Compounds > wy 45911

Page last updated: 2024-09-03

wy 45911 and ly 171883

wy 45911 has been researched along with ly 171883 in 6 studies

Compound Research Comparison

Studies (wy 45911)	Trials (wy 45911)	Recent Studies (post-2010) (wy 45911)	Studies (ly 171883)	Trials (ly 171883)	Recent Studies (post-2010) (ly 171883)
7	0	0	150	4	15

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (66.67)	18.7374
1990's	2 (33.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kreft, AF; Musser, JH	1
Bender, RH; Carlson, RP; Chang, J; Grimes, D; Hand, JM; Kreft, AF; Kubrak, DM; Musser, JH	1
Chang, J; Kubrak, DM; Lewis, AJ; Musser, JH	2
Chang, J; DiZio, SM; Hand, JM; Hite, M; Kubrak, DM; Lewis, AJ; Musser, JH	1
Auen, MA; Englebach, IM; Hand, JM; Kreft, AF; Musser, JH; Schwalm, SF	1

Reviews

1 review(s) available for wy 45911 and ly 171883

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992

Other Studies

5 other study(ies) available for wy 45911 and ly 171883

Article	Year
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Edema; Guinea Pigs; Hydroxamic Acids; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea	1990
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Journal of medicinal chemistry, 1986, Volume: 29, Issue:8 Topics: Animals; Arachidonate Lipoxygenases; Bronchi; Guinea Pigs; Lipoxygenase Inhibitors; Male; Methyl Ethers; Muscle Contraction; Naphthalenes; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Trachea	1986
Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters. Journal of medicinal chemistry, 1987, Volume: 30, Issue:2 Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Fatty Acids; Guinea Pigs; Heterocyclic Compounds; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Neutrophils; Rats; Spectrophotometry, Infrared; SRS-A; Structure-Activity Relationship	1987
Pharmacological characterization using selected antagonists of the leukotriene receptors mediating contraction of guinea-pig trachea. Prostaglandins, 1989, Volume: 37, Issue:2 Topics: Acetophenones; Airway Resistance; Animals; Chromones; Guinea Pigs; Hydroxyquinolines; In Vitro Techniques; Indazoles; Male; Phenyl Ethers; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Tetrazoles; Trachea	1989
Wy-45,911: a novel leukotriene antagonist with lipoxygenase inhibitory activity. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A Topics: Acetophenones; Animals; Arachidonate Lipoxygenases; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Models, Molecular; Molecular Conformation; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles	1987