNA Damage; Hematocrit; Humans; Hypoxanthine; Hypoxanthines; Lymphocytes; Oxidation-Reduction; Running; Swimming; Uric Acid; Xanthine; Xanthines | 1993 |
Kinetic determination of serum adenosine deaminase.
Topics: 2,6-Dichloroindophenol; Adenosine; Adenosine Deaminase; Autoanalysis; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Pentosyltransferases; Reference Values; Spectrophotometry; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Adenine nucleotides of ischemic intestine do not reflect injury.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Hot Temperature; Hypoxanthine; Hypoxanthines; Intestinal Diseases; Intestinal Mucosa; Intestines; Ischemia; Kinetics; Male; NAD; NADP; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors; Xanthine; Xanthines | 1993 |
Effect of lactate infusion on renal transport of purine bases and oxypurinol.
Topics: Adult; Allopurinol; Biological Transport, Active; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Kidney; Lactates; Lactic Acid; Male; Oxypurinol; Purines; Serum Albumin; Uric Acid; Xanthine; Xanthines | 1993 |
Effectiveness of thrombolysis is associated with a time-dependent increase of malondialdehyde in peripheral blood of patients with acute myocardial infarction.
Topics: Adenosine; Chromatography, High Pressure Liquid; Female; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Thrombolytic Therapy; Time Factors; Uric Acid; Xanthine; Xanthines | 1993 |
In vitro and ex vivo xanthine oxidoreductase activity in rat and guinea-pig hearts using hypoxanthine or xanthine as substrate.
Topics: Animals; Guinea Pigs; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Myocardium; Perfusion; Rats; Rats, Wistar; Substrate Specificity; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase; Xanthines | 1993 |
Nitrogen metabolism during liver regeneration.
Topics: Allantoin; Amino Acids; Animals; Creatine; Hepatectomy; Hypoxanthine; Hypoxanthines; Liver; Liver Regeneration; Nitrogen; Organ Size; Rats; Rats, Wistar; Urea; Uric Acid; Xanthine; Xanthines | 1993 |
Post-mortem concentrations of hypoxanthine in the vitreous humor--a comparison between babies with severe respiratory failure, congenital abnormalities of the heart, and victims of sudden infant death syndrome.
Topics: Heart Defects, Congenital; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Infant; Infant, Newborn; Postmortem Changes; Respiratory Distress Syndrome, Newborn; Sudden Infant Death; Time Factors; Vitreous Body; Xanthine; Xanthines | 1993 |
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.
Topics: Adenine; Bacterial Infections; Chromatography, High Pressure Liquid; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Infant, Newborn; Inosine; Predictive Value of Tests; Purines; Seizures; Uric Acid; Xanthine; Xanthines | 1995 |
Responses of blood and plasma lactate and plasma purine concentrations to maximal exercise and their relation to performance in standardbred trotters.
Topics: Allantoin; Animals; Chromatography, High Pressure Liquid; Erythrocyte Count; Female; Hemoglobins; Horses; Hypoxanthine; Hypoxanthines; Lactates; Male; Physical Conditioning, Animal; Purines; Uric Acid; Xanthine; Xanthines | 1995 |
Purine metabolite washout and platelet aggregation at reflow after tourniquet ischemia: effect of intravenous regional lidocaine.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Hypoxanthine; Hypoxanthines; Ischemia; Leg; Lidocaine; Male; Middle Aged; Platelet Aggregation; Reperfusion; Tourniquets; Xanthine; Xanthines | 1995 |
[Urate production in a porcine model of myocardial ischemia-reperfusion].
Topics: Animals; Female; Free Radicals; Hypoxanthine; Hypoxanthines; Myocardial Reperfusion Injury; Myocardium; Swine; Uric Acid; Xanthine; Xanthines | 1996 |
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.
Topics: Adult; Brain Ischemia; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Intervertebral Disc Displacement; Middle Aged; Multiple Sclerosis; Nervous System Diseases; Purine Nucleotides; Reference Values; Subarachnoid Hemorrhage; Uric Acid; Xanthine; Xanthines | 1996 |
Simultaneous determination of adenosine, inosine, hypoxanthine, xanthine, and uric acid in microdialysis samples using microbore column high-performance liquid chromatography with a diode array detector.
Topics: Adenosine; Animals; Calibration; Chromatography, High Pressure Liquid; Dogs; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Microdialysis; Myocardial Reperfusion Injury; Sensitivity and Specificity; Time Factors; Uric Acid; Xanthine; Xanthines | 1996 |
Comparison of capillary electrophoretic and liquid chromatographic determination of hypoxanthine and xanthine for the diagnosis of xanthinuria.
Topics: Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Hypoxanthine; Hypoxanthines; Purine-Pyrimidine Metabolism, Inborn Errors; Xanthine; Xanthines | 1996 |
Influence of oxygen free radicals and free radical scavengers on the growth behaviour and oxidative tissue damage of bovine retinal pigment epithelium cells in vitro.
Topics: Animals; Catalase; Cattle; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Free Radical Scavengers; Free Radicals; Hypoxanthine; Hypoxanthines; Lipid Peroxidation; Lipid Peroxides; Pigment Epithelium of Eye; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Xanthine; Xanthines | 1996 |
[The effect of an alpha-tocopherol analog, MDL 73404, on myocardial bioenergetics].
Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Animals; Cardiovascular Agents; Energy Metabolism; Female; Free Radical Scavengers; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Myocardium; Phosphates; Rats; Rats, Wistar; Vitamin E; Xanthine; Xanthines | 1996 |
Determination of human plasma xanthine oxidase activity by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ethanol; Glycogen Storage Disease Type I; Gout; Heparin; Hepatitis C; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Pterins; Spectrometry, Fluorescence; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines; Xanthopterin | 1996 |
Does the internal thoracic artery graft delay the recovery of myocardial metabolism?
Topics: Adenine Nucleotides; Adenosine; Coronary Artery Bypass; Female; Heart Arrest, Induced; Humans; Hypoxanthine; Inosine; Male; Middle Aged; Myocardium; Saphenous Vein; Thoracic Arteries; Vascular Patency; Xanthine; Xanthines | 1996 |
Combined deficiency of xanthine oxidase and sulphite oxidase due to a deficiency of molybdenum cofactor.
Topics: Coenzymes; Female; Fibroblasts; Humans; Hypoxanthine; Infant; Metabolism, Inborn Errors; Metalloproteins; Molybdenum; Molybdenum Cofactors; Nervous System Diseases; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Hypoxanthine and xanthine levels in human aqueous humor from cataractous eyes.
Topics: Aqueous Humor; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Male; Spectrophotometry, Ultraviolet; Xanthine; Xanthines | 1996 |
Kainate-evoked release of adenosine from the hippocampus of the anaesthetised rat: possible involvement of free radicals.
Topics: Adenosine; Animals; Free Radicals; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Amino Acid; Time Factors; Xanthine; Xanthines | 1997 |
Assessment of xanthine oxidase in human lung and lung transplantation.
Topics: Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Free Radicals; Heart-Lung Transplantation; Humans; Hypoxanthine; Lactoferrin; Lung; Lung Transplantation; Middle Aged; Postoperative Complications; Reperfusion Injury; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Effect of glucagon on renal excretion of oxypurinol and purine bases.
Topics: Adult; Blood Glucose; Chlorine; Creatinine; Cyclic AMP; Glucagon; Humans; Hypoxanthine; Kidney; Male; Nitrogen; Oxypurinol; Phosphates; Purinones; Sodium; Uric Acid; Xanthine; Xanthines | 1997 |
Effect of ethanol and fructose on plasma uridine and purine bases.
Topics: Adult; Alcohol Drinking; Ethanol; Fructose; Humans; Hypoxanthine; Infusions, Intravenous; Lactates; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvates; Uric Acid; Uridine; Xanthine; Xanthines | 1997 |
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines | 1997 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Biological; Phosphoribosyl Pyrophosphate; Purines; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthines | 1997 |
Role of ATP-sensitive K+ channels in ischemic preconditioning of skeletal muscle against infarction.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Energy Metabolism; Hypoxanthine; Infarction; Ischemic Preconditioning; Muscle, Skeletal; Phosphocreatine; Potassium Channels; Pyrroles; Reperfusion; Surgical Flaps; Swine; Vasodilator Agents; Xanthine; Xanthines | 1997 |
Phosphocreatine content in single fibers of human muscle after sustained submaximal exercise.
Topics: Adult; Ammonia; Biopsy; Blood Glucose; Exercise; Glycogen; Heart Rate; Humans; Hypoxanthine; Lactates; Male; Muscle Fatigue; Muscle Fibers, Skeletal; Muscle, Skeletal; Oxygen Consumption; Phosphates; Phosphocreatine; Sports; Uric Acid; Xanthine; Xanthines | 1997 |
Indices of oxidative stress in urine of patients undergoing coronary artery bypass grafting.
Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthine; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Reperfusion Injury; Serum Albumin; Uric Acid; Xanthine | 1997 |
Antioxidants and dipyridamole inhibit HIV-1 gp120-induced free radical-based oxidative damage to human monocytoid cells.
Topics: Anti-HIV Agents; Antioxidants; Dipyridamole; Dose-Response Relationship, Drug; HIV Antibodies; HIV Envelope Protein gp120; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Hypoxanthine; Monocytes; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured; Xanthine | 1997 |
May peripheral and central fatigue be correlated? Can we monitor them by means of clinical laboratory tools?
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Biomarkers; Chromatography, High Pressure Liquid; Fatigue; Fatty Acids; Follow-Up Studies; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Hypoxanthine; Immunoenzyme Techniques; Inosine; Male; Muscle Fatigue; Phenylalanine; Physical Exertion; Purines; Serotonin; Tryptophan; Tyrosine; Xanthine | 1997 |
Xanthinuria in a family of Cavalier King Charles spaniels.
Topics: Animals; Breeding; Chromatography, High Pressure Liquid; Dog Diseases; Dogs; Female; Hypoxanthine; Male; Pedigree; Renal Insufficiency; Urethral Obstruction; Uric Acid; Urinary Calculi; Xanthine | 1997 |
Fetal oxygen saturation monitoring in labour: an analysis of 118 cases.
Topics: Adolescent; Adult; Apgar Score; Female; Fetal Blood; Fetal Monitoring; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Infant, Newborn; Labor, Obstetric; Oximetry; Oxygen; Pregnancy; Xanthine | 1997 |
Ischemia induces significant changes in purine nucleoside concentration in the retina-choroid in rats.
Topics: Adenosine; Animals; Choroid; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Ischemia; Purine Nucleosides; Rats; Rats, Sprague-Dawley; Regression Analysis; Retina; Retinal Artery Occlusion; Time Factors; Vitreous Body; Xanthine | 1997 |
Molybdenum cofactor deficiency-phenotypic variability in a family with a late-onset variant.
