welwitindolinone-a and tropone

welwitindolinone-a has been researched along with tropone* in 1 studies

Other Studies

1 other study(ies) available for welwitindolinone-a and tropone

ArticleYear
Access to a welwitindolinone core using sequential cycloadditions.
    Organic letters, 2009, Aug-20, Volume: 11, Issue:16

    A concise approach to the core skeleton of the welwitindolinone alkaloids was developed on the basis of sequential cycloaddition reactions. First, a palladium catalyzed enantioselective [6 + 3] trimethylenemethane cycloaddition onto a tropone nucleus was used to generate the requisite bicyclo[4.3.1]decadiene. Subsequent modifications to the cycloadduct allowed for an intramolecular [4 + 2] cycloaddition to generate the oxindole and complete the core of the natural product family.

    Topics: Alkaloids; Cyclization; Indole Alkaloids; Indoles; Molecular Structure; Nitriles; Oxindoles; Palladium; Tropolone

2009