w 7 has been researched along with trifluoperazine in 260 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 141 (54.23) | 18.7374 |
| 1990's | 90 (34.62) | 18.2507 |
| 2000's | 21 (8.08) | 29.6817 |
| 2010's | 8 (3.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno, C; Carrieri, A; Cavalluzzi, MM; Franchini, C; Giannuzzi, G; Illario, M; Lentini, G; Lovece, A; Polimeno, L; Pracella, R; Rusciano, MR; Viale, M | 1 |
| Chung, CH; Ha, DB; Kang, MS; Kim, HS; Lee, IH | 1 |
| Mio, M; Tasaka, K; Yoshida, T | 1 |
| Nezu, E; Yoshimura, K | 1 |
| Dzwonczyk, S; Grover, GJ; Sargent, CA; Sleph, PG; Smith, MA | 1 |
| Silver, PJ; Stout, MA | 1 |
| Kennedy, AR; Umans, RS | 1 |
| Corvol, P; Della Bruna, R; Kurtz, A; Pinet, F | 1 |
| Kitazumi, K; Tasaka, K | 1 |
| Chen, LC; Ito, A; Mori, Y; Nagase, H; Ojima, Y; Sato, T | 1 |
| Chafouleas, JG; Gehm, BD; Laquerre, S; McConnell, DG; Pepperl, DJ; Pinke, RM; Schultz, DA | 1 |
| Iwashita, M; Izumi, S; Makino, T; Nozawa, S; Saito, S; Sakamoto, S; Takeda, Y | 1 |
| Ito, A; Kishima, K; Kuno, T; Mukai, H; Tanaka, C | 1 |
| Ichikawa, M; Matsumoto, G; Urayama, M | 1 |
| Chadha, KC; Davis, FB; Davis, PJ; Lin, HY; Thacore, HR | 1 |
| Barrera-Saldaña, HA; Forsbach, G; Hernández, RP; Martínez-Campos, A | 1 |
| Deanin, GG; Oliver, JM; Wilson, BS | 1 |
| Celada, A; Maki, RA | 1 |
| Hamatani, Y; Inoue, M; Kimura, K; Ohta, M; Shiota, M; Sugano, T | 1 |
| Nakayama, Y; Senoo, Y; Sugawara, E; Teramoto, S | 1 |
| Ammon, HP; Anazodo, MI; Safayhi, H | 1 |
| Cohan, CS; Edelman, AM; Polak, KA; Wasley, JW | 1 |
| Chobanian, MC; Julin, CM | 1 |
| Henshaw, EC; Kumar, RV; Panniers, R; Wolfman, A | 1 |
| Aprille, JR; Dransfield, DT; Nosek, MT | 1 |
| Kihira, M; Matsuzawa, K; Tokuno, H; Tomita, T | 1 |
| Farrell, CF; Rest, RF | 1 |
| Manganel, M; Turner, RJ | 1 |
| Abe, M; Inoue, M; Morikawa, M; Tsuboi, M; Yamauchi, Y | 1 |
| Hall, PF; Papadopoulos, V; Widmaier, EP | 1 |
| Bungay, PJ; Griffin, M; Mireylees, SE; Smethurst, PA | 1 |
| Gabbay, RA; Lebovitz, HE; Siconolfi-Baez, L | 1 |
| Ohishi, K; Suzuki, T; Uchida, MK | 1 |
| Damsky, C; Hwang, F; Phillips, PD; Ross, AH; Vance, P | 1 |
| Buddecke, E; Filipovic, I | 2 |
| Columbo, M; Condorelli, M; Giugliano, R; Marone, G; Poto, S | 1 |
| Ogawa, N; Ono, H; Yokota, S | 1 |
| Ohno-Shosaku, T; Oiki, S; Okada, Y; Yada, T | 1 |
| Kleis-San Francisco, S; Schuetz, AW | 1 |
| Suko, J; Wyskovsky, W | 1 |
| Lugnier, C; Schaeffer, P; Stoclet, JC | 1 |
| Kanazawa, M; Matsumoto, Y; Okumura, K; Tojyo, Y | 1 |
| Ambudkar, IS; Baum, BJ; Horn, VJ | 1 |
| Ito, A; Mori, Y; Nagase, H; Ojima, Y | 1 |
| Brumley, LM; Wallace, RW | 1 |
| Imamura, N; Kurokawa, K; Nakajima, S; Ueda, M | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| March, M; Murray, TM; Rao, LG | 1 |
| Luck, W; Simmet, T | 1 |
| Gibson, A; Shaw, CR | 1 |
| Braun, ID; Hait, WN; Kennedy, KA; Lazo, JS; Meandzija, B | 1 |
| Iwashima, A; Yamanishi, K | 1 |
| Koch, P; Leidig, A; Nebel, U; Peters, T; Wermelskirchen, D; Wilffert, B; Wilhelm, D | 1 |
| Bright, EC; Colombani, PM; Hess, AD; Wells, M | 1 |
| Rossi, NF; Schrier, RW | 1 |
| Shakes, DC; Ward, S | 1 |
| Bregestosvski, PD; Serebryakov, VN; Stinnakre, J; Zamoyski, VL | 1 |
| Kurebayashi, N; Ogawa, Y | 1 |
| Ida, E; Onoue, K; Sakata, A; Tominaga, M | 1 |
| Hidaka, H; Inagaki, M; Nishikawa, M; Tanaka, T | 1 |
| Devenyi, ZJ; Holian, A; Jordan, MK; Nguyen, HV | 1 |
| Kurokawa, K; Takaichi, K | 1 |
| Iwashima, A; Kitagawa, K; Nishino, H; Ogiso, Y | 1 |
| Izumi, F; Koda, Y; Uezono, Y; Wada, A; Yanagihara, N | 1 |
| Araki, Y; Furukawa, T; Inoue, N; Iwasa, T; Kushiku, K; Miyamoto, E | 1 |
| Darszon, A; Guerrero, A | 1 |
| Bourguignon, LY; Majercik, MH | 1 |
| Bright, EC; Colombani, PM; Hess, AD; Monastyrskyj, O | 1 |
| Durkin, JP; Whitfield, JF | 1 |
| Kawai, A | 1 |
| Hashimoto, K; Murakami, K; Ota, Z | 1 |
| Tallant, EA; Wallace, RW | 1 |
| Mattern, J; Mia, AJ; Oakford, LX; Royce, R; Tarapoom, N; Yorio, T | 1 |
| Ishikawa, S; Kuzuya, T; Saito, T | 1 |
| Engerson, T; Jones, HP; Legendre, JL | 1 |
| Dillingham, MA; Dixon, BS; Kim, JK; Wilson, PD | 1 |
| Classen, M; Schepp, W; Schusdziarra, V; Steffen, B | 1 |
| Aono, T; Hidaka, H; Iwase, K; Masunaga, R; Nagasaka, A; Nakai, A; Ohtani, S; Ohyama, T; Shinoda, S; Tanaka, T | 1 |
| Bhakdi, S; Roka, L; Seeger, W; Suttorp, N; Zucker-Reimann, J | 1 |
| Almendral, J; Bravo, R; Burckhardt, J; Müller, R; Neuberg, M; Wallich, R | 1 |
| Claggett, CE; Levenbook, L; Munoz, ML; Weinbach, EC; Wieder, SC | 1 |
| Chang, JY; Fertel, RH; Lewis, MG; Olsen, RG | 1 |
| Hoffman, MD; Wright, CD | 1 |
| Iriyama, H; Kasugai, M; Kato, H; Kato, M; Ninagawa, T; Tomoda, Y | 1 |
| Gautvik, KM; Gordeladze, J; Haug, E; Sand, O; Sletholt, K | 1 |
| Onaya, T; Shibata, K; Takazawa, K | 1 |
| Kramar, D; Olson, DM; Smieja, Z | 1 |
| Ober, SS; Pardee, AB | 1 |
| Borosky, SA; Cooper, CW | 1 |
| Fujii, K; Fujiwara, M; Kumada, K; Mori, H; Morikawa, S; Taniguchi, S | 1 |
| Chapekar, MS; Glazer, RI; Hartman, KD; Knode, MC | 1 |
| Ahlijanian, MK; Cooper, DM | 1 |
| Amoss, MS; Kile, JP | 1 |
| Nakagawa, Y; Waku, K | 1 |
| Block, GD; Khalsa, SB | 1 |
| Akamatsu, Y; Amano, F; Kitagawa, T | 1 |
| Kohno, N; Saitoh, Y; Wada, T | 1 |
| Hirose, M; Kitamura, T; Miyazaki, A; Namihisa, T; Takeuchi, M; Tomono, M; Watanabe, S | 1 |
| Buddecke, E; Eckardt, H; Filipovic, I; Hasilik, A | 1 |
| Doi, A; Etoh, S; Hatase, O; Itano, T; Matsui, H; Nakahara, S; Nishio, H | 1 |
| Izawa, T; Komabayashi, T; Shinoda, S; Suda, K; Tsuboi, M | 1 |
| Furuya, A; Kamada, A; Nishihata, T; Suzuka, T | 1 |
| Barron, E; Marshall, RJ; Martorana, M; Winslow, E | 1 |
| Little, DK; Moreland, RS; Moreland, S | 1 |
| Fujita, T; Hirata, Y; Takata, S; Tomita, M | 1 |
| Jo, OD; Yanagawa, N | 2 |
| Davis, PJ; Kawauchi, R; Lee, TP; Macara, I; Mookerjee, BK; Venuti, J | 1 |
| Hashimoto, N; Ikeda, Y; Maruyama, T; Oka, H; Sugiyama, Y; Toda, G | 1 |
| Murakami, J | 1 |
| Niewenhuis, RJ; Prozialeck, WC | 1 |
| Gemba, M; Nakajima, M; Nakano, S; Ushijima, H | 1 |
| Schrier, RW; Schwertschlag, U; Wilson, P | 1 |
| Akiyama, K; Fujii, N; Matsushita, K; Sutoo, D | 1 |
| Dedman, JR; LeGrue, SJ; Turner, R; Weisbrodt, N | 1 |
| Matsumoto, Y; Tojyo, Y | 1 |
| Danks, JA; Larkins, RG; Prince, RL; Shaw, M; Taft, JL | 1 |
| Amoroso, S; Annunziato, L; Di Renzo, GF; Taglialatela, M | 1 |
| Fujita, T; Jinnai, K; Takahashi, K | 1 |
| Cooper, CL; Malik, KU; Shaffer, JE | 1 |
| Lutz, F; Roka, L; Seeger, W; Suttorp, N; Uhl, J | 1 |
| Kosaki, G; Mori, T; Nishibe, S; Ogawa, M | 1 |
| Mohri, T; Takadera, T | 1 |
| Anelli, G; Berruti, G; Camatini, M | 1 |
| Condeelis, J; Detmers, PA | 1 |
| Smolen, JE; Stoehr, SJ | 1 |
| Ashoori, F; Takai, A; Tomita, T | 1 |
| Cintron, C; Soong, HK | 2 |
| Akamatsu, Y; Kitagawa, T | 1 |
| Asano, M; Hidaka, H | 1 |
| DeRiemer, SA; Kaczmarek, LK; Schweitzer, B | 1 |
| Akiyama, K; Iimura, K; Sutoo, D | 1 |
| Izawa, T; Komabayashi, T; Nakamura, T; Nakano, K; Tsuboi, M | 1 |
| Hidaka, H; Inagaki, M | 1 |
| Badwey, JA; Curnutte, JT; Karnovsky, MJ; Karnovsky, ML; Robinson, JM | 1 |
| Hidaka, H; Itoh, H | 1 |
| Chia, GH; Harracksingh, C; Horwitz, SB; Orlow, S; Pifko-Hirst, S; Rosen, OM; Schneck, J; Sorbara, L; Speaker, M; Wilk, EW | 1 |
| Kudo, S; Nagao, S; Nozawa, Y | 1 |
| Ochs, DL; Reed, PW | 1 |
| Inagami, T; Kawamura, M | 1 |
| Columbo, M; Condorelli, M; Marone, G; Poto, S | 1 |
| Ashcroft, SJ; Christie, MR; Harrison, DE; Lord, JM | 1 |
| Korchak, HM; Smolen, JE; Weissmann, G | 1 |
| Smolen, JE; Weissmann, G | 1 |
| Sheaves, RM | 1 |
| Hidaka, H; Ohmura, T; Tanaka, T | 1 |
| Heldsinger, A; Kaveh, R; Vinik, A; Walker, W | 1 |
| Brown, BL; MacNeil, S; Munro, DS; Ollis, CA; Sharrard, RM; Tomlinson, S; Walker, SW | 1 |
| Hidaka, H; Shikano, K | 1 |
| Garofalo, RS; Gilligan, DM; Satir, BH | 1 |
| Fujiki, H; Iwashima, A; Kato, R; Nakadate, T; Nishino, H; Sugimura, T | 1 |
| Billah, MM; Siegel, MI | 1 |
| Bauer, M; Bhakdi, S; Seeger, W | 1 |
| Olsnes, S; Sandvig, K; Sundan, A | 1 |
| Columbo, M; Condorelli, M; Genovese, A; Giugliano, R; Marone, G; Poto, S | 1 |
| Hofmann, F; Zimmer, M | 1 |
| Fujii, S; Harada, N; Nakamura, H; Okamoto, M; Shirasaka, T | 1 |
| Kato, T; Okumura-Noji, K; Tanaka, R | 1 |
| Hidaka, H; Inagaki, M; Tanaka, T | 1 |
| Hickie, RA; Klaassen, DJ; Wei, JW | 1 |
| Levy, JV | 1 |
| Fugman, DA; Johnson, JD | 1 |
| Hofmann, F; Kreye, VA; Rüegg, JC | 1 |
| Cormier, MJ; Lenz, RW | 1 |
| Ito, J; Kato, T; Okumura, K; Tanaka, R | 1 |
| Deierkauf, M; Elferink, JG; Riemersma, JC | 1 |
| Brown, BL; Mac Neil, S; Tomlinson, S; Walker, SW | 1 |
| Alobaidi, T; Naccache, PH; Sha'afi, RI | 1 |
| Alobaidi, T; Becker, EL; Molski, TF; Naccache, PH; Sha'afi, RI; Showell, HJ | 1 |
| Kimura, J | 1 |
| Kleene, SJ | 1 |
| Naderali, EK; Poyser, NL | 2 |
| Choi, HK; Choi, SK; Chowdhury, S; Debnath, NC; Kadono-Okuda, K; Kato, Y; Miyanoshita, A; Taniai, K; Xu, J; Yamamoto, M | 1 |
| Gukovskaya, AS; Pandol, SJ | 1 |
| Matsumoto, T; Yamada, H | 1 |
| Abo-el-Saad, M; Wu, R | 1 |
| Abe, K; Igarashi, Y; Ito, O; Kondo, Y; Omata, K; Takahashi, N | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Goko, H; Matsuoka, A | 1 |
| Komatsu, M; McDermott, AM; Sharp, GW | 1 |
| Anthony, FA; Costlow, ME; Dowdy, JC | 1 |
| Bold, RJ; Ishizuka, J; Thompson, JC; Townsend, CM | 1 |
| Ning, YM; Sánchez, ER | 1 |
| Bernstein, H; Compans, RW; Oliver, C; Srinivas, RV | 1 |
| Chetkovich, DM; Sweatt, JD | 1 |
| Ashizawa, K; Tomonaga, H; Tsuzuki, Y | 1 |
| Bouzinba-Segard, H; Castagna, M; Fan, XT; Perderiset, M | 1 |
| Broad, S; Herget, T; Rozengurt, E | 1 |
| Carter, C; Nicolas, C | 1 |
