Compounds > wy 26703
Page last updated: 2024-09-04

wy 26703 and prazosin

wy 26703 has been researched along with prazosin in 4 studies

Compound Research Comparison

Studies
(wy 26703)		Trials
(wy 26703)		Recent Studies (post-2010)
(wy 26703)		Studies
(prazosin)		Trials
(prazosin)		Recent Studies (post-2010) (prazosin)
11007,914713682

Protein Interaction Comparison

ProteinTaxonomywy 26703 (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldwin, JJ; deSolms, SJ; Guare, JP; Huff, JR; Hunt, CA; Randall, WC; Sanders, WS; Smith, SJ; Vacca, JP; Zrada, MM1
De Jonge, A; Doods, HN; Korstanje, C; Thoolen, MJ; Timmermans, PB; Van Zwieten, PA; Wilffert, B1
Paciorek, PM; Shepperson, NB1
Gadie, B; Lane, AC; McCarthy, PS; Tulloch, IF; Walter, DS1

Other Studies

4 other study(ies) available for wy 26703 and prazosin

ArticleYear
Structure-affinity relationships of arylquinolizines at alpha-adrenoceptors.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Algorithms; Animals; Binding, Competitive; Cattle; Clonidine; Hydrogen-Ion Concentration; Prazosin; Quinolizines; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Yohimbine

1988
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:4

    Topics: Animals; Azepines; Binding, Competitive; Blood Pressure; Clonidine; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Myocardium; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1984
alpha 1-Adrenoceptor agonist activity of alpha 2-adrenoceptor antagonists in the pithed rat preparation.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxins; Female; Idazoxan; Norepinephrine; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Reserpine; Spinal Cord

1983
2-Alkyl analogue of idazoxan (RX 781094) with enhanced antagonist potency and selectivity at central alpha 2-adrenoceptors in the rat.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Kinetics; Male; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1984