wogonin has been researched along with sesamin* in 1 studies
1 other study(ies) available for wogonin and sesamin
Article | Year |
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Simultaneous determination of asarinin, β-eudesmol, and wogonin in rats using ultraperformance liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic studies following administration of standards and Gumiganghwal-tang.
Asarinin, β-eudesmol, and wogonin have common antiangiogenic activities and have the potential for use in chemotherapy. Besides, they are multivalent substances that are combined in various herbal medicines. The purpose of this study was to develop a method for simultaneous analysis of asarinin, β-eudesmol, and wogonin, which are representative pharmacological components of Asarum heterotropoides, Atractylodes lancea, and Scutellaria baicalensis, respectively, in rat biosamples using ultraperformance liquid chromatography-tandem mass spectrometry. The three components were separated using 5 mm aqueous ammonium acetate containing 0.1% formic acid and acetonitrile as a mobile phase, equipped with a KINETEX core-shell C Topics: Animals; Chromatography, High Pressure Liquid; Dioxoles; Flavanones; Lignans; Linear Models; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes, Eudesmane; Tandem Mass Spectrometry | 2021 |