| Shiraishi, N; Waalkes, MP | 1 |
| Kaburaki, H; Kurosaki, F; Nishi, A | 1 |
| Dunlop, J; Ennis, C; Minchin, MC; Rossiter, J | 1 |
| Duncan, G; Gandolfi, SA; Sanderson, J | 1 |
| Khan, NA; Moulinoux, JP; Quemener, V; Sezan, A | 1 |
| Fukuda, H; Katori, T; Kimura, S; Yasuda, H | 1 |
| Desmond, ME; Duzy, MJ; Federici, BD | 1 |
| Sitges, M; Talamo, BR | 1 |
| Barlow, JW; Kolliniatis, E; Scholz, GH; Stockigt, JR; Topliss, DJ | 1 |
| Abe, K; Higo, K; Matsuki, N; Nakazawa, K; Saito, H; Tanaka, Y | 1 |
| Delamere, NA; Kuwahara, S; Mito, T | 1 |
| Coraboeuf, E; Coulombe, A; Ghazi, A; Lefevre, T | 1 |
| He, LP; Kitasato, H | 1 |
| Keep, RF; Xiang, J | 1 |
| Maher, P; Oliver, I; Sinclair, W; Trewavas, A | 1 |
| De Graan, PN; De Wit, M; Gispen, WH; Hens, JJ; Marquart, A; Oestreicher, AB | 1 |
| Cinotti, GA; Menè, P; Pugliese, F | 1 |
| Eker, P; Garred, O; Holm, PK; Jacobsen, J; Llorente, A; Sandvig, K; van Deurs, B | 1 |
| García-Cardeña, G; Nathan, CF; Sessa, WC; Smith, SD; Weiss, RM; Wheeler, MA | 1 |
| Cherry, CA; Laver, DR; Walker, NA | 1 |
| Capuozzo, E; Crifò, C; Salerno, C; Verginelli, D | 1 |
| Fusetani, N; Matsumura, K; Nagano, M; Saikawa, W; Tachibana, A; Yamamoto, H | 1 |
| Ito, A; Mori, Y; Nagase, H; Sanekata, K; Sato, H; Sato, T; Seiki, M; Yamada, M | 1 |
| Ache, BW; Doolin, RE; Zhainazarov, AB | 1 |
| Moreland, RS; Rokolya, A; Singer, HA; Walsh, MP | 1 |
| Gerke, V; Kielbassa, K; Schmitz, C | 1 |
| Liebmann, PM; Schauenstein, K; Wölfler, A | 1 |
| Cioni, C; Colasanti, M; Fabrizi, C; Francia, N; Venturini, G | 1 |
| Bernal, RM; Muñoz, ML; Santos, JI; Tovar, R | 1 |
| Ikura, M; Osawa, M; Tomomori, C | 1 |
| Atwater, I; He, LP; Kitasato, H; Mears, D | 1 |
| Densmore, JJ; Gray, LS; Haverstick, DM | 1 |
| Hidaka, H; Ikura, M; Izumi, Y; Kuwamoto, S; Matsushima, N; Osawa, M; Shibanuma, T; Yap, KL; Yokokura, H | 1 |
| Daniel, H; Diehl, D; Herget, M; Kuntz, S; Wenzel, U | 1 |
| Benech, JC; Crispino, M; Giuditta, A; Kaplan, BB | 1 |
| Chen, J; Hoffman, BB; Hu, ZW; Lin, R | 1 |
| Gadea, A; López-Colomé, AM | 1 |
| Arias-Negrete, S; Muñoz, Mde L; Murillo-Jasso, F | 1 |
| Elmendorf, JS; Pessin, JE; Sacks, DB; Watson, RT; Yang, C | 1 |
| Hayashi, N; Izumi, Y; Jinbo, Y; Matsushima, N | 1 |
| Cacicedo, L; Franco, FS; Palacios, N; Tolón, R; Vicente, AB; Villuendas, G | 1 |
| Hara, A; Kusakari, J; Tabuchi, K; Tsuji, S | 1 |
| Fliegel, L; Moor, AN; Murtazina, R | 1 |
| Braiman, A; Gheber, L; Priel, Z; Zagoory, O | 1 |
| Goudeau, H; Goudeau, M | 1 |
| De Baetselier, P; De Braekeleer, J; Dewit, J; Grabski, R; Malicka-Blaskiewicz, M; Verschueren, H | 1 |
| Darszon, A; De La Vega-Beltrán, JL; Felix, R; Florman, HM; López-González, I; Santi, CM | 1 |
| Poovaiah, BW; Veluthambi, K | 1 |
| Basavappa, S; Chang, CB; Huang, CC; Lim, PH; Liu, JY | 1 |
| Del Carlo, B; Pellegrini, M; Pellegrino, M | 1 |
| Sampieri, A; Vaca, L | 1 |
| Fukushi, H; Morishima, Y; Shirasaki, Y; Takano, H | 1 |
| Blödow, A; Ernst, A; Kolb, HA; Ngezahayo, A | 1 |
| Feng, X; McDonald, JM; Zhang, L | 1 |
| Bootman, MD; Collins, TJ; Holmes, AM; McDonald, F; Peppiatt, CM; Roderick, HL; Seo, JT | 1 |
| Han, ES; Ko, HH; Lee, CS; Park, SY; Shin, YK; Song, JH | 1 |
| Chou, CL; Fenton, RA; Hoffert, JD; Knepper, MA | 1 |
| Biswal, B; Fujiki, Y; Furumoto, T; Ito, M; Nakagawa, Y; Nishida, I; Watanabe, A; Yoshida, S | 1 |
| Bang, H; Han, ES; Han, YS; Lee, CS | 1 |
| Ingermann, RL; Zuccarelli, MD | 1 |
| Honda, Y; Irie, T; Kitaura, H; Minami, M; Sakamoto, T; Suzuki, K; Ueda, A; Watanabe, T | 1 |
| Gupta, V; Roy, A; Tripathy, BC | 1 |
| Bai, VU; Barrack, ER; Chinnakannu, K; Kim, SH; Menon, M; Murthy, S; Reddy, GP; Sivanandam, A | 1 |
| Lübker, C; Lushington, GH; Richter, M; Schuler, D; Seifert, R; Shen, Y; Tang, WJ | 1 |
| Devi, BS; Khorolragchaa, A; Kim, YJ; Lee, OR; Parvin, S; Sathiyaraj, G; Yang, DC | 1 |
| Glass, P; Hoey, EM; McFerran, NV; Moore, CM; Russell, SL; Timson, DJ; Trudgett, A; Tsang, Y | 1 |
| Bedwell, GJ; Chen, Y; Fernandez, TF; Saad, JS; Samal, AB | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
4 review(s) available for w 7 and trifluoperazine
| Article | Year |
|---|---|
Protein phosphorylation in the pancreatic B-cell.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calmodulin; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Molecular Weight; Myosin-Light-Chain Kinase; Phosphoproteins; Protein Kinase C; Protein Kinases; Subcellular Fractions; Substrate Specificity; Sulfonamides; Trifluoperazine | 1984 |
Calmodulin: a multifunctional protein for the control of cellular activity and homeostasis. A review of its physico-chemical properties and pharmacological manipulation.
Topics: Animals; Calcium-Transporting ATPases; Calmodulin-Binding Proteins; Carrier Proteins; Enzyme Activation; Homeostasis; Insulin; Insulin Secretion; Muscle Contraction; Muscle, Smooth; Myosins; Phosphoric Diester Hydrolases; Phosphorylase Kinase; Phosphorylation; Rabbits; Rats; Sulfonamides; Trifluoperazine | 1982 |
[Overview on the research on calmodulin and its inhibitors].
Topics: Animals; Calcium; Calmodulin; Cell Cycle; Cells, Cultured; Chromatography, Affinity; Enzyme Activation; Humans; Phosphoric Diester Hydrolases; Platelet Aggregation; Protein Binding; Rats; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1983 |
[Calmodulin: the progress in three-dimensional structure analysis].
Topics: Animals; Calcium Signaling; Calcium-Binding Proteins; Calmodulin; Humans; Protein Conformation; Protein Engineering; Sulfonamides; Trifluoperazine | 1998 |
256 other study(ies) available for w 7 and trifluoperazine
| Article | Year |
|---|---|
The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cattle; Humans; Molecular Docking Simulation; Piperidines; Protein Conformation; Protein Kinase Inhibitors; Thiazoles | 2016 |
Ca2+/calmodulin-dependent phosphorylation of the 100-kDa protein in chick embryonic muscle cells in culture.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Differentiation; Cell Fusion; Cells, Cultured; Chick Embryo; Chlorpromazine; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Molecular Weight; Muscle Proteins; Muscles; Phosphoproteins; Phosphorylation; Protein Kinases; Sulfonamides; Trifluoperazine | 1992 |
Cortisol secretion induced by substance P from bovine adrenocortical cells and its inhibition by calmodulin inhibitors.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Calcium; Calmodulin; Cattle; Cyclic AMP; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; Neurokinin A; Neurokinin B; Signal Transduction; Substance P; Sulfonamides; Trifluoperazine | 1992 |
Interaction between the calcium and cyclic AMP messenger systems in perifused rat parotid acinar cells. Possible mechanism for potentiation of amylase secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Parotid Gland; Perfusion; Phorbol 12,13-Dibutyrate; Phosphorylation; Rats; Rats, Inbred Strains; Second Messenger Systems; Sulfonamides; Trifluoperazine | 1992 |
Effect of calmodulin and protein kinase C inhibitors on globally ischemic rat hearts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Animals; Benzimidazoles; Calmodulin; Coronary Disease; Heart; In Vitro Techniques; Isoquinolines; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Naphthalenes; Piperazines; Polycyclic Compounds; Polymyxin B; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Sulfonamides; Trifluoperazine | 1992 |
Calcium transport by sarcoplasmic reticulum of vascular smooth muscle: II. Effects of calmodulin and calmodulin inhibitors.
Topics: Actomyosin; Aluminum; Animals; Biological Transport, Active; Calcium; Calmodulin; Cells, Cultured; Imidazoles; Muscle, Smooth, Vascular; Oxalates; Oxalic Acid; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Sulfonamides; Trifluoperazine | 1992 |
Effects of activators and inhibitors of protein kinase C on X-ray induced malignant transformation in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antipain; Calcimycin; Cell Transformation, Neoplastic; Diglycerides; Enzyme Activation; Isoquinolines; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Piperazines; Protein Kinase C; Sulfonamides; Trifluoperazine; Trypsin Inhibitor, Bowman-Birk Soybean | 1992 |
Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro.
Topics: Animals; Calmodulin; Cells, Cultured; Cycloheximide; Imidazoles; Juxtaglomerular Apparatus; Kinetics; Male; Mice; Mice, Inbred C57BL; Protein Biosynthesis; Renin; Sulfonamides; Sulfur Radioisotopes; Trifluoperazine | 1992 |
Thrombin-stimulated phosphorylation of myosin light chain and its possible involvement in endothelin-1 secretion from porcine aortic endothelial cells.
Topics: Animals; Aorta; Azepines; Cells, Cultured; Endothelins; Endothelium, Vascular; Gallic Acid; Myosins; Phosphorylation; Protein Kinases; Sulfonamides; Swine; Thrombin; Trifluoperazine | 1992 |
Calmodulin differentially modulates the interleukin 1-induced biosynthesis of tissue inhibitor of metalloproteinases and matrix metalloproteinases in human uterine cervical fibroblasts.
Topics: Blotting, Northern; Blotting, Western; Calmodulin; Cervix Uteri; Connective Tissue; Extracellular Matrix; Female; Gene Expression; Glycoproteins; Humans; In Vitro Techniques; Interleukin-1; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Metalloendopeptidases; Microbial Collagenase; RNA, Messenger; Sulfonamides; Tissue Inhibitor of Metalloproteinases; Trifluoperazine | 1991 |
Activation of bovine rod outer segment phosphatidylinositol-4,5-bisphosphate phospholipase C by calmodulin antagonists does not depend on calmodulin.
