Page last updated: 2024-09-03

way 100135 and spiperone

way 100135 has been researched along with spiperone in 2 studies

Compound Research Comparison

Studies (way 100135)	Trials (way 100135)	Recent Studies (post-2010) (way 100135)	Studies (spiperone)	Trials (spiperone)	Recent Studies (post-2010) (spiperone)
143	0	34	2,944	13	85

Protein Interaction Comparison

Protein	Taxonomy	spiperone (IC50)
Bile salt export pump	Homo sapiens (human)	10
D(2) dopamine receptor	Homo sapiens (human)	0.0008
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
D(4) dopamine receptor	Homo sapiens (human)	0.0005
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
Histamine H1 receptor	Cavia porcellus (domestic guinea pig)	0.097
D(3) dopamine receptor	Homo sapiens (human)	0.0635
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	0.0001
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.955

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L	1
Escandon, NA; McCall, RB; Zimmermann, DC	1

Other Studies

2 other study(ies) available for way 100135 and spiperone

Article	Year
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists	1998
Characterization of the serotonin1A receptor antagonist activity of WAY-100135 and spiperone. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Membrane Potentials; Neurons; Piperazines; Serotonin Antagonists; Spiperone	1994

Article

Year

Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.

Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998

Characterization of the serotonin1A receptor antagonist activity of WAY-100135 and spiperone.

The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Membrane Potentials; Neurons; Piperazines; Serotonin Antagonists; Spiperone

1994