Compounds > way 100135
Page last updated: 2024-09-03

way 100135 and idazoxan

way 100135 has been researched along with idazoxan in 4 studies

Compound Research Comparison

Studies
(way 100135)		Trials
(way 100135)		Recent Studies (post-2010)
(way 100135)		Studies
(idazoxan)		Trials
(idazoxan)		Recent Studies (post-2010) (idazoxan)
1430341,49940123

Protein Interaction Comparison

ProteinTaxonomyway 100135 (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cervo, L; Rossi, C; Samanin, R; Tatarczynska, E1
Clarke, RW; Harris, J; Houghton, AK1
Aguerre, S; Chaouloff, F; Mormede, P1
Bornstein, JC; Foong, JP; Gwynne, RM; Parry, LJ1

Other Studies

4 other study(ies) available for way 100135 and idazoxan

ArticleYear
Role of 5-HT1A receptors in the antinociceptive action of 8-hydroxy-2-(di-n- propylamino)tetralin in the rat.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Injections, Subcutaneous; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists

1994
Spinal 5-HT-receptors and tonic modulation of transmission through a withdrawal reflex pathway in the decerebrated rabbit.
    British journal of pharmacology, 1996, Volume: 119, Issue:6

    Topics: Animals; Decerebrate State; Female; Idazoxan; Male; Ondansetron; Piperazines; Pyridines; Quinolines; Rabbits; Receptors, Serotonin; Reflex; Spinal Cord; Synaptic Transmission

1996
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
    Neuropharmacology, 1998, Volume: 37, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase

1998
5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Gene Expression; Guinea Pigs; Idazoxan; Ileum; Inhibitory Postsynaptic Potentials; Lysine; Male; Myenteric Plexus; Neurons; Norepinephrine; Oligopeptides; Piperazines; Quinolines; Receptor, Serotonin, 5-HT1A; Receptors, Somatostatin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists; Somatostatin; Submucous Plexus; Vasoactive Intestinal Peptide

2010