Topics: Animals; Calmodulin; Cattle; Enzyme Activation; Haloperidol; Imidazoles; Kinetics; p-Methoxy-N-methylphenethylamine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Rod Cell Outer Segment; Substrate Specificity; Sulfonamides; Trifluoperazine; Type C Phospholipases | 1991 |
Phorbol ester-induced LH release in pituitary gonadotrophs: effects of antagonists of calmodulin and GnRH.
Topics: Animals; Calmodulin; Dose-Response Relationship, Drug; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland; Rats; Receptors, LHRH; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1991 |
Calmodulin antagonists differentiate between Ni(2+)- and Mn(2+)-stimulated phosphatase activity of calcineurin.
Topics: 4-Nitrophenylphosphatase; Animals; Brain; Calcineurin; Calmodulin; Calmodulin-Binding Proteins; Cattle; Imidazoles; Kinetics; Manganese; Nickel; Phosphoprotein Phosphatases; Sulfonamides; Thioridazine; Trifluoperazine | 1991 |
Anticalmodulin drugs block the sodium gating current of squid giant axons.
Topics: Animals; Axons; Biological Transport, Active; Calmodulin; Chlorpromazine; Decapodiformes; Diazepam; Imidazoles; Ion Channel Gating; Membrane Potentials; Phenothiazines; Potassium; Quinacrine; Sodium; Sulfonamides; Trifluoperazine | 1991 |
Effect of calmodulin antagonists on the interferon system: induction and action of interferons.
Topics: Animals; Calmodulin; Cells, Cultured; Humans; Interferon Inducers; Interferons; Parainfluenza Virus 1, Human; Sulfonamides; Trifluoperazine | 1990 |
The stimulatory effect of estradiol 17-beta on prolactin mRNA is inhibited by anti-calmodulin drugs.
Topics: Animals; Blotting, Northern; Calmodulin; Estradiol; Estrogen Antagonists; Male; Metoclopramide; Nucleic Acid Hybridization; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Sulfonamides; Trifluoperazine | 1991 |
Regulation of IgE receptor-mediated secretion from RBL-2H3 mast cells by GTP binding-proteins and calcium.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Calcium; Calmodulin; Cell Line; Cholera Toxin; GTP-Binding Proteins; Immunoglobulin E; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Mast Cells; Mycophenolic Acid; Rats; Receptors, Fc; Receptors, IgE; Serotonin; Sulfonamides; Terpenes; Thapsigargin; Trifluoperazine | 1991 |
IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Calcimycin; Calmodulin; Gene Expression Regulation; Histocompatibility Antigens Class II; Interferon-gamma; Ionomycin; Isoquinolines; Macrophages; Major Histocompatibility Complex; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase C; RNA, Messenger; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Tumor Necrosis Factor-alpha | 1991 |
Effects of calmodulin antagonists on hydrogen-translocating shuttles in perfused rat liver.
Topics: Adrenalectomy; Alanine; Aminooxyacetic Acid; Animals; Asparagine; Calcium; Calmodulin; Chlorpromazine; Glycerolphosphate Dehydrogenase; Hyperthyroidism; Hypothyroidism; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Perfusion; Propylthiouracil; Rats; Rats, Inbred Strains; Reference Values; Sorbitol; Sulfonamides; Thyroxine; Trifluoperazine; Triiodothyronine; Vasopressins | 1991 |
Protective effects of calmodulin antagonists (trifluoperazine and W-7) on hypothermic ischemic rat hearts.
Topics: Acetylglucosaminidase; Animals; Calmodulin; Cathepsin D; Coronary Disease; Creatine Kinase; Heart; Hypothermia; Lysosomes; Male; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1991 |
Calmodulin- and Ca2(+)-insensitive fatty acid methyltransferase from RINm5F cells. Inhibition by trifluoperazine and W7.
Topics: Animals; Benzimidazoles; Calcium; Calmodulin; Egtazic Acid; Hot Temperature; Insulinoma; Methylation; Methyltransferases; Pancreatic Neoplasms; Rats; S-Adenosylhomocysteine; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1991 |
A novel calmodulin antagonist, CGS 9343B, modulates calcium-dependent changes in neurite outgrowth and growth cone movements.
Topics: Animals; Axons; Benzimidazoles; Calcium; Calmodulin; Cell Movement; Electrophysiology; Neurons; Serotonin; Snails; Sulfonamides; Trifluoperazine | 1991 |
Angiotensin II stimulates ammoniagenesis in canine renal proximal tubule segments.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Acid-Base Equilibrium; Ammonia; Angiotensin II; Animals; Calcium; Calmodulin; Dogs; Dose-Response Relationship, Drug; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Sulfonamides; Trifluoperazine | 1991 |
Inhibition of protein synthesis by antagonists of calmodulin in Ehrlich ascites tumor cells.
Topics: Animals; Calmodulin; Carcinoma, Ehrlich Tumor; Cell-Free System; Centrifugation, Density Gradient; Imidazoles; Methionine; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Transfer; Sulfonamides; Sulfur Radioisotopes; Trifluoperazine | 1991 |
Calcium stimulates ATP-Mg/Pi carrier activity in rat liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium Chloride; Calmodulin; Carrier Proteins; Cells, Cultured; Chlorpromazine; Egtazic Acid; Glucagon; Imidazoles; Kinetics; Liver; Magnesium; Male; Mitochondria, Liver; Neomycin; Phosphates; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Vasopressins | 1990 |
Effects of calmodulin antagonists on calcium-activated potassium channels in pregnant rat myometrium.
Topics: Animals; Calcium; Calmodulin; Cytoplasm; Egtazic Acid; Electrophysiology; Female; Membrane Potentials; Myometrium; Potassium Channels; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1990 |
Up-regulation of human neutrophil receptors for Neisseria gonorrhoeae expressing PII outer membrane proteins.
Topics: Antibodies, Monoclonal; Antigens, Bacterial; Bacterial Adhesion; Calcium Channel Blockers; Calmodulin; Gallic Acid; Humans; Neisseria gonorrhoeae; Neutrophils; Pertussis Toxin; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Up-Regulation; Virulence Factors, Bordetella | 1990 |
Agonist-induced activation of Na+/H+ exchange in rat parotid acinar cells is dependent on calcium but not on protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Carbachol; Carrier Proteins; Diglycerides; Epinephrine; Isoquinolines; Male; Parotid Gland; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers; Sulfonamides; Trifluoperazine | 1990 |
Priming effect of 2,3-dibenzylbutane-1,4-diol (mammalian lignan) on superoxide production in human neutrophils.
Topics: Alkaloids; Benzyl Compounds; Calcimycin; Calcium; Cell Compartmentation; Diglycerides; Humans; In Vitro Techniques; Lignans; Lignin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Trifluoperazine | 1990 |
The role of calmodulin in the responses to adrenocorticotropin of plasma membranes from adrenal cells.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Calmodulin; Cell Membrane; Chlorpromazine; Colforsin; Cyclic AMP; Immunoglobulin G; Mice; Pimozide; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1990 |
Calmodulin involvement in Ca2(+)-induced insulin release from electropermeabilized islets of Langerhans.
Topics: Animals; Calcium; Calmodulin; Electric Stimulation; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Permeability; Rats; Sulfonamides; Trifluoperazine | 1990 |
Calcium-dependent protein kinase activity is decreased in diabetic rat sciatic nerve.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Chromatography, Gel; Diabetes Mellitus, Experimental; Diglycerides; Enzyme Activation; Isoquinolines; Male; Phosphatidylserines; Phospholipids; Piperazines; Polymyxin B; Protein Kinase C; Rats; Rats, Inbred Strains; Sciatic Nerve; Sulfonamides; Trifluoperazine | 1990 |
Relation between inhibition of calmodulin and mediator release from rat mast cells.
Topics: Animals; Calcium; Calmodulin; Chlorpromazine; Histamine Release; Lidocaine; Liposomes; Male; Mast Cells; Rats; Rats, Inbred Strains; Serotonin; Structure-Activity Relationship; Sulfonamides; Trifluoperazine | 1985 |
Inhibition of epidermal growth factor-induced phosphorylation by trifluoperazine.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Chlorpromazine; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Imipramine; Mice; Microscopy, Electron, Scanning; Phosphorylation; Phosphotyrosine; Receptors, Cell Surface; Sulfonamides; Trifluoperazine; Tyrosine | 1985 |
Calmodulin antagonists stimulate LDL receptor synthesis in human skin fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Acetic Acid; Androstenes; Calcium Chloride; Calmodulin; Cholera Toxin; Cholesterol; Cyclic AMP; Fibroblasts; Humans; Hydroxycholesterols; Lovastatin; Methionine; Mevalonic Acid; Molecular Weight; Naphthalenes; p-Methoxy-N-methylphenethylamine; Receptors, LDL; Skin; Sulfonamides; Trifluoperazine | 1986 |
Possible role of calmodulin in the control of histamine release from human basophil leukocytes.
Topics: Basophils; Calmodulin; Dose-Response Relationship, Drug; Histamine Release; Humans; Phenothiazines; Sulfonamides; Trifluoperazine | 1986 |
Inhibitory effects of trifluoperazine and chlorpromazine, calmodulin inhibitor, on autoregulation of renal blood flow.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Chloride; Calmodulin; Chlorpromazine; Dogs; Female; Homeostasis; Male; Renal Circulation; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1987 |
Evidence for the involvement of calmodulin in the operation of Ca-activated K channels in mouse fibroblasts.
Topics: Animals; Calcium; Calmodulin; Cations, Divalent; Intracellular Fluid; Ion Channels; L Cells; Membrane Potentials; Mice; Potassium; Promethazine; Sulfonamides; Trifluoperazine | 1987 |
Sources of calcium and the involvement of calmodulin during steroidogenesis and oocyte maturation in follicles of Rana pipiens.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calmodulin; Female; Gallic Acid; Imidazoles; Lanthanum; Oocytes; Ovarian Follicle; Progesterone; Rana pipiens; Sulfonamides; Trifluoperazine | 1987 |
Drug-induced calcium release from sarcoplasmic reticulum of skeletal muscle.
Topics: Animals; Calcium; Calmodulin; Imidazoles; In Vitro Techniques; Ion Channels; Kinetics; p-Methoxy-N-methylphenethylamine; Rabbits; Sarcoplasmic Reticulum; Sulfonamides; Trifluoperazine | 1988 |
Interaction of calmodulin and calcium antagonists with [3H]diltiazem and [3H]nitrendipine binding sites.
Topics: Animals; Bepridil; Calcium Channel Blockers; Calcium Channels; Calmodulin; Diltiazem; Imidazoles; Phosphodiesterase Inhibitors; Pyrrolidines; Rats; Receptors, Nicotinic; Sulfonamides; Trifluoperazine | 1988 |
The role of calmodulin in rat parotid amylase secretion: effects of calmodulin antagonists on secretion and acinar cell structure.
Topics: Amylases; Animals; Bucladesine; Calmodulin; Carbachol; Cells, Cultured; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Microscopy, Electron; Parotid Gland; Rats; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1989 |
ATP-dependent Ca2+ transport in the rat parotid basolateral plasma membrane is regulated by calmodulin.
Topics: Animals; Biological Transport, Active; Calcium; Calmodulin; Cell Membrane; Cell Membrane Permeability; Egtazic Acid; Imidazoles; In Vitro Techniques; Kinetics; Male; Parotid Gland; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1989 |
Calmodulin regulates the interleukin 1-induced procollagenase production in human uterine cervical fibroblasts.
Topics: Adult; Blotting, Western; Calmodulin; Cells, Cultured; Cervix Uteri; Collagenases; Enzyme Precursors; Female; Fibroblasts; Humans; Interleukin-1; Kinetics; Macrophages; Microbial Collagenase; Molecular Weight; Sulfonamides; Trifluoperazine | 1989 |
Calmodulin and protein kinase C antagonists also inhibit the Ca2+-dependent protein protease, calpain I.
Topics: Bee Venoms; Calmodulin; Calpain; Erythrocytes; Humans; Imidazoles; Kinetics; Melitten; Protein Kinase C; Sulfonamides; Trifluoperazine | 1989 |
A study on the hypotensive mechanism of pinacidil: relationship between its vasodilating effect and intracellular Ca2+ levels.
Topics: Animals; Antihypertensive Agents; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Hydralazine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Pinacidil; Rabbits; Sulfonamides; Trifluoperazine; Vasodilation | 1989 |
Vascular endothelial cell migration in vitro roles of cyclic nucleotides, calcium ion and cytoskeletal system.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Bucladesine; Calcium Channel Blockers; Cattle; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin B; Diltiazem; Endothelium, Vascular; Fetus; Gallic Acid; Nicardipine; Sulfonamides; Theophylline; Trifluoperazine | 1989 |
Calcium modulation of the parathyroid hormone-sensitive adenylate cyclase in ROS 17/2.8 cells: effects of N-(6-aminohexyl-5-Cl-naphthalene sulfonamide) (W-7) and trifluoperazine (TFP).
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Chloride; Calmodulin; Cell Membrane; Cyclic AMP; Egtazic Acid; Osteoblasts; Parathyroid Hormone; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1989 |
H1-antihistamines and calmodulin antagonists inhibit the ionophore A23187-induced eicosanoid formation by human leukocytes.
Topics: Astemizole; Benzimidazoles; Calcimycin; Calcium Channel Blockers; Eicosanoic Acids; Histamine H1 Antagonists; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Masoprocol; Piperazines; Pyrilamine; Reference Values; Sulfonamides; Trifluoperazine | 1989 |
The effect of Ca deprivation and of Ca-blocking drugs on oxytocin-induced contractions of the male mouse anococcygeus.