Topics: Age of Onset; Behavioral Symptoms; Brain; Child; Diagnosis, Differential; Family Relations; Female; Humans; Hypoxanthine; Infant; Lens Subluxation; Magnetic Resonance Imaging; Molybdenum; Oxidoreductases Acting on Sulfur Group Donors; Phenotype; Purine-Pyrimidine Metabolism, Inborn Errors; Uric Acid; Xanthine | 1998 |
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Epilepsy; Female; Glutamic Acid; Humans; Hypoxanthine; L-Lactate Dehydrogenase; Lactic Acid; Male; Meningitis, Viral; Middle Aged; Multiple Sclerosis; Serum Albumin; Spinal Cord Diseases; Uric Acid; Xanthine | 1997 |
Oxidative stress induced by bloodless limb surgery on humans.
Topics: Aged; Arthroplasty, Replacement, Knee; Blood Loss, Surgical; Glutathione; Hemoglobins; Humans; Hypoxanthine; Knee; Oxidation-Reduction; Oxidative Stress; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
[Mechanisms of disturbances of hypoxanthine metabolism in the liver of resuscitated rats].
Topics: Animals; Hypoxanthine; Liver; Male; Rats; Resuscitation; Xanthine | 1997 |
Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Energy Metabolism; Excitatory Amino Acids; Glutamic Acid; Hypoxanthine; Hypoxia; Malondialdehyde; Rats; Rats, Wistar; Xanthine | 1998 |
Response of purine metabolism and cortical oxygen pressure to hypoxia and reoxygenation in newborn piglets.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Hypoxanthine; Hypoxia; Inosine; Oxygen; Partial Pressure; Purines; Swine; Uric Acid; Xanthine | 1997 |
Simultaneous measurement of allantoin, uric acid, xanthine and hypoxanthine in blood by high-performance liquid chromatography.
Topics: Allantoin; Animals; Chromatography, High Pressure Liquid; Hydrazones; Hypoxanthine; Indicators and Reagents; Phenylhydrazines; Quality Control; Sensitivity and Specificity; Sheep; Uric Acid; Xanthine | 1997 |
Purine metabolism of uric acid urolithiasis induced in newborn piglets.
Topics: Aging; Allantoin; Animals; Animals, Newborn; Body Weight; Hypoxanthine; Purines; Swine; Swine Diseases; Uric Acid; Urinary Calculi; Xanthine | 1998 |
Circulating xanthine oxidase and neutrophil activation during human liver transplantation.
Topics: Adult; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypoxanthine; Intraoperative Period; Lactoferrin; Liver Circulation; Liver Transplantation; Male; Middle Aged; Neutrophil Activation; Postoperative Period; Reperfusion; Uric Acid; Xanthine; Xanthine Oxidase | 1998 |
Changes in purine metabolism and production of oxygen free radicals by intermittent partial umbilical cord occlusion in chronically instrumented fetal lambs.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain; Fetal Hypoxia; Hydrogen-Ion Concentration; Hypoxanthine; Inosine Monophosphate; Microdialysis; Oxidative Stress; Reactive Oxygen Species; Sheep; Superoxides; Time Factors; Umbilical Cord; Xanthine | 1998 |
[Metabolism of purine compounds in psoriasis].
Topics: Adenosine Deaminase; Chromatography, High Pressure Liquid; Humans; Hypoxanthine; N-Glycosyl Hydrolases; Psoriasis; Purine-Nucleoside Phosphorylase; Purines; Skin; Uric Acid; Xanthine | 1998 |
The effects of nucleotide pool on purine production in the postischemic heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines; Rats; Time Factors; Uric Acid; Xanthine | 1998 |
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleotides; Rats; Temperature; Time Factors; Uric Acid; Xanthine | 1998 |
Capillary electrophoretic analysis of hypoxanthine and xanthine for the diagnosis of xanthinuria.
Topics: Adult; Biomarkers; Electrophoresis, Capillary; Humans; Hypoxanthine; Infant, Newborn; Purine-Pyrimidine Metabolism, Inborn Errors; Reference Values; Xanthine | 1998 |
Hypoxanthine and xanthine as markers in early diagnosis of foetal diseases.
Topics: Adult; Amniotic Fluid; Biomarkers; Chromatography, High Pressure Liquid; False Positive Reactions; Female; Fetal Diseases; Humans; Hypoxanthine; Maternal Age; Predictive Value of Tests; Pregnancy; Pregnancy, High-Risk; Prenatal Diagnosis; Xanthine | 1998 |
Determination and separation of allantoin, uric acid, hypoxanthine, and xanthine by capillary zone electrophoresis.
Topics: Allantoin; Electrophoresis, Capillary; Humans; Hypoxanthine; Reproducibility of Results; Sensitivity and Specificity; Uric Acid; Xanthine | 1998 |
Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum.
Topics: Adenine; Animals; Autoradiography; Binding, Competitive; Cell Line; Cryptosporidium parvum; Dogs; Formates; Glycine; Guanine; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Pentosyltransferases; Spores; Xanthine | 1998 |
Xylitol-induced increase in the plasma concentration and urinary excretion of uridine and purine bases.
Topics: Adult; Humans; Hypoxanthine; Injections, Intravenous; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvic Acid; Uric Acid; Uridine; Xanthine; Xylitol | 1998 |
Oxidative damage to proteins, lipids, and DNA in cortical brain regions from patients with dementia with Lewy bodies.
Topics: Adenine; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Cerebral Cortex; Cytosine; DNA; Guanine; Humans; Hydantoins; Hypoxanthine; Lewy Bodies; Lipid Peroxidation; Middle Aged; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Thymine; Uracil; Xanthine | 1998 |
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; Hemodynamics; Hypoxanthine; Hypoxia; Inosine; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Potassium Channels; Uric Acid; Xanthine | 1998 |
Loss of endothelium-derived nitric oxide in rabbit aorta by oxidant stress: restoration by superoxide dismutase mimetics.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Ditiocarb; Endothelium, Vascular; Free Radical Scavengers; Hypoxanthine; In Vitro Techniques; Male; Metalloporphyrins; Molecular Mimicry; Muscle Relaxation; Nitric Oxide; Oxidative Stress; Rabbits; Superoxide Dismutase; Xanthine | 1998 |
Effect of bucladesine sodium on the plasma concentrations and urinary excretion of purine bases and uridine.
Topics: Adult; Blood Glucose; Bucladesine; Glucagon; Humans; Hypoxanthine; Insulin; Male; Middle Aged; Uric Acid; Uridine; Xanthine | 1998 |
Interstitial ATP level and degradation in control and postmyocardial infarcted rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Heart; Hypoxanthine; In Vitro Techniques; Inosine; Intracellular Fluid; Male; Microdialysis; Myocardial Contraction; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Time Factors; Xanthine | 1998 |
Inhibition of calcitriol-induced monocyte CD14 expression by uremic toxins: role of purines.
Topics: Calcitriol; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Humans; Hypoxanthine; Lipopolysaccharide Receptors; Monocytes; Purines; Statistics, Nonparametric; Toxins, Biological; Up-Regulation; Uremia; Uric Acid; Xanthine | 1998 |
Uneven regional distribution of nucleotide metabolism in human brain.
Topics: Adenosine; Brain; Brain Chemistry; Cerebellar Cortex; Cerebral Cortex; Humans; Hypoxanthine; Myelin Sheath; Nucleotides; Organ Specificity; Thalamus; Uridine; Xanthine | 1998 |
Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8,11,14-Eicosatrienoic Acid; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Copper; Cysteine; Dihydroxyphenylalanine; Dopamine; Glutathione; Humans; Hypoxanthine; Iron; Parkinson Disease; Reactive Oxygen Species; Reference Values; Superoxides; Xanthine | 1998 |
Purine metabolism in female heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Female; Heterozygote; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Male; Middle Aged; Purines; Spain; Xanthine | 1998 |
Muscle anaerobic response to a maximal treadmill exercise test in Standardbred trotters.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biopsy; Breeding; Energy Metabolism; Exercise Test; Female; Glycogen; Heart Rate; Horses; Hypoxanthine; Inosine Monophosphate; Lactates; Male; Muscle, Skeletal; Phosphocreatine; Physical Conditioning, Animal; Uric Acid; Xanthine | 1998 |
Effects of metabolic flux on stress response pathways in Lactococcus lactis.
Topics: ATP-Binding Cassette Transporters; Carbon; Cell Survival; Escherichia coli Proteins; Genes, Bacterial; Guanine; Guanine Nucleotides; Guanosine; Heat-Shock Proteins; Hydrogen Peroxide; Hypoxanthine; Inosine; Lactococcus lactis; Metabolism; Molecular Sequence Data; Mutagenesis, Insertional; Periplasmic Binding Proteins; Phosphate-Binding Proteins; Phosphates; Rec A Recombinases; Temperature; Time Factors; Xanthine | 1999 |
Low myometrial glycogen content compared with rectus muscle in term pregnant women before labor.
Topics: Adenosine; Adult; Cesarean Section; Energy Metabolism; Female; Glucose; Glycogen; Humans; Hypoxanthine; Labor, Obstetric; Myometrium; Pregnancy; Rectus Abdominis; Xanthine | 1999 |
Plasma hypoxanthine levels during crystalloid and blood cardioplegias: warm blood cardioplegia increases hypoxanthine levels with a greater risk of oxidative stress.
Topics: Aged; Aged, 80 and over; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Heart Arrest, Induced; Humans; Hypoxanthine; Male; Middle Aged; Oxidative Stress; Retrospective Studies; Xanthine | 1999 |
Delayed impairment of cerebral oxygenation after deep hypothermic circulatory arrest in children.
Topics: Brain; Female; Heart Arrest, Induced; Heart Defects, Congenital; Hemoglobins; Humans; Hypothermia, Induced; Hypoxanthine; Infant; Infant, Newborn; Lactoferrin; Male; Neutrophil Activation; Oxygen; Postoperative Period; Time Factors; Xanthine | 1999 |
Can oxypurines plasma levels classify the type of physical exercise?
Topics: Ammonia; Analysis of Variance; Chromatography, High Pressure Liquid; Exercise; Humans; Hypoxanthine; Inosine; Lactic Acid; Muscle Fatigue; Uric Acid; Xanthine | 1999 |
Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries.
Topics: Animals; Arteries; Brain; Capillaries; Constriction; Female; Fetus; Hypoxanthine; Ischemia; Ovary; Pregnancy; Rats; Rats, Wistar; Reperfusion; Thiobarbituric Acid Reactive Substances; Uric Acid; Uterus; Xanthine; Xanthine Oxidase | 1999 |
Purine catabolism: links to mitochondrial respiration and antioxidant defenses?
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Guanine; Guanosine; Hypoxanthine; Kinetics; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Purines; Rats; Reference Values; Uric Acid; Xanthine | 1999 |
Plasma hypoxanthine and ammonia in humans during prolonged exercise.
