w 7 has been researched along with kn 62 in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (60.53) | 18.2507 |
| 2000's | 12 (31.58) | 29.6817 |
| 2010's | 3 (7.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayakawa, T; Hidaka, H; Ishiguro, H; Kitagawa, M; Kondo, T; Nakae, Y; Sakai, Y; Shibata, T; Sobajima, H; Tanikawa, M | 1 |
| Hagiwara, M; Hidaka, H; Kato, M | 1 |
| Gordon, PB; Holen, I; Seglen, PO | 1 |
| Hidaka, H; Hoshino, T; Mizutani, A; Shimizu, S; Yamane, T | 1 |
| Hidaka, H; Ishikawa, T; Tokumitsu, H | 1 |
| Hashiba, Y; Hidaka, H; Ishikawa, N | 1 |
| Golombek, DA; Ralph, MR | 1 |
| Ganguly, A; Haxton, M; Li, L | 1 |
| Terrian, DM; Ways, DK | 1 |
| Audette, M; Bouillon, M | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Kano, M; Nakabayashi, Y; Satoh, R | 1 |
| Dunlop, J; Ennis, C; Minchin, MC; Rossiter, J | 1 |
| Grabié, V; Scemama, JL; Seidel, ER | 1 |
| Grabie, V; Robertson, JB; Scemama, JL; Seidel, ER | 1 |
| Ekokoski, E; Törnquist, K | 1 |
| Chock, PB; Huang, CY; Tekle, E; Zhu, DM | 1 |
| Hidaka, H; Yokokura, H | 1 |
| Ikeuchi, Y; Nishizaki, T; Okada, Y | 1 |
| Hashimoto, Y; Higashihara, M; Kurokawa, K; Satoh, H; Sunaga, S; Togo, M; Watanabe, T | 1 |
| Hidaka, H; Naito, Y | 1 |
| Chen, J; Hoffman, BB; Hu, ZW; Lin, R | 1 |
| Gadea, A; López-Colomé, AM | 1 |
| Aikawa, R; Hayashi, D; Komuro, I; Kudoh, S; Mizukami, M; Nagai, R; Shibasaki, F; Shiojima, I; Toko, H; Yazaki, Y; Zhu, W; Zou, Y | 1 |
| Bhattacharya, A; Chandok, MR; Deswal, R; Pandey, GK; Sopory, SK; Yadav, N | 1 |
| Lankisch, TO; Mitamura, K; Nozu, F; Owyang, C; Tsunoda, Y; Yoshida, H | 1 |
| Hishinuma, S; Ogura, K | 1 |
| Higo, A; Katsura, M; Mohri, Y; Ohkuma, S; Shuto, K; Takesue, M; Tarumi, C; Tsujimura, A | 1 |
| Courjaret, R; Lapied, B | 1 |
| Basavappa, S; Chang, CB; Huang, CC; Lim, PH; Liu, JY | 1 |
| Arbogast, LA | 1 |
| Fukushi, H; Morishima, Y; Shirasaki, Y; Takano, H | 1 |
| Hackman, JC; Holohean, AM | 1 |
| Bliss, SP; Clay, CM; Farmerie, TA; Navratil, AM; Roberson, MS; Wolfe, MW; Xie, J | 1 |
| Kudo, T; Murakami, I; Sutou, S; Takahashi, S; Takeuchi, S | 1 |
| Tano, JY; Vazquez, G | 1 |
| Balezina, OP; Bogatcheva, PO | 1 |
| Cao, Y; Liu, R; Qu, L; Wang, P; Wang, W; Wang, X; Wang, Y; Yu, J; Yue, W; Zhang, Q | 1 |
2 review(s) available for w 7 and kn 62
| Article | Year |
|---|---|
Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cardiovascular System; Dihydroxyphenylalanine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Islets of Langerhans; Molecular Sequence Data; Molecular Structure; Muscle, Smooth; Myosin Light Chains; Neurons; Pancreas; Phosphorylation; Protein Kinase Inhibitors; Structure-Activity Relationship; Sulfonamides; Tyrosine 3-Monooxygenase | 1996 |
[Inhibitor of calmodulin and calmodulin dependent enzyme].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclic Nucleotide Phosphodiesterases, Type 1; Humans; Myosin-Light-Chain Kinase; Naphthalenes; Naphthalenesulfonates; Phenothiazines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Sulfonamides; Vinca Alkaloids | 1998 |
36 other study(ies) available for w 7 and kn 62
| Article | Year |
|---|---|
Effects of calmodulin inhibitors on amylase secretion from rat pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Calcium; Calmodulin; Isoquinolines; Male; Pancreas; Piperazines; Protein Kinase Inhibitors; Rats; Second Messenger Systems; Sulfonamides | 1992 |
Identification of a 80 kDa calmodulin-binding protein as a new Ca2+/calmodulin-dependent kinase by renaturation blotting assay (RBA).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Chromatography, Affinity; Cytosol; Isoquinolines; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Substrate Specificity; Sulfonamides | 1992 |
Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Autophagy; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cells, Cultured; Cytoskeleton; Ethers, Cyclic; Indole Alkaloids; Indoles; Isoquinolines; Kinetics; Liver; Male; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Raffinose; Rats; Rats, Inbred Strains; Sulfonamides; Tritium | 1992 |
