vx 497 and ribavirin
vx 497 has been researched along with ribavirin in 10 studies
Compound Research Comparison
Studies (vx 497) | Trials (vx 497) | Recent Studies (post-2010) (vx 497) | Studies (ribavirin) | Trials (ribavirin) | Recent Studies (post-2010) (ribavirin) |
---|---|---|---|---|---|
25 | 3 | 7 | 12,316 | 1,880 | 5,443 |
Research
Studies (10)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 7 (70.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 3 (30.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Gahan, ME; Keller, PA; Mahalingam, S; Stevens, AJ | 1 |
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT | 1 |
Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Jain, J; Kwong, AD; Markland, W; McQuaid, TJ | 1 |
McHutchison, JG; Shad, JA | 1 |
Baroudy, BM; Liu, R; Malcolm, BA; Reyes, GR; Zhou, S | 1 |
Alam, J; Bengtsson, L; Bronowicki, JP; Garg, V; Grange, JD; Horsmans, Y; Marcellin, P; McNair, L; Nevens, F; Purdy, S; Vetter, D | 1 |
Pockros, PJ; Shields, WW | 1 |
Aalyson, M; Afdhal, N; Alam, J; Bengtsson, L; Bonkovsky, HL; Chandorkar, G; Gharakhanian, S; Gordon, SC; Harding, M; Kauffman, R; Lawitz, E; Lee, WM; McHutchison, JG; McNair, L; Poordad, F; Rustgi, VK | 1 |
Reviews
3 review(s) available for vx 497 and ribavirin
Article | Year |
---|---|
The medicinal chemistry of dengue fever.
Topics: Antiviral Agents; Dengue; Dengue Virus; Humans; Models, Molecular; Viral Proteins | 2009 |
Drugs for the Treatment of Zika Virus Infection.
Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection | 2020 |
Current and future therapies of hepatitis C.
Topics: Antiviral Agents; Carbamates; Drug Therapy, Combination; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Hepacivirus; Hepatitis C, Chronic; Humans; Immunization, Passive; Immunologic Factors; IMP Dehydrogenase; Interferon-alpha; Phenylurea Compounds; Ribavirin; RNA, Viral | 2001 |
Trials
2 trial(s) available for vx 497 and ribavirin
Article | Year |
---|---|
Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C.
Topics: Adult; Antiviral Agents; Carbamates; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Phenylurea Compounds; Placebos; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome | 2007 |
Merimepodib, pegylated interferon, and ribavirin in genotype 1 chronic hepatitis C pegylated interferon and ribavirin nonresponders.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Carbamates; Double-Blind Method; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Phenylurea Compounds; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2009 |
Other Studies
5 other study(ies) available for vx 497 and ribavirin
Article | Year |
---|---|
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon.
Topics: Animals; Antiviral Agents; Carbamates; Cattle; Cell Line; Cytopathogenic Effect, Viral; Electrophoresis; Enzyme Inhibitors; Fibroblasts; Guanosine; Humans; IMP Dehydrogenase; Interferon-alpha; Mice; Molecular Weight; Phenylurea Compounds; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Signal Transduction; Viral Plaque Assay; Virus Replication; Viruses | 2000 |
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.
Topics: Antimetabolites; Carbamates; Cell Line, Transformed; Enzyme Inhibitors; Genome, Viral; Guanosine; Hepacivirus; Humans; IMP Dehydrogenase; Mutation; Mycophenolic Acid; Phenylurea Compounds; Replicon; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA; RNA, Viral; Transfection; Virus Replication | 2003 |
Ribavirin analogs.
Topics: Anemia, Hemolytic; Antiviral Agents; Carbamates; Hepacivirus; Hepatitis C; Humans; IMP Dehydrogenase; Mycophenolic Acid; Phenylurea Compounds; Ribavirin | 2009 |