wy 45911 and wy 48252
wy 45911 has been researched along with wy 48252 in 3 studies
Compound Research Comparison
| Studies (wy 45911) | Trials (wy 45911) | Recent Studies (post-2010) (wy 45911) | Studies (wy 48252) | Trials (wy 48252) | Recent Studies (post-2010) (wy 48252) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 15 | 0 | 0 |
Protein Interaction Comparison
| Protein | Taxonomy | wy 45911 (IC50) | wy 48252 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 3.3 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 6.2 | |
| Platelet-activating factor acetylhydrolase | Homo sapiens (human) | 2 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 6.2 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kreft, AF; Musser, JH | 1 |
| Bender, RH; Carlson, RP; Chang, J; Grimes, D; Hand, JM; Kreft, AF; Kubrak, DM; Musser, JH | 1 |
| Auen, MA; Englebach, IM; Hand, JM; Kreft, AF; Musser, JH; Schwalm, SF | 1 |
Reviews
1 review(s) available for wy 45911 and wy 48252
| Article | Year |
|---|---|
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines | 1992 |
Other Studies
2 other study(ies) available for wy 45911 and wy 48252
| Article | Year |
|---|---|
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Edema; Guinea Pigs; Hydroxamic Acids; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea | 1990 |
Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea.
Topics: Acetophenones; Airway Resistance; Animals; Chromones; Guinea Pigs; Hydroxyquinolines; In Vitro Techniques; Indazoles; Male; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Trachea | 1989 |