Compounds > wy 26703
Page last updated: 2024-09-04

wy 26703 and idazoxan

wy 26703 has been researched along with idazoxan in 5 studies

Compound Research Comparison

Studies
(wy 26703)		Trials
(wy 26703)		Recent Studies (post-2010)
(wy 26703)		Studies
(idazoxan)		Trials
(idazoxan)		Recent Studies (post-2010) (idazoxan)
11001,49940123

Protein Interaction Comparison

ProteinTaxonomywy 26703 (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lattimer, N; Rhodes, KF; Waterfall, JF1
Pettibone, DJ; Pfleuger, AB; Totaro, JA1
Paciorek, PM; Shepperson, NB1
Antolik, EK; Robinson, EL; Yarbrough, GG1
Gadie, B; Lane, AC; McCarthy, PS; Tulloch, IF; Walter, DS1

Other Studies

5 other study(ies) available for wy 26703 and idazoxan

ArticleYear
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Dioxanes; Dogs; Humans; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Quinolizines; Rabbits; Rats; Rats, Inbred Strains; Saphenous Vein; Species Specificity; Vas Deferens; Yohimbine

1985
Comparison of the effects of recently developed alpha 2-adrenergic antagonists with yohimbine and rauwolscine on monoamine synthesis in rat brain.
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: 4-Butyrolactone; Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Male; Mianserin; Norepinephrine; Quinolizines; Rats; Rats, Inbred Strains; Serotonin; Yohimbine

1985
alpha 1-Adrenoceptor agonist activity of alpha 2-adrenoceptor antagonists in the pithed rat preparation.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxins; Female; Idazoxan; Norepinephrine; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Reserpine; Spinal Cord

1983
Antagonism of xylazine plus chloral hydrate loss of the righting reflex in mice. A simple in vivo procedure for the evaluation of selective alpha 2-adrenoceptor antagonists.
    Journal of pharmacological methods, 1984, Volume: 11, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Chloral Hydrate; Dioxanes; Dose-Response Relationship, Drug; Female; Idazoxan; Mice; Motor Activity; Postural Balance; Quinolizines; Reflex; Thiazines; Xylazine; Yohimbine

1984
2-Alkyl analogue of idazoxan (RX 781094) with enhanced antagonist potency and selectivity at central alpha 2-adrenoceptors in the rat.
    British journal of pharmacology, 1984, Volume: 83, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Dioxanes; Dioxins; Idazoxan; In Vitro Techniques; Kinetics; Male; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine

1984