Topics: Adenine Nucleotides; Adult; Ammonia; Exercise; Heart Rate; Humans; Hypoxanthine; Inosine Monophosphate; Kinetics; Lactic Acid; Male; Muscles; Oxygen Consumption; Physical Endurance; Uric Acid; Xanthine | 1999 |
Pharmacokinetics and pharmacodynamics of allopurinol in elderly and young subjects.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Allopurinol; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Hypoxanthine; Male; Oxypurinol; Time Factors; Uric Acid; Xanthine | 1999 |
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
Topics: Allopurinol; Biological Transport; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Febuxostat; Humans; Hypoxanthine; Inosine; Lung Neoplasms; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Pentosyltransferases; Purines; Pyrimidine Phosphorylases; Thiazoles; Tumor Cells, Cultured; Uracil; Uridine; Xanthine; Xanthine Oxidase | 2000 |
Expression of antioxidant enzymes in human inflammatory cells.
Topics: Adenosine Diphosphate; Catalase; Cell Survival; Energy Metabolism; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Hypoxanthine; Leukocytes, Mononuclear; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Respiratory Burst; RNA, Messenger; Superoxide Dismutase; Uric Acid; Xanthine | 2000 |
Effect of ACTH on renal excretion of purine bases in a patient with isolated ACTH deficiency.
Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Cosyntropin; Gonadotropins, Pituitary; Humans; Hypoxanthine; Infusions, Intravenous; Kidney; Male; Middle Aged; Pituitary Hormone-Releasing Hormones; Renin; Uric Acid; Xanthine | 2000 |
A simple high-performance liquid chromatography assay for simultaneous measurement of adenosine, guanosine, and the oxypurine metabolites in plasma.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Guanosine; Humans; Hypoxanthine; Inosine; Purines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Uric Acid; Xanthine | 2000 |
Urinary hypoxanthine and xanthine levels in acute coronary syndromes.
Topics: Acute Disease; Adult; Aged; Angina, Unstable; Biomarkers; Blood Urea Nitrogen; Creatine; Female; Humans; Hypoxanthine; Male; Middle Aged; Myocardial Ischemia; Purines; Uric Acid; Xanthine | 1999 |
Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats.
Topics: Analysis of Variance; Animals; Body Water; Bradykinin Receptor Antagonists; Brain Chemistry; Brain Edema; Brain Injuries; Glutamic Acid; Hypoxanthine; Injections, Subcutaneous; Kinins; Male; Neuroprotective Agents; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Taurine; Xanthine | 2000 |
Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Escherichia coli; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Kinetics; Molecular Sequence Data; Molecular Weight; Phosphoribosyl Pyrophosphate; Plasmodium falciparum; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Xanthine | 2000 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine | 2000 |
Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro.
Topics: Air Pollutants; Allopurinol; Animals; Breast; Cytosol; Dicumarol; Female; Fluorenes; Hypoxanthine; Indomethacin; Microsomes; Niacinamide; Oxidation-Reduction; Oxygen; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rutin; Vitamin K; Xanthine | 2000 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine | 2000 |
Quantification of allantoin, uric acid, xanthine and hypoxanthine in ovine urine by high-performance liquid chromatography and photodiode array detection.
Topics: Allantoin; Animals; Chromatography, High Pressure Liquid; Hypoxanthine; Quality Control; Reproducibility of Results; Sheep; Uric Acid; Xanthine | 2000 |
Measurement of purines in urine by capillary electrophoresis for estimating the degree of hypoxia in infants.
Topics: Buffers; Calibration; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxia; Infant; Infant, Newborn; Reference Standards; ROC Curve; Sensitivity and Specificity; Uric Acid; Xanthine | 2000 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Hypoxanthine; Inosine; Ischemia; Male; Norepinephrine; Rats; Rats, Wistar; Spleen; Sympathectomy; Sympathetic Nervous System; Sympathomimetics; Tetrodotoxin; Tritium; Vasodilator Agents; Xanthine | 2000 |
Effect of creatine supplementation on muscle metabolic response to a maximal treadmill exercise test in Standardbred horses.
Topics: Animals; Blood Volume; Creatine; Creatinine; Dietary Supplements; Exercise Test; Heart Rate; Horses; Hypoxanthine; Lactic Acid; Male; Muscles; Physical Conditioning, Animal; Uric Acid; Xanthine | 2000 |
Plasma purine turnover metabolites in women with normal pregnancy and pregnancy complicated with induced hypertension as compared to fetal well-being indices.
Topics: Adult; Apgar Score; Blood Pressure; Diastole; Female; Gestational Age; Heart Rate, Fetal; Humans; Hypertension; Hypoxanthine; Infant, Newborn; Inosine; Pregnancy; Pregnancy Complications, Cardiovascular; Purines; Systole; Uric Acid; Xanthine | 2000 |
Glutamate and catabolites of high-energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese.
Topics: Aging; Animals; Brain Stem; Corpus Striatum; Energy Metabolism; Glutamic Acid; Hypoxanthine; Male; Manganese; Osmolar Concentration; Phosphates; Rats; Rats, Wistar; Time Factors; Uric Acid; Xanthine | 2000 |
Glutathione deficiency potentiates manganese-induced increases in compounds associated with high-energy phosphate degradation in discrete brain areas of young and aged rats.
Topics: Aging; Animals; Antimetabolites; Ascorbic Acid; Brain; Buthionine Sulfoximine; Dehydroascorbic Acid; Drug Synergism; Energy Metabolism; Glutathione; Hypoxanthine; Inosine; Male; Manganese; Phosphates; Rats; Rats, Wistar; Tissue Distribution; Uric Acid; Xanthine | 2000 |
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase | 2001 |
Changes in fetal plasma adenosine and xanthine concentrations during fetal asphyxia with maternal oxygen administration in ewes.
Topics: Adenosine; Animals; Asphyxia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Female; Fetal Hypoxia; Heart Rate; Hypoxanthine; Oxygen; Sheep; Xanthine | 2000 |
Determination of purine compounds in carotid artery plaque by liquid chromatography electrospray ionization tandem mass spectrometry.
Topics: Aged; Allantoin; Arteriosclerosis; Carotid Arteries; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Male; Purines; Spectrometry, Mass, Electrospray Ionization; Uric Acid; Xanthine | 2001 |
Identification of a new point mutation in the human xanthine dehydrogenase gene responsible for a case of classical type I xanthinuria.
Topics: Allopurinol; Humans; Hypoxanthine; Male; Middle Aged; Oxypurinol; Point Mutation; Purine-Pyrimidine Metabolism, Inborn Errors; Sequence Analysis, DNA; Xanthine; Xanthine Dehydrogenase | 2001 |
Hepatic xanthine levels as viability predictor of livers procured from non-heart-beating donor pigs.
Topics: Animals; Energy Metabolism; Graft Survival; Heart Arrest; Hypoxanthine; Liver; Liver Transplantation; Logistic Models; Survival Rate; Swine; Tissue and Organ Procurement; Tissue Donors; Xanthine | 2001 |
Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii.
Topics: Archaeoglobus; Bacterial Proteins; Base Sequence; Deoxyribonuclease I; Enzyme Stability; Escherichia coli; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Hydrolysis; Hypoxanthine; Inosine Triphosphate; Methanococcus; Nucleotides; Oligonucleotides; Protein Denaturation; Pyrophosphatases; Substrate Specificity; Temperature; Xanthine | 2001 |
The effect of allopurinol on focal cerebral ischaemia: an experimental study in rabbits.
Topics: Allopurinol; Animals; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Hematocrit; Hemoglobins; Hypoxanthine; Infarction, Middle Cerebral Artery; Rabbits; Uric Acid; Xanthine; Xanthine Oxidase | 2001 |
Effect of norepinephrine on the urinary excretion of purine bases and oxypurinol.
Topics: Adult; Blood Pressure; Chlorides; Humans; Hypoxanthine; Injections, Intravenous; Male; Middle Aged; Norepinephrine; Oxypurinol; Potassium; Purines; Sodium; Time Factors; Uric Acid; Xanthine | 2001 |
Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes.
Topics: Albumins; Allopurinol; Animals; Bilirubin; Blood Pressure; Fasting; Female; Heme; Hypertension; Hypoxanthine; Kidney; Liver; Pentoxifylline; Platelet Count; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Sheep; Uric Acid; Xanthine | 2001 |
Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function.
Topics: Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthine; Kidney; Kidney Diseases; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Reperfusion Injury; Uric Acid; Xanthine | 2001 |
Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes.
Topics: Adenine; Alleles; Amino Acid Substitution; Aspergillus nidulans; Binding, Competitive; Biological Transport; Fungal Proteins; Genes, Fungal; Hypoxanthine; Kinetics; Membrane Transport Proteins; Purines; Solubility; Structure-Activity Relationship; Substrate Specificity; Suppression, Genetic; Uracil; Urea; Uric Acid; Xanthine | 2001 |
Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.
Topics: Adenine; Adenoviruses, Human; Animals; Cell Line; Cell Survival; Gene Transfer Techniques; Genetic Vectors; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Mice; Uric Acid; Uridine Diphosphate Glucose; Xanthine | 2000 |
Purines, lactate and myo-inositol in CSF might reflect excitotoxicity in inherited metabolic disorders.
Topics: Child; Child, Preschool; Glutamic Acid; Humans; Hypoxanthine; Infant; Inositol; Lactates; Metabolism, Inborn Errors; Purines; Receptors, Glutamate; Uric Acid; Uridine; Xanthine | 2000 |
Oxidative stress to human lymphocytes by xanthine oxidoreductase activity.
Topics: Apoptosis; Catalase; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; DNA Fragmentation; Flow Cytometry; Humans; Hypoxanthine; Lymphocytes; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Superoxide Dismutase; Time Factors; Transglutaminases; Xanthine | 2001 |
Oxidative stress in the fetal lamb brain following intermittent umbilical cord occlusion: a path analysis.
Topics: Animals; Brain; Fetus; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxia; Lipid Peroxidation; Oxidative Stress; Sheep; Umbilical Cord; Uric Acid; Xanthine | 2001 |
Effect of inosine on the plasma concentration of uridine and purine bases.
Topics: Adult; Carcinoma, Hepatocellular; Creatinine; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Inosine; Kinetics; Liver Neoplasms; Purines; Reference Values; Time Factors; Tumor Cells, Cultured; Uric Acid; Uridine; Xanthine | 2002 |
Oxypurines, protein, glucose and the functional state of blood vasculature are markers of renal calcium stone-forming processes? Observations in men with idiopathic recurrent calcium urolithiasis.
Topics: Adult; Age Factors; Aged; Blood Glucose; Blood Vessels; Body Weight; Calcium Oxalate; Chemistry, Clinical; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Kidney Calculi; Male; Middle Aged; Proteinuria; Purines; Time Factors; Xanthine | 2002 |
Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury?
Topics: Angioplasty, Balloon, Coronary; Animals; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Cyclosporine; Dinoprost; Epinephrine; Free Radical Scavengers; Heart Arrest; Hypoxanthine; Lactic Acid; Nervous System Diseases; Saline Solution, Hypertonic; Swine; Treatment Outcome; Vasoconstrictor Agents; Vasopressins; Xanthine | 2002 |
A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis.
Topics: Animals; Catalysis; Guanine; Hypoxanthine; Models, Molecular; Mutagenesis, Site-Directed; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Plasmodium falciparum; Protein Structure, Tertiary; Structure-Activity Relationship; Xanthine | 2002 |
An in vitro hydroxyl radical generation assay for microdialysis sampling calibration.
