Compounds > vx
Page last updated: 2024-08-23

vx and tabun

vx has been researched along with tabun in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.39)18.7374
1990's13 (28.26)18.2507
2000's12 (26.09)29.6817
2010's11 (23.91)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Dettbarn, WD; Gupta, RC1
Anderson, DR; Harris, LW; Koplovitz, I; Lennox, WJ; Stewart, JR1
Anderson, DR; Harris, LW; Lennox, WJ; Solana, RP; Talbot, BG1
Bide, RW; Parker, D; Sawyer, TW; Thomas, N; Weiss, MT1
Erhard, MH; Kühlmann, R; Lösch, U; Szinicz, L1
Eldefrawi, AT; Eldefrawi, ME; Silveira, CL1
Forster, JS; Hammond, PS1
Aguayo, LG; Albuquerque, EX; Idriss, MK; Rickett, DL1
Artursson, E; Bucht, G; Puu, G1
Désiré, B; Saint-André, S1
Dawson, RM; Gray, PJ1
Beers, ET; Glenn, JF; Rickett, DL1
Beck, HC; Benschop, HP; Van den Berg, GR1
Binenfeld, Z; Maksimović, M; Markov, V1
Koplovitz, I; Stewart, JR1
Ashani, Y; Cohen, E; Grunwald, J; Marcus, D; Papier, Y; Raveh, L1
Belkin, M; Solberg, Y1
Holstege, CP; Kirk, M; Sidell, FR1
Munro, N1
Maxwell, DM; Sweeney, RE1
Klein, R; Leikin, JB; Meislin, HW; Thomas, RG; Walter, FG1
Amundson, DE; Devereaux, A; Lazarus, AA; Parrish, JS1
Bueters, TJ; Danhof, M; Groen, B; IJzerman, AP; Van Helden, HP1
Lobert, S; Martin, T1
Kassa, J; Kuca, K1
Niven, AS; Roop, SA1
Newmark, J1
Cabal, J; Hrabinova, M; Jun, D; Kassa, J; Kuca, K1
Bajgar, J; Jun, D; Kuca, K1
Hrobak, PK1
Beauchamp, JL; Neidholdt, EL1
Estour, F; Lafont, O; Le Provost, R; Müller, S; Reiter, G; Tenberken, O; Thiermann, H; Wille, T; Worek, F1
Alamneh, Y; Biggemann, L; Costante, M; Doctor, BP; Garcia, G; Nambiar, MP; Nigam, S; Short, R; Soojhawon, I; Valiyaveettil, M1
Bahnson, BJ; Cerasoli, DM; Kirby, SD; Norris, JR; Richard Smith, J1
Babu, UM; Condon, P; Mendez, A; Sambursky, R; VanDine, R1
Esposito, EX; Madura, JD; Stouch, TR; Wymore, T1
Ashani, Y; Goldsmith, M; Leader, H; Seeger, T; Sussman, JS; Tawfik, D; Thiermann, H; Wille, T; Worek, F1
Kanamori-Kataoka, M; Seto, Y1
Aas, P; Enger, S; Mariussen, E; Myhrer, T1
Caetano, MS; da Cunha, EF; de Castro, AA; Mancini, DT; Ramalho, TC; Rocha, EP; Silva, TC1
Derat, E; Driant, T; Nachon, F; Ollivier, C; Renard, PY1
C C França, T; Cuya, T; da Silva, JAV; Gonçalves, ADS; Kuca, K; Ramalho, TC1
Gupta, AK; Kumar, V; Rana, H; Rao, VK; Raviraju, G1
Kalisiak, J; Kovarik, Z; Maček Hrvat, N; Radić, Z; Sharpless, KB; Šinko, G; Taylor, P1
Leif, RN; Valdez, CA1

Reviews

9 review(s) available for vx and tabun

ArticleYear
The role of excitotoxicity in organophosphorous nerve agents central poisoning.
    Trends in pharmacological sciences, 1997, Volume: 18, Issue:6

    Topics: Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Excitatory Amino Acid Antagonists; Humans; Neurons; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Receptors, N-Methyl-D-Aspartate; Sarin; Seizures; Soman; Synaptic Transmission

1997
Chemical warfare. Nerve agent poisoning.
    Critical care clinics, 1997, Volume: 13, Issue:4

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Disaster Planning; Emergency Medical Services; Humans; Nervous System Diseases; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Sarin; Soman

