xanthenes has been researched along with ly 379268 in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (51.61) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Cartmell, J; Monn, JA; Perry, KW; Salhoff, CR; Schoepp, DD | 1 |
| Cartmell, J; Monn, JA; Schoepp, DD | 1 |
| Arcella, A; Battaglia, G; Bruno, V; Calogero, A; D'Onofrio, M; Lombari, V; Ngomba, RT; Nicoletti, F; Ragona, G | 1 |
| Anderson, JJ; Baccei, CS; Bristow, LJ; Campbell, UC; Correa, LD; Lorrain, DS; Pinkerton, AB; Rodriguez, DE; Rowe, B; Schaffhauser, H; Varney, MA; Vernier, JM | 1 |
| Battaglia, G; Biagioni, F; Bruno, V; Busceti, CL; Fornai, F; Nicoletti, F; Paparelli, A; Pontarelli, F; Ruggieri, S | 1 |
| Hashimoto, K; Iyo, M; Koike, K; Koizumi, H; Komatsu, N; Kumakiri, C; Ohgake, S; Okamura, N; Shimizu, E | 1 |
| Campbell, IG; Darchia, N; Feinberg, I; Hsieh, KC; Schoepp, DD | 1 |
| Alexander, GM; Godwin, DW | 2 |
| Battaglia, G; Canudas, AM; Del Bianco, P; Matrisciano, F; Melchiorri, D; Molinaro, G; Ngomba, RT; Nicoletti, F; Panaccione, I; Riozzi, B; Scaccianoce, S; Tatarelli, R | 1 |
| Chi, H; Jang, JK; Kim, JH; Vezina, P | 1 |
| Battaglia, G; Beraudi, A; Biagioni, F; Bruno, V; Nicoletti, F; Poli, A; Rampello, L | 1 |
| Girardi, P; Giusti, P; Gruber, SH; Iacovelli, L; Mathé, AA; Matrisciano, F; Nicoletti, F; Panaccione, I; Tatarelli, R; Zusso, M | 1 |
| Arcella, A; Battaglia, G; Carpinelli, G; Ciceroni, C; De Maria, R; Giangaspero, F; Mastrantoni, E; Melchiorri, D; Mosillo, P; Nicoletti, F; Oliva, MA; Pallini, R; Ricci-Vitiani, L; Sale, P; Santoro, F | 1 |
| Busceti, CL; Chiechio, S; Copani, A; Drago, F; Gereau, RW; Morales, ME; Nicoletti, F; Zammataro, M | 1 |
| Battaglia, G; Bruno, V; Curto, M; Di Menna, L; Molinaro, G; Nicoletti, F; Pallottino, S; Riozzi, B; Traficante, A | 1 |
| Belluardo, N; Bonomo, A; Di Liberto, V; Frinchi, M; Mudò, G | 1 |
| Amitai, N; Markou, A | 1 |
| Battaglia, G; Britton, TC; Bruno, V; Cannella, M; Caraci, F; Copani, A; Drago, F; Giuffrida, ML; Heinz, BA; Merlo, S; Molinaro, G; Nicoletti, F; Nisenbaum, ES; Riozzi, B; Sortino, MA; Traficante, A; Wang, X | 1 |
| Rushlow, WJ; Sutton, LP | 1 |
| Conn, PJ; Johnson, KA; Niswender, CM; Xiang, Z | 1 |
| Dong, E; Sanford, LD; Wellman, LL; Yang, L | 1 |
| Raiteri, L; Raiteri, M; Romei, C | 1 |
| Gao, WJ; Li, F; Li, YC; Snyder, MA; Wang, H; Wang, MJ | 1 |
| Chaki, S; Hikichi, H; Kaku, A; Karasawa, J | 1 |
| Shu, H; Song, Y; Wang, B; Yang, H; Zhang, C; Zhou, K; Zhou, W | 1 |
| Kiritoshi, T; Neugebauer, V | 1 |
| Besheer, J; Fisher, KR; Frisbee, S; Jaramillo, AA; Randall, PA | 1 |
| Barker, JM; Chandler, LJ; Lench, DH | 1 |
| Mazzitelli, M; Neugebauer, V | 1 |
| Cao, AM; Fatemi, F; Margeat, E; Pin, JP; Quast, RB; Rondard, P | 1 |
31 other study(ies) available for xanthenes and ly 379268
| Article | Year |
|---|---|
The potent, selective mGlu2/3 receptor agonist LY379268 increases extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindole-3-acetic acid in the medial prefrontal cortex of the freely moving rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes | 2000 |
The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing.