Topics: Ascorbic Acid; Calibration; Chromatography, High Pressure Liquid; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Microdialysis; Uric Acid; Xanthine; Xanthine Oxidase | 2002 |
Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide.
Topics: Fluorescent Dyes; Hypoxanthine; Kinetics; Myoglobin; Nitrates; Nitric Oxide; Oxidation-Reduction; Superoxides; Xanthine; Xanthine Oxidase | 2002 |
Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems.
Topics: Animals; Cattle; Enzymes; Erythrocytes; Guanine; Guanosine; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Inosine; Kinetics; Models, Chemical; Molecular Structure; Protein Binding; Purine-Nucleoside Phosphorylase; Ribonucleosides; Spleen; Structure-Activity Relationship; Substrate Specificity; Xanthine; Xanthines | 2002 |
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hyperkalemia; Hypothermia; Hypoxanthine; Inosine; L-Lactate Dehydrogenase; Lactates; Myocardium; Purines; Reperfusion Injury; Temperature; Time Factors; Xanthine | 2002 |
[HPLC determination of uracil xanthine, hypoxanthine and uridine in species of animal drugs].
Topics: Animals; Chromatography, High Pressure Liquid; Hypoxanthine; Insecta; Materia Medica; Uracil; Uridine; Xanthine | 1999 |
Effect of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism in healthy subjects.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Enalapril; Humans; Hypoxanthine; Losartan; Male; Oxypurinol; Uric Acid; Xanthine | 2002 |
The effect of transient intestinal ischemia on inflammatory parameters.
Topics: Aged; Aortic Aneurysm, Abdominal; Biomarkers; Colitis, Ischemic; Cytokines; Eicosanoids; Humans; Hypoxanthine; Inflammation Mediators; Intestinal Mucosa; Italy; Leukocyte Count; Middle Aged; Neutrophils; Phagocytosis; Reperfusion; Surgical Instruments; von Willebrand Factor; Xanthine; Xanthine Oxidase | 2003 |
[The comparison of contents of uracil, xanthine and hypoxanthine in five species of leech].
Topics: Animals; Chromatography, High Pressure Liquid; Hypoxanthine; Leeches; Materia Medica; Uracil; Xanthine | 1999 |
Energy demands during a judo match and recovery.
Topics: Adolescent; Adult; Ammonia; Creatinine; Diet; Energy Metabolism; Heart Rate; Humans; Hypoxanthine; Lactates; Lipids; Male; Martial Arts; Oxygen Consumption; Urea; Uric Acid; Xanthine | 2003 |
31P NMR studies of energy metabolism in xanthosine-5'-monophosphate overproducing Corynebacterium ammoniagenes.
Topics: Adenine Nucleotides; Corynebacterium; Energy Metabolism; Escherichia coli; Glutamic Acid; Hypoxanthine; Kinetics; Magnetic Resonance Spectroscopy; Phosphorus; Ribonucleotides; Xanthine | 2003 |
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.
Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine | 2003 |
Biosynthesis of nucleic acid purines. II. Role of hypoxanthine and xanthine compounds.
Topics: Hypoxanthine; Nucleic Acids; Purines; Xanthine; Xanthines | 1955 |
Enzymic determination of hypoxanthine and xanthine in human plasma and urine.
Topics: Blood; Body Fluids; Humans; Hypoxanthine; Urine; Xanthine; Xanthines | 1955 |
Hypoxanthine and xanthine accumulated in stored human blood: determination of the relative amounts by spectrophotometry.
Topics: Blood; Humans; Hypoxanthine; Spectrophotometry; Xanthine; Xanthines | 1955 |
On accumulation of hypoxanthine plus xanthine in withdrawn human blood.
Topics: Blood; Humans; Hypoxanthine; Xanthine; Xanthines | 1955 |
[Spectrophotometric determination of a mixture of hypoxanthine, xanthine, uric acid & 6-mercaptopurine].
Topics: Humans; Hypoxanthine; Hypoxanthines; Mercaptopurine; Spectrophotometry; Uric Acid; Xanthine; Xanthines | 1957 |
Uric acid, xanthine and hypoxanthine in the cerebrospinal fluid.
Topics: Humans; Hypoxanthine; Hypoxanthines; Uric Acid; Xanthine; Xanthines | 1957 |
[Hypoxanthine & xanthine in seminal vesicles].
Topics: Biochemical Phenomena; Humans; Hypoxanthine; Male; Seminal Vesicles; Xanthine; Xanthines | 1957 |
PURINE METABOLISM BY UNICELLULAR ALGAE. II. ADENINE, HYPOXANTHINE, AND XANTHINE DEGRADATION BY CHORELLA PYRENOIDOSA.
Topics: Adenine; Allantoin; Biochemical Phenomena; Chromatography; Eukaryota; Hypoxanthine; Hypoxanthines; Metabolism; Research; Spectrophotometry; Uric Acid; Xanthine; Xanthines | 1964 |
Interstitial purine metabolites in hearts with LV remodeling.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Hypoxanthine; Inosine; Isoproterenol; Kinetics; Male; Microdialysis; Models, Animal; Purines; Rats; Rats, Wistar; Uric Acid; Ventricular Function, Left; Ventricular Remodeling; Xanthine | 2004 |
Uric acid and allantoin levels in Down syndrome: antioxidant and oxidative stress mechanisms?
Topics: Adolescent; Aging; Allantoin; Antioxidants; Child; Chromatography, High Pressure Liquid; Down Syndrome; Female; Humans; Hypoxanthine; Indicators and Reagents; Male; Oxidative Stress; Reference Standards; Spectrophotometry, Ultraviolet; Uric Acid; Xanthine | 2004 |
[Effect of optimum jogging in a hot environment on uric acid metabolism].
Topics: Adult; Circadian Rhythm; Hot Temperature; Humans; Hypoxanthine; Jogging; Male; Muscle, Skeletal; Purine Nucleotides; Seasons; Time Factors; Uric Acid; Xanthine | 2004 |
Inhibition of Na+, K+-ATPase activity in rat striatum by the metabolites accumulated in Lesch-Nyhan disease.
Topics: Analysis of Variance; Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hypoxanthine; In Vitro Techniques; Kinetics; Lesch-Nyhan Syndrome; Linear Models; Rats; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Uric Acid; Xanthine | 2004 |
Transcription of purine transporter genes is activated during the isotropic growth phase of Aspergillus nidulans conidia.
Topics: Aspergillus nidulans; Blotting, Northern; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Hypoxanthine; Membrane Transport Proteins; Mycelium; Nucleobase Transport Proteins; Purines; Spores, Fungal; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Xanthine | 2004 |
Protective effects of exogenous fructose-1,6-biphosphate during small bowel transplantation in rats.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Bacterial Translocation; Cryopreservation; Cytoprotection; Fructosediphosphates; Glutathione; Hypoxanthine; Insulin; Intestine, Small; Intestines; L-Lactate Dehydrogenase; Male; Organ Preservation Solutions; Oxidative Stress; Raffinose; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Uric Acid; Xanthine | 2004 |
Physiological and metabolic actions of mycophenolate mofetil on cultured newborn rat cardiomyocytes in normoxia and in simulated ischemia.
Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Hypoxanthine; Immunosuppressive Agents; Membrane Potentials; Mycophenolic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocytes, Cardiac; Rats; Rats, Wistar; Xanthine | 2004 |
Effect of sauna bathing and beer ingestion on plasma concentrations of purine bases.
Topics: Adult; Beer; Creatinine; Humans; Hypoxanthine; Male; Purines; Steam Bath; Uric Acid; Xanthine | 2004 |
Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase.
Topics: Animals; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA Glycosylases; DNA Polymerase beta; DNA, Single-Stranded; Guanine; Humans; Hypoxanthine; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Nucleotides; Oligonucleotides; Protein Binding; Purine Nucleosides; Spleen; Swine; Thymus Gland; Time Factors; Xanthine | 2004 |
Increase of uricogenesis in the kuruma shrimp Marsupenaeus japonicus reared under hyper-osmotic conditions.
Topics: Ammonia; Animals; Epidermis; Gills; Hepatopancreas; Hypoxanthine; Osmosis; Penaeidae; Sodium Chloride; Urate Oxidase; Urea; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 2004 |
[Xanthinuria with xanthine lithiasis in a patient with Lesch-Nyhan syndrome under allopurinol therapy].
Topics: Allopurinol; Child; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Hypoxanthine; Kidney Calculi; Lesch-Nyhan Syndrome; Male; Uric Acid; Xanthine | 2004 |
Urinary excretion of purine derivatives as an index of microbial protein synthesis in the camel (Camelus dromedarius).
Topics: Allantoin; Animals; Bacterial Proteins; Camelus; Diet; Duodenum; Fasting; Female; Hypoxanthine; Purines; Rumen; Uric Acid; Xanthine; Xanthine Oxidase | 2004 |
A new synthesis of the purines adenine, hypoxanthine, xanthine, and isoguanine.
Topics: Adenine; Guanine; Hypoxanthine; Purines; Xanthine; Xanthines | 1950 |
Determination of urinary S-sulphocysteine, xanthine and hypoxanthine by liquid chromatography-electrospray tandem mass spectrometry.
Topics: Adult; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Chromatography, Liquid; Coenzymes; Cysteine; Humans; Hypoxanthine; Infant; Infant, Newborn; Metalloproteins; Molybdenum Cofactors; Oxidoreductases Acting on Sulfur Group Donors; Pteridines; Spectrometry, Mass, Electrospray Ionization; Xanthine | 2005 |
[Determination of hypoxanthine and xanthine in hippocampus by HPLC method].
Topics: Animals; Chromatography, High Pressure Liquid; Hypoxanthine; Materia Medica; Pharmacognosy; Quality Control; Smegmamorpha; Xanthine | 2002 |
[Oxypurine].
Topics: Humans; Hypoxanthine; Xanthine | 2004 |
Identification and characterization of purine nucleoside transporters from Crithidia fasciculata.
Topics: Adenosine; Amino Acid Sequence; Animals; Cloning, Molecular; Crithidia fasciculata; Culture Media; Genome, Protozoan; Guanosine; Hypoxanthine; Inosine; Molecular Sequence Data; Nucleoside Transport Proteins; Open Reading Frames; Protozoan Proteins; Purine Nucleosides; Sequence Alignment; Xanthine | 2005 |
An increase of uricogenesis in the Kuruma shrimp Marsupenaeus japonicus under nitrite stress.
Topics: Ammonia; Animals; Enzyme Activation; Gills; Hepatopancreas; Hypoxanthine; Nitrites; Penaeidae; Taiwan; Urate Oxidase; Urea; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 2005 |
Mediation of the effect of nicotine on Kir6.1 channels by superoxide anion production.