Topics: Animals; Calcium; Calcium Channel Blockers; Calmodulin; Egtazic Acid; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscles; Oxytocin; Sulfonamides; Trifluoperazine | 1989 |
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
Topics: Animals; Bleomycin; Calmodulin; Cell Survival; Chlorpromazine; DNA; Drug Synergism; Intercellular Signaling Peptides and Proteins; Leukemia L1210; Melitten; Mice; Peptides; Pimozide; Sulfonamides; Trifluoperazine; Wasp Venoms | 1985 |
Intracellular Ca2+ sequestration in cultured mouse fibroblasts: ATP-dependent Ca2+ uptake by saponin-permeabilized Swiss 3T3 cells.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Cell Line; Cell Membrane Permeability; Dinitrophenols; Endoplasmic Reticulum; Fibroblasts; Ionophores; Melitten; Mice; Mitochondria; Ruthenium Red; Saponins; Sulfonamides; Trifluoperazine | 1985 |
Effect of calmodulin antagonists on contraction and 45Ca movements in rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Calmodulin; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1989 |
Drug-drug interaction between cyclosporine and agents affecting calcium-dependent lymphocyte proliferation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium Channel Blockers; Cells, Cultured; Cyclosporins; Drug Interactions; Humans; Imidazoles; Isoquinolines; Lymphocyte Activation; Piperazines; Protein Kinase C; Sulfonamides; Trifluoperazine; Verapamil | 1989 |
Anti-calmodulin agents affect osmotic and angiotensin II-induced vasopressin release.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calmodulin; Culture Techniques; Hypothalamus; Imidazoles; Male; Osmolar Concentration; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1989 |
Initiation of spermiogenesis in C. elegans: a pharmacological and genetic analysis.
Topics: Animals; Caenorhabditis; Chlorpromazine; Disorders of Sex Development; Ethanolamines; Hydrogen-Ion Concentration; Male; Microscopy, Electron; Monensin; Mutation; Pronase; Sperm Motility; Spermatids; Spermatogenesis; Spermatozoa; Sulfonamides; Trifluoperazine | 1989 |
Effects of quinine and of calmodulin inhibitors on calcium-dependent potassium channels of human aorta.
Topics: Aorta; Calcium; Calmodulin; Cells, Cultured; Humans; Muscle, Smooth, Vascular; Nicardipine; Potassium Channels; Quinine; Sulfonamides; Trifluoperazine | 1989 |
Modulations by drugs of the relationship between calcium binding to troponin C and tension.
Topics: Animals; Caffeine; Calcium; Calmodulin; Chlorpromazine; In Vitro Techniques; Isometric Contraction; Melitten; Muscle Contraction; Myofibrils; Protein Binding; Quercetin; Sulfonamides; Trifluoperazine; Troponin; Troponin C | 1989 |
Calmodulin inhibitors, W-7 and TFP, block the calmodulin-independent activation of NADPH-oxidase by arachidonate in a cell-free system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calmodulin; Cell-Free System; Cytosol; Enzyme Activation; Guinea Pigs; Kinetics; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Sulfonamides; Superoxides; Trifluoperazine | 1987 |
Selective inhibitors of calmodulin-dependent phosphodiesterase and other enzymes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Cyclic Nucleotide Phosphodiesterases, Type 1; Phosphodiesterase Inhibitors; Protein Binding; Structure-Activity Relationship; Sulfonamides; Trifluoperazine; Tritium | 1988 |
Inhibition of macrophage activation by isoquinolinesulfonamides, phenothiazines, and a napthalenesulfonamide.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Fluphenazine; Guinea Pigs; Isoquinolines; Macrophage Activation; Macrophages; Male; Naphthalenes; Phenothiazines; Phosphatidylinositols; Piperazines; Protein Kinase Inhibitors; Pulmonary Alveoli; Sulfonamides; Superoxides; Trifluoperazine | 1988 |
AVP-sensitive cAMP production is dependent on calmodulin in both MTAL and MCT.
Topics: Adenylyl Cyclases; Animals; Arginine Vasopressin; Calmodulin; Colforsin; Cyclic AMP; Enzyme Activation; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Loop of Henle; Mice; Sulfonamides; Trifluoperazine | 1988 |
Mechanism of O2- (-) and H2O2-induced stimulation of sugar transport in mouse fibroblast BALB/3T3 cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Biological Transport; Calcium; Calmodulin; Catalase; Cell Line; Deoxy Sugars; Deoxyglucose; Fibroblasts; Hydrogen Peroxide; Hydrogen-Ion Concentration; Insulin; Mice; Sulfonamides; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Activation of tyrosine hydroxylase by micromolar concentrations of calcium in digitonin-permeabilized adrenal medullary cells.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Digitonin; Dose-Response Relationship, Drug; Sulfonamides; Trifluoperazine; Tyrosine 3-Monooxygenase | 1987 |
Increment of calmodulin in proportion to enhancement of non-nicotinic responses after preganglionic stimulation of the dog cardiac sympathetic ganglia.
Topics: Angiotensin II; Animals; Bethanechol; Bethanechol Compounds; Bucladesine; Calcimycin; Calmodulin; Culture Media; Cycloheximide; Dibutyryl Cyclic GMP; Dimethylphenylpiperazinium Iodide; Dogs; Electric Stimulation; Female; Ganglia, Sympathetic; Heart Conduction System; Heart Rate; Male; Nifedipine; Promethazine; Stimulation, Chemical; Sulfonamides; Trifluoperazine | 1988 |
Egg jelly triggers a calcium influx which inactivates and is inhibited by calmodulin antagonists in the sea urchin sperm.
Topics: Acrosome; Animals; Benzofurans; Calcium; Calcium Chloride; Calmodulin; Female; Fluorescent Dyes; Fura-2; Male; Membrane Potentials; Ovum; Sea Urchins; Spermatozoa; Sulfonamides; Thiobarbiturates; Trifluoperazine | 1989 |
Insulin receptor capping and its correlation with calmodulin-dependent myosin light chain kinase.
Topics: Actomyosin; Aminoquinolines; Calcium; Calmodulin; Cell Line; Cell Membrane; Concanavalin A; Cytoskeletal Proteins; Fluorometry; HLA Antigens; Humans; Immunoglobulin G; Insulin; Lectins; Lymphocytes; Microscopy, Fluorescence; Myosin-Light-Chain Kinase; Protein Kinases; Receptor, Insulin; Receptors, IgG; Receptors, Immunologic; Receptors, Mitogen; Sulfonamides; Tissue Distribution; Trifluoperazine; Wheat Germ Agglutinins | 1985 |
Subcellular action of cyclosporine: interaction between CsA and calmodulin antagonists.
Topics: Calmodulin; Cyclosporins; Drug Interactions; Humans; Imidazoles; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Sulfonamides; Trifluoperazine | 1987 |
Transforming NRK cells with avian sarcoma virus reduces the extracellular Ca2+ requirement without affecting the calcicalmodulin requirement for the G1/S transition.
Topics: Animals; Avian Sarcoma Viruses; Calcium; Calmodulin; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Culture Media; DNA Replication; Imidazoles; Interphase; Oncogene Protein pp60(v-src); Phenotype; Rats; Sulfonamides; Temperature; Trifluoperazine; Viral Proteins | 1985 |
The role of calmodulin in hormone-stimulated lipolysis.
Topics: Adipose Tissue; Animals; Calmodulin; Cyclic AMP; Enzyme Activation; Epinephrine; In Vitro Techniques; Lipolysis; Male; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1985 |
Calmodulin inhibitors decrease the CRF-and AVP-induced ACTH release in vitro: interaction of calcium-calmodulin and the cyclic AMP system.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Calcium; Calmodulin; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1985 |
Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets.
Topics: Blood Platelets; Calmodulin; Chlorpromazine; Humans; Kinetics; Perphenazine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Promazine; Sulfonamides; Tamoxifen; Trifluoperazine | 1985 |
Inhibition of the hydro-osmotic response to vasopressin and hypertonicity by phenothiazines and W7, calmodulin antagonists.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bufo marinus; Calmodulin; Cell Membrane Permeability; Chlorpromazine; Cyclic AMP; Enzyme Activation; Epithelium; Fluphenazine; Osmolar Concentration; Osmosis; Oxygen Consumption; Phenothiazines; Sulfonamides; Trifluoperazine; Urinary Bladder; Vasopressins | 1985 |
Calmodulin regulation of cellular cyclic AMP production in response to arginine vasopressin, prostaglandin E2 and forskolin in rat renal papillary collecting tubule cells in culture.
Topics: Animals; Arginine Vasopressin; Calcium; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Kidney Medulla; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sulfonamides; Trifluoperazine | 1985 |
Calmodulin-dependency of human neutrophil phosphodiesterase.
Topics: Calcium; Calmodulin; Chromatography, DEAE-Cellulose; Humans; Neutrophils; Phosphoric Diester Hydrolases; Sulfonamides; Trifluoperazine | 1986 |
Effect of trifluoperazine on rabbit cortical collecting tubular response to vasopressin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Calmodulin; Cyclic AMP; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Collecting; Osmolar Concentration; Osmosis; Rabbits; Sulfonamides; Thionucleotides; Trifluoperazine | 1986 |
Calcium, calmodulin, and cyclic adenosine monophosphate modulate prostaglandin E2 release from isolated human gastric mucosal cells.
Topics: Bucladesine; Calcimycin; Calcium; Calmodulin; Carbenoxolone; Colforsin; Cyclic AMP; Dinoprostone; Gastric Mucosa; Humans; Indomethacin; Prostaglandins E; Sulfonamides; Trifluoperazine | 1986 |
Effect of calmodulin inhibitors on thyroid hormone secretion.
Topics: Animals; Bucladesine; Calmodulin; Cyclic AMP; Male; Rats; Rats, Inbred Strains; Sulfonamides; Thyroid Gland; Thyroid Hormones; Thyroxine; Time Factors; Trifluoperazine; Triiodothyronine | 1986 |
Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin.
Topics: Animals; Bacterial Toxins; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cell Membrane Permeability; Hemolysin Proteins; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Sulfonamides; Trifluoperazine | 1987 |
Involvement of common and cell type-specific pathways in c-fos gene control: stable induction of cAMP in macrophages.
Topics: Animals; Calcium; Cell Line; Cyclic AMP; Enzyme Activation; Gene Expression Regulation; Macrophages; Mice; Phospholipids; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; RNA, Messenger; Sulfonamides; Transcription, Genetic; Trifluoperazine | 1987 |
Giardia lamblia: detection and characterization of calmodulin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acids; Animals; Brain Chemistry; Calmodulin; Cattle; Enzyme Activation; Fluphenazine; Giardia; Molecular Weight; Myocardium; Sulfonamides; Trifluoperazine | 1987 |
Identification of calmodulin activity in purified retroviruses.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calmodulin; Leukemia Virus, Feline; Radioimmunoassay; Sulfonamides; Trifluoperazine | 1986 |
Comparison of the roles of calmodulin and protein kinase C in activation of the human neutrophil respiratory burst.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calmodulin; Humans; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Piperazines; Protein Kinase C; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
The roles of Ca2+ and adenosine 3',5'-monophosphate in the regulation of progesterone production by human placental tissue.
Topics: Calcimycin; Calcium; Calmodulin; Cyclic AMP; Female; Humans; Isoproterenol; Placenta; Pregnancy; Progesterone; Propranolol; Sulfonamides; Terbutaline; Trifluoperazine | 1987 |
Calmodulin antagonists suppress cholesterol synthesis by inhibiting sterol delta 24 reductase.
Topics: Calmodulin; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cholesterol; Fibroblasts; Humans; Kinetics; Liver Neoplasms; Oxidoreductases; Skin; Sulfonamides; Trifluoperazine | 1987 |
Effects of calmodulin antagonists on hormone release and cyclic AMP levels in GH3 pituitary cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Division; Cell Line; Chlorpromazine; Cyclic AMP; Growth Hormone; Pituitary Neoplasms; Prolactin; Rats; Sulfonamides; Trifluoperazine | 1987 |
The inhibitory effects of calmodulin antagonists on TSH-stimulated thyroid hormone release by mouse thyroid lobes.
Topics: Animals; Bucladesine; Calmodulin; Cyclic AMP; Lactates; Male; Mice; Prenylamine; Sulfonamides; Thyroid Gland; Thyrotropin; Thyroxine; Trifluoperazine | 1987 |
Identification of calmodulin-like activity in term human amnion: effect of calmodulin inhibitors on prostaglandin biosynthesis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amnion; Calcimycin; Calcium; Calmodulin; Cytosol; Dinoprostone; Female; Humans; Imidazoles; Microsomes; Pregnancy; Prostaglandins E; Sulfonamides; Trifluoperazine | 1987 |
Both protein kinase C and calcium mediate activation of the Na+/H+ antiporter in Chinese hamster embryo fibroblasts.
Topics: Animals; Calcimycin; Calcium; Carrier Proteins; Cell Line; Cricetinae; Embryo, Mammalian; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Hydrogen-Ion Concentration; Protein Kinase C; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1987 |
Inhibition of secretion of rat calcitonin by calmodulin inhibitors.
Topics: Animals; Calcitonin; Calcium; Calmodulin; Chlorpromazine; Haloperidol; In Vitro Techniques; Male; Parathyroid Glands; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sulfonamides; Thyroid Gland; Trifluoperazine | 1986 |
Stimulatory effect of calmodulin antagonists on phospholipid base-exchange reactions in rabbit platelet membranes.
Topics: Animals; Binding, Competitive; Blood Platelets; Calcium; Calmodulin; Cell Membrane; Chlorpromazine; Choline; Ethanolamines; Phospholipids; Rabbits; Serine; Sulfonamides; Trifluoperazine | 1986 |
Synergistic effect of retinoic acid and calcium ionophore A23187 on differentiation, c-myc expression, and membrane tyrosine kinase activity in human promyelocytic leukemia cell line HL-60.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calmodulin; Cell Differentiation; Cell Line; Cell Membrane; Drug Synergism; Gene Expression Regulation; Hematopoiesis; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogenes; RNA, Messenger; Sulfonamides; Tretinoin; Trifluoperazine | 1987 |
Antagonism of calmodulin-stimulated adenylate cyclase by trifluoperazine, calmidazolium and W-7 in rat cerebellar membranes.
