Compounds > xamoterol
Page last updated: 2024-09-04

xamoterol and ketanserin

xamoterol has been researched along with ketanserin in 6 studies

Compound Research Comparison

Studies
(xamoterol)		Trials
(xamoterol)		Recent Studies (post-2010)
(xamoterol)		Studies
(ketanserin)		Trials
(ketanserin)		Recent Studies (post-2010) (ketanserin)
26980173,094335283

Protein Interaction Comparison

ProteinTaxonomyxamoterol (IC50)ketanserin (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0021
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.015
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.015
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.265
5-hydroxytryptamine receptor 1BHomo sapiens (human)6.5
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0184
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0027
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.29
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.015
D(2) dopamine receptorRattus norvegicus (Norway rat)1.8
Synaptic vesicular amine transporterHomo sapiens (human)0.18
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.001

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bernardi, M; Rossini, L; Tonnini, C1
Nagatomo, T; Sasaki, K; Shibata, A; Shimada, K; Wakabayashi, H; Watanabe, K1

Other Studies

6 other study(ies) available for xamoterol and ketanserin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Power spectra of the inter-cycle heart fluctuations in Xenopus laevis (L.), conscious or pithed, exposed to temperature changes and pharmacological treatments].
    Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Body Temperature; Consciousness; Decerebrate State; Heart Conduction System; Heart Rate; Ketanserin; Pressoreceptors; Propanolamines; Receptors, Adrenergic, alpha; Xamoterol; Xenopus laevis

1991
Cardiomyopathic hamster hearts: long-term effects of drugs on catecholamine contents and binding characteristics of alpha 1- and beta 1-adrenergic receptors.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Catecholamines; Cricetinae; Heart; Ketanserin; Mesocricetus; Myocardium; Propanolamines; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Verapamil; Xamoterol

1993