Topics: ATP-Binding Cassette Transporters; Cell Line; Cyclic N-Oxides; Dose-Response Relationship, Drug; Drug Synergism; Humans; Hypoxanthine; KATP Channels; Membrane Potentials; Nicotine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Reactive Oxygen Species; Spin Labels; Superoxides; Transfection; Xanthine | 2005 |
Deactivation of triplet-excited riboflavin by purine derivatives: important role of uric acid in light-induced oxidation of milk sensitized by riboflavin.
Topics: Animals; Electron Transport; Hydrogen-Ion Concentration; Hypoxanthine; Light; Milk; Oxidation-Reduction; Photolysis; Purines; Riboflavin; Solutions; Thermodynamics; Uric Acid; Xanthine | 2005 |
Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma.
Topics: Adenosine; Aged; Aged, 80 and over; Anterior Eye Segment; Aqueous Humor; Blotting, Northern; Cell Culture Techniques; Chromatography, High Pressure Liquid; Exfoliation Syndrome; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Hypoxanthine; Immunohistochemistry; In Situ Hybridization; Inosine; Receptor, Adenosine A3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Xanthine | 2005 |
Determination of uric acid and p-aminohippuric acid in human saliva and urine using capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of renal disease.
Topics: Ascorbic Acid; Electrochemistry; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Kidney Diseases; p-Aminohippuric Acid; Reproducibility of Results; Saliva; Sensitivity and Specificity; Uric Acid; Xanthine | 2005 |
Three-way partial least-squares regression for the simultaneous kinetic-enzymatic determination of xanthine and hypoxanthine in human urine.
Topics: Humans; Hypoxanthine; Kinetics; Least-Squares Analysis; Oxidation-Reduction; Principal Component Analysis; Spectrophotometry, Ultraviolet; Xanthine; Xanthine Oxidase | 2005 |
Extracellular H2O2 and not superoxide determines the compartment-specific activation of transferrin receptor by iron regulatory protein 1.
Topics: Animals; Blotting, Western; Catalase; Cells, Cultured; Electrophoretic Mobility Shift Assay; Fibroblasts; Glucose Oxidase; Hydrogen Peroxide; Hypoxanthine; Iron Regulatory Protein 1; Mice; Reactive Oxygen Species; Receptors, Transferrin; RNA, Messenger; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase | 2005 |
Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.
Topics: Animals; Animals, Newborn; Brain; Electroencephalography; Guanosine; Hemorrhage; Hypotension; Hypoxanthine; Inosine; Oxygen Consumption; Purines; Pyrimidines; Sheep Diseases; Uridine; Xanthine | 2006 |
Comparison of four markers for quantifying microbial protein flow from the rumen of lactating dairy cows.
Topics: Amino Acids; Animals; Bacteria; Biomarkers; Cattle; Chromatography, High Pressure Liquid; Diet; Dietary Proteins; Digestion; Eukaryota; Female; Glycine max; Hypoxanthine; Lactation; Nitrogen; Nitrogen Isotopes; Proteins; Purines; Rumen; Sensitivity and Specificity; Xanthine | 2005 |
Effects of long-term beer ingestion on plasma concentrations and urinary excretion of purine bases.
Topics: Adult; Alcohol Drinking; Beer; Ethanol; Gout; Humans; Hypoxanthine; Kidney Concentrating Ability; Male; Purines; Uric Acid; Xanthine | 2005 |
Role of aspartate 143 in Escherichia coli tRNA-guanine transglycosylase: alteration of heterocyclic substrate specificity.
Topics: Amino Acid Substitution; Anticodon; Aspartic Acid; Escherichia coli Proteins; Hypoxanthine; Kinetics; Mutation; Pentosyltransferases; Serine; Substrate Specificity; Threonine; Xanthine | 2006 |
Reclassification of Amycolatopsis orientalis DSM 43387 as Amycolatopsis benzoatilytica sp. nov.
Topics: Actinomycetales; Caseins; Fatty Acids; Gelatin; Humans; Hydrolysis; Hypoxanthine; Lactose; Lipids; Molecular Sequence Data; Mycetoma; Neck; Polysorbates; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Homology, Nucleic Acid; Species Specificity; Xanthine | 2006 |
[Identification of 5 constituents of the aqueous extract of Isatis indigotica by HPLC-MS2].
Topics: Chromatography, High Pressure Liquid; Cytidine; Guanosine; Hot Temperature; Hypoxanthine; Isatis; Plants, Medicinal; Uridine; Water; Xanthine | 2005 |
Quantification of uric acid, xanthine and hypoxanthine in human serum by HPLC for pharmacodynamic studies.
Topics: Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Hypoxanthine; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthine Oxidase | 2006 |
Effects of allopurinol on beer-induced increases in plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine).
Topics: Adult; Allopurinol; Beer; Ethanol; Humans; Hypoxanthine; Lactic Acid; Male; Oxypurinol; Purines; Uric Acid; Uridine; Xanthine | 2006 |
Potential artifacts in the measurement of DNA deamination.
Topics: Amination; Animals; Artifacts; Cattle; Chromatography, High Pressure Liquid; Disease Models, Animal; DNA; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hypoxanthine; Jurkat Cells; Lipopolysaccharides; Nitric Oxide; Oxidative Stress; Rats; Sepsis; Xanthine | 2006 |
Increased plasma concentrations of activin a predict intraventricular hemorrhage in preterm newborns.
Topics: Activins; Biomarkers; Cerebral Hemorrhage; Cerebral Ventricles; Fetal Blood; Humans; Hypoxanthine; Infant, Newborn; Infant, Premature; Inhibin-beta Subunits; Predictive Value of Tests; ROC Curve; Xanthine | 2006 |
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy.
Topics: Aged; Cardiomyopathies; Cardiotonic Agents; Enzyme Inhibitors; Female; Humans; Hypoxanthine; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Oxypurinol; Reactive Oxygen Species; Uric Acid; Xanthine; Xanthine Oxidase | 2006 |
Efficacy and safety of allopurinol in patients with the Lesch-Nyhan syndrome and partial hypoxanthine- phosphoribosyltransferase deficiency: a follow-up study of 18 Spanish patients.
Topics: Adolescent; Adult; Allopurinol; Child; Child, Preschool; Follow-Up Studies; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Infant; Lesch-Nyhan Syndrome; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Spain; Uric Acid; Xanthine | 2006 |
Effect of beer ingestion on the plasma concentrations and urinary excretion of purine bases: one-month study.
Topics: Acetic Acid; Alcohol Drinking; Beer; Ethanol; Humans; Hypoxanthine; Liver; Male; Purines; Time Factors; Uric Acid; Xanthine | 2006 |
Purine catabolism in advanced carotid artery plaque.
Topics: Aged; Aged, 80 and over; Allantoin; Allopurinol; Carotid Stenosis; Chemistry, Clinical; Female; Free Radicals; Humans; Hypoxanthine; Male; Middle Aged; Oxidants; Oxypurinol; Purines; Uric Acid; Xanthine | 2006 |
Simultaneous determination of allantoin, hypoxanthine, xanthine, and uric acid in serum/plasma by CE.
Topics: Allantoin; Chronic Disease; Electrophoresis, Capillary; Heart Diseases; Humans; Hypoxanthine; Kidney Failure, Chronic; Oxidative Stress; Renal Dialysis; Uric Acid; Xanthine | 2007 |
A potential prebiotic route to adenine from hypoxanthine.
Topics: Adenine; Glycine; Guanine; Hypoxanthine; Molecular Structure; Urea; Xanthine | 2005 |
Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.
Topics: Adult; Biomarkers; Cadaver; Female; Humans; Hypoxanthine; Kidney; Kidney Transplantation; Male; Middle Aged; Purine Nucleosides; Renal Veins; Reperfusion Injury; Tissue Donors; Transplantation, Homologous; Xanthine | 2007 |
On-line automatic SPE-CE coupling for the determination of biological markers in urine.
Topics: Adolescent; Adult; Ascorbic Acid; Biomarkers; Creatine; Creatinine; Electrophoresis, Capillary; Humans; Hypoxanthine; p-Aminohippuric Acid; Solid Phase Extraction; Uric Acid; Xanthine | 2007 |
Oxidative kidney damage in preterm newborns during perinatal period.
Topics: Acetylglucosaminidase; Alpha-Globulins; Female; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kidney Diseases; Male; Oxidative Stress; Xanthine | 2007 |
The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Enzyme Activators; Evoked Potentials, Somatosensory; Free Radicals; Hypoxanthine; Hypoxia-Ischemia, Brain; Infusions, Intravenous; Male; Neurofilament Proteins; Rabbits; Random Allocation; Recovery of Function; Xanthine; Xanthine Oxidase | 2007 |
Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function.
Topics: Female; Guanosine; Humans; Hypoxanthine; Inosine; Kidney Transplantation; Male; Middle Aged; Nucleosides; Predictive Value of Tests; Renal Veins; Reperfusion; Uric Acid; Uridine; Xanthine | 2007 |
[Recurrent urinary lithiasis revealing hereditary xanthinuria].
Topics: Adult; Calculi; Calorimetry; Child, Preschool; Chromatography, Gas; Female; Humans; Hypoxanthine; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Recurrence; Sodium Bicarbonate; Spectrophotometry, Infrared; Time Factors; Urolithiasis; Xanthine | 2007 |
Cell adhesion and integrin expression are modulated by oxidative stress in EA.hy 926 cells.
Topics: Apoptosis; Cell Adhesion; Cell Line; Endothelium, Vascular; Flow Cytometry; Humans; Hypoxanthine; Integrins; Kinetics; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Compounds; tert-Butylhydroperoxide; Xanthine | 2007 |
Interaction of the family-B DNA polymerase from the archaeon Pyrococcus furiosus with deaminated bases.
Topics: Archaeal Proteins; Deamination; DNA; DNA-Directed DNA Polymerase; Hypoxanthine; Molecular Structure; Polymerase Chain Reaction; Protein Binding; Pyrococcus furiosus; Uracil; Xanthine | 2007 |
Posttranslational ruling of xanthine oxidase activity in bovine milk by its substrates.
Topics: Animals; Bacterial Infections; Cattle; Escherichia coli; Female; Hydrogen Peroxide; Hypoxanthine; Mammary Glands, Animal; Milk; Oxytocics; Oxytocin; Protein Processing, Post-Translational; Staphylococcus aureus; Substrate Specificity; Time Factors; Uric Acid; Xanthine; Xanthine Oxidase | 2007 |
A study of the metabolism of dietary hypoxanthine and xanthine in the rat.
Topics: Animals; Diet; Hypoxanthine; Rats; Xanthine; Xanthines | 1949 |
Plasmodium-induced inflammation by uric acid.
Topics: Animals; Culture Media, Conditioned; Dendritic Cells; Disease Models, Animal; Erythrocytes; Hypoxanthine; Inflammation; Mice; Mice, Inbred BALB C; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Schizonts; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine | 2008 |
Examination of performance of glassy carbon paste electrode modified with gold nanoparticle and xanthine oxidase for xanthine and hypoxanthine detection.
Topics: Biosensing Techniques; Carbon; Electrochemistry; Electrodes; Glass; Gold; Hydrogen-Ion Concentration; Hypoxanthine; Linear Models; Metal Nanoparticles; Microscopy, Electron, Scanning; Nanocomposites; Xanthine; Xanthine Oxidase | 2007 |
Biochemical and structural characterization of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Pyrococcus horikoshii.
