Page last updated: 2024-08-26

wr 1065 and cysteamine

wr 1065 has been researched along with cysteamine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's11 (55.00)18.2507
2000's2 (10.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Purdie, JW1
Fahey, RC; Michael, BD; Vojnovic, B1
Carper, SW; Gilligan, BJ; Hall, JS; Madsen, EL; Smith, FL; Storm, FK1
Altschuler, EM; Brock, WA; Murray, D; Prager, A1
Butler, JD; Gahl, WA; Tietze, F1
Fahey, RC; Gonick, G; Newton, GL; Ward, JF; Zheng, S1
Fahey, RC; Smoluk, GD; Ward, JF1
Rix-Montel, MA; Vasilescu, D1
Antoku, S1
Issels, RD; Meier, T1
Aguilera, JA; Fahey, RC; Milligan, JR; Ng, JY; Ward, JF; Wu, CC1
Murray, D; Prager, A; Terry, NH1
Hoffmann, GR; Littlefield, LG; Quaranta, JL; Shorter, RA1
Aguilera, JA; Fahey, RC; Newton, GL; Ward, JF1
Koch, KE; Lubec, G; Roberts, JC1
Kelley, LL; Roberts, JC; Warters, RL; Wilmore, BH1
Buccola, J; Hoffmann, GR; Littlefield, LG; Merz, MS1
Cassidy, PB; Roberts, JC; Warters, RL; Wilmore, BH1
Vos, O1
Cavaille, JP; Graziani, F; Ouari, O; Pietri, S; Robin, M; Stocker, P; Vidal, N1

Other Studies

20 other study(ies) available for wr 1065 and cysteamine

ArticleYear
A comparative study of the radioprotective effects of cysteamine, WR-2721, and WR-1065 in cultured human cells.
    Radiation research, 1979, Volume: 77, Issue:2

    Topics: Amifostine; Cell Line; Cell Survival; Cysteamine; Diamines; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Mercaptoethylamines; Organothiophosphorus Compounds; Radiation-Protective Agents; Time Factors

1979
The effects of counter-ion condensation and co-ion depletion upon the rates of chemical repair of poly(U) radicals by thiols.
    International journal of radiation biology, 1991, Volume: 59, Issue:4

    Topics: Cysteamine; Cysteine; Electric Conductivity; Electrons; Glutathione; In Vitro Techniques; Ions; Mercaptoethanol; Mercaptoethylamines; Mesna; Particle Accelerators; Poly U; Pulse Radiolysis; Radiation-Protective Agents; Sulfhydryl Compounds

1991
Cellular effects of piezoelectric versus electrohydraulic high energy shock waves.
    The Journal of urology, 1992, Volume: 147, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Cell Division; Cell Line; Cell Survival; Colony-Forming Units Assay; Cricetinae; Cricetulus; Cysteamine; Female; Idoxuridine; L-Lactate Dehydrogenase; Lithotripsy; Mercaptoethylamines; Methionine Sulfoximine; Ovary; Radiation-Protective Agents

1992
Effect of thiols on micronucleus frequency in gamma-irradiated mammalian cells.
    Mutation research, 1991, Volume: 247, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae; Cysteamine; Cytochalasin B; DNA Repair; Dose-Response Relationship, Drug; Gamma Rays; Mercaptoethylamines; Micronucleus Tests; Regression Analysis; Sulfhydryl Compounds

1991
Cystine depletion by WR-1065 in cystinotic cells. Mechanism of action.
    Biochemical pharmacology, 1985, Jun-15, Volume: 34, Issue:12

    Topics: Amifostine; Child; Child, Preschool; Cysteamine; Cystine; Cystinosis; Humans; In Vitro Techniques; Mercaptoethylamines; Radiation-Protective Agents; Sulfur Radioisotopes

1985
Radioprotection of DNA by thiols: relationship between the net charge on a thiol and its ability to protect DNA.
    Radiation research, 1988, Volume: 114, Issue:1

    Topics: Anions; Cations; Cysteamine; Dithiothreitol; DNA; DNA Damage; Glutathione; Mercaptoethanol; Mercaptoethylamines; Mesna; Radiation-Protective Agents; Sulfhydryl Compounds; Thiomalates

1988
Interaction of glutathione and other low-molecular-weight thiols with DNA: evidence for counterion condensation and coion depletion near DNA.
    Radiation research, 1988, Volume: 114, Issue:1

    Topics: Anions; Cations; Cysteamine; DNA; Glutathione; Mercaptoethylamines; Mesna; Sulfhydryl Compounds; Thiomalates; Ultrasonics

1988
Interaction of sulfur-containing radioprotectors with DNA: a spectrophotometric study.
    Physiological chemistry and physics, 1980, Volume: 12, Issue:1

    Topics: Amifostine; Chemical Phenomena; Chemistry, Physical; Cystaphos; Cysteamine; Diamines; DNA, Bacterial; Escherichia coli; Mercaptoethylamines; Nucleic Acid Denaturation; Radiation-Protective Agents; Spectrophotometry, Ultraviolet

1980
Protection of cultured mammalian cells by S-2-(3-aminopropylamino)ethylphosphorothioic acid(WR-2721).
    International journal of radiation oncology, biology, physics, 1983, Volume: 9, Issue:10