1997
Toxicity of the organophosphate chemical warfare agents GA, GB, and VX: implications for public protection.
    Environmental health perspectives, 1994, Volume: 102, Issue:1

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Environmental Pollutants; Humans; Lethal Dose 50; Organophosphates; Organothiophosphorus Compounds; Sarin

1994
A review of nerve agent exposure for the critical care physician.
    Critical care medicine, 2002, Volume: 30, Issue:10

    Topics: Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Humans; Nervous System; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Sarin; Soman

2002
Vesicants and nerve agents in chemical warfare. Decontamination and treatment strategies for a changed world.
    Postgraduate medicine, 2002, Volume: 112, Issue:4

    Topics: Antidotes; Arsenicals; Chemical Warfare; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Humans; Information Services; Internet; Irritants; Mustard Gas; Organophosphates; Organothiophosphorus Compounds; Primary Prevention; Protective Clothing; Sarin; Soman

2002
Chemical warfare. Toxicity of nerve agents.
    Critical care nurse, 2003, Volume: 23, Issue:5

    Topics: Antidotes; Chemical Warfare; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Humans; Nervous System; Organophosphates; Organothiophosphorus Compounds; Sarin

2003
Inhalational exposure to nerve agents.
    Respiratory care clinics of North America, 2004, Volume: 10, Issue:1

    Topics: Chemical Warfare Agents; Disaster Planning; Humans; Lung Diseases; Lung Injury; Organophosphates; Organothiophosphorus Compounds; Sarin; Soman; United States

2004
Therapy for nerve agent poisoning.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman

2004
Analysis of Organophosphorus-Based Nerve Agent Degradation Products by Gas Chromatography-Mass Spectrometry (GC-MS): Current Derivatization Reactions in the Analytical Chemist's Toolbox.
    Molecules (Basel, Switzerland), 2021, Jul-30, Volume: 26, Issue:15

    Topics: Alkylation; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methylation; Nerve Agents; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman

2021

Other Studies

37 other study(ies) available for vx and tabun

ArticleYear
Potential of memantine, D-tubocurarine, and atropine in preventing acute toxic myopathy induced by organophosphate nerve agents: soman, sarin, tabun and VX.
    Neurotoxicology, 1992,Fall, Volume: 13, Issue:3

    Topics: Acetylcholinesterase; Acute Disease; Animals; Atropine; Cholinesterase Inhibitors; Male; Memantine; Muscular Diseases; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarin; Soman; Tubocurarine

1992
Reduction by pyridostigmine pretreatment of the efficacy of atropine and 2-PAM treatment of sarin and VX poisoning in rodents.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin

1992
Physostigmine (alone and together with adjunct) pretreatment against soman, sarin, tabun and VX intoxication.
    Drug and chemical toxicology, 1991, Volume: 14, Issue:3

    Topics: Animals; Atropine; Benztropine; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organothiophosphorus Compounds; Physostigmine; Sarin; Soman; Trihexyphenidyl

1991
Efficacy of an oximate-based skin decontaminant against organophosphate nerve agents determined in vivo and in vitro.
    Toxicology, 1991, Volume: 67, Issue:3

    Topics: Acetylcholinesterase; Animals; Brain; Chick Embryo; Cholinesterase Inhibitors; Decontamination; Diacetyl; Female; Male; Neurons; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman

1991
Detection of the organophosphorus nerve agent soman by an ELISA using monoclonal antibodies.
    Archives of toxicology, 1990, Volume: 64, Issue:7

    Topics: Alcohols; Animals; Antibodies, Monoclonal; Antibody Specificity; Buffers; Chickens; Cholinesterase Inhibitors; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Goats; Humans; Mice; Mice, Inbred Strains; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Peroxidases; Rabbits; Soman; Stereoisomerism

1990
Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases.
    Toxicology and applied pharmacology, 1990, Volume: 103, Issue:3

    Topics: Animals; Cholinesterase Inhibitors; Dioxolanes; Dose-Response Relationship, Drug; Echothiophate Iodide; Insecticides; Male; Myocardium; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sarin; Soman; Tritium

1990
A microassay-based procedure for measuring low levels of toxic organophosphorus compounds through acetylcholinesterase inhibition.
    Analytical biochemistry, 1989, Aug-01, Volume: 180, Issue:2

    Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Isoflurophate; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Reference Standards; Soman; Spectrophotometry