Topics: Amino Acid Sequence; Archaeal Proteins; Chromatography, Gel; Circular Dichroism; Dimerization; Electrophoresis, Polyacrylamide Gel; Guanine; Guanosine Monophosphate; Hypoxanthine; Molecular Sequence Data; Pentosyltransferases; Pyrococcus horikoshii; Sequence Homology, Amino Acid; Xanthine | 2008 |
Therapeutic criteria in communicating childhood hydrocephalus.
Topics: Blood Flow Velocity; Body Size; Cerebrovascular Circulation; Head; Humans; Hydrocephalus; Hypoxanthine; Infant; Ultrasonography, Doppler, Transcranial; Uric Acid; Xanthine | 2008 |
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction.
Topics: Animals; Diaphragm; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Hypoxanthine; Lipid Peroxidation; Muscle Contraction; Muscle Weakness; Muscular Atrophy; Oxidative Stress; Oxypurinol; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid; Ventilator-Induced Lung Injury; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 2009 |
An ab initio study of substituent effects on the excited states of purine derivatives.
Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine | 2008 |
Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase.
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Eukaryotic Cells; Hypoxanthine; Mutation; Oxypurinol; Protein Folding; Protein Structure, Quaternary; Pterins; Rhodobacter capsulatus; Xanthine; Xanthine Dehydrogenase | 2009 |
Simultaneous electrochemical monitoring of metabolites related to the xanthine oxidase pathway using a grinded carbon electrode.
Topics: Allopurinol; Biosensing Techniques; Carbon; Electrochemical Techniques; Electrodes; Enzyme Inhibitors; Humans; Hypoxanthine; Oxypurinol; Purinones; Sensitivity and Specificity; Uric Acid; Xanthine; Xanthine Oxidase | 2009 |
Effects of allopurinol on uric acid concentrations, xanthine oxidoreductase activity and oxidative stress in broiler chickens.
Topics: Age Factors; Allantoin; Allopurinol; Animals; Blood Glucose; Body Weight; Chickens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hypoxanthine; Intestines; Liver; Male; Oxidative Stress; Pancreas; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 2010 |
Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.
Topics: Adipogenesis; Animals; Disease Models, Animal; Epithelial Cells; Female; Fibrosis; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Hypoxanthine; Kidney Tubules; Lipid Metabolism; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis, Interstitial; Oxidative Stress; Purines; Triglycerides; Xanthine; Xanthine Dehydrogenase | 2009 |
Idiopathic recurrent calcium urolithiasis (IRCU): variation of fasting urinary protein is a window to pathophysiology or simple consequence of renal stones in situ? A tripartite study in male patients providing insight into oxidative metabolism as possibl
Topics: Adult; Body Mass Index; Calcium Oxalate; Calcium Phosphates; Cross-Sectional Studies; Crystallization; Fasting; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Insulin; Kidney; Kidney Calculi; Male; Malondialdehyde; Microscopy, Electron, Scanning; Proteinuria; Recurrence; Retrospective Studies; Uric Acid; Urinalysis; Urolithiasis; Xanthine | 2009 |
Acceleration of purine degradation by periodontal diseases.
Topics: Adult; Aged; Cadaverine; Chronic Periodontitis; Female; Gingiva; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Glutathione; Host-Pathogen Interactions; Humans; Hypoxanthine; Male; Metabolome; Middle Aged; Oxidative Stress; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Pocket; Purines; Putrescine; Reactive Oxygen Species; Up-Regulation; Uric Acid; Xanthine | 2009 |
Evidence of overestimation of rate constants for the superoxide trapping by nitrones in aqueous media.
Topics: Cyclic N-Oxides; Hypoxanthine; Kinetics; Models, Molecular; Nitrogen Oxides; Pyrroles; Superoxides; Water; Xanthine; Xanthine Oxidase | 2005 |
Determination of residual cell culture media components by MEKC.
Topics: Chromatography, Micellar Electrokinetic Capillary; Culture Media; Folic Acid; Hydrogen-Ion Concentration; Hypoxanthine; Limit of Detection; Mycophenolic Acid; Niacin; Reproducibility of Results; Riboflavin; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Xanthine | 2009 |
Molybdenum cofactor deficiency in a Malaysian child.
Topics: Brain Diseases; Child; Coenzymes; Cysteine; Diagnosis, Differential; Humans; Hypoxanthine; Hypoxia; Ischemia; Malaysia; Male; Metalloproteins; Molybdenum Cofactors; Pteridines; Sulfites; Uric Acid; Xanthine | 2009 |
Influence on energy kinetics and histology of different preservation solutions seen during cold ischemia in the liver.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; Glutathione; Hypoxanthine; Insulin; Ischemia; Kinetics; Liver; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Reperfusion Injury; Reticulin; Uric Acid; Uridine; Xanthine | 2009 |
Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Topics: Allantoin; Animals; Biomarkers; Cardiovascular Agents; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypoxanthine; Inosine; Least-Squares Analysis; Male; Metabolomics; Myocardial Ischemia; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization; Tablets; Xanthine | 2010 |
[Comparation study on quality of different population of wild and breeding Whitmania pigra].
Topics: Animals; Breeding; Female; Hypoxanthine; Leeches; Male; Xanthine | 2010 |
Nucleotides and their degradation products during processing of dry-cured ham, measured by HPLC and an enzyme sensor.
Topics: Animals; Chlorides; Chromatography, High Pressure Liquid; Food Analysis; Food Handling; Hypoxanthine; Inosine; Meat; Nucleotides; Purines; Swine; Xanthine | 2011 |
Xanthine dehydrogenase electrocatalysis: autocatalysis and novel activity.
Topics: Allopurinol; Biocatalysis; Electrochemistry; Electrodes; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Hypoxanthine; Imines; NAD; Oxidation-Reduction; Rhodobacter capsulatus; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2011 |
Theoretical study of valance photoelectron spectra of hypoxanthine, xanthine, and caffeine using direct symmetry-adapted cluster/configuration interaction methodology.
Topics: Caffeine; Computer Simulation; Hypoxanthine; Models, Molecular; Models, Theoretical; Photochemistry; Quantum Theory; Xanthine | 2011 |
Possible biological markers of the time of processing of dry-cured ham.
Topics: Adenosine Monophosphate; Animals; Biomarkers; Creatine; Creatinine; Desiccation; Food Handling; Guanosine; Hypoxanthine; Inosine; Meat Products; Swine; Uridine; Xanthine | 2011 |
The tumor lysis syndrome.
Topics: Allopurinol; Drug Costs; Humans; Hypoxanthine; Kidney Diseases; Tumor Lysis Syndrome; Urate Oxidase; Xanthine | 2011 |
Simultaneous determination of uric acid, xanthine and hypoxanthine at poly(pyrocatechol violet)/functionalized multi-walled carbon nanotubes composite film modified electrode.
Topics: Benzenesulfonates; Electrodes; Humans; Hypoxanthine; Nanotechnology; Nanotubes, Carbon; Polymers; Uric Acid; Xanthine | 2011 |
Training-induced adaptation in purine metabolism in high-level sprinters vs. triathletes.
Topics: Adaptation, Physiological; Adult; Athletes; Erythrocytes; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Male; Physical Endurance; Respiratory Function Tests; Running; Uric Acid; Xanthine; Young Adult | 2012 |
An amperometric biosensor for fish freshness detection from xanthine oxidase immobilized in polypyrrole-polyvinylsulphonate film.
Topics: Animals; Biocatalysis; Biosensing Techniques; Electrochemistry; Electrodes; Enzymes, Immobilized; Fishes; Food Analysis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypoxanthine; Methylene Blue; Polymers; Polyvinyls; Pyrroles; Reproducibility of Results; Sulfonic Acids; Temperature; Uric Acid; Xanthine; Xanthine Oxidase | 2012 |
Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA.
Topics: DNA; Hypoxanthine; Purine Nucleotides; RNA; Xanthine | 2012 |
Simultaneous electrochemical determination of uric acid, xanthine and hypoxanthine based on poly(L-arginine)/graphene composite film modified electrode.
Topics: Electrochemistry; Electrodes; Graphite; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Linear Models; Oxidation-Reduction; Oxides; Peptides; Reproducibility of Results; Time Factors; Uric Acid; Xanthine | 2012 |
X-ray spectroscopy of heterocyclic biochemicals: xanthine, hypoxanthine, and caffeine.
Topics: Caffeine; Carbon; Gases; Hypoxanthine; Models, Chemical; Molecular Structure; Nitrogen; Oxygen; Quantum Theory; Spectrometry, X-Ray Emission; X-Ray Absorption Spectroscopy; Xanthine | 2012 |
Amperometric detection of hypoxanthine and xanthine by enzymatic amplification using a gold nanoparticles-carbon nanohorn hybrid as the carrier.
Topics: Biosensing Techniques; Carbon; Electrochemical Techniques; Gold; Hypoxanthine; Metal Nanoparticles; Microscopy, Electron, Scanning; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Xanthine | 2012 |
A case of hereditary xanthinuria type 1 accompanied by bilateral renal calculi.
Topics: Aged; Amino Acid Sequence; Base Sequence; Codon, Nonsense; DNA Mutational Analysis; Female; Humans; Hypoxanthine; Kidney Calculi; Metabolism, Inborn Errors; Sequence Deletion; Xanthine; Xanthine Dehydrogenase | 2012 |
Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout.
Topics: Animals; Chromatography, High Pressure Liquid; Gout; Guanosine; Humans; Hypoxanthine; Male; Mice; Ribonucleosides; Tryptophan; Uric Acid; Xanthine; Xanthines | 2012 |
Applications of Tandem Mass Spectrometry (LC-MSMS) in estimating the post-mortem interval using the biochemistry of the vitreous humour.
Topics: Chromatography, Liquid; Forensic Pathology; Guanine; Humans; Hypoxanthine; Limit of Detection; Postmortem Changes; Tandem Mass Spectrometry; Uric Acid; Vitreous Body; Xanthine | 2012 |
Purine metabolites in fibromyalgia syndrome.
Topics: Adenosine; Adult; Aged; Case-Control Studies; Female; Fibromyalgia; Humans; Hypoxanthine; Inosine; Middle Aged; Purines; Reference Values; Surveys and Questionnaires; Xanthine | 2013 |
Low-potential amperometric enzyme biosensor for xanthine and hypoxanthine.
Topics: Biosensing Techniques; Catalysis; Electrochemistry; Electrodes; Graphite; Hydrogen-Ion Concentration; Hypoxanthine; Oxidation-Reduction; Rhodobacter capsulatus; Signal-To-Noise Ratio; Xanthine; Xanthine Dehydrogenase | 2012 |
Exercise-induced oxidative stress in elderly subjects: the effect of red orange supplementation on the biochemical and cellular response to a single bout of intense physical activity.