    Topics: Amifostine; Animals; Cells, Cultured; Cobalt Radioisotopes; Cysteamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Leukemia L5178; Leukemia, Experimental; Liver; Mercaptoethylamines; Mice; Organothiophosphorus Compounds; Radiation-Protective Agents; Time Factors; Tissue Extracts

1983
Degradation of 2-(3-aminopropylamino)-ethanethiol (WR-1065) by Cu-dependent amine oxidases and influence on glutathione status of Chinese hamster ovary cells.
    Biochemical pharmacology, 1995, Aug-08, Volume: 50, Issue:4

    Topics: Acrolein; Amifostine; Amine Oxidase (Copper-Containing); Animals; Cell Survival; CHO Cells; Copper; Cricetinae; Culture Media; Cysteamine; Glutathione; Guanidines; Hydrogen Peroxide; Mercaptoethylamines; Oxidoreductases Acting on CH-NH Group Donors; Radiation-Protective Agents; Spermidine

1995
DNA repair by thiols in air shows two radicals make a double-strand break.
    Radiation research, 1995, Volume: 143, Issue:3

    Topics: Cysteamine; Dimethyl Sulfoxide; DNA; DNA Damage; DNA Repair; Free Radical Scavengers; Free Radicals; Mercaptoethylamines; Osmolar Concentration; Sulfhydryl Compounds

1995
Influence of intracellular thiol and polyamine levels on radioprotection by aminothiols.
    International journal of radiation biology, 1993, Volume: 64, Issue:1

    Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Cysteamine; Dithiothreitol; Dose-Response Relationship, Radiation; Glutathione; Mercaptoethylamines; Polyamines; Radiation Tolerance; Radiation-Protective Agents; Sulfhydryl Compounds

1993
Modulation of bleomycin-induced mitotic recombination in yeast by the aminothiols cysteamine and WR-1065.
    Molecular & general genetics : MGG, 1995, Dec-10, Volume: 249, Issue:4

    Topics: Alleles; Antibiotics, Antineoplastic; Bleomycin; Cysteamine; Fungal Proteins; Gene Conversion; Gene Expression Regulation, Fungal; Mercaptoethylamines; Mitosis; Mutagenesis; Oxygen; Saccharomyces cerevisiae

1995
Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei.
    Radiation research, 1996, Volume: 146, Issue:3

    Topics: Animals; Cell Line; Cell Nucleus; Chromatin; Cricetinae; Cricetulus; Cysteamine; Cysteine; Disulfides; Glutathione; Histones; Magnesium Chloride; Mercaptoethylamines; Radiation-Protective Agents; Spermine; Structure-Activity Relationship; Sulfhydryl Compounds

1996
Radiation protection by alpha-methyl-homocysteine thiolactone in vitro.
    Life sciences, 1997, Volume: 60, Issue:6

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Cesium Radioisotopes; Cricetinae; Cricetulus; Cysteamine; Cysteine; Homocysteine; Mercaptoethylamines; Radiation Dosage; Radiation-Protective Agents; Radiation, Ionizing

1997
Modulation of radiation-induced apoptosis by thiolamines.
    International journal of radiation biology, 1997, Volume: 72, Issue:4

    Topics: Animals; Apoptosis; Cysteamine; Cysteine; HL-60 Cells; Humans; Hybridomas; Mercaptoethylamines; Mice; Prodrugs; Radiation-Protective Agents; T-Lymphocytes

1997
Structure-activity analysis of the potentiation by aminothiols of the chromosome-damaging effect of bleomycin in G0 human lymphocytes.
    Environmental and molecular mutagenesis, 2001, Volume: 37, Issue:2

    Topics: Bleomycin; Chromosome Aberrations; Cysteamine; Drug Synergism; Humans; Lymphocytes; Mercaptoethylamines; Micronucleus Tests; Resting Phase, Cell Cycle; Structure-Activity Relationship

2001
Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Animals; Antimutagenic Agents; Cell Death; Cell Line; Cricetinae; Cricetulus; Cysteamine; Cysteine; Gamma Rays; Mercaptoethylamines; Mutagenicity Tests; Prodrugs; Radiation-Protective Agents; Structure-Activity Relationship; Sugar Alcohols; Thiazoles; Thiazolidines

2001
Role of endogenous thiols in protection.
    Advances in space research : the official journal of the Committee on Space Research (COSPAR), 1992, Volume: 12, Issue:2-3

    Topics: Amifostine; Animals; Cells; Cysteamine; DNA Damage; DNA Repair; Free Radical Scavengers; Glutathione; Humans; Mercaptoethylamines; Prostaglandins; Radiation Injuries; Radiation Tolerance; Radiation-Protective Agents; Radiation, Ionizing; Sulfhydryl Compounds

1992
High throughput assay for evaluation of reactive carbonyl scavenging capacity.
    Redox biology, 2014, Volume: 2

    Topics: Aldehydes; Animals; Caco-2 Cells; Cell Line, Tumor; Cysteamine; Cysteine; Glycation End Products, Advanced; High-Throughput Screening Assays; Humans; Mercaptoethylamines; Mice; Pyruvaldehyde; Sensitivity and Specificity; Serum Albumin, Bovine

2014