welwitindolinone-a has been researched along with tropone* in 1 studies
1 other study(ies) available for welwitindolinone-a and tropone
Article | Year |
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Access to a welwitindolinone core using sequential cycloadditions.
A concise approach to the core skeleton of the welwitindolinone alkaloids was developed on the basis of sequential cycloaddition reactions. First, a palladium catalyzed enantioselective [6 + 3] trimethylenemethane cycloaddition onto a tropone nucleus was used to generate the requisite bicyclo[4.3.1]decadiene. Subsequent modifications to the cycloadduct allowed for an intramolecular [4 + 2] cycloaddition to generate the oxindole and complete the core of the natural product family. Topics: Alkaloids; Cyclization; Indole Alkaloids; Indoles; Molecular Structure; Nitriles; Oxindoles; Palladium; Tropolone | 2009 |