Page last updated: 2024-08-23

vx and cyclohexyl methylphosphonofluoridate

vx has been researched along with cyclohexyl methylphosphonofluoridate in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's0 (0.00)18.2507
2000's9 (40.91)29.6817
2010's7 (31.82)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Dawson, RM; Gray, PJ1
Feng, C; Xie, J1
Benton, BJ; Crouse, CL; Dabisch, PA; Jakubowski, EM; Matson, KL; McGuire, JM; Mioduszewski, RJ; Sommerville, DR; Thomson, SA1
Becker, G; Gutzeit, D; Kawan, A; Szinicz, L; Worek, F1
Bajgar, J; Jun, D; Kuca, K1
Aurbek, N; Mann, T; Pearce, P; Thiermann, H; Wetherell, J; Worek, F1
Koplovitz, I; Maxwell, DM; Sweeney, RE; Worek, F1
Dabisch, PA; Horsmon, MS; Miller, DB; Mioduszewski, RJ; Muse, WT; Sommerville, DR; Taylor, JT; Thomson, S1
McDonough, JH; Shih, TM; Skovira, JW1
Estour, F; Lafont, O; Le Provost, R; Müller, S; Reiter, G; Tenberken, O; Thiermann, H; Wille, T; Worek, F1
Guarisco, JA; Kan, RK; McDonough, JH; Myers, TM; Shih, TM1
Esposito, EX; Madura, JD; Stouch, TR; Wymore, T1
Ashani, Y; Goldsmith, M; Leader, H; Seeger, T; Sussman, JS; Tawfik, D; Thiermann, H; Wille, T; Worek, F1
Coleman, RM; Crow, BS; Hamelin, EI; Jakubowski, EM; Johnson, RC; Lawrence, RJ; Schulze, ND; Shaner, RL1
Blake, TA; Brewer, BN; Carter, MD; Crenshaw, MD; Crow, BS; Evans, RA; Garton, JW; Johnson, RC; Pantazides, BG; Perez, JW; Quiñones-González, J; Read, RW; Riches, JR; Stubbs, SJ; Thomas, JD; Tomcik, DJ; Watson, CM1
Aas, P; Enger, S; Mariussen, E; Myhrer, T1
C C França, T; Cuya, T; da Silva, JAV; Gonçalves, ADS; Kuca, K; Ramalho, TC1
Kalisiak, J; Kovarik, Z; Maček Hrvat, N; Radić, Z; Sharpless, KB; Šinko, G; Taylor, P1
Escher, B; Job, L; Köhler, A; Skerra, A; Worek, F1
Garrett, TJ; Goldberger, BA; Rubin, KM1
Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM1
Enright, HA; Lao, V; Lau, EY; Malfatti, MA; Mayer, BP; Valdez, CA; Williams, AM1

Other Studies

22 other study(ies) available for vx and cyclohexyl methylphosphonofluoridate

ArticleYear
Kinetic constants for the inhibition of eel and rabbit brain acetylcholinesterase by some organophosphates and carbamates of military significance.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:1

    Topics: Animals; Brain; Carbamates; Chemical Warfare Agents; Cholinesterase Inhibitors; Eels; Kinetics; Neostigmine; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Physostigmine; Rabbits; Sarin; Soman

1987
[Determination of five nerve agents in contaminated serum by gas chromatography].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:1

    Topics: Chemical Warfare Agents; Chromatography, Gas; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Serum; Soman

2005
Effects of whole-body VX vapor exposure on lethality in rats.
    Inhalation toxicology, 2006, Volume: 18, Issue:14

    Topics: Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarin; Sex Characteristics; Volatilization

2006
Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro.
    Archives of toxicology, 2007, Volume: 81, Issue:6

    Topics: Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Half-Life; Kinetics; Models, Chemical; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Spectrophotometry, Ultraviolet

2007
Currently used cholinesterase reactivators against nerve agent intoxication: comparison of their effectivity in vitro.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:1

    Topics: Animals; Brain; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Obidoxime Chloride; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Sarin; Soman; Tissue Extracts; Trimedoxime

2007
Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase.
    Toxicology, 2008, Feb-03, Volume: 244, Issue:1

    Topics: Acetylcholinesterase; Aging; Algorithms; Animals; Butyrylcholinesterase; Catalysis; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Humans; Kinetics; Models, Animal; Molecular Structure; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Paraoxon; Swine; Swine, Miniature

