wr 99210 has been researched along with trimethoprim in 3 studies
| Studies (wr 99210) | Trials (wr 99210) | Recent Studies (post-2010) (wr 99210) | Studies (trimethoprim) | Trials (trimethoprim) | Recent Studies (post-2010) (trimethoprim) |
|---|---|---|---|---|---|
| 59 | 0 | 12 | 6,989 | 845 | 894 |
| Protein | Taxonomy | wr 99210 (IC50) | trimethoprim (IC50) |
|---|---|---|---|
| Chain A, Dihydrofolate reductase | Bacillus anthracis | 77200 | |
| Chain A, dihydrofolate reductase (DHFR) | Bacillus anthracis | 77200 | |
| Dihydrofolate reductase | Mycobacterium avium | 0.2588 | |
| Dihydrofolate reductase | Homo sapiens (human) | 1.8206 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.3493 | |
| Dihydrofolate reductase type 1 | Escherichia coli | 0.25 | |
| Dihydrofolate reductase | Neisseria gonorrhoeae | 0.45 | |
| Thymidylate synthase | Homo sapiens (human) | 3.405 | |
| Dihydrofolate reductase | Staphylococcus aureus | 0.0875 | |
| Thymidylate synthase | Escherichia coli K-12 | 3.405 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.6064 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.01 | |
| Dihydrofolate reductase type 1 from Tn4003 | Staphylococcus aureus | 0.023 | |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 2.7 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.7061 | |
| Dihydrofolate reductase | Candida albicans | 0.1361 | |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | 2.7 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.45 | |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | 2.73 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.8 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 3.2206 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium berghei ANKA | 0.12 | |
| Dihydrofolate reductase | Streptococcus pneumoniae TIGR4 | 0.0297 | |
| Dihydrofolate reductase | Lactococcus lactis subsp. lactis Il1403 | 0.45 | |
| Dihydrofolate reductase | Bacillus anthracis | 4.77 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 1.244 | |
| Dihydrofolate reductase | Pneumocystis jirovecii | 0.092 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Genther, CS; Smith, CS | 1 |
| Borrmann, S; Kiara, SM; Masseno, V; Mwai, L; Nzila, A; Ochola, I; Okombo, J | 1 |
| Jia, Q; Kovacs, JA; Ma, L | 1 |
3 other study(ies) available for wr 99210 and trimethoprim
| Article | Year |
|---|---|
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines | 1977 |
In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.
Topics: Animals; Antimalarials; Folic Acid Antagonists; Genotype; Inhibitory Concentration 50; Kenya; Methotrexate; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Proguanil; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim; Trimetrexate | 2009 |
Development of a yeast assay for rapid screening of inhibitors of human-derived Pneumocystis carinii dihydrofolate reductase.
Topics: Animals; Drug Evaluation, Preclinical; Folic Acid Antagonists; Humans; Pneumocystis; Pneumocystis Infections; Pyrimethamine; Rats; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines; Trimethoprim; Trimetrexate | 2002 |