Page last updated: 2024-08-24

web 2086 and n-formylmethionine leucyl-phenylalanine

web 2086 has been researched along with n-formylmethionine leucyl-phenylalanine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's20 (83.33)18.2507
2000's1 (4.17)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carolan, EJ; Casale, TB1
Müller, S; Nigam, S1
Bewtra, AK; Hopp, RJ; Miyagawa, H; Nabe, M; Okada, C; Townley, G1
Caramelo, C; Egido, J; Escanero, J; Gómez-Garre, D; González, E; Guerra, M; López-Farré, A; Riesco, A1
Javors, MA; Olson, MS; Zhou, W1
Alison, MR; Antoniw, JW; Garvey, B; Maseri, A; Tippins, JR1
Hirafuji, M; Shinoda, H1
Harris, T; Stewart, AG1
Barnes, PJ; Giembycz, MA; Kroegel, C1
Håkansson, L; Venge, P1
Bassot, S; Chignard, M; Ferrer-Lopez, P; Laurent, P; Renesto, P; Schattner, M1
Phillips, WA; Stewart, AG1
Fortes, ZB; Garcia-Leme, J; Lagente, V; Vargaftig, BB1
Bratt, J; Lerner, R; Palmblad, J; Ringertz, B1
Eskafi, S; Müller, S; Nigam, S; Zhang, H1
Imanishi, N; Koike, H; Morooka, S; Natsume, Y1
Gay, JC1
Pinckard, RN; Prihoda, TJ1
Hedqvist, P; Lindbom, L; Raud, J; Thorlacius, H; Xie, X1
Chilvers, ER; Condliffe, AM; Haslett, C; Kitchen, E; Rossi, AG1
Kohno, S; Nabe, T; Yamamura, H1
Berend, N; Matheson, MJ; McClean, MA; Rynell, AC1
Grandel, U; Grimminger, F; Hattar, K; Hoffmann, S; Mayer, K; Schenkel, A; Seeger, W; Sibelius, U1
Hecker, M; Mayer, K; Morty, RE; Schaefer, CA; Schaefer, MB; Seeger, W; Witzenrath, M1

Other Studies

24 other study(ies) available for web 2086 and n-formylmethionine leucyl-phenylalanine

ArticleYear
Effects of nedocromil sodium and WEB 2086 on chemoattractant-stimulated neutrophil migration through cellular and noncellular barriers.
    Annals of allergy, 1992, Volume: 69, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azepines; Cells, Cultured; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Nedocromil; Neutrophils; Platelet Activating Factor; Quinolones; Triazoles

1992
Enhancement by staurosporine of platelet-activating factor formation in N-formyl peptide-challenged human neutrophils is mediated by intracellular platelet-activating factor binding sites.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Alkaloids; Azepines; Binding Sites; Calcium; Drug Synergism; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles

1992
The effect of WEB 2086 on PAF-induced eosinophil chemotaxis and LTC4 production from eosinophils.
    Agents and actions, 1992, Volume: 37, Issue:1-2

    Topics: Adult; Asthma; Azepines; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Eosinophils; Female; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; SRS-A; Triazoles

1992
Aggregation of human polymorphonuclear leukocytes by endothelin: role of platelet-activating factor.
    European journal of pharmacology, 1992, Dec-02, Volume: 224, Issue:2-3

    Topics: Azepines; Calcium; Cell Aggregation; Centrifugation, Density Gradient; Cytosol; Diterpenes; Dose-Response Relationship, Drug; Endothelins; Ginkgolides; Humans; Lactones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Triazoles

1992
Platelet-activating factor as an intercellular signal in neutrophil-dependent platelet activation.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Sep-01, Volume: 149, Issue:5

    Topics: Amino Acid Sequence; Animals; Azepines; Blood Platelets; Cells, Cultured; Fibrinogen; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Signal Transduction; Thromboxane A2; Triazoles

1992
WEB 2086 inhibits neutrophil dependent increases in coronary resistance in blood perfused rabbit heart.
    Cardiovascular research, 1992, Volume: 26, Issue:2

    Topics: Animals; Azepines; Disease Models, Animal; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Triazoles; Vascular Resistance

1992
PAF-mediated platelet adhesion to endothelial cells induced by FMLP-stimulated leukocytes.
    Journal of lipid mediators, 1991, Volume: 4, Issue:3

    Topics: Azepines; Endothelium, Vascular; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Adhesiveness; Triazoles; Umbilical Veins

1991
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.
    Lipids, 1991, Volume: 26, Issue:12

    Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles

1991
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
    Journal of immunology (Baltimore, Md. : 1950), 1990, May-01, Volume: 144, Issue:9

    Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles

1990
Inhibition of neutrophil and eosinophil chemotactic responses to PAF by the PAF-antagonists WEB-2086, L-652,731, and SRI-63441.
    Journal of leukocyte biology, 1990, Volume: 47, Issue:5

