way-151932 and lixivaptan

way-151932 has been researched along with lixivaptan* in 1 studies

Other Studies

1 other study(ies) available for way-151932 and lixivaptan

Article	Year
Identification and synthesis of major metabolites of Vasopressin V2-receptor agonist WAY-151932, and antagonist, Lixivaptan. Bioorganic & medicinal chemistry letters, 2007, Nov-01, Volume: 17, Issue:21 Small molecule agonists and antagonists of the V(2)-vasopressin receptor have been discovered and have undergone clinical trials. In conjunction with these discovery programs, the synthesis and biological testing of various metabolites associated with these clinical targets were actively pursued. We now report the results of our synthetic efforts and the corresponding biological data generated for several of the metabolites of WAY-151932 and CL-347985 (Lixivaptan). Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Humans; In Vitro Techniques; Pyrroles; Receptors, Vasopressin	2007

Article

Year

Identification and synthesis of major metabolites of Vasopressin V2-receptor agonist WAY-151932, and antagonist, Lixivaptan.

Bioorganic & medicinal chemistry letters, 2007, Nov-01, Volume: 17, Issue:21

Small molecule agonists and antagonists of the V(2)-vasopressin receptor have been discovered and have undergone clinical trials. In conjunction with these discovery programs, the synthesis and biological testing of various metabolites associated with these clinical targets were actively pursued. We now report the results of our synthetic efforts and the corresponding biological data generated for several of the metabolites of WAY-151932 and CL-347985 (Lixivaptan).

Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Humans; In Vitro Techniques; Pyrroles; Receptors, Vasopressin

2007