Page last updated: 2024-09-03

wy 45911 and wy 48252

wy 45911 has been researched along with wy 48252 in 3 studies

Compound Research Comparison

Studies (wy 45911)	Trials (wy 45911)	Recent Studies (post-2010) (wy 45911)	Studies (wy 48252)	Trials (wy 48252)	Recent Studies (post-2010) (wy 48252)
7	0	0	15	0	0

Protein Interaction Comparison

Protein	Taxonomy	wy 48252 (IC50)
Polyunsaturated fatty acid 5-lipoxygenase	Rattus norvegicus (Norway rat)	3.3
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	6.2
Platelet-activating factor acetylhydrolase	Homo sapiens (human)	2
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	6.2

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kreft, AF; Musser, JH	1
Bender, RH; Carlson, RP; Chang, J; Grimes, D; Hand, JM; Kreft, AF; Kubrak, DM; Musser, JH	1
Auen, MA; Englebach, IM; Hand, JM; Kreft, AF; Musser, JH; Schwalm, SF	1

Reviews

1 review(s) available for wy 45911 and wy 48252

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992

Other Studies

2 other study(ies) available for wy 45911 and wy 48252

Article	Year
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Edema; Guinea Pigs; Hydroxamic Acids; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea	1990
Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea. Prostaglandins, 1989, Volume: 37, Issue:2 Topics: Acetophenones; Airway Resistance; Animals; Chromones; Guinea Pigs; Hydroxyquinolines; In Vitro Techniques; Indazoles; Male; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Trachea	1989

Article

Year

N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.

Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Edema; Guinea Pigs; Hydroxamic Acids; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea

1990

Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea.

Prostaglandins, 1989, Volume: 37, Issue:2

Topics: Acetophenones; Airway Resistance; Animals; Chromones; Guinea Pigs; Hydroxyquinolines; In Vitro Techniques; Indazoles; Male; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Trachea

1989