2008
A structure-activity analysis of the variation in oxime efficacy against nerve agents.
    Toxicology and applied pharmacology, 2008, Sep-01, Volume: 231, Issue:2

    Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Linear Models; Male; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship

2008
Gender difference in the miotic potency of soman vapor in rats.
    Cutaneous and ocular toxicology, 2008, Volume: 27, Issue:2

    Topics: Acetylcholinesterase; Analysis of Variance; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Eye; Female; Infrared Rays; Male; Miosis; Models, Animal; Organophosphorus Compounds; Organothiophosphorus Compounds; Pupil; Rats; Rats, Sprague-Dawley; Sex Characteristics; Soman

2008
Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
    Archives of toxicology, 2009, Volume: 83, Issue:12

    Topics: Acetylcholinesterase; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Longevity; Male; Neurotoxicity Syndromes; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Salivation; Sarin; Seizures; Tears

2009
Detoxification of nerve agents by a substituted beta-cyclodextrin: application of a modified biological assay.
    Toxicology, 2009, Nov-30, Volume: 265, Issue:3

    Topics: Acetylcholinesterase; beta-Cyclodextrins; Biological Assay; Buffers; Chemical Warfare Agents; Cholinesterase Inhibitors; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Reference Standards; Reproducibility of Results; Sarin; Time Factors

2009
The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs.
    Toxicology mechanisms and methods, 2011, Volume: 21, Issue:1

    Topics: Animals; Cholinesterase Reactivators; Guinea Pigs; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Pralidoxime Compounds; Prodrugs; Sarin; Seizures

2011
Exploring the physicochemical properties of oxime-reactivation therapeutics for cyclosarin, sarin, tabun, and VX inactivated acetylcholinesterase.
    Chemical research in toxicology, 2014, Jan-21, Volume: 27, Issue:1

    Topics: Acetylcholinesterase; Animals; Chemistry, Physical; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Mice; Models, Molecular; Molecular Structure; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Rats; Reproducibility of Results; Sarin; Structure-Activity Relationship

2014
Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro.
    Archives of toxicology, 2014, Volume: 88, Issue:6

    Topics: Acetylcholinesterase; Animals; Antidotes; Aryldialkylphosphatase; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Guinea Pigs; Injections, Intravenous; Male; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds

2014
Quantitation of five organophosphorus nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:21

    Topics: Ammonium Compounds; Biotransformation; Buffers; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Fluorides; Humans; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Limit of Detection; Organophosphorus Compounds; Organothiophosphorus Compounds; Quaternary Ammonium Compounds; Sarin; Solid Phase Extraction; Soman; Tandem Mass Spectrometry

2014
Simultaneous measurement of tabun, sarin, soman, cyclosarin, VR, VX, and VM adducts to tyrosine in blood products by isotope dilution UHPLC-MS/MS.
    Analytical chemistry, 2014, Oct-21, Volume: 86, Issue:20

    Topics: Blood Chemical Analysis; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Humans; Organophosphorus Compounds; Organothiophosphorus Compounds; Reproducibility of Results; Sarin; Soman; Spectrometry, Mass, Electrospray Ionization; Time Factors; Tyrosine

2014
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
    Neurotoxicology, 2015, Volume: 50

    Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Lethal Dose 50; Levetiracetam; Male; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Piracetam; Procyclidine; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Soman

2015
The role of the oximes HI-6 and HS-6 inside human acetylcholinesterase inhibited with nerve agents: a computational study.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:13

    Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Agents; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin

2018
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Enzyme Activation; GPI-Linked Proteins; Humans; Kinetics; Nerve Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Protein Conformation; Sarin; Structure-Activity Relationship

2020
A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
    Toxicology letters, 2020, Mar-15, Volume: 321

    Topics: Antidotes; Bacterial Proteins; Caulobacteraceae; Drug Stability; Enzyme Stability; Hot Temperature; Mutation; Nerve Agents; Organophosphate Poisoning; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidation-Reduction; Phosphoric Triester Hydrolases; Protein Denaturation; Recombinant Proteins; Sarin; Soman

2020
Detection of Chemical Weapon Nerve Agents in Bone by Liquid Chromatography-Mass Spectrometry.
    Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4

    Topics: Animals; Bone and Bones; Chemical Warfare Agents; Chromatography, Liquid; Humans; Limit of Detection; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Swine

2020
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors

2020
Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Chemical Warfare Agents; Cyclodextrins; Medical Countermeasures; Molecular Dynamics Simulation; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphorus; Soman

2023