Topics: Administration, Oral; Aged; Antioxidants; Ascorbic Acid; Beverages; Biomarkers; Citrus sinensis; Dietary Supplements; DNA Damage; Exercise; Female; Hemolysis; Homeostasis; Humans; Hypoxanthine; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Physical Exertion; Plant Extracts; Xanthine | 2013 |
Xanthine urolithiasis causing bilateral ureteral obstruction in a 10-month-old cat.
Topics: Animals; Cat Diseases; Cats; Female; Hypoxanthine; Ureteral Obstruction; Urolithiasis; Xanthine | 2013 |
UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant.
Topics: Anticoagulants; Artifacts; Chromatography, High Pressure Liquid; Citric Acid; Edetic Acid; Heparin; Humans; Hypoxanthine; Metabolomics; Multivariate Analysis; Plasma; Principal Component Analysis; Serum; Spectrometry, Mass, Electrospray Ionization; Xanthine | 2013 |
Simultaneous determination of uric acid, xanthine, hypoxanthine and caffeine in human blood serum and urine samples using electrochemically reduced graphene oxide modified electrode.
Topics: Blood Chemical Analysis; Caffeine; Catalysis; Electrochemistry; Electrodes; Graphite; Humans; Hypoxanthine; Oxidation-Reduction; Oxides; Purines; Spectrum Analysis, Raman; Time Factors; Uric Acid; Urinalysis; Xanthine | 2013 |
Hypoxanthine as a predictor of performance in highly trained athletes.
Topics: Adolescent; Adult; Athletes; Athletic Performance; Exercise Test; Humans; Hypoxanthine; Lactic Acid; Male; Oxygen Consumption; Physical Endurance; Regression Analysis; Running; Uric Acid; Xanthine; Young Adult | 2013 |
Arxula adeninivorans xanthine oxidoreductase and its application in the production of food with low purine content.
Topics: Food Additives; Hypoxanthine; Purines; Saccharomycetales; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2013 |
Urine concentrations of xanthine, hypoxanthine and uric acid in UK Cavalier King Charles spaniels.
Topics: Animals; Breeding; Chromatography, High Pressure Liquid; Creatinine; Dogs; Female; Hypoxanthine; Male; Species Specificity; United Kingdom; Uric Acid; Urolithiasis; Xanthine | 2013 |
Low-potential amperometric determination of purine derivatives through surface oxide regeneration method.
Topics: Adenine; Copper; Electrochemical Techniques; Guanine; Hypoxanthine; Limit of Detection; Oxidation-Reduction; Purines; Uric Acid; Xanthine | 2013 |
Specificities and pH profiles of adenine and hypoxanthine-guanine-xanthine phosphoribosyltransferases (nucleotide synthases) of the thermoacidophile archaeon Sulfolobus solfataricus.
Topics: Adenine; Amino Acid Sequence; Archaeal Proteins; Base Sequence; Guanine; Hydrogen-Ion Concentration; Hypoxanthine; Molecular Sequence Data; Pentosyltransferases; Substrate Specificity; Sulfolobus solfataricus; Xanthine | 2014 |
Analysis of purine metabolites in maternal serum for evaluating the risk of gestosis.
Topics: Adult; Biomarkers; Chromatography, Reverse-Phase; Female; Gestational Age; Humans; Hypoxanthine; Infant, Newborn; Infant, Premature; Pre-Eclampsia; Pregnancy; Risk; Uric Acid; Xanthine | 2013 |
Specificity and catalytic mechanism in family 5 uracil DNA glycosylase.
Topics: Amino Acid Sequence; Catalysis; DNA Repair; Hypoxanthine; Kinetics; Models, Molecular; Molecular Sequence Data; Sequence Alignment; Substrate Specificity; Thermus thermophilus; Uracil; Uracil-DNA Glycosidase; Xanthine | 2014 |
An insight into prototropism and supramolecular motifs in solid-state structures of allopurinol, hypoxanthine, xanthine, and uric acid. A ¹H-¹⁴N NQDR spectroscopy, hybrid DFT/QTAIM, and Hirshfeld surface-based study.
Topics: Allopurinol; Hydrogen; Hydrogen Bonding; Hypoxanthine; Magnetic Resonance Spectroscopy; Models, Molecular; Nitrogen; Quantum Theory; Uric Acid; Xanthine; Xanthine Oxidase | 2014 |
[Determination of four kinds of purines in deer fetus soft capsule by HPLC].
Topics: Adenine; Animals; Capsules; Chromatography, High Pressure Liquid; Deer; Fetus; Guanine; Hypoxanthine; Materia Medica; Purines; Quality Control; Reproducibility of Results; Xanthine | 2014 |
A new voltammetric sensor for sensitive and selective determination of xanthine based on DNA and polyaniline composite Langmuir-Blodgett film.
Topics: Adsorption; Aniline Compounds; Biosensing Techniques; Calibration; Carbon; DNA; Electrochemistry; Electrodes; Glass; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Limit of Detection; Microscopy, Electron, Scanning; Phosphates; Purines; Reproducibility of Results; Uric Acid; Xanthine | 2014 |
Hyperuricemia and gout due to deficiency of hypoxanthine-guanine phosphoribosyltransferase in female carriers: New insight to differential diagnosis.
Topics: Adult; Child; Diagnosis, Differential; Female; Gout; Heterozygote; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Male; Mutation; Pedigree; Xanthine | 2015 |
Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study.
Topics: Aged; Allopurinol; Antineoplastic Agents; Creatinine; Enzyme Inhibitors; Febuxostat; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Humans; Hypoxanthine; Male; Middle Aged; Pilot Projects; Prospective Studies; Thiazoles; Tumor Lysis Syndrome; Uric Acid; Xanthine; Xanthine Oxidase | 2014 |
Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy.
Topics: Adult; Female; Humans; Hydrogen Peroxide; Hypoxanthine; Immunity, Innate; Infant, Newborn; Male; Microbiota; Milk, Human; Mouth; Nucleotides; Saliva; Thiocyanates; Xanthine; Xanthine Oxidase | 2015 |
Reduction of urinary uric acid excretion in patients with proteinuria.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hydrophobic and Hydrophilic Interactions; Hypoxanthine; Limit of Detection; Linear Models; Male; Middle Aged; Proteinuria; Reproducibility of Results; Uric Acid; Xanthine; Young Adult | 2015 |
Hypercrosslinked strong cation-exchange polymers for selective extraction of serum purine metabolites associated with gout.
Topics: Cation Exchange Resins; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Gout; Humans; Hypoxanthine; Inosine; Microscopy, Electron, Scanning; Polymers; Purines; Reproducibility of Results; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Uric Acid; Xanthine | 2016 |
[Xanthinuria type 1 in a woman with arthralgias: a combined clinical and molecular genetic investigation].
Topics: Arthralgia; Female; Humans; Hypoxanthine; Metabolism, Inborn Errors; Middle Aged; Xanthine; Xanthine Dehydrogenase | 2016 |
Label-Free Surface Enhanced Raman Scattering Approach for High-Throughput Screening of Biocatalysts.
Topics: Biocatalysis; High-Throughput Screening Assays; Hypoxanthine; Molecular Structure; Spectrum Analysis, Raman; Surface Properties; Uric Acid; Xanthine; Xanthine Oxidase | 2016 |
Mouse model for molybdenum cofactor deficiency type B recapitulates the phenotype observed in molybdenum cofactor deficient patients.
Topics: Animals; Apoptosis; Carbon-Carbon Lyases; Coenzymes; Cysteine; Disease Models, Animal; Gene Expression; Humans; Hypoxanthine; Metal Metabolism, Inborn Errors; Metalloproteins; Mice; Mice, Knockout; Molybdenum Cofactors; Mutation; Nuclear Proteins; Phenotype; Pteridines; Xanthine | 2016 |
An ultrasensitive electrochemical sensor for simultaneous determination of xanthine, hypoxanthine and uric acid based on Co doped CeO2 nanoparticles.
Topics: Carbon; Cerium; Copper; Electrochemical Techniques; Electrodes; Humans; Hypoxanthine; Limit of Detection; Magnetics; Metal Nanoparticles; Microwaves; Oxidation-Reduction; Reproducibility of Results; Spectrometry, X-Ray Emission; Spectrum Analysis, Raman; Uric Acid; X-Ray Diffraction; Xanthine | 2016 |
The Mechanism of False in Vitro Elevation of Uric Acid Level in Mouse Blood.
Topics: Animals; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Male; Mice, Inbred C57BL; Mice, Knockout; Urate Oxidase; Uric Acid; Xanthine | 2016 |
Increased oxidative stress alters nucleosides metabolite levels in sickle cell anemia.
Topics: Adult; Anemia, Sickle Cell; Antioxidants; Catalase; Female; Glutathione; Humans; Hypoxanthine; Lipid Peroxidation; Male; Middle Aged; Nucleosides; Oxidation-Reduction; Oxidative Stress; Peroxidase; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Uric Acid; Xanthine; Young Adult | 2017 |
Associations of plasma uric acid and purine metabolites with blood pressure in children: the KOALA Birth Cohort Study.
Topics: Blood Pressure; Child; Cohort Studies; Cross-Sectional Studies; Diastole; Female; Humans; Hypertension; Hypoxanthine; Male; Purines; Systole; Uric Acid; Xanthine; Xanthine Oxidase | 2017 |
Global and targeted serum metabolic profiling of colorectal cancer progression.
Topics: Adenoma; Adult; Aged; Caffeine; Case-Control Studies; Chromatography, Liquid; Colonic Polyps; Colorectal Neoplasms; Disease Progression; Female; Humans; Hypoxanthine; Intestinal Polyps; Logistic Models; Male; Mannose; Metabolomics; Middle Aged; Multivariate Analysis; Tandem Mass Spectrometry; Urea; Xanthine | 2017 |
Total glycosides of Paeony shows Neuroprotective effects against Semen Strychni-induced neurotoxicity by recovering secretion of hormones and improving brain energy metabolism.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Drugs, Chinese Herbal; Energy Metabolism; Estradiol; Estriol; Estrone; Growth Hormone; Hypoxanthine; Male; Neuroprotective Agents; Paeonia; Plant Extracts; Rats; Rats, Sprague-Dawley; Strychnos nux-vomica; Xanthine | 2017 |
L. donovani XPRT: Molecular characterization and evaluation of inhibitors.
Topics: Amino Acid Sequence; Biocatalysis; Enzyme Inhibitors; Guanine; Humans; Hypoxanthine; Kinetics; Leishmania donovani; Molecular Docking Simulation; Molecular Dynamics Simulation; Pentosyltransferases; Phylogeny; Protozoan Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Xanthine | 2018 |
Simultaneous quantification by HPLC of purines in umami soup stock and evaluation of their effects on extracellular and intracellular purine metabolism.
Topics: Animals; Chromatography, High Pressure Liquid; Food; Food Ingredients; Guanosine; Hep G2 Cells; Humans; Hypoxanthine; Inosine; Purines; Uric Acid; Xanthine | 2018 |
Protective effect of propofol on ischemia-reperfusion injury detected by HPLC-MS/MS targeted metabolic profiling.