Topics: Amino Acids; Amphetamine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereotyped Behavior; Xanthenes | 2000 |
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells.
Topics: Amino Acids; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cyclin D1; Cyclin D2; Cyclins; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Receptors, Metabotropic Glutamate; Thymidine; Tritium; Xanthenes | 2003 |
Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Analysis of Variance; Animals; Area Under Curve; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Hyperkinesis; In Vitro Techniques; Ketamine; Male; Microdialysis; Motor Activity; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Schizophrenia; Serotonin; Sulfur Isotopes; Time Factors; Trifluoroethanol; Xanthenes | 2003 |
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Receptors, AMPA; Xanthenes | 2003 |
Protective effect of LY379268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex.
Topics: Acetylcholine; Amino Acids; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Fluid; Female; HSP70 Heat-Shock Proteins; Immunohistochemistry; Microdialysis; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes | 2003 |
The metabotropic glutamate (mGLU)2/3 receptor antagonist LY341495 [2S-2-amino-2-(1S,2S-2-carboxycyclopropyl-1-yl)-3-(xanth-9-yl)propanoic acid] stimulates waking and fast electroencephalogram power and blocks the effects of the mGLU2/3 receptor agonist ly
Topics: Amino Acids; Animals; Arousal; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Darkness; Electroencephalography; Excitatory Amino Acid Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sleep; Sleep Stages; Wakefulness; Xanthenes | 2005 |
Presynaptic inhibition of corticothalamic feedback by metabotropic glutamate receptors.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Feedback; Ferrets; Geniculate Bodies; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neural Pathways; Neurons; Presynaptic Terminals; Receptors, Metabotropic Glutamate; Synaptic Transmission; Time Factors; Xanthenes | 2005 |
Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramine-induced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands.
Topics: Adaptation, Physiological; Amino Acids; Animals; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds, Heterocyclic; Down-Regulation; Excitatory Amino Acid Antagonists; Hippocampus; Imipramine; Ligands; Male; Mice; Mice, Inbred Strains; Nervous System Physiological Phenomena; Reaction Time; Receptors, Adrenergic, beta; Receptors, Metabotropic Glutamate; Xanthenes | 2005 |
Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity.
Topics: Amino Acids; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Ferrets; Gluconates; Guanosine Diphosphate; In Vitro Techniques; Male; Membrane Potentials; Nerve Net; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Picrotoxin; Receptors, Metabotropic Glutamate; Synapses; Thalamus; Thionucleotides; Xanthenes | 2006 |
Blockade of group II metabotropic glutamate receptors in the nucleus accumbens produces hyperlocomotion in rats previously exposed to amphetamine.
Topics: Amino Acids; Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Drug Interactions; Hyperkinesis; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes | 2006 |
Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus.
Topics: Amino Acids; Animals; Apoptosis; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Excitatory Amino Acid Antagonists; Glutamic Acid; Goldfish; Hypoxia; Hypoxia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Models, Animal; Receptors, Metabotropic Glutamate; Retina; Retinal Diseases; Telencephalon; Xanthenes | 2007 |
Group-II metabotropic glutamate receptor ligands as adjunctive drugs in the treatment of depression: a new strategy to shorten the latency of antidepressant medication?
Topics: Adjuvants, Pharmaceutic; Amino Acids; Animals; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds, Heterocyclic; Depressive Disorder; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Agents; Hippocampus; Imipramine; In Vitro Techniques; Mice; Neurons; Rats; Rats, Inbred Strains; Receptor Cross-Talk; Receptors, Metabotropic Glutamate; Time Factors; Xanthenes | 2007 |
Type-3 metabotropic glutamate receptors negatively modulate bone morphogenetic protein receptor signaling and support the tumourigenic potential of glioma-initiating cells.
Topics: Amino Acids; Animals; Bone Morphogenetic Protein Receptors; Brain Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Humans; Magnetic Resonance Imaging; Mice; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Phosphorylation; Receptors, Metabotropic Glutamate; Signal Transduction; Xanthenes | 2008 |
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain.
Topics: Amino Acids; Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Hydroxamic Acids; Inflammation; Male; Mice; Pain; Pyridines; Receptors, Metabotropic Glutamate; Vorinostat; Xanthenes | 2009 |
Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice.