1989
Organophosphate and carbamate compounds have pre- and postjunctional effects at the insect glutamatergic synapse.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Action Potentials; Animals; Cholinesterase Inhibitors; Glutamates; Glutamic Acid; Grasshoppers; Isoflurophate; Organophosphates; Organothiophosphorus Compounds; Physostigmine; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Tetrodotoxin

1986
Reactivation of nerve agent inhibited human acetylcholinesterases by HI-6 and obidoxime.
    Biochemical pharmacology, 1986, May-01, Volume: 35, Issue:9

    Topics: Acetylcholinesterase; Caudate Nucleus; Cholinesterase Reactivators; Edrophonium; Humans; Muscles; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Sarin; Soman; Stereoisomerism

1986
Inactivation of sarin and soman by cyclodextrins in vitro.
    Experientia, 1987, Apr-15, Volume: 43, Issue:4

    Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Cyclodextrins; Dextrins; gamma-Cyclodextrins; Kinetics; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Starch

1987
Kinetic constants for the inhibition of eel and rabbit brain acetylcholinesterase by some organophosphates and carbamates of military significance.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:1

    Topics: Animals; Brain; Carbamates; Chemical Warfare Agents; Cholinesterase Inhibitors; Eels; Kinetics; Neostigmine; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Physostigmine; Rabbits; Sarin; Soman

1987
Central respiratory effects versus neuromuscular actions of nerve agents.
    Neurotoxicology, 1986,Spring, Volume: 7, Issue:1

    Topics: Animals; Cats; Cholinesterase Inhibitors; Diaphragm; Female; Male; Neuromuscular Junction; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Respiratory Center; Respiratory Insufficiency; Sarin; Soman

1986
Stereochemical analysis of the nerve agents soman, sarin, tabun, and VX by proton NMR-spectroscopy with optically active shift reagents.
    Bulletin of environmental contamination and toxicology, 1984, Volume: 33, Issue:5

    Topics: Cholinesterase Inhibitors; Indicators and Reagents; Magnetic Resonance Spectroscopy; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Stereoisomerism

1984
[Direct reactions of pyridinium oximes with organophosphorus compounds].
    Arhiv za higijenu rada i toksikologiju, 1984, Volume: 35, Issue:3

    Topics: Chemical Phenomena; Chemical Warfare Agents; Chemistry; Drug Interactions; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Sarin; Soman

1984
Treatment of nerve gas poisoning.
    The Medical letter on drugs and therapeutics, 1995, May-12, Volume: 37, Issue:948

    Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman

1995
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
    Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms

1994
Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity. In vitro and in vivo quantitative characterization.
    Biochemical pharmacology, 1993, Jun-22, Volume: 45, Issue:12

    Topics: Animals; Antidotes; Butyrylcholinesterase; Cholinesterase Inhibitors; Half-Life; Humans; Male; Mice; Mice, Inbred ICR; Neutralization Tests; Organophosphates; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarin; Soman

1993
A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning.
    Mathematical biosciences, 1999, Volume: 160, Issue:2

    Topics: Acetylcholinesterase; Animals; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dichlorvos; Esterases; Isoflurophate; Lethal Dose 50; Models, Biological; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Sarin; Soman

1999
Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication.
    Archives of toxicology, 2002, Volume: 76, Issue:11

    Topics: Acetylcholine; Adenosine; Animals; Cholinesterase Inhibitors; Cholinesterases; Corpus Striatum; Male; Microdialysis; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Parathion; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Sarin

2002
In vitro reactivation of acetylcholinesterase using the oxime K027.
    Veterinary and human toxicology, 2004, Volume: 46, Issue:1

    Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship

2004
In vitro potency of H oximes (HI-6, HLö-7), the oxime BI-6, and currently used oximes (pralidoxime, obidoxime, trimedoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase.
    Journal of toxicology and environmental health. Part A, 2006, Volume: 69, Issue:15

    Topics: Acetylcholinesterase; Animals; Antidotes; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Obidoxime Chloride; Organophosphates; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime

2006
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:1

    Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime

2007
Nerve agents: implications for anesthesia providers.
    AANA journal, 2008, Volume: 76, Issue:2

    Topics: Antidotes; Atropine; Chemical Terrorism; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Humans; Muscarinic Antagonists; Nurse Anesthetists; Nurse's Role; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Sarin; Soman; Time Factors

2008
Ionization mechanism of the ambient pressure pyroelectric ion source (APPIS) and its applications to chemical nerve agent detection.
    Journal of the American Society for Mass Spectrometry, 2009, Volume: 20, Issue:11