Topics: Anesthetics, Intravenous; Cell Hypoxia; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Human Umbilical Vein Endothelial Cells; Humans; Hypnotics and Sedatives; Hypoxanthine; Metabolomics; Propofol; Reactive Oxygen Species; Reperfusion Injury; Tandem Mass Spectrometry; Xanthine | 2018 |
Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adipose Tissue, White; Adolescent; Adult; Animals; Cells, Cultured; Humans; Hypoxanthine; Hypoxia; Male; Mice; Mice, Inbred C57BL; Uric Acid; Xanthine; Xanthine Dehydrogenase; Young Adult | 2018 |
Uropathogenic Escherichia coli preferentially utilize metabolites in urine for nucleotide biosynthesis through salvage pathways.
Topics: Animals; Escherichia coli Infections; Escherichia coli Proteins; Female; Humans; Hypoxanthine; Kidney; Mice; Mice, Inbred CBA; Mutagenesis; Nucleotides; Uracil; Urinary Bladder; Urinary Tract; Urinary Tract Infections; Uropathogenic Escherichia coli; Xanthine | 2018 |
A non-enzymatic voltammetric xanthine sensor based on the use of platinum nanoparticles loaded with a metal-organic framework of type MIL-101(Cr). Application to simultaneous detection of dopamine, uric acid, xanthine and hypoxanthine.
Topics: Biosensing Techniques; Dopamine; Electrochemical Techniques; Humans; Hypoxanthine; Metal Nanoparticles; Metal-Organic Frameworks; Platinum; Uric Acid; Xanthine | 2018 |
Simultaneous detection of ATP metabolites in human plasma and urine based on palladium nanoparticle and poly(bromocresol green) composite sensor.
Topics: Adenosine Triphosphate; Biosensing Techniques; Humans; Hypoxanthine; Inosine; Metabolome; Metal Nanoparticles; Nanotubes, Carbon; Palladium; Uric Acid; Xanthine | 2019 |
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
Topics: Allopurinol; Cells, Cultured; Enzyme Inhibitors; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Purine-Nucleoside Phosphorylase; Purines; Pyrimidinones; Pyrroles; Reproducibility of Results; Uric Acid; Xanthine | 2019 |
Study on the diagnosis of gout with xanthine and hypoxanthine.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Gout; Humans; Hyperuricemia; Hypoxanthine; Limit of Detection; Male; Reproducibility of Results; Uric Acid; Xanthine | 2019 |
Changes in Blood Concentration of Adenosine Triphosphate Metabolism Biomarkers During Incremental Exercise in Highly Trained Athletes of Different Sport Specializations.
Topics: Absorptiometry, Photon; Adaptation, Physiological; Adenosine Triphosphate; Adolescent; Adult; Ammonia; Biomarkers; Exercise Test; Humans; Hypoxanthine; Lactic Acid; Muscle, Skeletal; Organ Size; Physical Fitness; Running; Uric Acid; Xanthine; Young Adult | 2019 |
Purine metabolism in sprint- vs endurance-trained athletes aged 20‒90 years.
Topics: Adult; Aged; Aged, 80 and over; Athletes; Erythrocytes; Exercise Test; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Male; Middle Aged; Muscle, Skeletal; Physical Conditioning, Animal; Physical Endurance; Purines; Running; Xanthine | 2019 |
Change in Lactate, Ammonia, and Hypoxanthine Concentrations in a 1-Year Training Cycle in Highly Trained Athletes: Applying Biomarkers as Tools to Assess Training Status.
Topics: Adult; Ammonia; Athletes; Biomarkers; Exercise Test; Humans; Hypoxanthine; Lactic Acid; Male; Physical Conditioning, Human; Physical Fitness; Uric Acid; Xanthine; Young Adult | 2020 |
Purine metabolites can indicate diabetes progression.
Topics: Animals; Diabetes Mellitus; Hypoxanthine; Purines; Rats; Uric Acid; Xanthine | 2022 |
Triethylamine-controlled Cu-BTC frameworks for electrochemical sensing fish freshness.
Topics: Animals; Copper; Electrochemical Techniques; Ethylamines; Fish Products; Fishes; Food Analysis; Hypoxanthine; Metal-Organic Frameworks; Particle Size; Surface Properties; Tricarboxylic Acids; Xanthine | 2019 |
Nucleobase synthesis in interstellar ices.
Topics: Adenine; Ammonia; Carbon Monoxide; Cytosine; Evolution, Chemical; Extraterrestrial Environment; Hypoxanthine; Ice; Methanol; Molecular Structure; Photochemical Processes; Thymine; Ultraviolet Rays; Uracil; Water; Xanthine | 2019 |
In-situ reduction of Ag
Topics: Biosensing Techniques; Carboxymethylcellulose Sodium; Electrochemical Techniques; Humans; Hypoxanthine; Limit of Detection; Metal Nanoparticles; Nanocomposites; Nanotubes, Carbon; Oxygen; Silver; Uric Acid; Water; Xanthine | 2019 |
Differential regulation of hypoxanthine and xanthine by obesity in a general population.
Topics: Adipose Tissue; Aged; Alanine Transaminase; Biomarkers; Body Mass Index; Enzyme Inhibitors; Female; Humans; Hyperuricemia; Hypoxanthine; Japan; Liver; Male; Middle Aged; Obesity; Regression Analysis; Signal Transduction; Triglycerides; Xanthine; Xanthine Dehydrogenase | 2020 |
Specificity profile of NAT/NCS2 purine transporters in Sinorhizobium (Ensifer) meliloti.
Topics: Adenine; Biological Transport, Active; Escherichia coli K12; Guanine; Hypoxanthine; Membrane Transport Proteins; Plant Root Nodulation; Rhizosphere; Root Nodules, Plant; Sinorhizobium meliloti; Symporters; Uric Acid; Xanthine | 2020 |
Facile synthesis of large area pebble-like β-NaFeO
Topics: Calcium Compounds; Dopamine; Humans; Hypoxanthine; Iron Compounds; Oxides; Titanium; Uric Acid; Xanthine | 2020 |
A simple electrochemical approach to fabricate functionalized MWCNT-nanogold decorated PEDOT nanohybrid for simultaneous quantification of uric acid, xanthine and hypoxanthine.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Electrochemical Techniques; Gold; Hypoxanthine; Metal Nanoparticles; Molecular Structure; Nanotubes, Carbon; Particle Size; Polymers; Surface Properties; Uric Acid; Xanthine | 2020 |
Identification of the molecular mechanism and diagnostic biomarkers in the thoracic ossification of the ligamentum flavum using metabolomics and transcriptomics.
Topics: Adult; Biomarkers; Chromatography, Liquid; Cohort Studies; Female; Humans; Hypoxanthine; Ligamentum Flavum; Male; Metabolomics; Middle Aged; Ossification, Heterotopic; Purines; ROC Curve; Tandem Mass Spectrometry; Thoracic Vertebrae; Transcriptome; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2020 |
Exploring serum metabolic markers for the discrimination of ccRCC from renal angiomyolipoma by metabolomics.
Topics: Adult; Aged; Angiomyolipoma; Biomarkers, Tumor; Carcinoma, Renal Cell; Chromatography, High Pressure Liquid; Creatinine; Diagnosis, Differential; Female; Humans; Hypoxanthine; Kidney Neoplasms; Male; Metabolomics; Middle Aged; Multivariate Analysis; Proton Magnetic Resonance Spectroscopy; Uric Acid; Xanthine | 2020 |
Effect of allicin and its mechanism of action in purine removal in turbot.
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Cooking; Disulfides; Flatfishes; Food Handling; Gout; Humans; Hypoxanthine; Molecular Docking Simulation; Purines; Seafood; Sulfinic Acids; Xanthine | 2020 |
Fabrication of low-cost sustainable electrocatalyst: a diagnostic tool for multifunctional disorders in human fluids.
Topics: Ascorbic Acid; Biosensing Techniques; Caffeine; Carbon; Catalysis; Electrochemical Techniques; Electrodes; Female; Humans; Hypoxanthine; Male; Uric Acid; Xanthine | 2020 |
Improved ultra-high performance liquid chromatographic method for simultaneous determination of five gout-related metabolites in human serum.
Topics: Chromatography, High Pressure Liquid; Creatinine; Gout; Humans; Hypoxanthine; Inosine; Uric Acid; Xanthine | 2021 |
Elevated blood purine levels as a biomarker of seizures and epilepsy.
Topics: Adenosine; Adult; Animals; Biomarkers; Case-Control Studies; Epilepsy; Humans; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Point-of-Care Testing; Purines; Seizures; Severity of Illness Index; Status Epilepticus; Xanthine; Young Adult | 2021 |
Development of quantitative assay for simultaneous measurement of purine metabolites and creatinine in biobanked urine by liquid chromatography-tandem mass spectrometry.
Topics: Allantoin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Creatinine; Diabetes Mellitus, Type 2; Humans; Hypoxanthine; Purines; Tandem Mass Spectrometry; Uric Acid; Xanthine | 2022 |
Study on the levels of N-nitrosamine compounds and untargeted metabolomics in patients with colorectal cancer.
Topics: Chromatography, Liquid; Colorectal Neoplasms; Female; Humans; Hypoxanthine; Male; Metabolomics; Nitrosamines; Tandem Mass Spectrometry; Xanthine | 2022 |
Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites.
Topics: Animals; Guanine; Hypoxanthine; Purines; Xanthine | 2022 |
Spectroscopic investigation of faeces with surface-enhanced Raman scattering: a case study with coeliac patients on gluten-free diet.
Topics: Bacteria; Diet, Gluten-Free; Feces; Humans; Hypoxanthine; RNA, Ribosomal, 16S; Spectrum Analysis, Raman; Xanthine | 2022 |
Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.
Topics: Allopurinol; Clinical Studies as Topic; Humans; Hypoxanthine; Hypoxia; Hypoxia-Ischemia, Brain; Infant, Newborn; Mannitol; Oxypurinol; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2022 |
Brushite nanoparticles based electrochemical sensor for detection of uric acid, xanthine, hypoxanthine and caffeine.
Topics: Ascorbic Acid; Caffeine; Electrochemical Techniques; Electrodes; Humans; Hypoxanthine; Nanoparticles; Uric Acid; Xanthine | 2022 |
Intermediate products of purine metabolism in an experimental model of pancreatic necrosis.
Topics: Adenine; Animals; Guanine; Hypoxanthine; Models, Theoretical; Pancreatitis, Acute Necrotizing; Purines; Rabbits; Uric Acid; Xanthine | 2022 |
Simultaneous Determination of Xanthine and Hypoxanthine Using Polyglycine/rGO-Modified Glassy Carbon Electrode.
Topics: Carbon; Electrochemical Techniques; Electrodes; Graphite; Hypoxanthine; Oxides; Xanthine | 2023 |
Poly(para toluene sulphonic acid) and gold nanoparticles modified glassy carbon electrode for simultaneous voltammetric sensing of xanthine and hypoxanthine.
Topics: Carbon; Electrodes; Gold; Hypoxanthine; Metal Nanoparticles; Xanthine | 2023 |