xamoterol has been researched along with atenolol in 16 studies
Studies (xamoterol) | Trials (xamoterol) | Recent Studies (post-2010) (xamoterol) | Studies (atenolol) | Trials (atenolol) | Recent Studies (post-2010) (atenolol) |
---|---|---|---|---|---|
269 | 80 | 17 | 5,473 | 1,950 | 852 |
Protein | Taxonomy | xamoterol (IC50) | atenolol (IC50) |
---|---|---|---|
Beta-1 adrenergic receptor | Homo sapiens (human) | 0.7468 | |
Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.23 | |
Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.23 | |
Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.23 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (37.50) | 18.7374 |
1990's | 2 (12.50) | 18.2507 |
2000's | 5 (31.25) | 29.6817 |
2010's | 3 (18.75) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Faergeman, O; Jensen, HK; Sørensen, EV | 1 |
Lewis, RV; McDevitt, DG; McMurray, J | 1 |
Fitzgerald, DE; Harry, JD | 1 |
Folgering, HT; Lammers, JW; Müller, ME; van Herwaarden, CL | 1 |
Cuspidi, C; Fruscio, M; Gradnik, R; Leonetti, G; Rupoli, L; Sampieri, L; Terzoli, L; Zanchetti, A | 1 |
Briscoe, MG; Halliday, SE; Smith, HJ; Snow, HM | 1 |
Marlow, HF; Morton, PB; O'Neill, PA; Sharman, P; Stark, RD | 1 |
Arnold, IR; Barnett, DB; Mistry, R | 1 |
de Quervain, DJ; Hahn, EL; McGaugh, JL; Nathan, SV; Roozendaal, B | 1 |
Haynes, JM | 1 |
Hashemi-Hezaveh, SM; Sheidadoust, H; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
6 trial(s) available for xamoterol and atenolol
Article | Year |
---|---|
Comparison of the effects of xamoterol, atenolol and propranolol on breathlessness, fatigue and plasma electrolytes during exercise in healthy volunteers.
Topics: Adrenergic beta-Agonists; Adult; Atenolol; Blood Pressure; Calcium; Exercise Test; Fatigue; Heart Rate; Humans; Male; Physical Endurance; Potassium; Propanolamines; Propranolol; Xamoterol | 1991 |
Effects of atenolol, verapamil, and xamoterol on heart rate and exercise tolerance in digitalised patients with chronic atrial fibrillation.
Topics: Adrenergic beta-Agonists; Aged; Atenolol; Atrial Fibrillation; Chronic Disease; Digitalis Glycosides; Exercise Test; Female; Heart Rate; Humans; Lactates; Male; Middle Aged; Propanolamines; Verapamil; Xamoterol | 1989 |
Effect of beta-adrenoceptor agents on the blood flow in carotid arteries in normal volunteers.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Carotid Arteries; Double-Blind Method; Heart Rate; Humans; Male; Propanolamines; Random Allocation; Regional Blood Flow; Xamoterol | 1989 |
A comparative study on the ventilatory and haemodynamic effects of xamoterol and atenolol in asthmatic patients.
Topics: Adrenergic beta-Agonists; Adult; Asthma; Atenolol; Blood Pressure; Double-Blind Method; Forced Expiratory Volume; Heart Rate; Hemodynamics; Humans; Lung; Male; Middle Aged; Peak Expiratory Flow Rate; Propanolamines; Random Allocation; Terbutaline; Vital Capacity; Xamoterol | 1986 |
Does beta 1-selective agonistic activity interfere with the antihypertensive efficacy of beta 1-selective blocking agents?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Benzeneacetamides; Double-Blind Method; Heart Rate; Humans; Hypertension; Propanolamines; Xamoterol | 1985 |
In vivo regulation of human cardiac beta-adrenoceptors by a partial agonist as compared with a full antagonist: selective differences in coupling to adenylate cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angina Pectoris; Atenolol; Double-Blind Method; Down-Regulation; Drug Tolerance; Female; Heart; Humans; Male; Middle Aged; Myocardium; Receptors, Adrenergic, beta; Xamoterol | 1993 |
10 other study(ies) available for xamoterol and atenolol
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Facilitation of calcium blocking and membrane effects by intrinsic sympathomimetic activity.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Calcium; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; In Vitro Techniques; Myocardial Contraction; Propanolamines; Propranolol; Verapamil; Xamoterol | 1984 |
The effects of ICI 118,587 and atenolol on the responses to exercise and on breathlessness in healthy subjects.
Topics: Adult; Atenolol; Double-Blind Method; Heart Rate; Humans; Male; Oxygen Consumption; Physical Exertion; Propanolamines; Random Allocation; Respiration; Xamoterol | 1984 |
Glucocorticoid effects on memory retrieval require concurrent noradrenergic activity in the hippocampus and basolateral amygdala.
Topics: Adrenergic beta-Antagonists; Amygdala; Androstanols; Animals; Atenolol; Corticosterone; Emotions; Escape Reaction; Hippocampus; Hormone Antagonists; Male; Maze Learning; Mental Recall; Propranolol; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Glucocorticoid; Stress, Psychological; Xamoterol | 2004 |
beta(2) and beta(3)-adrenoceptor inhibition of alpha(1)-adrenoceptor-stimulated Ca(2+) elevation in human cultured prostatic stromal cells.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Atenolol; Calcium; Cells, Cultured; Cyclic AMP; Ethanolamines; Humans; Isoproterenol; Male; Phenylephrine; Potassium Channel Blockers; Propanolamines; Propranolol; Prostate; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Stromal Cells; Xamoterol | 2007 |
The possible role of medial prefrontal cortex beta-1-adrenoceptors in morphine-induced amnesia.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Amnesia; Animals; Atenolol; Avoidance Learning; Behavior, Animal; Male; Memory; Morphine; Prefrontal Cortex; Rats, Wistar; Receptors, Adrenergic, beta-1; Xamoterol | 2014 |