Page last updated: 2024-09-03

wye and guanine

wye has been researched along with guanine in 33 studies

Compound Research Comparison

Studies (wye)	Trials (wye)	Recent Studies (post-2010) (wye)	Studies (guanine)	Trials (guanine)	Recent Studies (post-2010) (guanine)
34	0	4	16,278	822	4,809

Protein Interaction Comparison

Protein	Taxonomy	wye (IC50)	guanine (IC50)
Purine nucleoside phosphorylase	Homo sapiens (human)		5

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (78.79)	18.7374
1990's	1 (3.03)	18.2507
2000's	3 (9.09)	29.6817
2010's	3 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Engelhardt, DL; Grunberger, D; Pergolizzi, RG	2
Borek, E; Kasai, H; Kuchino, Y; Nishimura, S; Yamaizumi, Z	1
Schleich, HG; Wintermeyer, W; Zachau, HG	2
Paszyc, S; Rafalska, M	1
Goto, M; Goto, T; Ikeda, K; Kasai, H; Matsuura, S; Mizuno, Y; Sugimoto, T; Takemura, S; Zama, M	1
Gryczynski, I; Johnson, ML; Lakowicz, JR; Wiczk, W	1
Labuda, D; Striker, G; Vega-Martin, MC	1
Ebel, JP; Giegé, R; Krzyzosiak, WJ; Marciniec, T; Romby, P; Wiewiorowski, M	1
Cherek, H; Gryczynski, I; Lakowicz, JR	1
Gryczynski, I; Johnson, ML; Lakowicz, JR	1
Claesens, F; Rigler, R	1
Droogmans, L; Grosjean, H	1
Lakowicz, JR; Wells, BD	1
Hatfield, DL; McNamara, AL; Mushinski, JF; Smith, DW	1
Paulsen, H; Robertson, JM; Wintermeyer, W	2
Ciesiołka, J; Krzyzosiak, WJ	1
Kuechler, E; Lührmann, R; Steiner, G	1
Grunberger, D; Kuchino, Y; Mushinski, JF; Nishimura, S; Pergolizzi, RG	1
Borek, E; Grunberger, D; Kuchino, Y; Mushinski, JF; Nishimura, S	1
Ehrlich, R; Lefevre, JF; Remy, P	1
Barta, A; Kuechler, E; Matzke, AJ	1
Cramer, F; Okabe, N	1
Gryczyński, I; Kawski, A; Nowaczyk, K; Paszyc, S; Skalski, B	1
Golankiewicz, B	1
Carlson, BA; Crain, PF; Hatfield, DL; Henderson, DW; Kwon, SY; Lee, BJ; Mushinski, JF	1
Guymon, R; Hashizume, T; McCloskey, JA; Noon, KR; Sitaramaiah, D; Zhou, S	1
Carlson, BA; Hatfield, DL; Lee, BJ	1
Kumbhar, NM; Sonawane, KD	1
Araya, JC; Bizama, C; Espinoza, JA; García, P; Grez, M; Kunkel, H; Leal, P; Nervi, B; Riquelme, I; Roa, JC; Stein, S; Weber, H	1
Bussi, G; Couture, RM; Gutiérrez-Cánovas, C; Ledesma, JLJ; Ormerod, SJ; Whitehead, PG	1

Reviews

1 review(s) available for wye and guanine

Article	Year
Synthetic and biological applications of tricyclic analogues of guanosine. Acta biochimica Polonica, 1996, Volume: 43, Issue:1 Topics: Acyclovir; Antiviral Agents; Cell Division; Cell Line; Cell Survival; DNA; DNA, Bacterial; Escherichia coli; Ganciclovir; Guanine; Guanosine; Herpesviridae; Humans; Models, Structural; Molecular Structure; Nucleic Acid Conformation; RNA, Transfer, Phe	1996

