xanomeline has been researched along with pirenzepine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonifazi, A; Del Bello, F; Farande, A; Ferré, S; Matucci, R; Nesi, M; Petrelli, R; Piergentili, A; Quaglia, W; Vistoli, G; Yano, H | 1 |
| Christopoulos, A; El-Fakahany, EE; Parsons, AM | 1 |
| Christopoulos, A; El-Fakahany, EE; Lew, MJ; Parsons, AM | 1 |
| Dai, J; Li, Z; Meltzer, HY; Roseman, AS; Snigdha, S | 1 |
| Dehnicke, C; Deisz, RA; Gigout, S; Horn, P; Lehmann, TN; Wierschke, S | 1 |
6 other study(ies) available for xanomeline and pirenzepine
| Article | Year |
|---|---|
Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1).
Topics: Animals; CHO Cells; Cricetulus; Molecular Docking Simulation; Muscarinic Agonists; Piperidines; Pyridines; Quinolones; Receptor, Muscarinic M1; Structure-Activity Relationship; Thiadiazoles | 2014 |
Advances in CNS Drugs. Recent advances and considerations in the treatment of schizophrenia.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Drug Costs; Drugs, Investigational; Humans; Olanzapine; Pirenzepine; Placebos; Pyridines; Randomized Controlled Trials as Topic; Schizophrenia; Thiadiazoles | 1996 |
Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; CHO Cells; Citrulline; Cricetinae; Humans; Kinetics; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Thiadiazoles; Transfection; Tritium | 1999 |
The assessment of antagonist potency under conditions of transient response kinetics.
Topics: Animals; Artifacts; Atropine; Binding, Competitive; Calcium; Carbachol; CHO Cells; Cricetinae; Drug Antagonism; Humans; Intracellular Fluid; Kinetics; Models, Biological; Monte Carlo Method; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Time Factors | 1999 |
Effect of muscarinic receptor agonists xanomeline and sabcomeline on acetylcholine and dopamine efflux in the rat brain; comparison with effects of 4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one (AC260584) and N-desmethylclozapine
Topics: Acetylcholine; Animals; Antipsychotic Agents; Benzoxazines; Brain; Clozapine; Dopamine; Drug Synergism; Imines; Male; Nucleus Accumbens; Pirenzepine; Prefrontal Cortex; Pyridines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Risperidone; Thiadiazoles | 2008 |
Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex.
Topics: Action Potentials; Adult; Biophysics; Carbachol; Cerebral Cortex; Cholinergic Agonists; Drug Combinations; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; Humans; In Vitro Techniques; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Pyridines; Receptors, Muscarinic; Thiadiazoles | 2012 |