    Topics: Azepines; Chemotaxis; Complement C5; Eosinophils; Furans; Humans; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Quinolinium Compounds; Triazoles

1990
Activation of human platelets by C5a-stimulated neutrophils: a role for cathepsin G.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 1

    Topics: Amino Acid Sequence; Aspirin; Azepines; Blood Platelets; Cathepsin G; Cathepsins; Complement C5a; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pancreatic Elastase; Platelet Activating Factor; Platelet Activation; Protease Inhibitors; Recombinant Proteins; Serine Endopeptidases; Serotonin; Triazoles

1990
Intracellular platelet-activating factor regulates eicosanoid generation in guinea-pig resident peritoneal macrophages.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Azepines; Calcimycin; Chromatography, High Pressure Liquid; Culture Media; Dinoprostone; Eicosanoids; Guinea Pigs; In Vitro Techniques; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Platelet Activating Factor; Superoxides; Triazines; Triazoles

1989
PAF-acether and endotoxin display similar effects on rat mesenteric microvessels: inhibition by specific antagonists.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Diterpenes; Endotoxins; Ginkgolides; Lactones; Male; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Splanchnic Circulation; Triazines; Triazoles

1988
Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Azepines; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Triazoles; Umbilical Veins; Virulence Factors, Bordetella

1995
Evidence for the predominant role of intracellular PAF binding sites in the regulation of phospholipase A2 in human neutrophils.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Alkaloids; Azepines; Humans; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Triazoles

1995
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
    European journal of pharmacology, 1994, Nov-15, Volume: 269, Issue:3

    Topics: Animals; Azepines; Binding, Competitive; Calcium; Cell Count; Cell Degranulation; Chemotaxis, Leukocyte; Free Radical Scavengers; Inositol 1,4,5-Trisphosphate; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Standards; Signal Transduction; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines; Triazoles; Vitamin E

1994
Mechanism and regulation of neutrophil priming by platelet-activating factor.
    Journal of cellular physiology, 1993, Volume: 156, Issue:1

    Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella

1993
Alkyl-PAF and acyl-PAF human neutrophil priming for enhanced fMLP- and rC5a-induced superoxide anion production.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:2

    Topics: Adrenergic beta-Antagonists; Amino Acid Sequence; Anions; Azepines; Complement C5a; Drug Synergism; Female; Humans; Male; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphatidylcholines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Recombinant Proteins; Superoxides; Triazoles

1996
Microvascular mechanisms of histamine-induced potentiation of leukocyte adhesion evoked by chemoattractants.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Amino Acid Sequence; Animals; Azepines; Chemotactic Factors; Drug Synergism; Female; Histamine; Leukocytes; Leukotriene B4; Microcirculation; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Rats, Wistar; Splanchnic Circulation; Triazoles

1995
Demonstration of reversible priming of human neutrophils using platelet-activating factor.
    Blood, 1996, Dec-01, Volume: 88, Issue:11

    Topics: Adult; Azepines; Cell Adhesion; Cell Polarity; Cell Size; Cells, Cultured; Dihydropyridines; Enzyme Activation; Humans; Imidazoles; Macrophage-1 Antigen; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Burst; Superoxides; Time Factors; Triazoles; Tumor Necrosis Factor-alpha

1996
Eosinophil chemotaxis induced by several biologically active substances and the effects of apafant on it in vitro.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:10

    Topics: Animals; Azepines; Bronchoalveolar Lavage Fluid; Chemotaxis; Eosinophils; Guinea Pigs; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Aggregation Inhibitors; Triazoles

1997
Role of platelet activating factor, leukotrienes and polymorphs in the FMLP induced increase in microvascular leakage in rabbit trachea.
    Respirology (Carlton, Vic.), 1997, Volume: 2, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkylating Agents; Animals; Azepines; Bronchitis; Capillary Permeability; Coloring Agents; Disease Models, Animal; Drug Interactions; Evans Blue; Indazoles; Leukotrienes; Male; Mechlorethamine; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rabbits; Reference Values; Trachea; Triazoles; Vasoconstrictor Agents

1997
Distinct pathways of lipopolysaccharide priming of human neutrophil respiratory burst: role of lipid mediator synthesis and sensitivity to interleukin-10.
    Critical care medicine, 2002, Volume: 30, Issue:10

    Topics: Arachidonic Acid; Autocrine Communication; Azepines; Escherichia coli; Humans; In Vitro Techniques; Indoles; Interleukin-10; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipopolysaccharide Receptors; Lipopolysaccharides; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Prospective Studies; Respiratory Burst; Superoxides; Triazoles

2002
Co-incubation of PMN and CaCo-2 cells modulates inflammatory potential.
    Cellular and molecular biology (Noisy-le-Grand, France), 2017, May-20, Volume: 63, Issue:5

    Topics: Aspirin; Azepines; Caco-2 Cells; Calcimycin; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; omega-N-Methylarginine; Pancreatic Elastase; Respiratory Burst; Triazoles

2017