Calcium ion regulates the release of lipase of Fusarium oxysporum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calmodulin; Fusarium; Isoquinolines; Kinetics; Lipase; Piperazines; Protein Kinase Inhibitors; Subcellular Fractions; Sulfonamides | 1991 |
[Calmodulin dependent regulation of smooth muscle contraction].
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Calmodulin; Isoquinolines; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Piperazines; Sulfonamides; Thyroxine | 1990 |
Effect of a new Ca2(+)-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Pressure; Calmodulin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Isoquinolines; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rats; Sulfonamides; Vasodilator Agents | 1990 |
Circadian responses to light: the calmodulin connection.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Circadian Rhythm; Cricetinae; Cyclic AMP Response Element-Binding Protein; Immunohistochemistry; Isoquinolines; Light; Male; Mesocricetus; Phosphorylation; Piperazines; Sulfonamides; Suprachiasmatic Nucleus | 1995 |
Inhibition of angiotensin II- and potassium-mediated aldosterone secretion by KN-62 suggests involvement of Ca(2+)-calmodulin dependent protein kinase II in aldosterone secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldosterone; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Isoquinolines; Kinetics; Piperazines; Potassium; Sulfonamides; Zona Glomerulosa | 1995 |
Persistent enhancement of sustained calcium-dependent glutamate release by phorbol esters: role of calmodulin-independent serine/threonine phosphorylation and actin disassembly.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Animals; Barium; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cytochalasin D; Ethers, Cyclic; Glutamates; Guinea Pigs; Hippocampus; Isoquinolines; Male; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Phosphotransferases; Piperazines; Protein Kinase C; Serine; Sphingosine; Staurosporine; Subcellular Fractions; Sulfonamides; Synaptosomes; Threonine | 1995 |
Retinoic acid-stimulated intercellular adhesion molecule-1 expression on SK-N-SH cells: calcium/calmodulin-dependent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Adhesion Molecules; Enzyme Activation; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Neuroblastoma; Piperazines; Protein Kinase C; Sulfonamides; Terpenes; Thapsigargin; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Ca2+/calmodulin-dependent regulation of the density of Na+ channels in embryonic chick skeletal muscle cells during their development in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Chick Embryo; Electrophysiology; Isoquinolines; Muscles; Piperazines; Sodium Channels; Sulfonamides | 1994 |
The effect of 3 calmodulin antagonists on K(+)-stimulated neurotransmitter release from rat cortical slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calmodulin; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Kinetics; Piperazines; Potassium; Rats; Serotonin; Sulfonamides; Trifluoperazine | 1993 |
Characterization of univectorial polyamine transport in duodenal crypt cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Azepines; Biological Transport; Calmodulin; Cell Line; Duodenum; Epithelium; Humans; Imidazoles; Isoquinolines; Kinetics; Naphthalenes; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Sulfonamides | 1993 |
Paraquat uptake in the cultured gastrointestinal epithelial cell line, IEC-6.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding, Competitive; Calmodulin; Cell Count; Cell Line; Intestinal Mucosa; Isoquinolines; Paraquat; Piperazines; Putrescine; Rats; Spermidine; Sulfonamides | 1993 |
