Page last updated: 2024-08-24

web 2086 and thiazoles

web 2086 has been researched along with thiazoles in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's27 (90.00)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turner, NC; Wood, LJ1
Lohmeyer, M; Workman, P1
Binnaka, T; Fujimura, K; Inoue, K; Kitagawa, S; Kubota, Y; Mizuno, T; Tani, K; Yamaguchi, T1
Lewis, SA; Raeburn, D; Underwood, SL1
Cavero, I; Floch, A; Sedivy, P; Tahraoui, L1
Bernat, A; Gigo, V; Herbert, JM; Lale, A; LaPlace, MC; Le Fur, G; Lespy, L; Maffrand, JP; Savi, P; Valette, G1
Hara, H; Mase, T; Murase, K; Nagaoka, H; Saito, M; Tomioka, K; Yamada, T1
Gilfillan, AM; Hope, WC; Patel, BJ; Welton, AF; Wiggan, GA1
Herbert, JM; Lespy, L; Maffrand, JP1
Braquet, P; Ferreira, MG; Fonteles, MC1
Hirafuji, M; Shinoda, H1
Horie, M; Mase, T; Nagaoka, H; Sakurai, Y; Tomioka, K; Yamada, T1
Bloom, JW; Gomez, J; Halonen, M; Yamamura, HI1
Bazill, GW; Dexter, TM1
Bozza, PT; Cordeiro, RS; Dias, PM; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Vargaftig, BB1
Barnes, PJ; Birke, FW; Dent, G; Robaut, C; Sybrecht, GW; Ukena, D1
Araújo, CV; Barbosa-Filho, JM; Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Moreira, S; Thomas, G; Tibiriçá, EV1
Imanishi, N; Koike, H; Morooka, S; Natsume, Y1
Asakura, K; Narita, S1
Bird, IN; Daniels, RH; Elmore, MA; Finnen, MJ; Hill, ME1
Bachy, A; Fraisse, L; Herbert, JM; Keane, PE; Lale, A; Laplace, MC; Lassalle, J; Roche, B; Savi, P; Valette, G1
Gay, JC1
Bourdon, V; Damas, J; Remacle-Volon, G1
Giudice, A; Herbert, JM; Le Fur, G; Maffrand, JP; Manara, L; Manzoni, L1
Chignard, M; Paulin, D; Renesto, P; Vicart, P1
Chen, J; Giris, N1
Akiyama, M; Ino, M; Miwa, M; Shimura, M; Sugatani, J; Suzuki, M; Suzuki, Y; Yamazaki, R1
Bruyneel, E; Chastre, E; Gespach, C; Kotelevets, L; Mareel, M; Myssiakine, E; Noë, V1
Dy, LC; Pei, Y; Travers, JB1
Berthou, C; Bourge, JF; Denizot, Y; Geromin, D; Sasportes, M; Sigaux, F; Soulié, A; Zhang, Y1

Other Studies

30 other study(ies) available for web 2086 and thiazoles

ArticleYear
Characterization of the antagonist activity of the PAF antagonists RP 59227 and WEB 2086 on elicited guinea pig peritoneal macrophages. Evidence for variable affinities and kinetics.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Animals; Azepines; Guinea Pigs; Humans; Kinetics; Macrophages; Male; Neutrophils; Peritoneum; Platelet Activating Factor; Pyridines; Superoxides; Thiazoles; Triazoles

1992
Lack of enantio-selectivity in the in vitro antitumour cytotoxicity and membrane-damaging activity of ether lipid SRI 62-834: further evidence for a non-receptor-mediated mechanism of action.
    Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4

    Topics: Antineoplastic Agents; Azepines; Cell Death; Cell Membrane; Furans; Humans; Phospholipid Ethers; Platelet Aggregation Inhibitors; Stereoisomerism; Tetrazolium Salts; Thiazoles; Triazoles; Tumor Cells, Cultured

1992
Burn-induced gastric mucosal hemodynamic disturbance in the rat. Role of platelet-activating factor.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Burns; Gastric Mucosa; Hemodynamics; Hemoglobins; Male; Oxygen; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Regional Blood Flow; Thiazoles; Thiazolidines; Triazoles

1992
RP 59227, a novel PAF receptor antagonist: effects in guinea pig models of airway hyperreactivity.
    European journal of pharmacology, 1992, Jan-07, Volume: 210, Issue:1

