vx has been researched along with cyclohexyl methylphosphonofluoridate in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, RM; Gray, PJ | 1 |
| Feng, C; Xie, J | 1 |
| Benton, BJ; Crouse, CL; Dabisch, PA; Jakubowski, EM; Matson, KL; McGuire, JM; Mioduszewski, RJ; Sommerville, DR; Thomson, SA | 1 |
| Becker, G; Gutzeit, D; Kawan, A; Szinicz, L; Worek, F | 1 |
| Bajgar, J; Jun, D; Kuca, K | 1 |
| Aurbek, N; Mann, T; Pearce, P; Thiermann, H; Wetherell, J; Worek, F | 1 |
| Koplovitz, I; Maxwell, DM; Sweeney, RE; Worek, F | 1 |
| Dabisch, PA; Horsmon, MS; Miller, DB; Mioduszewski, RJ; Muse, WT; Sommerville, DR; Taylor, JT; Thomson, S | 1 |
| McDonough, JH; Shih, TM; Skovira, JW | 1 |
| Estour, F; Lafont, O; Le Provost, R; Müller, S; Reiter, G; Tenberken, O; Thiermann, H; Wille, T; Worek, F | 1 |
| Guarisco, JA; Kan, RK; McDonough, JH; Myers, TM; Shih, TM | 1 |
| Esposito, EX; Madura, JD; Stouch, TR; Wymore, T | 1 |
| Ashani, Y; Goldsmith, M; Leader, H; Seeger, T; Sussman, JS; Tawfik, D; Thiermann, H; Wille, T; Worek, F | 1 |
| Coleman, RM; Crow, BS; Hamelin, EI; Jakubowski, EM; Johnson, RC; Lawrence, RJ; Schulze, ND; Shaner, RL | 1 |
| Blake, TA; Brewer, BN; Carter, MD; Crenshaw, MD; Crow, BS; Evans, RA; Garton, JW; Johnson, RC; Pantazides, BG; Perez, JW; Quiñones-González, J; Read, RW; Riches, JR; Stubbs, SJ; Thomas, JD; Tomcik, DJ; Watson, CM | 1 |
| Aas, P; Enger, S; Mariussen, E; Myhrer, T | 1 |
| C C França, T; Cuya, T; da Silva, JAV; Gonçalves, ADS; Kuca, K; Ramalho, TC | 1 |
| Kalisiak, J; Kovarik, Z; Maček Hrvat, N; Radić, Z; Sharpless, KB; Šinko, G; Taylor, P | 1 |
| Escher, B; Job, L; Köhler, A; Skerra, A; Worek, F | 1 |
| Garrett, TJ; Goldberger, BA; Rubin, KM | 1 |
| Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM | 1 |
| Enright, HA; Lao, V; Lau, EY; Malfatti, MA; Mayer, BP; Valdez, CA; Williams, AM | 1 |
22 other study(ies) available for vx and cyclohexyl methylphosphonofluoridate
| Article | Year |
|---|---|
Kinetic constants for the inhibition of eel and rabbit brain acetylcholinesterase by some organophosphates and carbamates of military significance.
Topics: Animals; Brain; Carbamates; Chemical Warfare Agents; Cholinesterase Inhibitors; Eels; Kinetics; Neostigmine; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Physostigmine; Rabbits; Sarin; Soman | 1987 |
[Determination of five nerve agents in contaminated serum by gas chromatography].
Topics: Chemical Warfare Agents; Chromatography, Gas; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Serum; Soman | 2005 |
Effects of whole-body VX vapor exposure on lethality in rats.
Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarin; Sex Characteristics; Volatilization | 2006 |
Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro.
Topics: Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Half-Life; Kinetics; Models, Chemical; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Spectrophotometry, Ultraviolet | 2007 |
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime | 2007 |
Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase.
Topics: Acetylcholinesterase; Aging; Algorithms; Animals; Butyrylcholinesterase; Catalysis; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Humans; Kinetics; Models, Animal; Molecular Structure; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Paraoxon; Swine; Swine, Miniature | 2008 |
A structure-activity analysis of the variation in oxime efficacy against nerve agents.
Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Linear Models; Male; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship | 2008 |
Gender difference in the miotic potency of soman vapor in rats.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Eye; Female; Infrared Rays; Male; Miosis; Models, Animal; Organophosphorus Compounds; Organothiophosphorus Compounds; Pupil; Rats; Rats, Sprague-Dawley; Sex Characteristics; Soman | 2008 |
Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Longevity; Male; Neurotoxicity Syndromes; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Salivation; Sarin; Seizures; Tears | 2009 |
Detoxification of nerve agents by a substituted beta-cyclodextrin: application of a modified biological assay.
Topics: Acetylcholinesterase; beta-Cyclodextrins; Biological Assay; Buffers; Chemical Warfare Agents; Cholinesterase Inhibitors; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Reference Standards; Reproducibility of Results; Sarin; Time Factors | 2009 |
The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.
Topics: Animals; Cholinesterase Reactivators; Guinea Pigs; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Pralidoxime Compounds; Prodrugs; Sarin; Seizures | 2011 |
Exploring the physicochemical properties of oxime-reactivation therapeutics for cyclosarin, sarin, tabun, and VX inactivated acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Chemistry, Physical; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Mice; Models, Molecular; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Rats; Reproducibility of Results; Sarin; Structure-Activity Relationship | 2014 |
Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro.
Topics: Acetylcholinesterase; Animals; Antidotes; Aryldialkylphosphatase; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Guinea Pigs; Injections, Intravenous; Male; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds | 2014 |
Quantitation of five organophosphorus nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry.
Topics: Ammonium Compounds; Biotransformation; Buffers; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Fluorides; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Limit of Detection; Organophosphorus Compounds; Organothiophosphorus Compounds; Quaternary Ammonium Compounds; Sarin; Solid Phase Extraction; Soman; Tandem Mass Spectrometry | 2014 |
Simultaneous measurement of tabun, sarin, soman, cyclosarin, VR, VX, and VM adducts to tyrosine in blood products by isotope dilution UHPLC-MS/MS.
Topics: Blood Chemical Analysis; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Reproducibility of Results; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization; Time Factors; Tyrosine | 2014 |
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman | 2015 |
The role of the oximes HI-6 and HS-6 inside human acetylcholinesterase inhibited with nerve agents: a computational study.
Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Agents; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin | 2018 |
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; GPI-Linked Proteins; Humans; Kinetics; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Protein Conformation; Sarin; Structure-Activity Relationship | 2020 |
A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
Topics: Antidotes; Bacterial Proteins; Caulobacteraceae; Drug Stability; Enzyme Stability; Hot Temperature; Mutation; Nerve Agents; Organophosphate Poisoning; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidation-Reduction; Phosphoric Triester Hydrolases; Protein Denaturation; Recombinant Proteins; Sarin; Soman | 2020 |
Detection of Chemical Weapon Nerve Agents in Bone by Liquid Chromatography-Mass Spectrometry.
Topics: Animals; Bone and Bones; Chemical Warfare Agents; Chromatography, Liquid; Humans; Limit of Detection; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Swine | 2020 |
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors | 2020 |
Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX.
Topics: Chemical Warfare Agents; Cyclodextrins; Medical Countermeasures; Molecular Dynamics Simulation; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphorus; Soman | 2023 |