Topics: Amino Acids; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Frontal Lobe; Hydrolysis; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Phosphatidylinositols; Pyridines; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; Sulfonamides; Xanthenes | 2009 |
Group II metabotropic glutamate receptor activation by agonist LY379268 treatment increases the expression of brain derived neurotrophic factor in the mouse brain.
Topics: Amino Acids; Animals; Brain; Brain-Derived Neurotrophic Factor; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurons; Receptors, Metabotropic Glutamate; RNA, Messenger; Time Factors; Up-Regulation; Xanthenes | 2010 |
Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats.
Topics: Amino Acids; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cognition; Excitatory Amino Acid Agents; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Schizophrenia; Time Factors; Xanthenes | 2010 |
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 an
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Animals; Antipsychotic Agents; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Psychotic Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Transforming Growth Factor beta1; Xanthenes | 2011 |
Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Corpus Striatum; Glycogen Synthase Kinase 3; Male; Motor Activity; Prefrontal Cortex; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Wnt Proteins; Xanthenes | 2011 |
Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata.
Topics: Amino Acids; Animals; Basal Ganglia; Bridged Bicyclo Compounds, Heterocyclic; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Mice; Mice, Knockout; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substantia Nigra; Synaptic Transmission; Xanthenes | 2011 |
Effects of microinjections of Group II metabotropic glutamate agents into the amygdala on sleep.
Topics: Amino Acids; Amygdala; Animals; Arousal; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Microinjections; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Sleep; Sleep, REM; Wakefulness; Xanthenes | 2012 |
Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG).
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; Glycine; Male; Mice; Potassium Chloride; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptosomes; Xanthenes | 2013 |
Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; Dactinomycin; Disks Large Homolog 4 Protein; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intracellular Signaling Peptides and Proteins; Intracellular Space; Membrane Proteins; Neurons; Prefrontal Cortex; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Synapsins; Transcription, Genetic; Xanthenes | 2013 |
Stimulation of metabotropic glutamate (mGlu) 2 receptor and blockade of mGlu1 receptor improve social memory impairment elicited by MK-801 in rats.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memory Disorders; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recognition, Psychology; Xanthenes | 2013 |
mGlu3 receptor blockade inhibits proliferation and promotes astrocytic phenotype in glioma stem cells.
Topics: AC133 Antigen; Amino Acids; Animals; Antigens, CD; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Proliferation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Glioma; Glycoproteins; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Peptides; Phenotype; Receptors, Metabotropic Glutamate; Recombinant Proteins; Transplantation, Heterologous; Xanthenes | 2014 |
Group II mGluRs modulate baseline and arthritis pain-related synaptic transmission in the rat medial prefrontal cortex.
Topics: Amino Acids; Animals; Arthritis, Experimental; Bridged Bicyclo Compounds, Heterocyclic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Kaolin; Miniature Postsynaptic Potentials; Pain; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tissue Culture Techniques; Xanthenes | 2015 |
Activation of mGluR2/3 following stress hormone exposure restores sensitivity to alcohol in rats.
Topics: Alcohol Drinking; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Discrimination Learning; Ethanol; Male; Rats; Rats, Long-Evans; Receptors, AMPA; Self Administration; Xanthenes | 2015 |
Reversal of alcohol dependence-induced deficits in cue-guided behavior via mGluR2/3 signaling in mice.
Topics: Adaptation, Psychological; Alcoholism; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Operant; Consummatory Behavior; Cues; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred C57BL; Psychomotor Performance; Receptors, AMPA; Reward; Self Administration; Signal Transduction; Xanthenes | 2016 |
Amygdala group II mGluRs mediate the inhibitory effects of systemic group II mGluR activation on behavior and spinal neurons in a rat model of arthritis pain.
Topics: Amino Acids; Amygdala; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Carrageenan; Central Amygdaloid Nucleus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kaolin; Nociception; Pain; Posterior Horn Cells; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Vocalization, Animal; Xanthenes | 2019 |
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state.
Topics: Allosteric Regulation; Allosteric Site; Amino Acids; Biphenyl Compounds; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Cell Membrane; Cholesterol Esters; Diosgenin; Disaccharides; Fluorescence Resonance Energy Transfer; Gene Expression; Glucosides; Glutamic Acid; Glycolipids; HEK293 Cells; Humans; Indans; Micelles; Octoxynol; Protein Binding; Protein Conformation; Protein Multimerization; Receptors, Metabotropic Glutamate; Recombinant Proteins; Single Molecule Imaging; Xanthenes | 2021 |