Topics: Adenylyl Cyclases; Animals; Calmodulin; Cerebellum; Chlorpromazine; Dose-Response Relationship, Drug; Egtazic Acid; Imidazoles; Membranes; Rats; Sulfonamides; Trifluoperazine | 1987 |
Calmodulin antagonist effects on GnRH and secretogogue-induced release of bovine LH.
Topics: Animals; Calcimycin; Calmodulin; Cattle; Dinoprostone; Female; Gonadotropin-Releasing Hormone; Imidazoles; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Prostaglandins E; Sulfonamides; Trifluoperazine | 1988 |
Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists.
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calmodulin; Chlorpromazine; Chromatography, High Pressure Liquid; Cytochalasin B; Linoleic Acid; Linoleic Acids; Macrophage Activation; Macrophages; Oleic Acid; Oleic Acids; Opsonin Proteins; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Pulmonary Alveoli; Quinacrine; Rabbits; Sulfonamides; Trifluoperazine; Zymosan | 1988 |
Phase-shifts of the Bulla ocular circadian pacemaker in the presence of calmodulin antagonists.
Topics: Animals; Calmodulin; Circadian Rhythm; Imidazoles; Mollusca; Sulfonamides; Trifluoperazine | 1988 |
External ATP-induced passive permeability change and cell lysis of cultured transformed cells: action in serum-containing growth media.
Topics: Adenosine Triphosphate; Animals; Blood; Calcium; Calmodulin; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Culture Media; Magnesium; Melanoma; Mice; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1988 |
[Effect of calmodulin inhibitor on proliferation and doxorubicin-sensitivity in cultured cancer cells].
Topics: Calmodulin; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stimulation, Chemical; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured | 1988 |
Calmodulin antagonists inhibit the phagocytic activity of cultured Kupffer cells.
Topics: Actins; Animals; Calmodulin; Cells, Cultured; Chlorpromazine; Female; Kupffer Cells; Microspheres; Phagocytosis; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1988 |
Calmodulin antagonists increase the amount of mRNA for the low-density-lipoprotein receptor in skin fibroblasts.
Topics: Actins; Calmodulin; Cells, Cultured; Electrophoresis, Agar Gel; Fibroblasts; Humans; Nucleic Acid Hybridization; Receptors, LDL; RNA, Messenger; Skin; Sulfonamides; Trifluoperazine | 1988 |
A possible role for calmodulin in Ca2+-induced swelling of mitochondria.
Topics: Animals; Calcium; Calmodulin; In Vitro Techniques; Light; Mitochondria, Liver; Mitochondrial Swelling; Rats; Rats, Inbred Strains; Scattering, Radiation; Sulfonamides; Trifluoperazine | 1987 |
Does calmodulin participate as an intermediate in the process of glycogenolysis in rat submandibular gland?
Topics: Animals; Calmodulin; Chlorpromazine; Glycogen; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Submandibular Gland; Sulfonamides; Trifluoperazine | 1987 |
Effects of phenothiazines and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide on rat colonic absorption of cefmetazole.
Topics: Animals; Biological Availability; Calmodulin; Cefmetazole; Cephamycins; Chromatography, High Pressure Liquid; Colon; Intestinal Absorption; Male; Perphenazine; Phenothiazines; Promethazine; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1986 |
Comparative antiarrhythmic and electrophysiological effects of drugs known to inhibit calmodulin (TFP, W7 and bepridil).
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bepridil; Calmodulin; Coronary Vessels; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Ligation; Male; Phentolamine; Phenylephrine; Pyrrolidines; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1986 |
Calmodulin antagonists inhibit latch bridges in detergent skinned swine carotid media.
Topics: Adenosine Triphosphate; Animals; Calcium; Calmodulin; Carotid Arteries; Cytidine Triphosphate; Detergents; Imidazoles; In Vitro Techniques; Magnesium; Muscle Contraction; Myosins; Osmolar Concentration; Phosphorylation; Sulfonamides; Swine; Trifluoperazine | 1987 |
Effects of calcium-antagonists and calmodulin inhibitors on DNA synthesis in cultured rat vascular smooth muscle cells.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diltiazem; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Nicardipine; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Verapamil | 1987 |
Possible role of calcium in parathyroid hormone action on phosphate transport in rabbit renal proximal tubules.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Kidney Tubules, Proximal; Microvilli; Parathyroid Hormone; Phosphates; Rabbits; Sulfonamides; Trifluoperazine | 1986 |
Characteristics of calmodulin binding to purified human lymphocyte plasma membranes.
Topics: Calcium; Calmodulin; Cell Fractionation; Cell Membrane; Cell-Free System; Chlorpromazine; Cytoplasm; Humans; Kinetics; Lymphocytes; Membrane Proteins; Molecular Weight; Protein Binding; Sulfonamides; Trifluoperazine | 1987 |
Effects of calmodulin antagonists on secretion of bile and bile acid.
Topics: Animals; Bile; Bile Acids and Salts; Calmodulin; Chlorpromazine; In Vitro Techniques; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1987 |
[Changes of erythrocyte deformability induced by calcium accumulation and calmodulin inhibitors].
Topics: Calcium; Calmodulin; Cytoskeletal Proteins; Energy Metabolism; Erythrocyte Deformability; Erythrocytes; Humans; Ions; Potassium; Sodium; Sulfonamides; Trifluoperazine | 1987 |
Calmodulin inhibitors protect against cadmium-induced testicular damage in mice.
Topics: Animals; Cadmium; Cadmium Chloride; Calmodulin; Chlorpromazine; Edema; Endothelium, Vascular; Hemorrhage; Male; Mice; Organ Size; Sulfonamides; Testicular Diseases; Testis; Trifluoperazine | 1987 |
Stimulation by trifluoperazine of p-aminohippurate accumulation in rat kidney cortical slices.
Topics: Adenosine Triphosphate; Aminohippuric Acids; Animals; Chlorpromazine; Dibucaine; Hemolysis; In Vitro Techniques; Kidney Cortex; Male; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1987 |
Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cell Survival; Cells, Cultured; Hypoxia; Isomerism; Nephrons; Nifedipine; Rabbits; Sulfonamides; Time Factors; Trifluoperazine; Verapamil | 1986 |
H-NMR studies of calmodulin: the effect of W-7 (N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide) and Ca2+ on conformational changes of calmodulin.
Topics: Calcium; Calmodulin; Magnetic Resonance Spectroscopy; Protein Conformation; Sulfonamides; Trifluoperazine | 1986 |
Does the binding of cyclosporine to calmodulin result in immunosuppression?
Topics: Animals; Calmodulin; Cyclosporine; Cyclosporins; Immune Tolerance; Lymphocyte Activation; Mice; Muscle Contraction; Muscle, Smooth; Stereoisomerism; Sulfonamides; Trifluoperazine | 1986 |
Identification of calmodulin in new-born rat calvaria.
Topics: Animals; Animals, Newborn; Autoradiography; Calmodulin; Chromatography, DEAE-Cellulose; Electrophoresis, Polyacrylamide Gel; Proteins; Rats; Skull; Sulfonamides; Trifluoperazine | 1986 |
A role for calmodulin in renal production of 1,25-dihydroxyvitamin D3.
Topics: Animals; Calcifediol; Calcitriol; Calcium; Calmodulin; Chickens; Imidazoles; Kidney Tubules; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Sulfonamides; Trifluoperazine; Vitamin D Deficiency | 1986 |
Endogenous dopamine release from tuberoinfundibular neurons: does calmodulin play any role?
Topics: Animals; Arcuate Nucleus of Hypothalamus; Calmodulin; Dopamine; Female; In Vitro Techniques; Median Eminence; Pimozide; Potassium; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1986 |
Enhancement of spontaneous acetylcholine release from motor nerve terminal by calmodulin inhibitors.
Topics: Acetylcholine; Animals; Calmodulin; In Vitro Techniques; Male; Membrane Potentials; Motor Endplate; Motor Neurons; Nerve Endings; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine | 1986 |
Mechanism of action of angiotensin II and bradykinin on prostaglandin synthesis and vascular tone in the isolated rat kidney. Effect of Ca++ antagonists and calmodulin inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Bradykinin; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Dantrolene; Diltiazem; Dinoprostone; Gallic Acid; Imidazoles; Indomethacin; Kidney; Male; Nicotinic Acids; Nimodipine; Prostaglandins E; Quinacrine; Rats; Rats, Inbred Strains; Ryanodine; Stimulation, Chemical; Sulfonamides; Trifluoperazine; Vasoconstriction | 1985 |
Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: membrane attack and calcium influx.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Calmodulin; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Cytotoxins; Endothelium; Epoprostenol; Models, Biological; Pseudomonas aeruginosa; Pulmonary Artery; Sulfonamides; Swine; Trifluoperazine | 1985 |
Effects of protease inhibitors and calmodulin inhibitors on Ca2+ influx and catecholamine secretion in isolated bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Calcium; Calmodulin; Catecholamines; Cattle; Chlorpromazine; Gabexate; Guanidines; In Vitro Techniques; Promethazine; Protease Inhibitors; Sulfonamides; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Trifluoperazine | 1985 |
Effect of intracellular free Ca2+ on leucine transport in Chang liver cells.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport, Active; Body Fluids; Calcimycin; Calcium; Cells, Cultured; Chlorpromazine; Demecolcine; Drug Interactions; Humans; Intracellular Fluid; Kinetics; Leucine; Liver; Microtubules; Sulfonamides; Trifluoperazine | 1985 |
The effects of anticalmodulin drugs on the ultrastructure of boar spermatozoa.
Topics: Acrosome; Animals; Calmodulin; Fluorescein-5-isothiocyanate; Fluoresceins; Imidazoles; Lectins; Male; Microscopy, Electron; Microscopy, Fluorescence; Plant Lectins; Spermatozoa; Sulfonamides; Swine; Thiocyanates; Trifluoperazine | 1985 |
Trifluoperazine and W-7 inhibit mating in Chlamydomonas at an early stage of gametic interaction.
Topics: Calmodulin; Cell Movement; Chlamydomonas; Crosses, Genetic; Flagella; Kinetics; Sulfonamides; Trifluoperazine | 1986 |
Micromolar concentrations of free calcium provoke secretion of lysozyme from human neutrophils permeabilized with saponin.
Topics: Adult; Buffers; Calcium; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Muramidase; Neutrophils; Saponins; Sulfonamides; Trifluoperazine | 1985 |
The response of non-pregnant rat myometrium to oxytocin in Ca-free solution.
Topics: Animals; Caffeine; Calcium; Chlorpromazine; Female; Fluphenazine; In Vitro Techniques; Myometrium; Oxytocin; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Uterine Contraction | 1985 |
Disparate effects of calmodulin inhibitors on corneal epithelial migration in rabbit and rat.
Topics: Animals; Calmodulin; Cornea; Corneal Injuries; Culture Techniques; Epithelium; Male; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Sulfonamides; Trifluoperazine; Wound Healing | 1985 |
Possible role of calcium mediators in parathyroid hormone action on phosphate transport in rabbit renal brush border membrane.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basement Membrane; Biological Transport, Active; Calcium; Kidney Cortex; Male; Microvilli; Parathyroid Hormone; Phosphates; Rabbits; Sulfonamides; Time Factors; Trifluoperazine | 1985 |
Reciprocal effects of phenothiazines and naphthalene sulfonamides on the external ATP-dependent permeability change in Chinese hamster ovary cells.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Cell Line; Cell Membrane Permeability; Chlorpromazine; Cricetinae; Cricetulus; Female; Ovary; Phenothiazines; Potassium Cyanide; Rotenone; Sulfonamides; Trifluoperazine | 1985 |
Different corneal epithelial healing mechanisms in rat and rabbit: role of actin and calmodulin.
Topics: Actins; Animals; Calmodulin; Cell Movement; Cornea; Cytochalasin B; Epithelium; Male; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Sulfonamides; Trifluoperazine; Wound Healing | 1985 |
Pharmacological properties of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), a calmodulin antagonist in arterial strips from rats and rabbits.
Topics: Animals; Aorta; Calcium; Calmodulin; Female; Gallopamil; In Vitro Techniques; Muscle, Smooth, Vascular; Potassium; Rabbits; Rats; Rats, Inbred WKY; Sulfonamides; Trifluoperazine; Vasoconstriction | 1985 |
Inhibitors of calcium-dependent enzymes prevent the onset of afterdischarge in the peptidergic bag cell neurons of Aplysia.
Topics: Animals; Aplysia; Evoked Potentials; Imidazoles; Neurons; Protein Kinase Inhibitors; Reaction Time; Sulfonamides; Trifluoperazine | 1985 |
Effect of calmodulin antagonists on calcium and ethanol-induced sleeping time in mice.
Topics: Animals; Biogenic Amines; Calcium; Calcium Chloride; Calmodulin; Ethanol; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Sleep; Sulfonamides; Time Factors; Trifluoperazine | 1985 |
Effects of Ca2+ and calmodulin antagonists on the oxygen uptake induced by acetylcholine or substance P in rat submandibular gland slices.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calmodulin; Chlorpromazine; Diltiazem; In Vitro Techniques; Lanthanum; Male; Oxygen Consumption; Rats; Rats, Inbred Strains; Submandibular Gland; Substance P; Sulfonamides; Trifluoperazine; Vasodilator Agents; Verapamil | 1984 |
Two types of calmodulin antagonists: a structurally related interaction.