    Topics: Atmospheric Pressure; Butylamines; Chemical Warfare Agents; Electrochemistry; Gases; Ions; Mass Spectrometry; Models, Chemical; Molecular Weight; Organophosphates; Organothiophosphorus Compounds; Oxygen; Phase Transition; Physical Phenomena; Protons; Sensitivity and Specificity; Sulfhydryl Compounds; Temperature; Volatilization; Water

2009
Detoxification of nerve agents by a substituted beta-cyclodextrin: application of a modified biological assay.
    Toxicology, 2009, Nov-30, Volume: 265, Issue:3

    Topics: Acetylcholinesterase; beta-Cyclodextrins; Biological Assay; Buffers; Chemical Warfare Agents; Cholinesterase Inhibitors; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Reference Standards; Reproducibility of Results; Sarin; Time Factors

2009
Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:1

    Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Dipeptidases; Humans; Hydrolysis; Isoflurophate; Kidney; Liver; Organophosphates; Organothiophosphorus Compounds; Recombinant Proteins; Sarin; Skin

2012
Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Amino Acid Substitution; Antidotes; Aryldialkylphosphatase; Catalytic Domain; Chemical Warfare Agents; Humans; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Paraoxon; Protein Engineering; Recombinant Proteins; Sarin; Soman; Substrate Specificity

2013
A 10-minute point-of-care assay for detection of blood protein adducts resulting from low level exposure to organophosphate nerve agents.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Adult; Blood Chemical Analysis; Blood Proteins; Chemical Warfare Agents; Cholinesterase Inhibitors; Cross Reactions; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Point-of-Care Systems; Sarin; Soman

2013
Exploring the physicochemical properties of oxime-reactivation therapeutics for cyclosarin, sarin, tabun, and VX inactivated acetylcholinesterase.
    Chemical research in toxicology, 2014, Jan-21, Volume: 27, Issue:1

    Topics: Acetylcholinesterase; Animals; Chemistry, Physical; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Mice; Models, Molecular; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Rats; Reproducibility of Results; Sarin; Structure-Activity Relationship

2014
Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro.
    Archives of toxicology, 2014, Volume: 88, Issue:6

    Topics: Acetylcholinesterase; Animals; Antidotes; Aryldialkylphosphatase; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Guinea Pigs; Injections, Intravenous; Male; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds

2014
Measurement of breakthrough volumes of volatile chemical warfare agents on a poly(2,6-diphenylphenylene oxide)-based adsorbent and application to thermal desorption-gas chromatography/mass spectrometric analysis.
    Journal of chromatography. A, 2015, Sep-04, Volume: 1410

    Topics: Adsorption; Chemical Warfare Agents; Gas Chromatography-Mass Spectrometry; Mustard Gas; Organophosphates; Organothiophosphorus Compounds; Phenols; Polymers; Sarin; Soman; Volatilization

2015
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
    Neurotoxicology, 2015, Volume: 50

    Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman

2015
Molecular Docking, Metal Substitution and Hydrolysis Reaction of Chiral Substrates of Phosphotriesterase.
    Combinatorial chemistry & high throughput screening, 2016, Volume: 19, Issue:4

    Topics: Aluminum; Catalytic Domain; Cholinesterase Inhibitors; Hydrolysis; Kinetics; Metals; Molecular Docking Simulation; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Phosphoric Triester Hydrolases; Sarin; Soman; Stereoisomerism

2016
On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach.
    Chembiochem : a European journal of chemical biology, 2017, 04-04, Volume: 18, Issue:7

    Topics: Acetylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Glutamic Acid; Histidine; Models, Chemical; Molecular Structure; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Protons; Quantum Theory; Serine

2017
The role of the oximes HI-6 and HS-6 inside human acetylcholinesterase inhibited with nerve agents: a computational study.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:13

    Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Agents; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin

2018
Highly selective and sensitive chromogenic detection of nerve agents (sarin, tabun and VX): a multianalyte detection approach.
    Chemical communications (Cambridge, England), 2017, Nov-30, Volume: 53, Issue:96

    Topics: Ferrous Compounds; Fluorescent Dyes; Molecular Structure; Nerve Agents; Organophosphates; Organothiophosphorus Compounds; Sarin

2017
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; GPI-Linked Proteins; Humans; Kinetics; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Protein Conformation; Sarin; Structure-Activity Relationship

2020