Inhibition of agonist-mediated calcium entry by calmodulin antagonists and by the Ca2+/calmodulin kinase II inhibitor KN-62. Studies with thyroid FRTL-5 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Barium; Biological Transport; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Calmodulin; Cell Line; Depression, Chemical; Fluphenazine; Imidazoles; Isoquinolines; Membrane Potentials; Phenoxybenzamine; Piperazines; Rats; Sulfonamides; Terpenes; Thapsigargin; Thyroid Gland | 1996 |
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Maleimides; Marine Toxins; Molecular Sequence Data; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spectrometry, Fluorescence; Staurosporine; Sulfonamides | 1996 |
Repetitive applications of ATP potentiate potassium current by Ca2+/calmodulin kinase in cultured rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Hippocampus; Indoles; Ion Channel Gating; Isoquinolines; Maleimides; Neurons; Patch-Clamp Techniques; Potassium; Protein Kinase C; Rats; Signal Transduction; Sulfonamides | 1996 |
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
alpha1-adrenergic receptor activation of c-fos expression in transfected rat-1 fibroblasts: role of Ca2+.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic alpha-1 Receptor Antagonists; Animals; Calcium; Calmodulin; Doxazosin; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Genes, fos; Imidazoles; Kinetics; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Transcription, Genetic; Trifluoperazine | 1999 |
Regulation of glycine transport in cultured Müller cells by Ca2+/calmodulin-dependent enzymes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Transport Systems, Neutral; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carrier Proteins; Cell Line; Chick Embryo; Enzyme Inhibitors; Glycine Plasma Membrane Transport Proteins; Imidazoles; Kinetics; Sulfonamides; Trifluoperazine | 1999 |
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcimycin; Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Heart; Ionomycin; Kinetics; Models, Cardiovascular; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2000 |
A novel protein kinase from Brassica juncea stimulated by a protozoan calcium binding protein. Purification and partial characterization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brassica; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calmodulin; Chelating Agents; Egtazic Acid; Entamoeba histolytica; Histones; Immunoglobulin G; Intercellular Signaling Peptides and Proteins; Peptides; Phosphorylation; Phosphoserine; Plant Proteins; Protein Kinases; Protein Processing, Post-Translational; Protozoan Proteins; Recombinant Fusion Proteins; Staurosporine; Sulfonamides | 2000 |
A possible role for Ca(2+)/calmodulin-dependent protein kinase IV during pancreatic acinar stimulus-secretion coupling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Immunoblotting; Indole Alkaloids; Male; Myosin-Light-Chain Kinase; Pancreas; Phosphotransferases; Rats; Rats, Sprague-Dawley; Sincalide; Sulfonamides | 2000 |
Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclosporine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Okadaic Acid; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sulfonamides; Tacrolimus; Tumor Cells, Cultured | 2000 |
Mechanism for increase in expression of cerebral diazepam binding inhibitor mRNA by nicotine: involvement of L-type voltage-dependent calcium channels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anesthetics, Local; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Diazepam Binding Inhibitor; Dibucaine; Enzyme Inhibitors; Gene Expression; Hexamethonium; Lidocaine; Membrane Potentials; Mice; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; omega-Agatoxin IVA; omega-Conotoxin GVIA; Platelet Aggregation Inhibitors; Procainamide; RNA, Messenger; Sulfonamides; Tetrodotoxin; Tritium | 2000 |
