win 52084 and isoxazoles

win 52084 has been researched along with isoxazoles in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's6 (37.50)18.2507
2000's8 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diana, GD; Dutko, FJ; Fox, MP; McKinlay, MA1
Badger, J; Dutko, FJ; Fancher, M; Heinz, BA; McKinlay, MA; Rossmann, MG; Rueckert, RR; Shepard, DA; Smith, TJ1
Arnold, E; Diana, GD; Kamer, G; Kremer, MJ; Luo, M; McKinlay, MA; Otto, MJ; Rossmann, MG; Smith, TJ; Vriend, G1
Hadfield, AT; Heinz, BA; Kim, KH; Kremer, MJ; Minor, I; Oliveira, MA; Pevear, DC; Rossmann, MG; Rueckert, RR; Shepard, D1
Phelps, DK; Post, CB2
Phelps, DK; Post, CB; Rossky, PJ1
Bothner, B; Lewis, JK; Siuzdak, G; Smith, TJ1
Brooks, BR; Post, CB; Speelman, B1
Blaas, D; Kenndler, E; Nizet, S; Okun, VM1
Kurihara, Y; Umeyama, H; Yoneda, S; Yoneda, T1
Bäuml, E; Benie, AJ; Blaas, D; Moser, R; Peters, T1
Chase, E; Harris, K; Katpally, U; Reisdorph, N; Siuzdak, G; Smith, TJ; Thomas, JJ1
Li, Y; Post, CB; Zhou, Z1
Gonçalves, RB; Katpally, U; Mendes, YS; Oliveira, AC; Silva, JL; Smith, TJ; Soares, MR1
Katpally, U; Smith, TJ1

Other Studies

16 other study(ies) available for win 52084 and isoxazoles

ArticleYear
Binding affinities of structurally related human rhinovirus capsid-binding compounds are related to their activities against human rhinovirus type 14.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:6

    Topics: Antiviral Agents; Capsid; Cells, Cultured; Dose-Response Relationship, Drug; Half-Life; Humans; Isoxazoles; Kinetics; Microbial Sensitivity Tests; Rhinovirus

1991
Genetic and molecular analyses of spontaneous mutants of human rhinovirus 14 that are resistant to an antiviral compound.
    Journal of virology, 1989, Volume: 63, Issue:6

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; HeLa Cells; Humans; Isoxazoles; Models, Molecular; Molecular Conformation; Molecular Structure; Mutation; Oxazoles; Rhinovirus; Viral Plaque Assay

1989
The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating.
    Science (New York, N.Y.), 1986, Sep-19, Volume: 233, Issue:4770

    Topics: Antiviral Agents; Binding Sites; Chemical Phenomena; Chemistry; Humans; Isoxazoles; Poliovirus; Rhinovirus; X-Ray Diffraction

1986
Structural studies on human rhinovirus 14 drug-resistant compensation mutants.
    Journal of molecular biology, 1995, Oct-13, Volume: 253, Issue:1

    Topics: Antiviral Agents; Binding, Competitive; Capsid; Crystallography, X-Ray; Drug Resistance, Microbial; Humans; Intercellular Adhesion Molecule-1; Isoxazoles; Mutation; Protein Conformation; Receptors, Virus; Rhinovirus; Viral Proteins

1995
A novel basis of capsid stabilization by antiviral compounds.
    Journal of molecular biology, 1995, Dec-08, Volume: 254, Issue:4

    Topics: Antiviral Agents; Binding Sites; Capsid; Isoxazoles; Models, Chemical; Models, Molecular; Protein Conformation; Rhinovirus; Temperature; Viral Core Proteins

1995
Influence of an antiviral compound on the temperature dependence of viral protein flexibility and packing: a molecular dynamics study.
    Journal of molecular biology, 1998, Feb-20, Volume: 276, Issue:2

    Topics: Antiviral Agents; Capsid; Computer Simulation; Isoxazoles; Models, Molecular; Protein Conformation; Rhinovirus; Temperature

