Page last updated: 2024-09-04

withanolide d and bortezomib

withanolide d has been researched along with bortezomib in 1 studies

Compound Research Comparison

Studies (withanolide d)	Trials (withanolide d)	Recent Studies (post-2010) (withanolide d)	Studies (bortezomib)	Trials (bortezomib)	Recent Studies (post-2010) (bortezomib)
25	0	11	6,868	860	4,753

Protein Interaction Comparison

Protein	Taxonomy	bortezomib (IC50)
Proteasome subunit beta type-11	Homo sapiens (human)	0.3213
26S proteasome non-ATPase regulatory subunit 11	Homo sapiens (human)	0.5335
26S proteasome non-ATPase regulatory subunit 12	Homo sapiens (human)	0.5335
26S proteasome non-ATPase regulatory subunit 14	Homo sapiens (human)	0.5335
Proteasome subunit alpha type-7	Homo sapiens (human)	0.3213
Histone deacetylase 3	Homo sapiens (human)	1.18
26S proteasome non-ATPase regulatory subunit 3	Homo sapiens (human)	0.5335
Cathepsin G	Homo sapiens (human)	1.81
Lysosomal protective protein	Homo sapiens (human)	9.2
26S proteasome regulatory subunit 6A	Homo sapiens (human)	0.5335
Nuclear factor NF-kappa-B p105 subunit	Homo sapiens (human)	0.085
Proteasome subunit beta type-1	Homo sapiens (human)	0.2149
Chymase	Homo sapiens (human)	1.19
Proteasome subunit alpha type-1	Homo sapiens (human)	0.3213
Proteasome subunit alpha type-2	Homo sapiens (human)	0.3213
Proteasome subunit alpha type-3	Homo sapiens (human)	0.3213
Proteasome subunit alpha type-4	Homo sapiens (human)	0.3213
Proteasome subunit beta type-8	Homo sapiens (human)	0.1681
Proteasome subunit beta type-8	Mus musculus (house mouse)	0.0168
Proteasome subunit beta type-9	Homo sapiens (human)	0.2059
Proteasome subunit alpha type-5	Homo sapiens (human)	0.3213
Proteasome subunit beta type-4	Homo sapiens (human)	0.3213
Proteasome subunit beta type-6	Homo sapiens (human)	0.2842
Proteasome subunit beta type-5	Homo sapiens (human)	0.1407
26S proteasome regulatory subunit 7	Homo sapiens (human)	0.5335
Lon protease homolog, mitochondrial	Homo sapiens (human)	0.183
Proteasome subunit beta type-10	Homo sapiens (human)	0.5359
26S proteasome regulatory subunit 6B	Homo sapiens (human)	0.5335
26S proteasome non-ATPase regulatory subunit 8	Homo sapiens (human)	0.5335
Proteasome subunit beta type-3	Homo sapiens (human)	0.3213
Proteasome subunit beta type-2	Homo sapiens (human)	0.9297
26S proteasome non-ATPase regulatory subunit 7	Homo sapiens (human)	0.5335
26S proteasome non-ATPase regulatory subunit 4	Homo sapiens (human)	0.5335
26S proteasome complex subunit SEM1	Homo sapiens (human)	0.5335
Proteasome subunit alpha type-6	Homo sapiens (human)	0.3213
26S proteasome regulatory subunit 4	Homo sapiens (human)	0.5335
26S proteasome regulatory subunit 8	Homo sapiens (human)	0.5335
26S proteasome regulatory subunit 10B	Homo sapiens (human)	0.5335
Nuclear factor NF-kappa-B p100 subunit	Homo sapiens (human)	0.085
Transcription factor p65	Homo sapiens (human)	0.085
26S proteasome non-ATPase regulatory subunit 2	Homo sapiens (human)	0.5335
Histone deacetylase 1	Homo sapiens (human)	0.62
26S proteasome non-ATPase regulatory subunit 6	Homo sapiens (human)	0.5335
Proteasomal ubiquitin receptor ADRM1	Homo sapiens (human)	0.5335
ATP-dependent Clp protease proteolytic subunit	Staphylococcus aureus subsp. aureus NCTC 8325	5.3
NACHT, LRR and PYD domains-containing protein 3	Mus musculus (house mouse)	0.0407
Proteasome subunit alpha-type 8	Homo sapiens (human)	0.3213
Histone deacetylase 2	Homo sapiens (human)	0.8
Proteasome subunit beta type-7	Homo sapiens (human)	0.3213
26S proteasome non-ATPase regulatory subunit 1	Homo sapiens (human)	0.5335
Histone deacetylase 8	Homo sapiens (human)	0.072
26S proteasome non-ATPase regulatory subunit 13	Homo sapiens (human)	0.5335

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (100.00)	2.80

Authors

Authors	Studies
Cuendet, M; Freitas Misakyan, MF; Gunatilaka, AAL; Issa, ME; Monteillier, A; Wijeratne, EMK; Xu, YM	1

Other Studies

1 other study(ies) available for withanolide d and bortezomib

Article	Year
Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model. Journal of natural products, 2021, 08-27, Volume: 84, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Coculture Techniques; Humans; Molecular Structure; Multiple Myeloma; Structure-Activity Relationship; Withania; Withanolides	2021

Article

Year

Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model.

Journal of natural products, 2021, 08-27, Volume: 84, Issue:8

Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Coculture Techniques; Humans; Molecular Structure; Multiple Myeloma; Structure-Activity Relationship; Withania; Withanolides

2021