Other Studies

32 other study(ies) available for wye and guanine

Article	Year
Incorporation of lysine into Y base of phenylalanine tRNA in Vero cells. Nucleic acids research, 1979, Volume: 6, Issue:6 Topics: Animals; Anticodon; Cell Line; Guanine; Haplorhini; Kidney; Lysine; Phenylalanine; Purinones; RNA, Transfer	1979
Under-modified Y base in a tRHAPhe isoacceptor observed in tumor cells. Biochimica et biophysica acta, 1979, Nov-22, Volume: 565, Issue:1 Topics: Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Fluorescence; Guanine; Liver; Mice; Nucleic Acid Precursors; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer, Amino Acyl	1979
Replacement of wybutine by hydrazines and its effect on the active conformation of yeast tRNAPhe. Nucleic acids research, 1978, Volume: 5, Issue:5 Topics: Escherichia coli; Guanine; Hydrazines; Kinetics; Phenylalanine; Phenylalanine-tRNA Ligase; Poly U; Purinones; Ribosomes; RNA, Transfer; Saccharomyces cerevisiae	1978
Photochemical properties of Yt base in aqueous solution. Nucleic acids research, 1979, Volume: 6, Issue:1 Topics: Guanine; Luminescent Measurements; Photochemistry; Purinones; RNA, Transfer; Spectrophotometry, Ultraviolet	1979
Incorporation of amines or hydrazines into tRNA replacing wybutine or dihydrouracil. Methods in enzymology, 1979, Volume: 59 Topics: Amines; Borohydrides; Guanine; Hydrazines; Kinetics; Oxidation-Reduction; Phenylalanine; Purinones; RNA, Transfer; Uracil	1979
Formation of phenylalanine transfer RNA lacking the wye base in Vero cells during methionine starvation. The Journal of biological chemistry, 1978, Sep-25, Volume: 253, Issue:18 Topics: Cell Line; Culture Media; Guanine; Methionine; Nucleic Acid Precursors; Phenylalanine; Purinones; RNA, Transfer	1978
Structure of wye (Yt base) and wyosine (Yt) from Torulopsis utilis phenylalanine transfer ribonucleic acid. Biochemistry, 1976, Feb-24, Volume: 15, Issue:4 Topics: Candida; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Guanine; Guanosine; Mass Spectrometry; Phenylalanine; Purinones; Ribonucleosides; RNA, Transfer; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	1976
Decay time distribution analysis of Yt-base in benzene-methanol mixtures. Journal of photochemistry and photobiology. B, Biology, 1989, Volume: 4, Issue:2 Topics: Benzene; Fluorescent Dyes; Guanine; Methanol; Models, Statistical; Photochemistry; Spectrometry, Fluorescence	1989
The three conformations of the anticodon loop of yeast tRNA(Phe). Journal of biomolecular structure & dynamics, 1989, Volume: 7, Issue:2 Topics: Anticodon; Fluoroimmunoassay; Guanine; Magnesium; Models, Chemical; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Phe; Saccharomyces cerevisiae; Spectrometry, Fluorescence	1989
Characterization of the lead(II)-induced cleavages in tRNAs in solution and effect of the Y-base removal in yeast tRNAPhe. Biochemistry, 1988, Jul-26, Volume: 27, Issue:15 Topics: Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lead; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Phe; Structure-Activity Relationship; Temperature; Urea; Yeasts	1988
Detection of three rotational correlation times for a rigid asymmetric molecule using frequency-domain fluorometry. Biophysical chemistry, 1988, Jul-15, Volume: 30, Issue:3 Topics: Guanine; Mathematics; Models, Theoretical; Molecular Conformation; Spectrometry, Fluorescence	1988
Acrylamide quenching of Yt-base fluorescence in aqueous solution. Biophysical chemistry, 1988, Volume: 31, Issue:3 Topics: Acrylamide; Acrylamides; Guanine; Mathematics; Solutions; Spectrometry, Fluorescence	1988
Conformational dynamics of the anticodon loop in yeast tRNAPhe as sensed by the fluorescence of wybutine. European biophysics journal : EBJ, 1986, Volume: 13, Issue:6 Topics: Anticodon; Escherichia coli; Guanine; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Spectrometry, Fluorescence	1986
Enzymatic conversion of guanosine 3' adjacent to the anticodon of yeast tRNAPhe to N1-methylguanosine and the wye nucleoside: dependence on the anticodon sequence. The EMBO journal, 1987, Volume: 6, Issue:2 Topics: Anticodon; Base Sequence; Guanine; Guanosine; Methylation; Nucleic Acid Conformation; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae	1987
Intensity and anisotropy decays of the Wye base of yeast tRNA(Phe) as measured by frequency-domain fluorometry. Biophysical chemistry, 1987, Volume: 26, Issue:1 Topics: Chelating Agents; Guanine; Magnesium; RNA, Transfer, Amino Acyl; Spectrometry, Fluorescence; Thermodynamics; Yeasts	1987
Tumor-specific, hypomodified phenylalanyl-tRNA is utilized in translation in preference to the fully modified isoacceptor of normal cells. The Journal of biological chemistry, 1985, Jan-10, Volume: 260, Issue:1 Topics: Animals; Cell Line; Globins; Guanine; Liver; Macromolecular Substances; Mice; Mice, Inbred Strains; Neuroblastoma; Peptide Fragments; Protein Biosynthesis; Rabbits; RNA, Transfer, Amino Acyl; Species Specificity	1985
Topological arrangement of two transfer RNAs on the ribosome. Fluorescence energy transfer measurements between A and P site-bound tRNAphe. Journal of molecular biology, 1983, Jun-25, Volume: 167, Issue:2 Topics: Anticodon; Energy Transfer; Escherichia coli; Guanine; Proflavine; Protein Biosynthesis; Ribosomes; RNA, Transfer; RNA, Transfer, Amino Acyl; Spectrometry, Fluorescence	1983
