way 100135 has been researched along with scopolamine hydrobromide in 3 studies
| Studies (way 100135) | Trials (way 100135) | Recent Studies (post-2010) (way 100135) | Studies (scopolamine hydrobromide) | Trials (scopolamine hydrobromide) | Recent Studies (post-2010) (scopolamine hydrobromide) |
|---|---|---|---|---|---|
| 143 | 0 | 34 | 7,548 | 563 | 1,401 |
| Protein | Taxonomy | way 100135 (IC50) | scopolamine hydrobromide (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.003 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.006 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.0006 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carli, M; Luschi, R; Samanin, R | 1 |
| Pandya, AA; Yakel, JL | 1 |
| Blockx, I; Jonckers, E; Kara, F; Keliris, GA; Shah, D; Van der Linden, A; Verhoye, M | 1 |
3 other study(ies) available for way 100135 and scopolamine hydrobromide
| Article | Year |
|---|---|
(S)-WAY 100135, a 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine.
Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Hippocampus; Injections, Spinal; Learning; Male; Piperazines; Rats; Scopolamine; Serotonin Antagonists; Spatial Behavior; Time Factors | 1995 |
Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Drug Interactions; Isoxazoles; Learning; Male; Memory Disorders; Nicotinic Agonists; Nicotinic Antagonists; Phenylurea Compounds; Piperazines; Rats; Scopolamine; Serotonin 5-HT1 Receptor Antagonists | 2013 |
Cholinergic and serotonergic modulations differentially affect large-scale functional networks in the mouse brain.
Topics: Acetylcholine; Animals; Brain; Brain Mapping; Hypnotics and Sedatives; Magnetic Resonance Imaging; Male; Medetomidine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neural Pathways; Piperazines; Receptors, Muscarinic; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Antagonists | 2016 |