Topics: Animals; Calmodulin; Cattle; Enzyme Activation; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Prenylamine; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfonamides; Trifluoperazine | 1984 |
Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Neutrophils; Protease Inhibitors; Sulfonamides; Superoxides; Trifluoperazine; Tyrosine | 1984 |
Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calmodulin; Cattle; Chromatography, Affinity; Cyanogen Bromide; Enzyme Activation; Nerve Tissue Proteins; Sulfonamides; Trifluoperazine | 1984 |
Trifluoperazine inhibits phagocytosis in a macrophagelike cultured cell line.
Topics: Alkaloids; Animals; Calcium-Binding Proteins; Calmodulin; Cell Division; Cell Line; Cell Survival; Macrophages; Mice; Muramidase; Paclitaxel; Phagocytosis; Sulfonamides; Trifluoperazine | 1981 |
Inhibitory effects of calmodulin antagonists on plasma membrane cyclases in Tetrahymena: calmodulin-dependent guanylate cyclase and calmodulin-independent adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Calcium; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Egtazic Acid; Guanylate Cyclase; Kinetics; Sulfonamides; Tetrahymena pyriformis; Trifluoperazine; Vasodilator Agents | 1983 |
Ca2+-stimulated, Mg2+-dependent ATPase activity in neutrophil plasma membrane vesicles. Coupling to Ca2+ transport.
Topics: Animals; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Cell Membrane; Guinea Pigs; Hydrogen-Ion Concentration; Neutrophils; Nucleotides; Sulfonamides; Trifluoperazine | 1984 |
Calmodulin antagonists stimulate renin release from isolated rat glomeruli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Isoproterenol; Kidney Glomerulus; Kinetics; Male; Rats; Rats, Inbred Strains; Renin; Sulfonamides; Trifluoperazine; Triflupromazine | 1983 |
Inhibition of histamine release from human basophils in vitro by calmodulin antagonists.
Topics: Adult; Basophils; Binding Sites; Calcium-Binding Proteins; Calmodulin; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunosuppressive Agents; Sulfonamides; Trifluoperazine | 1983 |
The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils.
Topics: Adult; Calcium; Cytochalasin B; Diamines; Egtazic Acid; Gallic Acid; Glucuronidase; Humans; Lysosomes; Neutrophils; Oxygen; Sulfonamides; Superoxides; Trifluoperazine | 1981 |
The effect of various stimuli and calcium antagonists on the fluorescence response of chlorotetracycline-loaded human neutrophils.
Topics: Calcium; Chlortetracycline; Concanavalin A; Egtazic Acid; Gallic Acid; Glucuronidase; Humans; Lysosomes; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phorbols; Spectrometry, Fluorescence; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine; Vasodilator Agents | 1982 |
Calmodulin antagonists' binding sites on calmodulin.
Topics: Animals; Binding Sites; Calcium-Binding Proteins; Calmodulin; Cattle; Chemical Phenomena; Chemistry; Oxidation-Reduction; Phosphoric Diester Hydrolases; Protein Binding; Sulfonamides; Trifluoperazine; Troponin; Troponin I | 1983 |
Role of calcium and calmodulin in activation of the oxyntic cell by histamine and carbamylcholine in the guinea pig.
Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Carbachol; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Ion Channels; Pimozide; Sulfonamides; Trifluoperazine | 1983 |
A possible role for calmodulin in human thyroid cell metabolism.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Calmodulin; Cells, Cultured; Cyclic AMP; Humans; Prochlorperazine; Sulfonamides; Thyroid Gland; Thyrotropin; Trifluoperazine | 1983 |
Calmodulin antagonists inhibit secretion in Paramecium.
Topics: Animals; Calcimycin; Calcium-Binding Proteins; Calmodulin; Cytoplasmic Granules; Exocytosis; Paramecium; Picrates; Sulfonamides; Trifluoperazine | 1983 |
Potent antitumor promoting activity of N-6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, in mouse skin tumor formation induced by 7,12-dimethylbenz[a]anthracene plus teleocidin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benz(a)Anthracenes; Carcinogens; Drug Antagonism; Female; Fibroblasts; Lyngbya Toxins; Mice; Mice, Inbred ICR; Phospholipids; Skin Neoplasms; Sulfonamides; Trifluoperazine | 1984 |
Calmodulin antagonists inhibit formation of platelet-activating factor in stimulated human neutrophils.
Topics: Calcimycin; Calcium; Calmodulin; Humans; Kinetics; Neutrophils; Platelet Activating Factor; Sulfonamides; Trifluoperazine | 1984 |
Staphylococcal alpha-toxin elicits hypertension in isolated rabbit lungs. Evidence for thromboxane formation and the role of extracellular calcium.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Blood Pressure; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Gallic Acid; Hemolysin Proteins; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Lung; Prostaglandins; Pulmonary Artery; Rabbits; Sulfonamides; Thromboxanes; Trifluoperazine | 1984 |
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin.
Topics: ADP Ribose Transferases; Animals; Bacterial Toxins; Calmodulin; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Exotoxins; Kidney; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Protein Biosynthesis; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Rats; Sulfonamides; Tretinoin; Trifluoperazine; Virulence Factors | 1984 |
Possible role of calmodulin in the control of lysosomal enzyme release from human polymorphonuclear leukocytes.
Topics: Calcium; Calmodulin; Humans; In Vitro Techniques; Lysosomes; Muramidase; Neutrophils; Phenothiazines; Phospholipases A; Sulfonamides; Trifluoperazine; Ultraviolet Rays | 1984 |
Calmodulin antagonists inhibit activity of myosin light-chain kinase independent of calmodulin.
Topics: Animals; Calmodulin; Cattle; Imidazoles; Myosin-Light-Chain Kinase; Myosins; Protein Binding; Protein Kinase Inhibitors; Spectrometry, Fluorescence; Sulfonamides; Trifluoperazine | 1984 |
Characterization of the activity of growth factor from AH-130 tumor cells.
Topics: Animals; Cadaverine; DNA Replication; Epidermal Growth Factor; Ethylamines; Fibroblasts; Growth Substances; Liver; Membrane Proteins; Methylamines; Mice; Neoplasms, Experimental; Phosphorylation; Rats; Sulfonamides; Trifluoperazine | 1984 |
Inhibition of glia maturation factor-induced mitogenesis in glioblasts by calmodulin antagonists.
Topics: Animals; Calcium; Calmodulin; Cell Division; Cells, Cultured; DNA; Glia Maturation Factor; Nerve Tissue Proteins; Neuroglia; Rats; Sulfonamides; Thymidine; Trifluoperazine | 1983 |
Calmodulin antagonists enhance calcium binding to calmodulin.
Topics: Animals; Binding Sites; Calcium; Calmodulin; Cattle; In Vitro Techniques; Protein Conformation; Structure-Activity Relationship; Sulfonamides; Trifluoperazine | 1983 |
Inhibition of human breast cancer colony formation by anticalmodulin agents: trifluoperazine, W-7, and W-13.
Topics: Breast Neoplasms; Calmodulin; Cell Division; Cell Line; Female; Humans; Sulfonamides; Trifluoperazine | 1983 |
Calmodulin antagonists inhibit aggregation of human, guniea pig and rabbit platelets induced with platelet activating factor.
Topics: Animals; Calcium-Binding Proteins; Calmodulin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sulfonamides; Trifluoperazine | 1983 |
Calcium and calmodulin antagonists binding to calmodulin and relaxation of coronary segments.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Coronary Vessels; Felodipine; Myocardial Contraction; Nifedipine; Sulfonamides; Swine; Trifluoperazine; Vasodilator Agents | 1983 |
Effect of calcium-antagonist and calmodulin-antagonist drugs on calmodulin-dependent contractions of chemically skinned vascular smooth muscle from rabbit renal arteries.
Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Renal Artery; Sulfonamides; Trifluoperazine | 1983 |
Effects of calmodulin-binding drugs on the guinea pig spermatozoon acrosome reaction and the use of these drugs as vaginal contraceptive agents in rabbits.
Topics: Acrosome; Anilino Naphthalenesulfonates; Animals; Calcium; Calmodulin; Cations, Divalent; Chlorpromazine; Contraceptive Agents; Female; Fluphenazine; Male; Phenothiazines; Rabbits; Spermatozoa; Sulfonamides; Trifluoperazine; Vaginal Creams, Foams, and Jellies | 1982 |
Inhibition by calmodulin antagonists of glioblast DNA synthesis and morphological changes induced by glia maturation factor.
Topics: Animals; Brain; Calcium-Binding Proteins; Calmodulin; Cattle; Cells, Cultured; DNA Replication; Female; Fetus; Glia Maturation Factor; Kinetics; Nerve Tissue Proteins; Neuroglia; Pregnancy; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1982 |
Involvement of calmodulin in granulocyte chemotaxis: the effect of calmodulin inhibitors.
Topics: Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cell Movement; Chemotaxis, Leukocyte; Granulocytes; In Vitro Techniques; Magnesium; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Rabbits; Sulfonamides; Trifluoperazine | 1982 |
Evidence that calmodulin may be involved in phytohaemagglutinin-stimulated lymphocyte division.
Topics: Calcium-Binding Proteins; Calmodulin; DNA Replication; Humans; Lymphocyte Activation; Lymphocytes; Nifedipine; Phytohemagglutinins; Pyridines; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1982 |
Calmodulin antagonists modulate rabbit neutrophil degranulation, aggregation and stimulated oxygen consumption.
Topics: Animals; Ascitic Fluid; Calcium-Binding Proteins; Calmodulin; Cell Aggregation; Chemotactic Factors; Cytoplasmic Granules; Diamines; Dose-Response Relationship, Drug; Lysosomes; Neutrophils; Oxygen Consumption; Rabbits; Sulfonamides; Trifluoperazine | 1981 |
Calmodulin inhibitors block neutrophil degranulation at a step distal from the mobilization of calcium.
Topics: Animals; Biological Transport, Active; Calcium; Calmodulin; Cytochalasin B; Diamines; Glucuronidase; Kinetics; Lysosomes; Neutrophils; Rabbits; Sulfonamides; Trifluoperazine | 1980 |
Effects of various calmodulin antagonists on Na/Ca exchange current of single ventricular cells of guinea-pig.
Topics: Animals; Benzimidazoles; Calcium; Calmodulin; Carrier Proteins; Guinea Pigs; Heart Ventricles; Imidazoles; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Melitten; Myocardium; Peptides; Ruthenium Red; Sodium; Sodium-Calcium Exchanger; Sulfonamides; Trifluoperazine; Wasp Venoms | 1993 |
Inhibition of olfactory cyclic nucleotide-activated current by calmodulin antagonists.
Topics: Animals; Calmodulin; Chloride Channels; Cilia; Cyclic AMP; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Neurons, Afferent; Olfactory Mucosa; Olfactory Pathways; Rana pipiens; Receptors, Odorant; Sulfonamides; Trifluoperazine | 1994 |
The effect of caffeine on prostaglandin output from the guinea-pig uterus.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calmodulin; Female; Gallic Acid; Guinea Pigs; Prostaglandins; Ruthenium Red; Ryanodine; Stimulation, Chemical; Sulfonamides; Theophylline; Trifluoperazine; Uterus; Vasodilator Agents | 1994 |
Occurrence of novel types of nitric oxide synthase in the silkworm, Bombyx mori.
Topics: Amino Acid Oxidoreductases; Animals; Bombyx; Calmodulin; Dose-Response Relationship, Drug; Enzyme Induction; Fat Body; Isoenzymes; Kinetics; Lipopolysaccharides; Malpighian Tubules; Nitric Oxide Synthase; Sulfonamides; Trifluoperazine | 1995 |
Dual regulation of cGMP formation by calcium in pancreatic acinar cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Oxidoreductases; Animals; Calcium; Calcium-Binding Proteins; Calmodulin; Cyclic GMP; Cytosol; Guanylate Cyclase; Guinea Pigs; Homeostasis; Imidazoles; In Vitro Techniques; Isoquinolines; Kinetics; Nitric Oxide Synthase; Pancreas; Piperazines; Protein Kinase C; Staurosporine; Sulfonamides; Trifluoperazine | 1995 |
Regulation of immune complexes binding of macrophages by pectic polysaccharide from Bupleurum falcatum L.: pharmacological evidence for the requirement of intracellular calcium/calmodulin on Fc receptor up-regulation by bupleuran 2IIb.
Topics: Animals; Anti-Ulcer Agents; Antigen-Antibody Complex; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Gallic Acid; Gene Expression Regulation; Isoquinolines; Macrophages, Peritoneal; Male; Mice; Pectins; Protein Kinase C; Receptors, Fc; Signal Transduction; Sulfonamides; Transcription, Genetic; Trifluoperazine; Up-Regulation | 1995 |
A rice membrane calcium-dependent protein kinase is induced by gibberellin.
Topics: Animals; Antibodies; Calmodulin; Cell Membrane; Chromatography, Affinity; Chromatography, Ion Exchange; Enzyme Induction; Gibberellins; Kinetics; Mammals; Molecular Weight; Oryza; Phosphorylation; Protein Kinase C; Protein Kinases; Seeds; Sulfonamides; Trifluoperazine | 1995 |
Cytosolic Ca2+ dynamics in hamster ascending thin limb of Henle's loop.
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Cricetinae; Cytosol; In Vitro Techniques; Kidney Tubules; Kinetics; Loop of Henle; Male; Mesocricetus; Nicardipine; Perfusion; Potassium; Sodium Cyanide; Sulfonamides; Time Factors; Trifluoperazine | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, reverses the inhibitory effect of insulin on lipolysis due to dibutyryl cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Bucladesine; Calmodulin; Cells, Cultured; Dose-Response Relationship, Drug; Epididymis; Epinephrine; Imidazoles; Insulin; Insulin Antagonists; Kinetics; Lipolysis; Male; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Sulfonamides; Trifluoperazine | 1993 |
Sodium fluoride stimulates exocytosis at a late site of calcium interaction in stimulus-secretion coupling: studies with the RINm5F beta cell line.