    Topics: Animals; Antigens; Azepines; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridines; Thiazoles; Triazoles

1992
The platelet activating factor receptor antagonist, RP 59227, blocks platelet activating factor receptors mediating liberation of reactive oxygen species in guinea pig macrophages and human polymorphonuclear leukocytes.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2

    Topics: Animals; Azepines; Glyceryl Ethers; Guinea Pigs; Humans; Luminescent Measurements; Macrophages; Male; Neutrophils; Oxygen; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles

1991
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Azepines; Blood Platelets; Bronchoconstriction; Guinea Pigs; Humans; Injections, Intravenous; Leukopenia; Male; Mice; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thrombocytopenia; Triazoles

1991
Pharmacological properties of YM461, a new orally active platelet-activating factor antagonist.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Administration, Oral; Animals; Azepines; Blood Platelets; Blood Pressure; Cell Membrane; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles

1991
Ro 19-3704 directly inhibits immunoglobulin E-dependent mediator release by a mechanism independent of its platelet-activating factor antagonist properties.
    European journal of pharmacology, 1990, Feb-13, Volume: 176, Issue:3

    Topics: Animals; Azepines; Diterpenes; Ginkgolides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Inositol Phosphates; L-Lactate Dehydrogenase; Lactones; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Substance P; Synovial Fluid; Thiazoles; Triazines; Triazoles; Tumor Cells, Cultured

1990
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
    European journal of pharmacology, 1991, Dec-03, Volume: 205, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles

1991
Effects of PAF antagonists on renal vascular escape and tachyphylaxis in perfused rabbit kidney.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Azepines; Diterpenes; Female; Gangliosides; Ginkgolides; In Vitro Techniques; Kidney; Kinetics; Lactones; Male; Perfusion; Platelet Activating Factor; Pyridines; Rabbits; Renal Circulation; Tachyphylaxis; Thiazoles; Time Factors; Triazoles

1991
Platelet-leukocyte interaction in adhesion to endothelial cells induced by platelet-activating factor in vitro.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Adenine; Animals; Azepines; Blood Platelets; Cell Adhesion; Diterpenes; Endothelium, Vascular; Female; Ginkgolides; Humans; In Vitro Techniques; Lactones; Leukocytes; Neutrophils; Platelet Activating Factor; Platelet Adhesiveness; Pregnancy; Rabbits; Thiazoles; Triazoles; Umbilical Veins

1991
Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat.
    Biochemical and biophysical research communications, 1991, Apr-30, Volume: 176, Issue:2

    Topics: Animals; Azepines; Disease Models, Animal; Glomerulonephritis, Membranous; Hypercholesterolemia; Male; Metabolic Clearance Rate; Methylprednisolone; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Ticlopidine; Triazoles

1991
Characterization of receptors for platelet-activating factor in guinea pig lung membranes.
    American journal of respiratory cell and molecular biology, 1990, Volume: 3, Issue:3

    Topics: Animals; Azepines; Cell Membrane; Female; Guinea Pigs; Kinetics; Lung; Male; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles

1990
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil

1990
Pharmacological modulation of Paf-induced rat pleurisy and its role in inflammation by zymosan.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Animals; Azepines; Carrageenan; Leukocyte Count; Male; Platelet Activating Factor; Pleurisy; Pyridines; Rats; Rats, Inbred Strains; Thiazoles; Triazines; Triazoles; Zymosan

1989
Radioligand binding of antagonists of platelet-activating factor to intact human platelets.
    FEBS letters, 1988, Feb-15, Volume: 228, Issue:2

    Topics: Azepines; Binding Sites; Binding, Competitive; Blood Platelets; Humans; Kinetics; Platelet Activating Factor; Pyridines; Thiazoles; Triazines; Triazoles; Tritium

1988
Yangambin: a new naturally-occurring platelet-activating factor receptor antagonist: in vivo pharmacological studies.
    Planta medica, 1995, Volume: 61, Issue:2

    Topics: Animals; Antihypertensive Agents; Azepines; Blood Platelets; Female; Furans; Heart Rate; Leukocytes; Lignans; Male; Plants; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles

1995
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
    European journal of pharmacology, 1994, Nov-15, Volume: 269, Issue:3