Long-range conformational transition in yeast tRNAPhe, induced by the Y-base removal and detected by chloroacetaldehyde modification. Nucleic acids research, 1983, Oct-11, Volume: 11, Issue:19 Topics: Acetaldehyde; Base Sequence; Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae	1983
Crosslinking transfer RNA and messenger RNA at the ribosomal decoding region: identification of the site of reaction on the messenger RNA. Nucleic acids research, 1984, Nov-12, Volume: 12, Issue:21 Topics: Base Sequence; Chemical Phenomena; Chemistry; Escherichia coli; Guanine; Oligoribonucleotides; Photochemistry; Ribosomes; RNA, Messenger; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae	1984
Alterations in post-transcriptional modification of the Y base in phenylalanine tRNA from tumor cells. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84 Topics: Animals; Base Sequence; Carcinoma, Ehrlich Tumor; Guanine; Liver; Liver Neoplasms, Experimental; Lysine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neuroblastoma; Nucleic Acid Conformation; Rats; RNA Processing, Post-Transcriptional; RNA, Transfer, Amino Acyl	1983
Changes of post-transcriptional modification of wye base in tumor-specific tRNAPhe. Nucleic acids research, 1982, Oct-25, Volume: 10, Issue:20 Topics: Animals; Anticodon; Base Sequence; Carcinoma, Ehrlich Tumor; Guanine; Liver; Mice; Neoplasms, Experimental; Neuroblastoma; Nucleic Acid Conformation; RNA Processing, Post-Transcriptional; RNA, Transfer, Amino Acyl	1982
Fluorimetric study of the complex between yeast phenylalanyl-tRNA synthetase and tRNA-Phe. 1. Changes in the conformation of the enzyme and tRNA; modification of the Wybutine neighbourhood. European journal of biochemistry, 1980, Volume: 103, Issue:1 Topics: Amino Acyl-tRNA Synthetases; Anticodon; Guanine; Nucleic Acid Conformation; Phenylalanine; Phenylalanine-tRNA Ligase; Protein Conformation; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence	1980
Photo-induced crosslinking between phenylalanine transfer RNA and messenger RNA on the Escherichia coli ribosome. European journal of biochemistry, 1980, Volume: 112, Issue:1 Topics: Escherichia coli; Guanine; Light; Phenylalanine; Poly U; Ribosomes; RNA, Fungal; RNA, Messenger; RNA, Transfer; Saccharomyces	1980
Minor conformational changes of yeast tRNAPhe anticodon loop occur upon aminoacylation as indicated by Y base fluorescence. Journal of biochemistry, 1981, Volume: 89, Issue:5 Topics: Anticodon; Fluorescence Polarization; Guanine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae	1981
Effect of ribosome binding and translocation on the anticodon of tRNAPhe as studied by wybutine fluorescence. Nucleic acids research, 1982, Apr-24, Volume: 10, Issue:8 Topics: Anticodon; Escherichia coli; Guanine; Kinetics; Ribosomes; RNA, Transfer; RNA, Transfer, Amino Acyl; Spectrometry, Fluorescence	1982
Temperature effect on the luminescence of synthetized Yt base in PVA film. Biochemical and biophysical research communications, 1981, Feb-27, Volume: 98, Issue:4 Topics: Chemical Phenomena; Chemistry; Guanine; Hot Temperature; Luminescent Measurements; Polyvinyl Alcohol; Quantum Theory	1981
1-Methylguanosine in place of Y base at position 37 in phenylalanine tRNA is responsible for its shiftiness in retroviral ribosomal frameshifting. Virology, 2001, Jan-05, Volume: 279, Issue:1 Topics: Animals; Base Sequence; Frameshifting, Ribosomal; Guanine; Guanosine; Liver; Mice; Molecular Sequence Data; Neuroblastoma; Nucleic Acid Conformation; Rabbits; Reticulocytes; Retroviridae; RNA, Transfer, Phe	2001
Structures of two new "minimalist" modified nucleosides from archaeal tRNA. Bioorganic chemistry, 2004, Volume: 32, Issue:2 Topics: Archaea; Guanine; Mass Spectrometry; Molecular Structure; Nucleosides; RNA, Transfer	2004
Ribosomal frameshifting in response to hypomodified tRNAs in Xenopus oocytes. Biochemical and biophysical research communications, 2008, Oct-10, Volume: 375, Issue:1 Topics: Animals; Base Sequence; Female; Frameshifting, Ribosomal; Guanine; Microinjections; Molecular Sequence Data; Nucleoside Q; Oocytes; Rabbits; RNA, Transfer, Asn; RNA, Transfer, Phe; Xenopus	2008
Iso-energetic multiple conformations of hypermodified nucleic acid base wybutine (yW) which occur at 37(th) position in anticodon loop of tRNA(Phe). Journal of molecular graphics & modelling, 2011, Volume: 29, Issue:7 Topics: Anticodon; Guanine; Molecular Dynamics Simulation; Molecular Structure; Nucleic Acid Conformation; Quantum Theory; RNA, Transfer, Phe	2011
Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice. Oncotarget, 2015, Oct-13, Volume: 6, Issue:31 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Drug Therapy, Combination; Gallbladder Neoplasms; Guanine; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, SCID; Phosphorylation; Signal Transduction; Sirolimus; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2015
Modelling the effects of climate and land-use change on the hydrochemistry and ecology of the River Wye (Wales). The Science of the total environment, 2018, Jun-15, Volume: 627 Topics: Climate Change; Ecology; Ecosystem; Environmental Monitoring; Guanine; Models, Theoretical; Rivers; Wales	2018