1998
Antiviral agent blocks breathing of the common cold virus.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jun-09, Volume: 95, Issue:12

    Topics: Antiviral Agents; Humans; Isoxazoles; Protein Conformation; Rhinovirus; Viral Proteins; Virus Assembly

1998
Molecular dynamics investigation of the effect of an antiviral compound on human rhinovirus.
    Protein science : a publication of the Protein Society, 1999, Volume: 8, Issue:11

    Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; Calorimetry; Humans; Isoxazoles; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Rhinovirus; Thermodynamics; Viral Proteins

1999
Molecular dynamics simulations of human rhinovirus and an antiviral compound.
    Biophysical journal, 2001, Volume: 80, Issue:1

    Topics: Antiviral Agents; Biophysical Phenomena; Biophysics; Calcium; Capsid; Humans; In Vitro Techniques; Isoxazoles; Macromolecular Substances; Models, Molecular; Protein Conformation; Protein Structure, Quaternary; Rhinovirus; Thermodynamics

2001
Kinetics of thermal denaturation of human rhinoviruses in the presence of anti-viral capsid binders analyzed by capillary electrophoresis.
    Electrophoresis, 2002, Volume: 23, Issue:6

    Topics: Antiviral Agents; Benzoates; Capsid; Electrophoresis, Capillary; Heating; HeLa Cells; Humans; Isoelectric Point; Isoxazoles; Kinetics; Pyrroles; Rhinovirus; Temperature; Time Factors

2002
Motion of an antiviral compound in a rhinovirus capsid under rotational symmetry boundary conditions.
    Journal of molecular graphics & modelling, 2002, Volume: 21, Issue:1

    Topics: Antiviral Agents; Capsid; Computer Simulation; Isoxazoles; Models, Molecular; Rhinovirus; Water

2002
Virus-ligand interactions: identification and characterization of ligand binding by NMR spectroscopy.
    Journal of the American Chemical Society, 2003, Jan-08, Volume: 125, Issue:1

    Topics: Antiviral Agents; Binding Sites; Humans; Isoxazoles; Kinetics; Ligands; Nuclear Magnetic Resonance, Biomolecular; Rhinovirus; Substrate Specificity

2003
Human rhinovirus capsid dynamics is controlled by canyon flexibility.
    Virology, 2003, Sep-15, Volume: 314, Issue:1

    Topics: Antibodies, Viral; Antigen-Antibody Reactions; Binding Sites; Capsid; HeLa Cells; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Microscopy, Electron; Models, Molecular; Mutation; Oxadiazoles; Oxazoles; Rhinovirus; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Virus Assembly

2003
Dissociation of an antiviral compound from the internal pocket of human rhinovirus 14 capsid.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, May-24, Volume: 102, Issue:21

    Topics: Antiviral Agents; Capsid Proteins; Computational Biology; Computer Simulation; Humans; Isoxazoles; Models, Molecular; Principal Component Analysis; Protein Conformation; Protein Subunits; Rhinovirus

2005
VP4 protein from human rhinovirus 14 is released by pressure and locked in the capsid by the antiviral compound WIN.
    Journal of molecular biology, 2007, Feb-09, Volume: 366, Issue:1

    Topics: Antiviral Agents; Capsid; Capsid Proteins; Dose-Response Relationship, Drug; Drug Interactions; HeLa Cells; Humans; Hydrostatic Pressure; Isoxazoles; Rhinovirus; Temperature; Urea; Virus Assembly

2007
Pocket factors are unlikely to play a major role in the life cycle of human rhinovirus.
    Journal of virology, 2007, Volume: 81, Issue:12

    Topics: Capsid; Humans; Isoxazoles; Lasers; Models, Molecular; Mutagenesis; Mutation; Protein Binding; Proteins; Rhinovirus; RNA, Viral; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Time Factors; Transfection

2007