Topics: Aluminum; Animals; Arachidonic Acid; Calcium; Calcium-Binding Proteins; Cell Line; Colforsin; Cyclic AMP; Deferoxamine; Exocytosis; Extracellular Space; Insulin; Insulin Secretion; Ionomycin; Islets of Langerhans; Kinetics; Melitten; Nitrendipine; Potassium Chloride; Protein Kinase C; Secretory Rate; Sodium Fluoride; Stimulation, Chemical; Sulfonamides; Temperature; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1995 |
Attenuation of ultraviolet radiation-induced edema and erythema with topical calmodulin and protein kinase C inhibitors.
Topics: Absorption; Administration, Cutaneous; Animals; Calmodulin; Dose-Response Relationship, Drug; Edema; Erythema; Female; Guinea Pigs; Mice; Mice, Hairless; Mice, Inbred Strains; Protein Kinase C; Skin; Skin Diseases; Skinfold Thickness; Sulfonamides; Sunscreening Agents; Trifluoperazine; Ultraviolet Rays | 1994 |
Role of calcium in the regulation of ornithine decarboxylase enzyme activity in mouse colon cancer cells.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Colonic Neoplasms; Ion Transport; Mice; Nifedipine; Ornithine Decarboxylase; Potassium Chloride; Sulfonamides; Trifluoperazine; Tumor Cells, Cultured; Verapamil | 1995 |
Evidence for a functional interaction between calmodulin and the glucocorticoid receptor.
Topics: Animals; Blotting, Western; Calmodulin; Chloramphenicol O-Acetyltransferase; Chromatography, Affinity; Cytosol; Dexamethasone; Gene Expression; HSP90 Heat-Shock Proteins; Kinetics; L Cells; Mice; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Receptors, Glucocorticoid; Signal Transduction; Sulfonamides; Transfection; Trifluoperazine | 1995 |
Calmodulin antagonists inhibit human immunodeficiency virus-induced cell fusion but not virus replication.
Topics: Calmodulin; Cell Division; Cell Fusion; Cell Line; Cytopathogenic Effect, Viral; Gene Products, env; HeLa Cells; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Protein Processing, Post-Translational; Sulfonamides; T-Lymphocytes; Trifluoperazine; Virus Replication | 1994 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Regulation of flagellar motility of fowl spermatozoa: evidence for the involvement of intracellular free Ca2+ and calmodulin.
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Cells, Cultured; Chickens; Egtazic Acid; Intracellular Fluid; Male; Sperm Motility; Spermatozoa; Sulfonamides; Trifluoperazine | 1994 |
Synergy between phorbol esters and retinoic acid in inducing protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Chlorpromazine; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Isoquinolines; Kinetics; Phosphorylation; Piperazines; Protein Binding; Protein Kinase C; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Tretinoin; Trifluoperazine; Tritium | 1994 |
Overexpression of the myristoylated alanine-rich C-kinase substrate in Rat1 cells increases sensitivity to calmodulin antagonists.
Topics: Animals; Biological Transport; Calmodulin; Cell Cycle; Cell Membrane; Cells, Cultured; Cytoplasm; DNA; DNA Replication; Fibroblasts; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Sulfonamides; Transfection; Trifluoperazine | 1994 |
Autoradiographic distribution and characteristics of high- and low-affinity polyamine-sensitive [3H]ifenprodil sites in the rat brain: possible relationship to NMDAR2B receptors and calmodulin.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Calmodulin; Hippocampus; Imidazoles; Male; Piperidines; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sepharose; Spermidine; Spermine; Sulfonamides; Tissue Distribution; Trifluoperazine; Tritium | 1994 |
Enhancement of metallothionein gene expression in male Wistar (WF/NCr) rats by treatment with calmodulin inhibitors: potential role of calcium regulatory pathways in metallothionein induction.
Topics: Animals; Base Sequence; Cadmium; Cadmium Chloride; Calcimycin; Calmodulin; Chlorides; Chlorpromazine; Gene Expression Regulation; Imidazoles; Kidney; Liver; Male; Metallothionein; Molecular Sequence Data; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Testis; Trifluoperazine | 1994 |
Involvement of plasma membrane-located calmodulin in the response decay of cyclic nucleotide-gated cation channel of cultured carrot cells.
Topics: Biological Transport; Calcium Channels; Calmodulin; Cell Membrane; Cells, Cultured; Cyclic AMP; Ion Channel Gating; Sulfonamides; Trifluoperazine; Vegetables | 1994 |
The effect of 3 calmodulin antagonists on K(+)-stimulated neurotransmitter release from rat cortical slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calmodulin; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Kinetics; Piperazines; Potassium; Rats; Serotonin; Sulfonamides; Trifluoperazine | 1993 |
Calmodulin antagonists induce changes in lens permeability and transparency.
Topics: Animals; Calcium; Calmodulin; Cataract; Cell Membrane Permeability; Imidazoles; Lens, Crystalline; Membrane Potentials; Rats; Rats, Wistar; Sodium; Sulfonamides; Trifluoperazine | 1994 |
Polyamine transport regulation by calcium and calmodulin: role of Ca(2+)-ATPase.
Topics: Biological Transport; Calcium; Calcium-Transporting ATPases; Calmodulin; Egtazic Acid; Humans; Lanthanum; Melitten; Spermidine; Sulfonamides; Terpenes; Thapsigargin; Trifluoperazine; Tumor Cells, Cultured | 1993 |
Involvement of Ca(2+)-calmodulin in platelet-derived growth factor-, fibroblast growth factor-, and insulin-induced ornithine decarboxylase in NIH-3T3 cells.
Topics: 3T3 Cells; Animals; Calcium; Calmodulin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Fibroblast Growth Factor 2; Insulin; Mice; Ornithine Decarboxylase; Platelet-Derived Growth Factor; Sulfonamides; Time Factors; Trifluoperazine | 1994 |
Second messenger regulation of occlusion of the spinal neurocoel in the chick embryo.
Topics: Animals; Bucladesine; Calcimycin; Calmodulin; Cell Differentiation; Chick Embryo; Chlorpromazine; Colforsin; Cyclic AMP; Second Messenger Systems; Spinal Cord; Sulfonamides; Trifluoperazine | 1993 |
Sphingosine, W-7, and trifluoperazine inhibit the elevation in cytosolic calcium induced by high K+ depolarization in synaptosomes.
Topics: Animals; Brain; Calcium; Cytosol; Electrophysiology; Potassium; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sphingosine; Sulfonamides; Synaptosomes; Trifluoperazine | 1993 |
Influence of calmodulin antagonists and calcium channel blockers on triiodothyronine uptake by rat hepatoma and myoblast cell lines.
Topics: Analysis of Variance; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calmodulin; Cell Line; Diltiazem; Imidazoles; Iodine Radioisotopes; Liver Neoplasms, Experimental; Magnesium; Muscles; Nifedipine; Protein Kinase C; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Triiodothyronine; Tumor Cells, Cultured; Verapamil | 1993 |
Blockade by calmodulin inhibitors of Ca2+ channels in smooth muscle from rat vas deferens.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calmodulin; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nimodipine; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Sulfonamides; Trifluoperazine; Vas Deferens | 1993 |
The influence of thapsigargin on Na,K-ATPase activity in cultured nonpigmented ciliary epithelial cells.
Topics: Adenosine Triphosphate; Calcium; Calmodulin; Cell Line, Transformed; Cell Membrane Permeability; Ciliary Body; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Hydrolysis; L-Lactate Dehydrogenase; Ouabain; Pigment Epithelium of Eye; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Terpenes; Thapsigargin; Trifluoperazine | 1995 |
Divalent cation channels activated by phenothiazines in membrane of rat ventricular myocytes.
Topics: Animals; Antipsychotic Agents; Barium; Calmodulin; Cations, Divalent; Cell Membrane; Cells, Cultured; Chlorpromazine; Dose-Response Relationship, Drug; Electric Conductivity; Heart Ventricles; In Vitro Techniques; Ion Channels; Membrane Potentials; Myocardium; Rats; Sulfonamides; Trifluoperazine | 1995 |
Glucagon induces Ca2+-dependent increase of reduced pyridine nucleotides in mouse pancreatic beta-cells.
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Cells, Cultured; Chlorpromazine; Dose-Response Relationship, Drug; Fura-2; Glucagon; Glucose; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Inbred ICR; NAD; NADP; Sulfonamides; Trifluoperazine | 1996 |
Choroid plexus taurine transport.
Topics: Animals; Biological Transport, Active; Calcium; Calmodulin; Choroid Plexus; Cyclooxygenase Inhibitors; Dopamine Antagonists; Enzyme Inhibitors; Kinetics; Male; Mannitol; Niflumic Acid; Osmolar Concentration; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Sulfonamides; Taurine; Trifluoperazine | 1996 |
The role of calmodulin in the gravitropic response of the Arabidopsis thaliana agr-3 mutant.
Topics: Arabidopsis; Calmodulin; Gravitropism; Imidazoles; Mutation; Plant Roots; Sulfonamides; Trifluoperazine | 1996 |
Evidence for a role of calmodulin in calcium-induced noradrenaline release from permeated synaptosomes: effects of calmodulin antibodies and antagonists.
Topics: Animals; Antibodies; Calcium; Calmodulin; GAP-43 Protein; Imidazoles; Immunoglobulin G; Male; Membrane Glycoproteins; Nerve Tissue Proteins; Norepinephrine; Permeability; Rats; Rats, Wistar; Sulfonamides; Synaptosomes; Trifluoperazine | 1996 |
Regulation of capacitative calcium influx in cultured human mesangial cells: roles of protein kinase C and calmodulin.
Topics: Angiotensin II; Biological Transport; Calcium; Calmodulin; Cells, Cultured; Egtazic Acid; Enzyme Inhibitors; Glomerular Mesangium; Humans; Imidazoles; Ionomycin; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1996 |
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Membrane; Cell Polarity; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Dopamine Antagonists; Endocytosis; Golgi Apparatus; Horseradish Peroxidase; Immunoglobulin A; Iodine Radioisotopes; Kidney Tubules, Distal; Microscopy, Electron; Protein Kinase C; Ricin; Subcellular Fractions; Sulfonamides; Trifluoperazine; Vasodilator Agents | 1996 |
Bacterial infection induces nitric oxide synthase in human neutrophils.
Topics: Adult; Aged; Anti-Bacterial Agents; Arginine; Bacterial Infections; Blotting, Western; Canavanine; Cell Membrane; Citrulline; Female; Guanidines; Humans; Immunohistochemistry; Isoenzymes; Leukocyte Common Antigens; Male; Middle Aged; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiourea; Trifluoperazine; Urinary Tract Infections | 1997 |
The actions of calmodulin antagonists W-7 and TFP and of calcium on the gating kinetics of the calcium-activated large conductance potassium channel of the chara protoplasmic drop: a substate-sensitive analysis.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorophyta; Ion Channel Gating; Potassium Channels; Sulfonamides; Trifluoperazine | 1997 |
Prostaglandin production by guinea-pig endometrial cells: effects of caffeine and other modulators of intracellular calcium.
Topics: Animals; Berberine; Caffeine; Calcium; Cell Separation; Cells, Cultured; Colforsin; Dinoprost; Drug Interactions; Endometrium; Female; Gallic Acid; Guinea Pigs; Ryanodine; Sulfonamides; Thapsigargin; Theophylline; Trifluoperazine | 1997 |
Effects of calmodulin antagonists on calcium pump and cytosolic calcium level in human neutrophils.
Topics: Calcium; Calcium Chloride; Calcium-Transporting ATPases; Calmodulin; Cell Membrane; Cytosol; Humans; Indoles; Neutrophils; Sulfonamides; Trifluoperazine | 1997 |
Effects of calmodulin inhibitors on cyprid larvae of the barnacle, Balanus amphitrite.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Chlorpromazine; Cyclic AMP; Dose-Response Relationship, Drug; Imidazoles; Immunoblotting; Larva; Metamorphosis, Biological; Myosin-Light-Chain Kinase; Phosphodiesterase Inhibitors; Sulfonamides; Thoracica; Trifluoperazine; Vinca Alkaloids | 1998 |
Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts.
Topics: Calmodulin; Cervix Uteri; Collagenases; Concanavalin A; Enzyme Precursors; Female; Fibroblasts; Gelatinases; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; RNA, Messenger; Sulfonamides; Trifluoperazine | 1998 |
Sodium-gated cation channel implicated in the activation of lobster olfactory receptor neurons.
Topics: Animals; Axons; Calmodulin; Cells, Cultured; Dendrites; Evoked Potentials; Membrane Potentials; Nephropidae; Odorants; Olfactory Pathways; Olfactory Receptor Neurons; Patch-Clamp Techniques; Reaction Time; Sodium; Sodium Channels; Sulfonamides; Trifluoperazine | 1998 |
Protein kinase C--catalyzed calponin phosphorylation in swine carotid arterial homogenate.
Topics: Animals; Antiemetics; Calcium; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Calponins; Carcinogens; Carotid Arteries; Chelating Agents; Diglycerides; Egtazic Acid; Electrophoresis; Enzyme Inhibitors; Imidazoles; Microfilament Proteins; Okadaic Acid; Organ Culture Techniques; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Staurosporine; Sulfonamides; Swine; Trifluoperazine; Vasodilator Agents | 1998 |
Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Coculture Techniques; Colchicine; Culture Media, Conditioned; Cytochalasin B; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Microscopy, Fluorescence; Monocytes; Nocodazole; Paclitaxel; Protein Kinase C; Sulfonamides; Thiazoles; Thiazolidines; Trifluoperazine; Tumor Necrosis Factor-alpha | 1998 |
Lack of calmodulin antagonism of melatonin in T-lymphocyte activation.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Dopamine Antagonists; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1; Ionomycin; Ionophores; Jurkat Cells; Kinetics; Lymphocyte Activation; Melatonin; Signal Transduction; Sulfonamides; T-Lymphocytes; Trifluoperazine | 1998 |
Partial biochemical characterization of nitric oxide synthase in the caudal spinal cord of the teleost Oreochromis niloticus.
