Page last updated: 2024-08-18

xanthenes and norathyriol

xanthenes has been researched along with norathyriol in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (34.78)18.2507
2000's4 (17.39)29.6817
2010's10 (43.48)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Ko, FN; Lin, CN; Liou, SS; Teng, CM1
Huang, TF; Ko, FN; Lin, CN; Liou, SS; Teng, CM1
Lin, CN; Raung, SL; Teng, CM; Wang, JP1
Ho, TF; Lin, CN; Teng, CM; Wang, JP1
Cheng, YW; Kang, JJ; Ko, FN; Kuo, ML; Lin, CN; Teng, CM1
Hsu, MF; Lin, CN; Raung, SL; Tsao, LT; Wang, JP1
Lin, CN; Raung, SL; Tsao, LT; Wang, JP1
Lee, HZ; Lin, CN; Lin, WC; Wu, CH; Yeh, FT1
Hsu, MF; Lin, CN; Lu, MC; Wang, JP1
Akao, T; Hattori, M; Kakiuchi, N; Li, Y; Nakamura, N; Sanugul, K1
Akao, T; Hattori, M; Nakamura, N; Sanugul, K1
Gidley, MJ; Lin, CN; Monteith, GR; Roberts-Thomson, SJ; Shaw, PN; Wilkinson, AS1
Huang, C; Jian, L; Li, Z; Liu, H; Sun, Z; Tang, Y; Wang, K; Wu, B1
Bode, AM; Carper, A; Dong, Z; Kim, MO; Kurinov, I; Langfald, A; Li, J; Malakhova, M; Mottamal, M; Oi, N; Reddy, K; Sosa, CP; Zhou, K; Zhu, F1
Li, L; Li, Y; Lin, H; Liu, J; Liu, X; Niu, Y; Wang, F; Yan, J1
Ding, H; Hou, D; Jiang, X; Li, J; Peng, W; Xu, C; Zen, K; Zhang, CY; Zhang, Y1
Dietzgen, RG; Gidley, MJ; Lin, CN; Monteith, GR; Pierson, JT; Roberts-Thomson, SJ; Shaw, PN; Taing, MW; Wilkinson, AS1
Feng, GH; Gao, LH; Li, L; Liu, HY; Liu, J; Liu, X; Niu, Y1
Gao, Y; Guo, X; Hu, P; Huang, C; Li, Z; Lian, S; Ma, Y; Tian, X; Xu, Z1
Chen, S; Cheng, M; Guo, X; Hu, P; Huang, C; Liu, H; Shi, H; Shi, Z; Tian, X; Xu, Z1
Tian, J; Wang, XS; Wu, S; Xia, J; Xue, W1
Gao, L; Li, F; Li, L; Li, N; Lin, H; Niu, Y; Tu, C; Xu, A; Yuan, L1
Goto, F; Higuchi, A; Hikage, T; Morgan, E; Nemoto, K; Nishihara, M; Nishizaki, Y; Sasaki, N; Sugimoto, N; Tasaki, K; Watanabe, A1

Other Studies

23 other study(ies) available for xanthenes and norathyriol

ArticleYear
Gamma-pyrone compounds. II: Synthesis and antiplatelet effects of tetraoxygenated xanthones.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:11

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Cells, Cultured; Collagen; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Structure-Activity Relationship; Xanthenes

1992
Vasorelaxation of rat thoracic aorta caused by norathyriol isolated from Gentianaceae.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium Radioisotopes; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Inosine Monophosphate; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Plants, Medicinal; Potassium; Rats; Rats, Inbred Strains; Xanthenes

1991
Inhibitory effect of norathyriol, a xanthone from Tripterospermum lanceolatum, on cutaneous plasma extravasation.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Adrenalectomy; Animals; Capillary Permeability; Cytoplasmic Granules; Edema; Electric Stimulation; Glucuronidase; Histamine Release; In Vitro Techniques; Inflammation; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Permeability; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Skin Absorption; Xanthenes

1994
Effect of norathyriol, isolated from Tripterospermum lanceolatum, on A23187-induced pleurisy and analgesia in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analgesia; Animals; Calcimycin; Dinoprostone; Female; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Mice; Neutrophils; Pleurisy; Radioimmunoassay; Xanthenes

1994
Induction of calcium release from sarcoplasmic reticulum of skeletal muscle by xanthone and norathyriol.
    British journal of pharmacology, 1996, Volume: 118, Issue:7

    Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Diaphragm; Female; In Vitro Techniques; Magnesium; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Phosphodiesterase Inhibitors; Potassium Chloride; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum; Xanthenes; Xanthones

1996
Examination of the inhibitory effect of norathyriol in formylmethionyl-leucyl-phenylalanine-induced respiratory burst in rat neutrophils.
    Free radical biology & medicine, 1997, Volume: 23, Issue:7

    Topics: Animals; Colforsin; Free Radical Scavengers; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Rats; Respiratory Burst; Xanthenes

1997
Evidence for the involvement of protein kinase C inhibition by norathyriol in the reduction of phorbol ester-induced neutrophil superoxide anion generation and aggregation.
    European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1

    Topics: Animals; Cell Aggregation; Cyclic AMP-Dependent Protein Kinases; Neutrophils; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Trypsin; Xanthenes

1997
Decreased protein kinase C activation mediates inhibitory effect of norathyriol on serotonin-mediated endothelial permeability.
    European journal of pharmacology, 1998, Jul-24, Volume: 353, Issue:2-3

    Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Protein Kinase C; Rats; Serotonin; Serotonin Antagonists; Staurosporine; Tetradecanoylphorbol Acetate; Xanthenes

