Page last updated: 2024-09-04

withanolide d and withanolides

withanolide d has been researched along with withanolides in 22 studies

Compound Research Comparison

Studies
(withanolide d)
Trials
(withanolide d)
Recent Studies (post-2010)
(withanolide d)
Studies
(withanolides)
Trials
(withanolides)
Recent Studies (post-2010) (withanolides)
250117891647

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.64)18.7374
1990's0 (0.00)18.2507
2000's7 (31.82)29.6817
2010's11 (50.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Chowdhury, K; Neogy, RK1
Casinovi, CG; Maione, AM; Romeo, A1
Chakraborti, SK; Chatterjee, S1
Jha, S; Ray, S1
Choudhary, MI; Ganzera, M; Khan, IA1
Maldonado, E; Martínez, M; Pérez-Castorena, AL; Torres, FR1
Bargagna-Mohan, P; Mohan, R; Ravindranath, PP1
Bandyopadhyay, M; Jha, S; Tepfer, D1
Chang, FR; Chen, JH; Chen, SL; Chiang, MY; Hsieh, PW; Huang, ZY; Hung, WC; Lübken, T; Wu, CC; Wu, YC; Yang, YL; Yen, HF; Yen, MH1
Aristizábal, FA; Cordero, CP; Morantes, SJ; Páez, A; Rincón, J1
Aliouat, el M; Alkhatib, R; Bailleul, F; Biabiany, M; Hennebelle, T; Joha, S; Joseph, H; Pottier, M; Quesnel, B; Roumy, V; Sahpaz, S1
Chandra, S; Mandal, C; Mondal, S; Sangwan, R1
Bhattacharya, K; Mallick, A; Mandal, C; Mondal, S; Sangwan, R1
Maity, R; Mallick, A; Mandal, C; Misra-Bhattacharya, S; Mondal, S; Roy, S; Sangwan, R1
Avasarala, H; Dinakaran, SK; Ghosh, S; Kanthasamy, N; Karanam, SR; Macharala, SP; Prabhakaran, Y1
Mandal, C; Sangwan, R; Sarkar, S1
Darokar, MP; Joshi, P; Misra, L; Sangwan, NS; Siddique, AA1
Kumar, G; Patnaik, R1
Che, Y; Geng, B; Hu, S; Liu, Z; Lv, Y; Mu, X; Pan, J; Shen, J; Shi, W; Wang, C; Wen, H; Xu, C; Xu, Y; Yang, J; You, Q; Zhang, C; Zhang, J; Zhao, T1
Batista, PHJ; Gunatilaka, AAL; Mafezoli, J; Minguzzi, S; Oliveira, MCF; Pessoa, ODL; Whitesell, L; Wijeratne, EMK; Xu, YM1
Alves, BG; de Figueiredo, JR; de Lima, LF; de Sá, NAR; Deusdênia Loiola, O; Guerreiro, DD; Lobo, CH; Ribeiro Rodrigues, AP; Smitz, J; Tetaping, GM1
Choi, SM; Dash, R; Hannan, MA; Haque, MN; Moon, IS1

Reviews

1 review(s) available for withanolide d and withanolides

ArticleYear
Withanolide D, carrying the baton of Indian rasayana herb as a lead candidate of antileukemic agent in modern medicine.
    Advances in experimental medicine and biology, 2012, Volume: 749

    Topics: Adjuvants, Immunologic; Apoptosis; Ceramides; Herbal Medicine; Humans; Leukemia; Medicine, Ayurvedic; Withanolides

2012

Other Studies

21 other study(ies) available for withanolide d and withanolides

ArticleYear
Mode of action of Withaferin A and Withanolide D.
    Biochemical pharmacology, 1975, Apr-15, Volume: 24, Issue:8

    Topics: Animals; Antineoplastic Agents; Cholestenes; Cholestenones; Depression, Chemical; Ethers, Cyclic; Lactones; Male; Mice; Neoplasm Transplantation; Phenylalanine; RNA, Neoplasm; Sarcoma 180; Transplantation, Homologous; Uracil; Withanolides

1975
A convenient preparation of the side-chain lactone ring of a withanolide precursor.
    Steroids, 1989, Volume: 54, Issue:3

    Topics: Aldehydes; Chemical Phenomena; Chemistry; Ergosterol; Glutarates; Hydroxides; Potassium; Potassium Compounds; Pyrones; Withanolides

1989
Antimicrobial activities of some antineoplastic and other withanolides.
    Antonie van Leeuwenhoek, 1980, Volume: 46, Issue:1

    Topics: Antineoplastic Agents; Aspergillus niger; Bacillus; Bacteria; Candida albicans; Enterobacteriaceae; Ergosterol; Fungi; Lactones; Saccharomyces cerevisiae; Staphylococcus aureus; Structure-Activity Relationship; Withanolides

1980
Production of withaferin A in shoot cultures of Withania somnifera.
    Planta medica, 2001, Volume: 67, Issue:5

    Topics: Adenine; Agar; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Carbon; Culture Media; Culture Techniques; Ergosterol; Kinetin; Plant Extracts; Plant Growth Regulators; Plant Shoots; Purines; Solanaceae; Withanolides

2001
Quantitative HPLC analysis of withanolides in Withania somnifera.
    Fitoterapia, 2003, Volume: 74, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Ergosterol; Humans; Phytotherapy; Plant Extracts; Plant Leaves; Plant Roots; Plant Stems; Reproducibility of Results; Withania; Withanolides

