Compounds > web 2086

Page last updated: 2024-08-24

web 2086 and bepafant

web 2086 has been researched along with bepafant in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (87.50)	18.2507
2000's	2 (12.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bures, MG; Carrera, GM; Davidsen, SK; Guinn, DE; Heyman, HR; May, PD; Phillips, JG; Pireh, D; Sheppard, GS; Steinman, DH	1
Bienvenu, K; Granger, DN; Russell, J	1
Heuer, HO; Muacevic, G	1
Ernst, A; Heuer, HO	1
Heuer, HO	2
Ono, S; Voelkel, NF	1
Neugarten, J; Schlondorff, D; Yoo, J	1
Casals-Stenzel, J; Heuer, HO	1
Cordeiro, RS; Fernandes, PD; Henriques, MG; Martins, MA; Silva, PM; Vargaftig, BB; Weg, VB	1
Andrews, MJ; Cunningham, FM; Foster, AP; Lees, P	1
Häyry, P; Mennander, A; Paavonen, T; Räisänen, A; Ustinov, J	1
Choy, PC; Hu, W; Man, RY; McNicholl, IK	1
Cunningham, FM; Foster, AP; Lees, P	1
Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM	1
Cellai, C; Laurenzana, A; Pancrazzi, A; Paoletti, F; Romanelli, MN; Vannucchi, AM	1

Reviews

2 review(s) available for web 2086 and bepafant

Article	Year
The effects of hetrazepine PAF antagonists in preclinical models of asthma. Agents and actions. Supplements, 1991, Volume: 34 Topics: Anaphylaxis; Animals; Antigens; Asthma; Azepines; Blood Platelets; Bronchi; Bronchoconstriction; Capillary Permeability; Cell Movement; Eosinophils; Lung; Platelet Activating Factor; Respiratory Hypersensitivity; Triazoles	1991
Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists. Lipids, 1991, Volume: 26, Issue:12 Topics: Animals; Azepines; Endotoxins; Humans; Models, Biological; Multiple Organ Failure; Platelet Activating Factor; Shock, Septic; Triazoles	1991

Other Studies

14 other study(ies) available for web 2086 and bepafant

Article	Year
3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists. Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13 Topics: Administration, Oral; Animals; Capillary Permeability; Edema; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Male; Mice; Platelet Activating Factor; Rabbits; Rats; Rats, Sprague-Dawley; Serotonin; Skin; Stereoisomerism; Structure-Activity Relationship; Thiazoles	1994
Leukotriene B4 mediates shear rate-dependent leukocyte adhesion in mesenteric venules. Circulation research, 1992, Volume: 71, Issue:4 Topics: Animals; Antigens, CD; Azepines; Benzopyrans; Cats; CD18 Antigens; Endothelium, Vascular; Indoles; Leukocytes; Leukotriene B4; Mesenteric Veins; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Triazoles; Venules	1992
Platelet-activating factor antagonists in experimental shock. Arzneimittel-Forschung, 1992, Volume: 42, Issue:8 Topics: Acid-Base Equilibrium; Animals; Azepines; Blood Pressure; Electrocardiography; Endotoxins; Hyperkalemia; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Shock; Triazoles	1992
PAF receptor antagonists influence asphyxia-induced changes of the inner ear. Journal of lipid mediators, 1991, Volume: 4, Issue:3 Topics: Animals; Asphyxia; Azepines; Cochlea; Electrophysiology; Female; Guinea Pigs; Kinetics; Male; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles	1991
PAF antagonists inhibit monocrotaline-induced lung injury and pulmonary hypertension. Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:6 Topics: Animals; Azepines; Cardiomegaly; Hypertension, Pulmonary; Lung; Lung Injury; Male; Monocrotaline; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles	1991
Protective effects of specific platelet-activating factor receptor antagonists in experimental glomerulonephritis. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3 Topics: Animals; Azepines; Glomerular Filtration Rate; Glomerulonephritis; Hemodynamics; Kidney; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles	1991
Use of WEB 2086 and WEB 2170 as platelet-activating factor antagonists. Methods in enzymology, 1990, Volume: 187 Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Lung; Methods; Molecular Structure; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Triazoles	1990
Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Carrageenan; Dose-Response Relationship, Drug; Edema; Exudates and Transudates; Female; Leukocyte Count; Male; Mice; Platelet Activating Factor; Pleurisy; Serotonin; Triazines; Triazoles	1990
A comparison of the actions of platelet activating factor (PAF) antagonists WEB 2170 and WEB 2086 in the horse. Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:4 Topics: Animals; Azepines; Capillary Permeability; Dose-Response Relationship, Drug; Histamine; Horses; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Skin; Triazoles	1993
Effect of platelet-activating factor (PAF) receptor blockers on smooth muscle cell replication in vitro and allograft arteriosclerosis in vivo. Transplant international : official journal of the European Society for Organ Transplantation, 1993, Volume: 6, Issue:5 Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Autoradiography; Azepines; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred WF; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Transplantation, Homologous; Triazoles	1993
Partial agonist effect of the platelet-activating factor receptor antagonists, WEB 2086 and WEB 2170, in the rat perfused heart. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: Animals; Azepines; Heart; In Vitro Techniques; Leukotrienes; Perfusion; Platelet Activating Factor; Platelet Membrane Glycoproteins; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Vasoconstriction; Vasodilation	1993
Actions of PAF receptor antagonists in horses with the allergic skin disease sweet itch. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:10 Topics: Animals; Azepines; Ceratopogonidae; Dermatitis, Allergic Contact; Edema; Female; Horse Diseases; Horses; Injections, Intradermal; Injections, Intravenous; Insect Bites and Stings; Male; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pruritus; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles	1995
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:7 Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured	2002
WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential. Leukemia, 2005, Volume: 19, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Azepines; Caspases; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Tretinoin; Triazoles	2005