wy 26703 has been researched along with yohimbine in 8 studies
| Studies (wy 26703) | Trials (wy 26703) | Recent Studies (post-2010) (wy 26703) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 11 | 0 | 0 | 5,893 | 253 | 532 |
| Protein | Taxonomy | wy 26703 (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldwin, JJ; deSolms, SJ; Guare, JP; Huff, JR; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM | 1 |
| Lattimer, N; Rhodes, KF; Waterfall, JF | 1 |
| Pettibone, DJ; Pfleuger, AB; Totaro, JA | 1 |
| Kassarich, J; Lien, EL; Morrison, A; Sullivan, D | 1 |
| De Jonge, A; Doods, HN; Korstanje, C; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B | 1 |
| Antolik, EK; Robinson, EL; Yarbrough, GG | 1 |
| Gadie, B; Lane, AC; McCarthy, PS; Tulloch, IF; Walter, DS | 1 |
| Lattimer, N; McAdams, RP; Rhodes, KF; Sharma, S; Turner, SJ; Waterfall, JF | 1 |
8 other study(ies) available for wy 26703 and yohimbine
| Article | Year |
|---|---|
Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.
Topics: Algorithms; Animals; Binding, Competitive; Cattle; Clonidine; Hydrogen-Ion Concentration; Prazosin; Quinolizines; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine | 1988 |
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine | 1985 |
Comparison of the effects of recently developed alpha 2-adrenergic antagonists with yohimbine and rauwolscine on monoamine synthesis in rat brain.
Topics: 4-Butyrolactone; Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Male; Mianserin; Norepinephrine; Quinolizines; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1985 |
Alpha-2-adrenergic control of prolactin release.
Topics: Animals; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Female; Male; Piperoxan; Pregnancy; Prolactin; Quinolizines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
Topics: Animals; Azepines; Binding, Competitive; Blood Pressure; Clonidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Myocardium; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Antagonism of xylazine plus chloral hydrate loss of the righting reflex in mice. A simple in vivo procedure for the evaluation of selective alpha 2-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Chloral Hydrate; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Mice; Motor Activity; Postural Balance; Quinolizines; Reflex; Thiazines; Xylazine; Yohimbine | 1984 |
2-Alkyl analogue of idazoxan (RX 781094) with enhanced antagonist potency and selectivity at central alpha 2-adrenoceptors in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Kinetics; Male; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1984 |
Alpha 2-adrenoceptor antagonism and other pharmacological antagonist properties of some substituted benzoquinolizines and yohimbine in vitro.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Drug Interactions; Electric Stimulation; Guinea Pigs; Heart; Histamine Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Muscles; Myocardial Contraction; Quinolizines; Rabbits; Rats; Receptors, Muscarinic; Yohimbine | 1984 |