Page last updated: 2024-08-18

xanthenes and ucb 35625

xanthenes has been researched along with ucb 35625 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Clapham, PR; Jorritsma, A; Pease, JE; Peck, MJ; Sabroe, I; Simmons, G; Van Keulen, BJ; Williams, TJ1
da Fonseca, PC; de Mendonça, FL; Pease, JE; Phillips, RM; Saldanha, JW; Williams, TJ1
Amat, M; Beleta, J; Benjamim, CF; Godessart, N; Kunkel, SL; Prats, N; Terricabras, E; Williams, LM1
Allen, RA; da Fonseca, PC; Duchesnes, C; Pease, JE; Williams, TJ; Wise, EL1
Batke, B; Biswal, S; Gambhir, SS; Gibon, E; Goodman, SB; Rao, AJ; Smith, RL; Valladares, R; Yao, Z; Zwingenberger, S1
Flamand, N; Langlois, A; Larose, MC; Laviolette, M; Provost, V; Rola-Pleszczynski, M1
Baamonde, A; Hidalgo, A; Lastra, A; Meana, Á; Menéndez, L; Pevida, M1
Baamonde, A; Fernández-García, MT; González-Rodríguez, S; Hidalgo, A; Lastra, A; Llorián-Salvador, M; Menéndez, L1
Corbisier, J; Galés, C; Huszagh, A; Parmentier, M; Springael, JY1
Kreiner, G; Mika, J; Nalepa, I; Piotrowska, A; Rojewska, E; Zychowska, M1
Ciapała, K; Kwiatkowski, K; Makuch, W; Mika, J; Pawlik, K; Piotrowska, A; Popiolek-Barczyk, K1

Other Studies

11 other study(ies) available for xanthenes and ucb 35625

ArticleYear
A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.
    The Journal of biological chemistry, 2000, Aug-25, Volume: 275, Issue:34

    Topics: Animals; Chemokine CCL11; Chemokine CCL3; Chemokine CCL4; Chemokines, CC; Cytokines; Drug Interactions; Eosinophils; Flow Cytometry; HIV-1; Humans; Macrophage Inflammatory Proteins; Mice; Models, Chemical; Monocyte Chemoattractant Proteins; Receptors, CCR1; Receptors, CCR3; Receptors, Chemokine; Transfection; Xanthenes

2000
Site-directed mutagenesis of CC chemokine receptor 1 reveals the mechanism of action of UCB 35625, a small molecule chemokine receptor antagonist.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Cell Membrane; Cell Movement; Chemotaxis; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Inflammation; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, CCR1; Receptors, Chemokine; Sequence Homology, Amino Acid; Signal Transduction; Software; Stereoisomerism; Transfection; Xanthenes

2005
Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo.
    British journal of pharmacology, 2006, Volume: 149, Issue:6

    Topics: Animals; Arthritis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Receptors, CCR1; Receptors, Chemokine; Tumor Necrosis Factor-alpha; Xanthenes

2006
Small molecule receptor agonists and antagonists of CCR3 provide insight into mechanisms of chemokine receptor activation.
    The Journal of biological chemistry, 2007, Sep-21, Volume: 282, Issue:38

    Topics: Animals; Binding Sites; Cell Line, Tumor; Chemokine CCL11; Chemokines; Chemokines, CC; Down-Regulation; Eosinophils; Glutamic Acid; Mice; Models, Biological; Molecular Conformation; Receptors, CCR3; Receptors, Chemokine; Tyrosine; Up-Regulation; Xanthenes

2007
Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss.
    Biomaterials, 2012, Volume: 33, Issue:14

    Topics: Animals; Biocompatible Materials; Cell Differentiation; Cell Movement; Chemotaxis; Humans; Joint Prosthesis; Male; Materials Testing; Mesenchymal Stem Cells; Mice; Mice, Knockout; Mice, Nude; Osteolysis; Polyethylenes; Prosthesis Failure; Receptors, CCR1; Xanthenes

2012
CCL26/eotaxin-3 is more effective to induce the migration of eosinophils of asthmatics than CCL11/eotaxin-1 and CCL24/eotaxin-2.
    Journal of leukocyte biology, 2013, Volume: 94, Issue:2

    Topics: Antibodies, Monoclonal; Arachidonic Acids; Asthma; Benzamides; Cells, Cultured; Chemokine CCL11; Chemokine CCL24; Chemokine CCL26; Chemokines, CC; Chemotactic Factors; Chemotaxis, Leukocyte; Eosinophils; Humans; Interleukin-5; Naphthalenes; Phenylalanine; Receptors, CCR3; Recombinant Proteins; Time Factors; Xanthenes

2013
The chemokine CCL5 induces CCR1-mediated hyperalgesia in mice inoculated with NCTC 2472 tumoral cells.
    Neuroscience, 2014, Feb-14, Volume: 259

    Topics: Analysis of Variance; Animals; Bone Neoplasms; Cell Line, Tumor; Chemokine CCL5; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Gene Expression Regulation, Neoplastic; Hyperalgesia; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation; Pain Measurement; Pain Threshold; Peptide T; Receptors, CCR1; Xanthenes

2014
Involvement of CC Chemokine Receptor 1 and CCL3 in Acute and Chronic Inflammatory Pain in Mice.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:1

    Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Chemokine CCL3; Chemokine CCL5; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Neutrophils; Receptors, CCR1; RNA, Messenger; Spinal Cord; Xanthenes

2016
Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.
    The Journal of biological chemistry, 2017, Jan-13, Volume: 292, Issue:2

    Topics: Amino Acid Substitution; Animals; beta-Arrestin 2; Cell Movement; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Mutation, Missense; Protein Binding; Receptors, CCR2; Receptors, CCR5; Signal Transduction; Xanthenes

2017
Involvement of Macrophage Inflammatory Protein-1 Family Members in the Development of Diabetic Neuropathy and Their Contribution to Effectiveness of Morphine.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Analgesics, Opioid; Animals; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Chemokines, CC; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Humans; Macrophage Inflammatory Proteins; Macrophages; Mice; Morphine Derivatives; Neuralgia; Neurons; Receptors, CCR1; Xanthenes

2018
The blockade of CC chemokine receptor type 1 influences the level of nociceptive factors and enhances opioid analgesic potency in a rat model of neuropathic pain.
    Immunology, 2020, Volume: 159, Issue:4

    Topics: Analgesics; Animals; Buprenorphine; Calcium-Binding Proteins; Chemokine CCL2; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Interleukin-18; Interleukin-1beta; Interleukin-6; Male; Microfilament Proteins; Morphine; Neuralgia; Nociception; Peroxidase; Protein Isoforms; Rats; Rats, Wistar; Receptors, CCR1; Sciatic Nerve; Signal Transduction; Xanthenes

2020