Topics: Animals; Arginine; Brain; Calmodulin; Kinetics; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Spinal Cord; Sulfonamides; Tilapia; Trifluoperazine | 1998 |
Possible role of calmodulin in excystation of Giardia lamblia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcium; Calmodulin; Child; Enzyme Activation; Feces; Giardia lamblia; Giardiasis; Humans; Protein Kinase C; Sulfonamides; Trifluoperazine | 1998 |
Glucagon induces suppression of ATP-sensitive K+ channel activity through a Ca2+/calmodulin-dependent pathway in mouse pancreatic beta-cells.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Bucladesine; Calcium Signaling; Calmodulin; Chlorpromazine; Glucagon; Glucose; Ion Channel Gating; Ion Transport; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred ICR; Patch-Clamp Techniques; Photolysis; Potassium; Potassium Channel Blockers; Potassium Channels; Sulfonamides; Trifluoperazine | 1998 |
Calmodulin regulation of Ca2+ entry in Jurkat T cells.
Topics: Calcium; Calcium Channel Blockers; Calmodulin; Chlorpromazine; Dose-Response Relationship, Drug; Electroporation; Humans; Ion Transport; Jurkat Cells; Lymphocyte Activation; Promethazine; Sulfonamides; T-Lymphocytes; Thioridazine; Time Factors; Trifluoperazine | 1998 |
Evidence for calmodulin inter-domain compaction in solution induced by W-7 binding.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Solutions; Sulfonamides; Trifluoperazine; X-Ray Diffraction; Xenopus laevis | 1999 |
Regulation of the high-affinity H+/peptide cotransporter in renal LLC-PK1 cells.
Topics: Animals; Biological Transport; Calcium; Carrier Proteins; Cell Survival; Dipeptides; Enzyme Inhibitors; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Kinetics; LLC-PK1 Cells; Protein Kinase C; Signal Transduction; Staurosporine; Stereoisomerism; Sulfonamides; Swine; Symporters; Tetradecanoylphorbol Acetate; Trifluoperazine | 1999 |
Protein synthesis in presynaptic endings from squid brain: modulation by calcium ions.
Topics: Animals; Brain; Caffeine; Calcimycin; Calcium; Cytosol; Decapodiformes; Egtazic Acid; Ionomycin; Kinetics; Magnesium; Naphthalenes; Nerve Tissue Proteins; Presynaptic Terminals; Sulfonamides; Synaptosomes; Thapsigargin; Trifluoperazine | 1999 |
alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium; Calmodulin; Doxazosin; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Genes, fos; Imidazoles; Kinetics; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Transcription, Genetic; Trifluoperazine | 1999 |
Regulation of glycine transport in cultured Müller cells by Ca2+/calmodulin-dependent enzymes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Transport Systems, Neutral; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carrier Proteins; Cell Line; Chick Embryo; Enzyme Inhibitors; Glycine Plasma Membrane Transport Proteins; Imidazoles; Kinetics; Sulfonamides; Trifluoperazine | 1999 |
Expression of in vitro virulence by Entamoeba histolytica: effect of calmodulin inhibitors.
Topics: Animals; Calmodulin; Entamoeba histolytica; Erythrocytes; Humans; Mice; Phagocytosis; Sulfonamides; Trifluoperazine | 1999 |
Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Calmodulin; Glucose Transporter Type 1; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfonamides; Trifluoperazine | 2000 |
Ca2+-bound calmodulin forms a compact globular structure on binding four trifluoperazine molecules in solution.
Topics: Animals; Binding Sites; Calcium; Calmodulin; Kinetics; Rats; Recombinant Proteins; Solutions; Sulfonamides; Trifluoperazine; X-Ray Diffraction | 2000 |
Potassium depolarization-induced cAMP stimulates somatostatin mRNA levels in cultured diencephalic neurons.
Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Membrane; Cells, Cultured; Cyclic AMP; Diencephalon; Egtazic Acid; Enzyme Inhibitors; Female; Fetus; Intracellular Fluid; Neurons; Nifedipine; Potassium; Pregnancy; Rats; Rats, Wistar; RNA, Messenger; Somatostatin; Sulfonamides; Thionucleotides; Trifluoperazine | 2000 |
Effect of calmodulin antagonists on the compound action potential of the cochlea.
Topics: Action Potentials; Animals; Calmodulin; Cochlea; Differential Threshold; Guinea Pigs; Ischemia; Perfusion; Perilymph; Recovery of Function; Regional Blood Flow; Reperfusion; Sulfonamides; Trifluoperazine | 2000 |
Calcium and osmotic regulation of the Na+/H+ exchanger in neonatal ventricular myocytes.
Topics: Amiloride; Angiotensin II; Animals; Animals, Newborn; Calcium; Calmodulin; Cells, Cultured; CHO Cells; Choline; Cricetinae; Endothelin-1; Heart Ventricles; Imidazoles; Meglumine; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium-Hydrogen Exchangers; Sorbitol; Sulfonamides; Trifluoperazine; Water-Electrolyte Balance | 2000 |
Role of calcium and calmodulin in ciliary stimulation induced by acetylcholine.
Topics: Acetylcholine; Animals; Calcium; Calcium Signaling; Calmodulin; Cell Movement; Cells, Cultured; Cilia; Enzyme Inhibitors; Epithelium; Esophagus; Imidazoles; Muscarinic Antagonists; Rana ridibunda; Receptors, Muscarinic; Sulfonamides; Trifluoperazine | 2001 |
Voltage dependence of the [Ca2+](i) oscillations system, in the Mg2+ -stimulated oocyte of the prawn Palaemon serratus.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Dopamine Antagonists; Enzyme Inhibitors; Female; Fluorescent Dyes; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Magnesium; Male; Membrane Potentials; Microinjections; Oocytes; Palaemonidae; Patch-Clamp Techniques; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Trifluoperazine | 2001 |
Inhibition of T-cell invasion across cultured fibroblast monolayers by phenothiazine-related calmodulin inhibitors: impairment of lymphocyte motility by trifluoperazine and chlorpromazine, and alteration of the monolayer by pimozide.
Topics: Animals; Calmodulin; Cell Movement; Cells, Cultured; Chlorpromazine; Dopamine Antagonists; Haloperidol; Humans; Mice; Pimozide; Sulfonamides; T-Lymphocytes; Trifluoperazine; Tumor Cells, Cultured; Vasodilator Agents | 2001 |
Calmodulin antagonists inhibit T-type Ca(2+) currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction.
Topics: Acrosome Reaction; Animals; Calcium; Calcium Channels; Calmodulin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Male; Mice; Patch-Clamp Techniques; Spermatozoa; Sulfonamides; Time Factors; Trifluoperazine; Zona Pellucida | 2001 |
In vitro and in vivo protein phosphorylation in Avena sativa L. coleoptiles: effects of Ca2+, calmodulin antagonists, and auxin.
Topics: Avena; Calcium; Calmodulin; Chelating Agents; Chlorpromazine; Cotyledon; Egtazic Acid; Indoleacetic Acids; Phosphorylation; Plant Proteins; Sulfonamides; Trifluoperazine | 1986 |
Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Size; Enzyme Inhibitors; Erythroid Precursor Cells; Humans; Hypotonic Solutions; K562 Cells; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase C; Protein-Tyrosine Kinases; Sulfonamides; Taurine; Trifluoperazine | 2001 |
Calmodulin antagonists do not inhibit IK(Ca) channels of human erythrocytes.
Topics: Calcium; Calmodulin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Erythrocytes; Humans; Imidazoles; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Sulfonamides; Trifluoperazine | 2002 |
Calmodulin modulates the delay period between release of calcium from internal stores and activation of calcium influx via endogenous TRP1 channels.
Topics: Amino Acid Sequence; Animals; Bradykinin; Calcium; Calcium Channels; Calmodulin; CHO Cells; Cricetinae; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Molecular Sequence Data; Receptors, Cytoplasmic and Nuclear; RNA Interference; Sulfonamides; Thapsigargin; Time Factors; Trifluoperazine; TRPC Cation Channels | 2002 |
Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Death; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Enzyme Inhibitors; Fetus; Kinetics; Membrane Potentials; Neurons; NG-Nitroarginine Methyl Ester; Nifedipine; Nitriles; Pyrethrins; Rats; Sulfonamides; Tacrolimus; Trifluoperazine; Veratridine | 2003 |
Calmodulin antagonists suppress gap junction coupling in isolated Hensen cells of the guinea pig cochlea.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Electric Conductivity; Gap Junctions; Guinea Pigs; Membrane Potentials; Organ of Corti; Patch-Clamp Techniques; Peptides; Spectrometry, Fluorescence; Sulfonamides; Trifluoperazine | 2003 |
The role of calmodulin in the regulation of osteoclastogenesis.
Topics: Animals; Apoptosis; Calmodulin; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Gene Transfer Techniques; Glycoproteins; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Osteoprotegerin; Ovariectomy; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Sulfonamides; Tamoxifen; Time Factors; Trifluoperazine | 2003 |
Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.
Topics: Arachidonic Acid; Calcium; Calcium Channels; Calcium Signaling; Calmodulin; Cell Line, Tumor; Cytosol; HeLa Cells; Humans; Imidazoles; Sulfonamides; Trifluoperazine | 2004 |
Inhibition of MPP+-induced mitochondrial damage and cell death by trifluoperazine and W-7 in PC12 cells.
Topics: Animals; Antipsychotic Agents; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Caspase 3; Caspases; Cell Death; Cytochromes c; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Glutathione; Indicators and Reagents; Mitochondria; PC12 Cells; Permeability; Pyridinium Compounds; Rats; Reactive Oxygen Species; Rotenone; Sulfonamides; Trifluoperazine | 2005 |
Calmodulin is required for vasopressin-stimulated increase in cyclic AMP production in inner medullary collecting duct.
Topics: Adenylyl Cyclases; Animals; Arginine Vasopressin; Brain; Cadaverine; Calcium; Calmodulin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Inhibitors; GTP-Binding Proteins; Isoenzymes; Kidney Medulla; Kidney Tubules, Collecting; Male; Mice; Mice, Knockout; Molecular Structure; Protein Glutamine gamma Glutamyltransferase 2; Rats; Rats, Sprague-Dawley; Sulfonamides; Transglutaminases; Trifluoperazine | 2005 |
Response to darkness of late-responsive dark-inducible genes is positively regulated by leaf age and negatively regulated by calmodulin-antagonist-sensitive signalling in Arabidopsis thaliana.
Topics: Arabidopsis; Calmodulin; Darkness; Genes, Plant; Heterocyclic Compounds; Plant Leaves; Signal Transduction; Sulfonamides; Trifluoperazine | 2005 |
Differential effect of calmodulin antagonists on MG132-induced mitochondrial dysfunction and cell death in PC12 cells.
Topics: Animals; Calcium; Calmodulin; Caspase 3; Caspases; Cell Count; Cell Death; Cell Size; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Imidazoles; Leupeptins; Mitochondrial Diseases; PC12 Cells; Rats; Reactive Oxygen Species; Sulfonamides; Trifluoperazine | 2005 |
Calcium-induced quiescence of sperm motility in the bluegill (Lepomis macrochirus).
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Chlorides; Cytoplasm; Dose-Response Relationship, Drug; Drug Interactions; Male; Manganese Compounds; Nifedipine; Nimodipine; Osmosis; Osmotic Pressure; Perciformes; Ruthenium Red; Semen; Sperm Motility; Spermatozoa; Strontium; Sulfonamides; Trifluoperazine | 2007 |
Transcriptional effect of a calmodulin inhibitor, W-7, on the ligninolytic enzyme genes in Phanerochaete chrysosporium.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; DNA Primers; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genome, Fungal; Lignin; Peroxidases; Phanerochaete; Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Transcription, Genetic; Trifluoperazine | 2010 |
Signaling events leading to red-light-induced suppression of photomorphogenesis in wheat (Triticum aestivum).
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cytokinins; Gene Expression Regulation, Plant; Heterotrimeric GTP-Binding Proteins; Light; Phosphorylation; Plant Proteins; Seedlings; Signal Transduction; Sulfonamides; Trifluoperazine; Triticum | 2010 |
Calmodulin protects androgen receptor from calpain-mediated breakdown in prostate cancer cells.
Topics: Antineoplastic Agents; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calpain; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Ionophores; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Receptors, Androgen; Recombinant Proteins; RNA Interference; RNA, Messenger; Sulfonamides; Time Factors; Transfection; Trifluoperazine | 2011 |
Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Binding, Competitive; Bordetella pertussis; Calmodulin; Catalysis; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Fluorescence Resonance Energy Transfer; Humans; Imidazoles; Models, Molecular; Molecular Structure; Mutation; Protein Binding; Sulfonamides; Trifluoperazine; Virulence; Whooping Cough | 2012 |
Interrelationship between calmodulin (CaM) and H2O2 in abscisic acid-induced antioxidant defense in the seedlings of Panax ginseng.
Topics: Abscisic Acid; Antioxidants; Ascorbate Peroxidases; Calcium; Calmodulin; Glutathione Reductase; Hydrogen Peroxide; NADPH Oxidases; Onium Compounds; Panax; Reactive Oxygen Species; Seedlings; Sulfonamides; Superoxide Dismutase; Thiourea; Trifluoperazine | 2012 |
A novel calmodulin-like protein from the liver fluke, Fasciola hepatica.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Fasciola hepatica; Humans; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Sulfonamides; Trifluoperazine | 2012 |
Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin.
Topics: Animals; Biophysical Phenomena; Calmodulin; Calorimetry; Fas-Associated Death Domain Protein; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sulfonamides; Surface Plasmon Resonance; Tamoxifen; Thermodynamics; Trifluoperazine | 2013 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |