Compounds > wr 1065
Page last updated: 2024-08-26

wr 1065 and spermidine

wr 1065 has been researched along with spermidine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Issels, RD; Meier, T1
Schroeder, KK; Snyder, RD1
Judd, GG; Leyser, A; Mitchell, JL; Rupert, J1
List, AF1
El-Ghissassi, F; Hainaut, P; North, S; Pluquet, O; Verhaegh, G1

Reviews

1 review(s) available for wr 1065 and spermidine

ArticleYear
Use of amifostine in hematologic malignancies, myelodysplastic syndrome, and acute leukemia.
    Seminars in oncology, 1999, Volume: 26, Issue:2 Suppl 7

    Topics: Acute Disease; Amifostine; Animals; Apoptosis; Cytoprotection; Hematologic Neoplasms; Hematopoietic Stem Cells; Humans; Leukemia; Mercaptoethylamines; Molecular Structure; Myelodysplastic Syndromes; Protective Agents; Spermidine; Spermine

1999

Other Studies

4 other study(ies) available for wr 1065 and spermidine

ArticleYear
Degradation of 2-(3-aminopropylamino)-ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of Chinese hamster ovary cells.
    Biochemical pharmacology, 1995, Aug-08, Volume: 50, Issue:4

    Topics: Acrolein; Amifostine; Amine Oxidase (Copper-Containing); Animals; Cell Survival; CHO Cells; Copper; Cricetinae; Culture Media; Cysteamine; Glutathione; Guanidines; Hydrogen Peroxide; Mercaptoethylamines; Oxidoreductases Acting on CH-NH Group Donors; Radiation-Protective Agents; Spermidine

1995
Radiosensitivity of polyamine-depleted HeLa cells and modulation by the aminothiol WR-1065.
    Radiation research, 1994, Volume: 137, Issue:1

    Topics: Cell Survival; Clone Cells; Deoxyadenosines; DNA Damage; Dose-Response Relationship, Radiation; Eflornithine; HeLa Cells; Humans; Kinetics; Mercaptoethylamines; Mitoguazone; Polyamines; Putrescine; Radiation-Protective Agents; Spermidine; Spermine; Time Factors; Tumor Stem Cell Assay; X-Rays

1994
Mammalian cell polyamine homeostasis is altered by the radioprotector WR1065.
    The Biochemical journal, 1998, Oct-15, Volume: 335 ( Pt 2)

    Topics: Animals; Homeostasis; Mercaptoethylamines; Ornithine Decarboxylase; Polyamines; Radiation-Protective Agents; Rats; Spermidine

1998
The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway.
    Oncogene, 2000, Feb-24, Volume: 19, Issue:9

    Topics: 3T3 Cells; Animals; Cell Cycle; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Down-Regulation; Gamma Rays; Humans; Mercaptoethylamines; Mice; Mice, Inbred BALB C; Protein Binding; Radiation-Protective Agents; Signal Transduction; Spermidine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000