xanomeline has been researched along with atropine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Christopoulos, A; El-Fakahany, EE; Pierce, TL; Sorman, JL | 1 |
| Bang-Andersen, B; Bundgaard, C; Christoffersen, CT; Hentzer, M; Larsen, K; Mikkelsen, GK; Plath, N; Sams, AG | 1 |
| Bernhardt, G; Gmeiner, P; Hübner, H; Keller, M; Pegoli, A; She, X; Wifling, D | 1 |
| Bernhardt, G; Carpenter, J; Chen, M; Gmeiner, P; Gruber, CG; Holliday, ND; Hübner, H; Keller, M; Pegoli, A; She, X; Wan, J; Wifling, D | 1 |
| Christopoulos, A; El-Fakahany, EE; Parsons, AM | 1 |
| Allen, DL; Hoffman, WP; Leiter, PA; Tielking, RL; van Lier, RB; Vidyashankar, AN; Wolff, RK | 1 |
| Christopoulos, A; El-Fakahany, EE; Lew, MJ; Parsons, AM | 1 |
| Cohen, ML; Stengel, PW | 1 |
| El-Fakahany, EE; Jakubík, J; Tucek, S | 1 |
| Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A | 1 |
| Carnicella, S; Oberling, P; Pain, L | 1 |
| De Lorme, KC; El-Fakahany, EE; Grant, MK; Sikorski, KL | 1 |
| El-Fakahany, EE; Grant, MK; Noetzel, MJ | 1 |
| De Lorme, KC; Doležal, V; El-Fakahany, EE; Grant, MK; Jakubík, J; Noetzel, MJ | 1 |
14 other study(ies) available for xanomeline and atropine
| Article | Year |
|---|---|
On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor.
Topics: Animals; Atropine; Carbachol; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Phosphatidylinositols; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Time Factors | 1998 |
Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential.
Topics: Allosteric Regulation; Animals; Benzeneacetamides; Benzoxazines; Brain; Calcium; Cell Line; Cricetinae; Cricetulus; Female; Hepatocytes; Humans; In Vitro Techniques; Male; Maze Learning; Memory, Short-Term; Mice; Nootropic Agents; Oxazines; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Structure-Activity Relationship | 2010 |
Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M
Topics: Benzodiazepinones; Binding Sites; Molecular Dynamics Simulation; Muscarinic Antagonists; Radioisotopes; Receptor, Muscarinic M2 | 2017 |
Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M
Topics: Animals; CHO Cells; Cholinergic Agents; Cricetulus; Fluorescent Dyes; Muscarinic Antagonists; Phthalimides; Protein Structure, Secondary; Quaternary Ammonium Compounds; Receptor, Muscarinic M2 | 2020 |
Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; CHO Cells; Citrulline; Cricetinae; Humans; Kinetics; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Thiadiazoles; Transfection; Tritium | 1999 |
Effects of inhalation exposures to an M1-receptor agonist on ventilation in rhesus monkeys.
Topics: Administration, Inhalation; Airway Resistance; Animals; Atmosphere Exposure Chambers; Atropine; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Administration Schedule; Macaca mulatta; Male; Muscarinic Agonists; Pulmonary Ventilation; Pyridines; Respiration; Thiadiazoles; Tidal Volume | 1999 |
The assessment of antagonist potency under conditions of transient response kinetics.
Topics: Animals; Artifacts; Atropine; Binding, Competitive; Calcium; Carbachol; CHO Cells; Cricetinae; Drug Antagonism; Humans; Intracellular Fluid; Kinetics; Models, Biological; Monte Carlo Method; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Time Factors | 1999 |
Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline.
Topics: Animals; Atropine; Bradycardia; Carbachol; Drug Interactions; Heart; Heart Rate; Imines; In Vitro Techniques; Mice; Muscarinic Agonists; Pyridines; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Thiadiazoles | 2001 |
Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor.
Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; Buffers; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Kinetics; Ligands; Muscarinic Agonists; N-Methylscopolamine; Pyridines; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Tritium | 2002 |
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes | 2003 |
Cholinergic effects on fear conditioning II: nicotinic and muscarinic modulations of atropine-induced disruption of the degraded contingency effect.
Topics: Animals; Atropine; Conditioning, Classical; Fear; Male; Memory; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Oxotremorine; Parasympathetic Fibers, Postganglionic; Pilocarpine; Psychopharmacology; Pyridines; Rats; Rats, Sprague-Dawley; Thiadiazoles | 2005 |
Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor.
Topics: Animals; Atropine; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Drug Interactions; Humans; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Pyridines; Receptor, Muscarinic M1; Thiadiazoles; Time Factors; Transfection; Tritium | 2006 |
Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cell Line, Transformed; Cricetinae; Drug Interactions; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Muscarinic Agonists; N-Methylscopolamine; Phosphatidylinositols; Pilocarpine; Pyridines; Quinuclidinyl Benzilate; Receptor, Muscarinic M3; Thiadiazoles; Time Factors; Transfection | 2009 |
Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor.
Topics: Animals; Atropine; Binding Sites; Carbachol; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Down-Regulation; Humans; Hydrolysis; Muscarinic Agonists; Protein Binding; Pyridines; Receptor, Muscarinic M1; Thiadiazoles | 2010 |