wr 159412 has been researched along with 2,4-diamino-5-benzylpyrimidine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukunaga, JY; Hansch, C; Jow, PY | 1 |
| Crippen, GM; Ghose, AK | 1 |
| Battershell, C; Hopfinger, AJ; Malhotra, D | 1 |
3 other study(ies) available for wr 159412 and 2,4-diamino-5-benzylpyrimidine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of antimalarial and dihydrofolate reductase inhibition by quinazolines and 5-substituted benzyl-2,4-diaminopyrimidines.
Topics: Animals; Antimalarials; Escherichia coli; Folic Acid Antagonists; Mathematics; Mice; Microbial Sensitivity Tests; Pyrimidines; Quinazolines; Streptococcus; Structure-Activity Relationship | 1977 |
General distance geometry three-dimensional receptor model for diverse dihydrofolate reductase inhibitors.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography; Folic Acid Antagonists; Liver; Models, Chemical; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Rats; Structure-Activity Relationship; Triazines | 1984 |
Inhibition of dihydrofolate reductase: structure-activity correlations of quinazolines based upon molecular shape analysis.
Topics: Chemical Phenomena; Chemistry, Physical; Folic Acid Antagonists; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship | 1981 |