2003
18-Acetoxywithanolides from Physalis chenopodifolia1.
    Planta medica, 2004, Volume: 70, Issue:1

    Topics: Ergosterol; Flowers; Humans; Magnetic Resonance Spectroscopy; Physalis; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Withanolides; X-Ray Diffraction

2004
Small molecule anti-angiogenic probes of the ubiquitin proteasome pathway: potential application to choroidal neovascularization.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:9

    Topics: Angiogenesis Inhibitors; Blotting, Western; Cells, Cultured; Choroid; Choroidal Neovascularization; Endothelium, Vascular; Ergosterol; Growth Substances; Heme Oxygenase-1; Humans; I-kappa B Proteins; Neovascularization, Physiologic; NF-KappaB Inhibitor alpha; Plant Extracts; Plants, Medicinal; Proteasome Endopeptidase Complex; Ubiquitin; Umbilical Veins; Withanolides

2006
Changes in morphological phenotypes and withanolide composition of Ri-transformed roots of Withania somnifera.
    Plant cell reports, 2007, Volume: 26, Issue:5

    Topics: Biological Factors; DNA, Bacterial; DNA, Plant; Ergosterol; Mutagenesis, Insertional; Phenotype; Plant Roots; Plants, Genetically Modified; Polymerase Chain Reaction; Rhizobium; Time Factors; Transformation, Genetic; Withania; Withanolides

2007
Cytotoxic withanolides from Tubocapsicum anomalum.
    Journal of natural products, 2007, Volume: 70, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Ergosterol; Humans; Molecular Conformation; Molecular Structure; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Solanaceae; Taiwan; Withanolides

2007
Cytotoxicity of withanolides isolated from Acnistus arborescens.
    Fitoterapia, 2009, Volume: 80, Issue:6

    Topics: 2S Albumins, Plant; Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Ergosterol; Fibroblasts; HeLa Cells; Humans; Neoplasms; Phytotherapy; Plant Extracts; Solanaceae; Withanolides

2009
Antifungal and cytotoxic activity of withanolides from Acnistus arborescens.
    Journal of natural products, 2010, Jul-23, Volume: 73, Issue:7

    Topics: Antifungal Agents; Benzamides; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Guadeloupe; Humans; Imatinib Mesylate; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Plant Leaves; Plants, Medicinal; Pneumocystis carinii; Pyrimidines; Solanaceae; Stereoisomerism; Withanolides

2010
Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
    Molecular cancer, 2010, Sep-13, Volume: 9

    Topics: Aniline Compounds; Apoptosis; Benzylidene Compounds; Blotting, Western; Cell Line, Tumor; Ceramides; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia; MAP Kinase Kinase 3; MAP Kinase Kinase 4; MAP Kinase Kinase 6; MAP Kinase Kinase 7; Microscopy, Electron, Scanning; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sphingomyelin Phosphodiesterase; Tumor Cells, Cultured; Withanolides

2010
Bak compensated for Bax in p53-null cells to release cytochrome c for the initiation of mitochondrial signaling during Withanolide D-induced apoptosis.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Cytochromes c; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Signal Transduction; Tumor Suppressor Protein p53; Withanolides

2012
Molecular docking studies of withanolides against Cox-2 enzyme.
    Pakistan journal of pharmaceutical sciences, 2012, Volume: 25, Issue:3

    Topics: Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Models, Molecular; Protein Interaction Domains and Motifs; Withanolides

2012
Coupling G2/M arrest to the Wnt/β-catenin pathway restrains pancreatic adenocarcinoma.
    Endocrine-related cancer, 2014, Volume: 21, Issue:1

    Topics: Apoptosis; beta Catenin; Cadherins; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Flow Cytometry; G2 Phase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Pancreatic Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA; Withanolides; Wnt Signaling Pathway

2014
5,6-de-epoxy-5-en-7-one-17-hydroxy withaferin A, a new cytotoxic steroid from Withania somnifera L. Dunal leaves.
    Natural product research, 2014, Volume: 28, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Drug Screening Assays, Antitumor; Female; Humans; India; Male; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plant Roots; Withania; Withanolides

2014
Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study.
    Medical hypotheses, 2016, Volume: 92

    Topics: Allosteric Site; Blood-Brain Barrier; Humans; Ligands; Molecular Conformation; Molecular Docking Simulation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotection; Phytochemicals; Receptors, N-Methyl-D-Aspartate; Sitosterols; Withania; Withanolides

2016
Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:4

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Lactic Acid; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Receptors, Immunologic; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Withanolides

2018
Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.
    Journal of natural products, 2018, 04-27, Volume: 81, Issue:4

    Topics: Biological Products; Cell Line; Cell Line, Tumor; Cytotoxins; Heat-Shock Response; HEK293 Cells; Humans; Iodine; Organophosphorus Compounds; Sarcoma, Ewing; Structure-Activity Relationship; Withanolides

2018
In vitro study of Withanolide D toxicity on goat preantral follicles and its effects on the cell cycle.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 84

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Female; Goats; Ovarian Follicle; Withanolides

2019
Integrated System Pharmacology and
    CNS & neurological disorders drug targets, 2020, Volume: 19, Issue:7

    Topics: Alzheimer Disease; Computer Simulation; Glycogen Synthase Kinase 3 beta; Humans; Phosphatidylinositol 3-Kinases; Plant Extracts; Sitosterols; Withania; Withanolides

2020