1998
Inhibition of the arachidonic acid cascade by norathyriol via blockade of cyclooxygenase and lipoxygenase activity in neutrophils.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:5

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Cyclooxygenase Inhibitors; Lipoxygenase; Mast Cells; Mice; Neutrophils; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Xanthenes

2004
Isolation of a human intestinal bacterium that transforms mangiferin to norathyriol and inducibility of the enzyme that cleaves a C-glucosyl bond.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:9

    Topics: Antiviral Agents; Bacteria; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Enzyme Induction; Glucosidases; Intestines; RNA, Bacterial; RNA, Ribosomal, 16S; Xanthenes; Xanthones

2005
Two proteins, Mn2+, and low molecular cofactor are required for C-glucosyl-cleavage of mangiferin.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:11

    Topics: Anaerobiosis; Bacteroides; Cell-Free System; Chlorides; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Clostridium; Enzymes; Glucose; Hydrolysis; Manganese; Manganese Compounds; Molecular Weight; Xanthenes; Xanthones

2005
Effects of the mango components mangiferin and quercetin and the putative mangiferin metabolite norathyriol on the transactivation of peroxisome proliferator-activated receptor isoforms.
    Journal of agricultural and food chemistry, 2008, May-14, Volume: 56, Issue:9

    Topics: Fruit; Humans; Mangifera; Peroxisome Proliferator-Activated Receptors; Protein Isoforms; Quercetin; Transcriptional Activation; Transfection; Xanthenes; Xanthones

2008
Structure elucidation of in vivo and in vitro metabolites of mangiferin.
    Journal of pharmaceutical and biomedical analysis, 2011, Jul-15, Volume: 55, Issue:5

    Topics: Administration, Oral; Animals; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, Liquid; Glycosylation; In Vitro Techniques; Male; Methylation; Models, Chemical; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Xanthenes; Xanthones

2011
Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases.
    Cancer research, 2012, Jan-01, Volume: 72, Issue:1

    Topics: Animals; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Female; Mice; Models, Molecular; Neoplasms, Radiation-Induced; Protein Kinase Inhibitors; Skin Neoplasms; Sunlight; Xanthenes

2012
Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase.
    Pharmaceutical biology, 2014, Volume: 52, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Glucose; Hypoglycemic Agents; Immunoblotting; Insulin; Insulin Resistance; Muscle Fibers, Skeletal; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rosiglitazone; Thiazolidinediones; Up-Regulation; Xanthenes; Xanthones

2014
Norathyriol reverses obesity- and high-fat-diet-induced insulin resistance in mice through inhibition of PTP1B.
    Diabetologia, 2014, Volume: 57, Issue:10

    Topics: Animals; Blotting, Western; Diet, High-Fat; Immunoprecipitation; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Xanthenes

2014
Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol.
    Food & function, 2015, Volume: 6, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Survival; Chlorocebus aethiops; COS Cells; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Estrogen Receptor beta; Female; Fruit; Genes, Reporter; Humans; Mangifera; MCF-7 Cells; Neoplasm Proteins; Phytoestrogens; Quercetin; Recombinant Proteins; Response Elements; Transcriptional Activation; Xanthenes; Xanthones

2015
Hypouricaemic action of mangiferin results from metabolite norathyriol via inhibiting xanthine oxidase activity.
    Pharmaceutical biology, 2016, Volume: 54, Issue:9

    Topics: Administration, Oral; Animals; Biomarkers; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Gout Suppressants; Hyperuricemia; Kinetics; Mice; Molecular Structure; Oxonic Acid; Structure-Activity Relationship; Uric Acid; Xanthenes; Xanthine Oxidase; Xanthones

2016
Pharmacokinetics of mangiferin and its metabolite-norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor.
    BioFactors (Oxford, England), 2016, Sep-10, Volume: 42, Issue:5

    Topics: Administration, Oral; Anemarrhena; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Enterobacteriaceae; Gastrointestinal Microbiome; Glucuronosyltransferase; Hypoglycemic Agents; Inactivation, Metabolic; Male; Rats, Wistar; Rhizome; Saponins; Steroids; Xanthenes; Xanthones

2016
Absorption, Metabolism, and Pharmacokinetics Profiles of Norathyriol, an Aglycone of Mangiferin, in Rats by HPLC-MS/MS.
    Journal of agricultural and food chemistry, 2018, Nov-21, Volume: 66, Issue:46

    Topics: Animals; Chromatography, High Pressure Liquid; Hepatocytes; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Xanthenes; Xanthones

2018
Discovery of potent PTP1B inhibitors via structure-based drug design, synthesis and in vitro bioassay of Norathyriol derivatives.
    Bioorganic chemistry, 2019, Volume: 86

    Topics: Biological Assay; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Xanthenes

2019
Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition.
    European journal of pharmacology, 2019, Jun-15, Volume: 853

    Topics: Animals; Enzyme Inhibitors; HEK293 Cells; Humans; Hyperuricemia; Kidney; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Uric Acid; Xanthenes; Xanthine Oxidase

2019
Identification and characterization of xanthone biosynthetic genes contributing to the vivid red coloration of red-flowered gentian.
    The Plant journal : for cell and molecular biology, 2021, Volume: 107, Issue:6

    Topics: Acyltransferases; Anthocyanins; Chromatography, High Pressure Liquid; Flowers; Gentiana; Glucosyltransferases; Molecular Structure; Pigmentation; Pigments, Biological; Plant Proteins; Sequence Analysis, RNA; Xanthenes; Xanthones

2021