Complex intracellular messenger pathways regulate one type of neuronal alpha-bungarotoxin-resistant nicotinic acetylcholine receptors expressed in insect neurosecretory cells (dorsal unpaired median neurons).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Bungarotoxins; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Imidazoles; Insecta; Insecticides; Isoquinolines; Median Nerve; Neonicotinoids; Neurons; Niacin; Nitro Compounds; Okadaic Acid; Permeability; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Nicotinic; Signal Transduction; Sulfonamides | 2001 |
Effects of calcium, calmodulin, protein kinase C and protein tyrosine kinases on volume-activated taurine efflux in human erythroleukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Size; Enzyme Inhibitors; Erythroid Precursor Cells; Humans; Hypotonic Solutions; K562 Cells; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase C; Protein-Tyrosine Kinases; Sulfonamides; Taurine; Trifluoperazine | 2001 |
Calmodulin and a cyclic nucleotide-dependent protein kinase facilitate the prolactin-induced increase in tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calmodulin; Cyclic Nucleotide-Regulated Protein Kinases; Dopamine; Enzyme Inhibitors; Female; Hypothalamus; Neurons; Prolactin; Rats; Rats, Sprague-Dawley; Sheep; Sulfonamides; Tyrosine 3-Monooxygenase | 2001 |
Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Death; Cells, Cultured; Cerebral Cortex; Egtazic Acid; Enzyme Inhibitors; Fetus; Kinetics; Membrane Potentials; Neurons; NG-Nitroarginine Methyl Ester; Nifedipine; Nitriles; Pyrethrins; Rats; Sulfonamides; Tacrolimus; Trifluoperazine; Veratridine | 2003 |
Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ergolines; Excitatory Amino Acid Antagonists; Gallopamil; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Indoles; Magnesium; Memantine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nifedipine; Protein Kinase C; Pyridines; Rana pipiens; Receptor, Serotonin, 5-HT2B; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Staurosporine; Sulfonamides; Tetrodotoxin | 2004 |
Gonadotropin-releasing hormone induction of extracellular-signal regulated kinase is blocked by inhibition of calmodulin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calmodulin; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Gonadotropin-Releasing Hormone; JNK Mitogen-Activated Protein Kinases; Luciferases; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins c-raf; Signal Transduction; Sulfonamides | 2005 |
Corticotropin-releasing hormone or dexamethasone regulates rat proopiomelanocortin transcription through Tpit/Pitx-responsive element in its promoter.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Gene Deletion; Gene Expression Regulation; Glucocorticoids; Homeodomain Proteins; Nifedipine; Paired Box Transcription Factors; Pro-Opiomelanocortin; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; T-Box Domain Proteins; Transfection | 2007 |
Requirement for non-regulated, constitutive calcium influx in macrophage survival signaling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Survival; Humans; I-kappa B Proteins; Imidazoles; Macrophages; NF-kappaB-Inducing Kinase; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides | 2011 |
Multidirectional effects of calmodulin kinase II on transmitter release in mature and newly formed mouse motor synapses.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Mice; Motor Endplate; Neurotransmitter Agents; Nitrendipine; Okadaic Acid; Phosphoric Monoester Hydrolases; Sulfonamides; Synapses; Synaptic Transmission | 2013 |
Nociceptin/orphanin FQ-induced inhibition of delayed rectifier potassium currents by calcium/calmodulin-dependent protein kinase type II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cells, Cultured; Enzyme Inhibitors; Female; Kinetics; Male; Membrane Potentials; Neurons; Nociceptin; Opioid Peptides; Parietal Lobe; Patch-Clamp Techniques; Potassium Channels; Rats, Wistar; Sulfonamides | 2014 |