    Topics: Animals; Azepines; Binding, Competitive; Calcium; Cell Count; Cell Degranulation; Chemotaxis, Leukocyte; Free Radical Scavengers; Inositol 1,4,5-Trisphosphate; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Standards; Signal Transduction; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines; Triazoles; Vitamin E

1994
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
    Auris, nasus, larynx, 1993, Volume: 20, Issue:3

    Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles

1993
Endothelial cell-associated platelet-activating factor primes neutrophils for enhanced superoxide production and arachidonic acid release during adhesion to but not transmigration across IL-1 beta-treated endothelial monolayers.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Oct-15, Volume: 153, Issue:8

    Topics: Arachidonic Acid; Azepines; Cell Adhesion; Cell Movement; Cell Polarity; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-1; Neutrophil Activation; Neutrophils; Piperazines; Platelet Activating Factor; Superoxides; Thiazoles; Thiazolidines; Triazoles

1994
Biochemical and pharmacological properties of SR 27388, a dual antioxidant and PAF receptor antagonist.
    Journal of lipid mediators, 1993, Volume: 8, Issue:1

    Topics: Animals; Antioxidants; Azepines; Blood Glucose; Blood Platelets; Cattle; Diabetes Mellitus, Experimental; Free Radical Scavengers; Humans; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Mitochondria, Heart; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Superoxides; Sympathomimetics; Thiazoles; Thiobarbituric Acid Reactive Substances; Triazoles

1993
Mechanism and regulation of neutrophil priming by platelet-activating factor.
    Journal of cellular physiology, 1993, Volume: 156, Issue:1

    Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella

1993
Platelet-activating factor and the vascular effects of zymosan in rats.
    European journal of pharmacology, 1993, Feb-09, Volume: 231, Issue:2

    Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Female; Hematocrit; Hemodynamics; Iodine Radioisotopes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Triazoles; Zymosan

1993
Prevention of platelet-activating factor-induced gastrointestinal lesions in rats by the new specific antagonist N-(2-dimethylaminoethyl)-N-(3-pyridinylmethyl)[4-(2,4,6-triisopropylphe nyl) thiazol-2yl]amine.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:4

    Topics: Animals; Azepines; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Diseases; Intestinal Mucosa; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Thiazoles; Triazoles

1996
Protective effect of platelet activating factor antagonists on cultured endothelial cell lysis induced by elastase or activated neutrophils.
    British journal of pharmacology, 1996, Volume: 117, Issue:5

    Topics: Azepines; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginkgolides; Humans; Lactones; Leukocyte Elastase; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles

1996
Species differences in PAF receptor binding in the lungs between hamster and guinea pig.
    Journal of lipid mediators and cell signalling, 1997, Volume: 16, Issue:2

    Topics: Animals; Azepines; Binding, Competitive; Cricetinae; Fibrinolytic Agents; Guinea Pigs; Kinetics; Ligands; Lung; Male; Mesocricetus; Organophosphorus Compounds; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Species Specificity; Thiazoles; Triazoles

1997
Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Neutrophils; P-Selectin; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles

1998
Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.
    The Journal of biological chemistry, 1998, Jun-05, Volume: 273, Issue:23

    Topics: Androstadienes; Animals; Azepines; Cell Adhesion Molecules; Cell Movement; Chromones; Colonic Neoplasms; Dogs; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, src; GTP-Binding Proteins; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Kidney; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Thiazoles; Transformation, Genetic; Triazoles; Tumor Cells, Cultured; Virulence Factors, Bordetella; Wortmannin

1998
Augmentation of ultraviolet B radiation-induced tumor necrosis factor production by the epidermal platelet-activating factor receptor.
    The Journal of biological chemistry, 1999, Sep-17, Volume: 274, Issue:38

    Topics: Azepines; Cells, Cultured; Humans; Indoles; Keratinocytes; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Thiazoles; Triazoles; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Vitamin E

1999
Interferon-gamma-induced membrane PAF-receptor expression confers tumor cell susceptibility to NK perforin-dependent lysis.
    Blood, 2000, Apr-01, Volume: 95, Issue:7

    Topics: Adult; Azepines; Calcium; Cell Membrane; Cytotoxicity, Immunologic; Gene Expression; Humans; Interferon-gamma; Killer Cells, Natural; Membrane Glycoproteins; Neoplasms; Perforin; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pore Forming Cytotoxic Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Transfection; Triazoles; Tumor Cells, Cultured

2000